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$159+ Cheap flights from Des Moines to Fort Myers (DSM - RSW)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/17. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — RSW
Apr 27 — May 41
Sun 4/27
Sun 5/4
1 adult, Economy
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1. Tell us where you want to go

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Cheapflights Tip: The best prices from Des Moines to Fort Myers SW Florida Intl are usually found in August or May, booked 65 days in advance, depart on a Tuesday or Wednesday and return on a Friday

Cheap flight deals from Des Moines to Fort Myers

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Fort Myers (RSW). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 22, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$285
(Delta)

One-way from

$159
(Delta)

Popular in

April

Cheapest in

August

Average price

$542
Provider with most accurate pricing for Des Moines-Fort Myers SW Florida Intl flight deals.
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Provider most trusted by Cheapflights users for Des Moines-Fort Myers SW Florida Intl flights.
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From Des Moines to Fort Myers SW Florida Intl
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One-way flight from Des Moines to Fort Myers SW Florida Intl
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Highest demand for flights based on searches. 15% potential increase in price ($72 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($13 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from Des Moines to Fort Myers

Cheapest flights from Des Moines to Fort Myers
Explore the most affordable flight options available from Des Moines to Fort Myers. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 22, 2025.

This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/42:15 pmDSM - RSW
1 stop7h 20mDelta
Wed 6/115:40 amRSW - DSM
1 stop5h 59mDelta
Deal found 4/22$285
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/215:32 amDSM - RSW
2 stops9h 59mAmerican Airlines
Wed 5/283:59 pmRSW - DSM
1 stop7h 57mAmerican Airlines
Deal found 4/21$290
This Southwest deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/274:45 pmDSM - RSW
1 stop4h 20mSouthwest
Fri 5/306:55 pmRSW - DSM
1 stop5h 10mSouthwest
Deal found 4/21$301
This Mytrip deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/56:32 pmDSM - RSW
2 stops20h 31mMultiple Airlines
Thu 6/1210:19 amRSW - DSM
2 stops29h 26mMultiple Airlines
Deal found 4/21$318
This United Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2311:16 amDSM - RSW
1 stop8h 01mUnited Airlines
Tue 5/275:03 pmRSW - DSM
1 stop6h 19mUnited Airlines
Deal found 4/21$346

Cheapflights Fare Finder

Customize your flight search to find flights from Des Moines to Fort Myers that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 22, 2025.
Use the filters below to find and compare flights from Des Moines to Fort Myers that are best for you.

Fly from

Des Moines

Fly to

Fort Myers

Route

Depart

Return

Price

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Wed 6/4

2:15 pm-10:35 pm

1 stop7h 20m

Fort Myers SW Florida Intl

Wed 6/11

5:40 am-10:39 am

1 stop5h 59m

$285

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Wed 5/21

5:32 am-4:31 pm

2 stops9h 59m

Fort Myers SW Florida Intl

Wed 5/28

3:59 pm-10:56 pm

1 stop7h 57m

$290

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Tue 5/27

4:45 pm-10:05 pm

1 stop4h 20m

Fort Myers SW Florida Intl

Fri 5/30

6:55 pm-11:05 pm

1 stop5h 10m

$301

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Thu 6/5

6:32 pm-4:03 pm

2 stops20h 31m

Fort Myers SW Florida Intl

Thu 6/12

10:19 am-2:45 pm

2 stops29h 26m

$318

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Fri 5/23

11:16 am-8:17 pm

1 stop8h 01m

Fort Myers SW Florida Intl

Tue 5/27

5:03 pm-10:22 pm

1 stop6h 19m

$346

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Mon 5/26

4:04 pm-10:52 pm

1 stop5h 48m

$160

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Fri 5/23

6:35 pm-12:38 am

1 stop5h 03m

$194

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Thu 5/22

6:00 am-5:35 pm

2 stops10h 35m

$229

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Fri 5/23

1:21 pm-4:03 pm

3 stops25h 42m

$306

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/21

Compare providers for flights from Des Moines to Fort Myers

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Fort Myers in April.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*2 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Fort Myers flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Fort Myers flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Fort Myers flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Fort Myers flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Fort Myers flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Fort Myers

Have a flexible travel schedule? Discover the best time to fly to Fort Myers from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Fort Myers

How far ahead should I book a flight from Des Moines to Fort Myers?

Use this chart to determine the optimal time to book a round-trip flight from Des Moines to Fort Myers. Price data was last updated on April 18, 2025.

The price you pay for your flight from Des Moines to Fort Myers may vary depending on when you book. For the best chance of a lower fare, look to book 65 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Des Moines to Fort Myers?

Currently, January is the cheapest month in which you can book a flight from Des Moines to Fort Myers (average of $205). Flying from Des Moines to Fort Myers in June is currently the most expensive (average of $297). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to RSW?

Find hourly flight availability from Des Moines to Fort Myers. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 22, 2025.

A simple way to save on the total cost of your ticket is to fly from Des Moines to Fort Myers at noon. If you’re flexible enough to do this you can expect to save up to 19% on your trip compared to booking a flight in the morning.

Rainfall in Fort Myers by month

Plan your trip to Fort Myers by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Fort Myers ranges from 1.7 - 10.1 inches per month. June is typically the wettest month, when rainfall can reach 10.1 in. December is typically the driest time to visit Fort Myers when rainfall is around 1.7 in.

Temperature in Fort Myers by month

Plan your trip to Fort Myers by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Fort Myers, use this chart to help with planning. For those seeking warmer temperatures, August is the ideal time of year to visit, when temperatures reach an average of 84.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 64.4 F).

Reviews of airlines servicing Fort Myers

Get insights into the airlines that provide service to Fort Myers. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Fort Myers. Reviews last updated April 22, 2025.
Southwest
8.0
Very good
4,287 reviews

Comfort

8.0

Overall

8.0

Food

7.1

Crew

8.6

Boarding

8.2

Entertainment

7.6

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
Southwest
8.0
Very good
4,287 reviews
Southwest
8.0
Very good
4,287 reviews

Comfort

8.0

Overall

8.0

Food

7.1

Crew

8.6

Boarding

8.2

Entertainment

7.6

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
Delta
8.0
Very good
7,920 reviews
Southwest
8.0
Very good
4,287 reviews

Comfort

8.0

Overall

8.0

Food

7.1

Crew

8.6

Boarding

8.2

Entertainment

7.6

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
United Airlines
7.4
Good
8,683 reviews
Southwest
8.0
Very good
4,287 reviews

Comfort

8.0

Overall

8.0

Food

7.1

Crew

8.6

Boarding

8.2

Entertainment

7.6

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,287 reviews

Comfort

8.0

Overall

8.0

Food

7.1

Crew

8.6

Boarding

8.2

Entertainment

7.6

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Fort Myers. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Des Moines to Fort Myers round-trip?

    Cheapflights users have booked flights from Des Moines to Fort Myers round-trip from $285. Other airlines that can offer you cheap pricing are American Airlines, from $290, and Southwest, from $301. Delta is currently priced 30% below the average price you’ll pay for this route.

  • What are the cheapest airlines to fly from Des Moines to Fort Myers one-way?

    One-way options have recently been found by users for as low as $159 on Delta. Other airlines that offer cheap prices include American Airlines from $160 and Southwest from $229 one-way.

  • Can I find deals for flights from Des Moines to Fort Myers that include hotel bookings?

    Yes. In addition to deals on Des Moines to Fort Myers flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Fort Myers?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Fort Myers.

  • Can I find deals for business class flights from Des Moines to Fort Myers?

    Yes. Cheapflights offers flight deals from Des Moines to Fort Myers by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Fort Myers?

    Currently, January is the cheapest month in which you can book a flight from Des Moines to Fort Myers (average of $205). Flying from Des Moines to Fort Myers in June is currently the most expensive (average of $297). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Sanibel
North Fort Myers
Estero
Lehigh Acres

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Top 5 airlines flying from Des Moines to Fort Myers

Discover the top 5 airlines that operate flights from Des Moines to Fort Myers. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 22, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$107Average$296FlexibilityNo cancel feeOn-time88%
United AirlinesCheapest$276Average$466FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$284Average$385FlexibilityNo cancel feeOn-time71%
DeltaCheapest$285Average$411FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$351Average$466FlexibilityNo cancel feeOn-time63%

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