What are the cheapest airlines flying from Des Moines to Gainesville round-trip?

Flying on Delta is currently your cheapest option to Gainesville, with prices starting at $452. Another option worth looking into is American Airlines, starting at $457 round trip. Delta is priced at 25% lower than the current average price of a flight leaving 3 months from now.

What is the cheapest day to fly from Des Moines to Gainesville?

Travelers seeking maximum savings on their Des Moines to Gainesville flight should consider departing on Tuesday at noon when fares are most often at their lowest. Friday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

What is the cheapest day to fly round-trip from Des Moines to Gainesville?

It’s generally more expensive to depart on a Tuesday, if you have to leave on this day you can still search on Cheapflights to find great options that meet your needs.

What is the cheapest month to fly from Des Moines to Gainesville?

May can be a great time to fly to Gainesville from Des Moines with a flight ticket averaging about $610. Cheapflights users have found deals in the month of May for as cheap as $400. The most expensive prices can be found in the month of July.

What is the cheapest time of day to fly from DSM to GNV?

It’s typically best to fly out from Des Moines to Gainesville at noon. Doing so could potentially save you 41% on the flight price compared to flying in the morning, which is usually more expensive.

Most accurate provider : When it comes to deals on Des Moines-Gainesville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Gainesville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Gainesville flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Des Moines-Gainesville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Gainesville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from Des Moines to Gainesville that include hotel bookings?

Yes. In addition to deals on Des Moines to Gainesville flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Des Moines to Gainesville?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Gainesville.

Can I find deals for business class flights from Des Moines to Gainesville?

Yes. Cheapflights offers flight deals from Des Moines to Gainesville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$254+ Flights from Des Moines to Gainesville

Home Search by date Vacation packages Hotels Flight deals Car rental Travel tips & news

Find cheap flights from Des Moines to Gainesville with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Des Moines to Gainesville

Most accurate provider	FlightHub 3 stars
Most trusted provider	FlightHub 3 stars
Round-trip from	$452 (Delta)
One-way from	$254 (American Airlines)
Popular in	July
Cheapest in	May

Provider with most accurate pricing for Des Moines-Gainesville Regional flight deals.

Search Deals

Provider most trusted by Cheapflights users for Des Moines-Gainesville Regional flights.

Search Deals

From Des Moines to Gainesville Regional

Search Deals

One-way flight from Des Moines to Gainesville Regional

Search Deals

High demand for flights, 24% potential price rise

Search Deals

Best time to find cheap flights, 4% potential price drop

Search Deals

Find flight deals from Des Moines to Gainesville

Cheapest flights from Des Moines to Gainesville
Explore the most affordable flight options available from Des Moines to Gainesville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 16, 2025.

Tue 2/2510:32 amDSM - GNV

2 stops8h 43mDelta

Fri 2/286:00 amGNV - DSM

1 stop5h 40mDelta

Deal found 1/16

$452

Tue 2/2512:15 pmDSM - GNV

2 stops10h 09mAmerican Airlines

Fri 2/2811:18 amGNV - DSM

2 stops9h 03mAmerican Airlines

Deal found 1/16

$457

Best flights from Des Moines to Gainesville
Discover carefully curated flight deals from Des Moines to Gainesville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated January 16, 2025.

Tue 2/2510:32 amDSM - GNV

2 stops8h 43mDelta

Fri 2/286:00 amGNV - DSM

1 stop5h 40mDelta

Deal found 1/16

$452

Tue 2/2512:15 pmDSM - GNV

2 stops10h 09mAmerican Airlines

Fri 2/2811:18 amGNV - DSM

2 stops9h 03mAmerican Airlines

Deal found 1/16

$457

Last-minute flights from Des Moines to Gainesville
Discover last-minute flight deals from Des Moines to Gainesville. Data last updated January 16, 2025 and is based on user searches.

Tue 2/2510:32 amDSM - GNV

2 stops8h 43mDelta

Fri 2/286:00 amGNV - DSM

1 stop5h 40mDelta

Deal found 1/16

$452

Tue 2/2512:15 pmDSM - GNV

2 stops10h 09mAmerican Airlines

Fri 2/2811:18 amGNV - DSM

2 stops9h 03mAmerican Airlines

Deal found 1/16

$457

One-way flights from Des Moines to Gainesville
Search for one-way flight options from Des Moines to Gainesville. Find affordable one-way fares based on user searches. Data last updated January 16, 2025.

Thu 4/36:40 amDSM - GNV

1 stop7h 44mAmerican Airlines

Deal found 1/15

$254

Find flights from Des Moines to Gainesville within your budget

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesGainesville

DSM - GNV

DSMGNV

Des Moines

Tue 2/25

10:32 am-8:15 pm

2 stops8h 43m

Gainesville Regional

Fri 2/28

6:00 am-10:40 am

1 stop5h 40m

$452

Des MoinesGainesville

DSM - GNV

DSMGNV

Des Moines

Tue 2/25

12:15 pm-11:24 pm

2 stops10h 09m

Gainesville Regional

Fri 2/28

11:18 am-7:21 pm

2 stops9h 03m

$457

Des MoinesGainesville

DSM - GNV

DSMGNV

Des Moines

Thu 4/3

6:40 am-3:24 pm

1 stop7h 44m

$254

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/15

Compare providers for flights from Des Moines to Gainesville

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Gainesville in January.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy1 star	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*3 stars
eDreams	Price Accuracy3 stars	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Des Moines-Gainesville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Gainesville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Gainesville flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Des Moines-Gainesville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Gainesville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Gainesville

Have a flexible travel schedule? Discover the best time to fly to Gainesville from Des Moines with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Des Moines to Gainesville

Get recent, data-driven insights about flights from Des Moines to Gainesville including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Des Moines to Gainesville?

Currently, January is the cheapest month in which you can book a flight from Des Moines to Gainesville (average of $359). Flying from Des Moines to Gainesville in November is currently the most expensive (average of $510). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Rainfall in Gainesville by month

In terms of precipitation, rainfall in Gainesville ranges from 2.1 - 7.1 inches per month. June is typically the wettest month, when rainfall can reach 7.1 in. November is typically the driest time to visit Gainesville when rainfall is around 2.1 in.

Temperature in Gainesville by month

If weather is an important factor for your trip to Gainesville, use this chart to help with planning. For those seeking warmer temperatures, June is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 53.6 F).

Reviews of airlines servicing Gainesville

Delta

8.0

Very good

8,511 reviews

Reviews

1 / 10

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Delta

8.0

Very good

8,511 reviews

Delta

8.0

Very good

8,511 reviews

Reviews

1 / 10

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

8,511 reviews

Reviews

1 / 10

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

What are the cheapest airlines flying from Des Moines to Gainesville round-trip?
Flying on Delta is currently your cheapest option to Gainesville, with prices starting at $452. Another option worth looking into is American Airlines, starting at $457 round trip. Delta is priced at 25% lower than the current average price of a flight leaving 3 months from now.
Can I find deals for flights from Des Moines to Gainesville that include hotel bookings?
Yes. In addition to deals on Des Moines to Gainesville flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Des Moines to Gainesville?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Gainesville.
Can I find deals for business class flights from Des Moines to Gainesville?
Yes. Cheapflights offers flight deals from Des Moines to Gainesville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Des Moines to Gainesville?
Currently, January is the cheapest month in which you can book a flight from Des Moines to Gainesville (average of $359). Flying from Des Moines to Gainesville in November is currently the most expensive (average of $510). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Lake City

Alachua

Browse thousands of different options on Cheapflights for your next trip

Top 2 airlines flying from Des Moines to Gainesville

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$366	Average$521	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$410	Average$506	FlexibilityNo cancel fee	On-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.

$254+ Cheap flights from Des Moines to Gainesville (DSM - GNV)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/3. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Des Moines to Gainesville with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Des Moines to Gainesville

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Find flight deals from Des Moines to Gainesville

Cheapest flights from Des Moines to GainesvilleExplore the most affordable flight options available from Des Moines to Gainesville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 16, 2025.

Explore the most affordable flight options available from Des Moines to Gainesville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 16, 2025.

Find flights from Des Moines to Gainesville within your budget

Compare providers for flights from Des Moines to Gainesville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Gainesville in January.

Best time to book a flight from Des Moines to Gainesville

Have a flexible travel schedule? Discover the best time to fly to Gainesville from Des Moines with our price prediction graph.

Travel insights for flights from Des Moines to Gainesville

Get recent, data-driven insights about flights from Des Moines to Gainesville including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Des Moines to Gainesville?

Rainfall in Gainesville by month

Plan your trip to Gainesville by taking into account the average rainfall totals by month.

Temperature in Gainesville by month

Plan your trip to Gainesville by taking into account the average temperature totals by month.

Reviews of airlines servicing Gainesville

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Gainesville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines flying from Des Moines to Gainesville round-trip?

Can I find deals for flights from Des Moines to Gainesville that include hotel bookings?

How can I find direct flights from Des Moines to Gainesville?

Can I find deals for business class flights from Des Moines to Gainesville?

What is the cheapest month to book a flight from Des Moines to Gainesville?

Traveling to a place near Des Moines?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Des Moines to Gainesville

See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from Des Moines to Gainesville

100% Free

Book with Flexibility

Travel Smart

Cheapest flights from Des Moines to Gainesville
Explore the most affordable flight options available from Des Moines to Gainesville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 16, 2025.