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Florida Keys

$88+ Cheap flights from St. Louis (STL) to Florida Keys

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/17. Fares are subject to change and may not be available on all flights or dates of travel.
STL — EYW
Apr 22 — Apr 291
Tue 4/22
Tue 4/29
1 adult, Economy
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Cheap flight deals from St. Louis to Florida Keys

Keep the following information in mind while searching for St. Louis to Florida Keys flight deals. Data was last updated April 17, 2025.

Most accurate provider

Mytrip
3 stars

Most trusted provider

Mytrip
3 stars

Round-trip from

$241
(CheapOair)

One-way from

$88
(Cheapflightsfares)

Popular in

March

Cheapest in

September

Average price

$399
Provider with most accurate pricing for Lambert-St Louis-Miami flight deals.
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Provider most trusted by Cheapflights users for Lambert-St Louis-Miami flights.
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From Lambert-St Louis to Florida Keys
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One-way flight from Lambert-St Louis to Florida Keys
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($48 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($13 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from St. Louis to Florida Keys

Cheapest flights from St. Louis to Florida Keys
Explore the most affordable flight options available from St. Louis to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 17, 2025.

This Delta deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/137:05 amSTL - MIA
1 stop5h 10mDelta
Wed 5/2810:37 amMIA - STL
1 stop6h 58mDelta
Deal found 4/17$240
This CheapOair deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/166:53 pmSTL - MIA
1 stop9h 29mFrontier
Sun 5/186:00 amMIA - STL
1 stop28h 09mFrontier
Deal found 4/17$241
This American Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/115:13 amSTL - MIA
Nonstop2h 46mAmerican Airlines
Wed 5/143:30 pmMIA - STL
Nonstop2h 59mAmerican Airlines
Deal found 4/17$243
This American Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/146:00 amSTL - EYW
1 stop6h 39mAmerican Airlines
Wed 5/215:24 pmEYW - STL
1 stop5h 02mAmerican Airlines
Deal found 4/16$251
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2511:51 amSTL - EYW
1 stop6h 53mDelta
Tue 12/22:35 pmEYW - STL
1 stop4h 27mDelta
Deal found 4/16$259
This Mytrip deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/1110:10 amSTL - MIA
2 stops32h 47mSpirit Airlines
Wed 5/1410:29 amMIA - STL
2 stops23h 46mSpirit Airlines
Deal found 4/17$285
This Southwest deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/145:55 pmSTL - MIA
Nonstop2h 40mSouthwest
Mon 5/197:20 amMIA - STL
2 stops9h 30mSouthwest
Deal found 4/16$295
This Mytrip deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/3112:15 pmSTL - MIA
2 stops23h 15mMultiple Airlines
Fri 6/69:05 amMIA - STL
2 stops27h 20mMultiple Airlines
Deal found 4/17$313
This United Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/118:30 amSTL - MIA
1 stop6h 24mUnited Airlines
Wed 5/146:20 amMIA - STL
2 stops9h 27mUnited Airlines
Deal found 4/17$321
This Mytrip deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/108:44 amSTL - EYW
2 stops23h 49mMultiple Airlines
Fri 8/151:47 pmEYW - STL
3 stops43h 02mMultiple Airlines
Deal found 4/17$535
This United Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/208:00 amSTL - EYW
1 stop6h 04mUnited Airlines
Sat 4/268:45 amEYW - STL
2 stops12h 19mUnited Airlines
Deal found 4/17$539

Cheapflights Fare Finder

Customize your flight search to find flights from St. Louis to Florida Keys that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
Use the filters below to find and compare flights from St. Louis to Florida Keys that are best for you.

Fly from

St. Louis

Fly to

Florida Keys

Route

Depart

Return

Price

St. LouisMiami

STL - MIA

STLMIA

Lambert-St Louis

Tue 5/13

7:05 am-1:15 pm

1 stop5h 10m

Miami

Wed 5/28

10:37 am-4:35 pm

1 stop6h 58m

$240

St. LouisMiami

STL - MIA

STLMIA

Lambert-St Louis

Fri 5/16

6:53 pm-5:22 am

1 stop9h 29m

Miami

Sun 5/18

6:00 am-9:09 am

1 stop28h 09m

$241

St. LouisMiami

STL - MIA

STLMIA

Lambert-St Louis

Wed 5/14

10:36 am-6:41 pm

1 stop7h 05m

Miami

Tue 5/20

3:30 pm-5:29 pm

Nonstop2h 59m

$243

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Tue 9/30

5:29 am-1:34 pm

1 stop7h 05m

Key West

Sat 10/4

7:31 pm-11:01 pm

1 stop4h 30m

$251

St. LouisMiami

STL - MIA

STLMIA

Lambert-St Louis

Thu 5/15

10:10 am-10:49 am

2 stops23h 39m

Miami

Thu 5/22

9:05 am-11:25 am

2 stops27h 20m

$283

St. LouisMiami

STL - MIA

STLMIA

Lambert-St Louis

Sun 5/11

10:10 am-7:57 pm

2 stops32h 47m

Miami

Wed 5/14

10:29 am-9:15 am

2 stops23h 46m

$285

St. LouisMiami

STL - MIA

STLMIA

Lambert-St Louis

Tue 5/13

10:15 am-8:55 pm

2 stops9h 40m

Miami

Tue 5/20

3:30 pm-10:10 pm

1 stop7h 40m

$289

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Thu 8/28

1:30 pm-7:46 pm

1 stop5h 16m

Key West

Sun 8/31

7:00 am-12:24 pm

1 stop6h 24m

$314

St. LouisMiami

STL - MIA

STLMIA

Lambert-St Louis

Tue 5/13

6:30 am-4:16 pm

2 stops8h 46m

Miami

Thu 5/22

12:06 pm-4:53 pm

1 stop5h 47m

$331

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Mon 7/14

8:00 am-6:05 pm

2 stops9h 05m

Key West

Mon 7/21

6:45 pm-10:45 pm

2 stops29h 00m

$533

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/17

Showing 1-10 of 20 results
1
2

Best time to book a flight from St. Louis to Florida Keys

Have a flexible travel schedule? Discover the best time to fly to Florida Keys from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Florida Keys

What is the cheapest month to book a flight from St. Louis to Florida Keys?

Currently, August is the cheapest month in which you can book a flight from St. Louis to Florida Keys (average of $328). Flying from St. Louis to Florida Keys in March is currently the most expensive (average of $493). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Rainfall in Florida Keys by month

Plan your trip to Florida Keys by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Florida Keys ranges from 1.6 - 9.9 inches per month. September is typically the wettest month, when rainfall can reach 9.9 in. January is typically the driest time to visit Florida Keys when rainfall is around 1.6 in.

Temperature in Florida Keys by month

Plan your trip to Florida Keys by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Florida Keys, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 84.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 68.0 F).

Reviews of airlines servicing Florida Keys

Get insights into the airlines that provide service to Florida Keys. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florida Keys. Reviews last updated April 17, 2025.
Get a feel of what it's like to fly with Southwest, Delta and United Airlines from St. Louis to Florida Keys by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,280 reviews

Boarding

8.2

Overall

8.0

Food

7.1

Crew

8.6

Comfort

8.0

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Southwest
8.0
Very good
4,280 reviews
Southwest
8.0
Very good
4,280 reviews

Boarding

8.2

Overall

8.0

Food

7.1

Crew

8.6

Comfort

8.0

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Delta
8.0
Very good
7,917 reviews
Southwest
8.0
Very good
4,280 reviews

Boarding

8.2

Overall

8.0

Food

7.1

Crew

8.6

Comfort

8.0

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
United Airlines
7.4
Good
8,667 reviews
Southwest
8.0
Very good
4,280 reviews

Boarding

8.2

Overall

8.0

Food

7.1

Crew

8.6

Comfort

8.0

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,280 reviews

Boarding

8.2

Overall

8.0

Food

7.1

Crew

8.6

Comfort

8.0

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Spirit Airlines
6.3
Okay
7,926 reviews
Southwest
8.0
Very good
4,280 reviews

Boarding

8.2

Overall

8.0

Food

7.1

Crew

8.6

Comfort

8.0

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Florida Keys. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from St. Louis to Florida Keys?

    Located just 12.7 mi from the city center, Lambert-St Louis (STL) is the airport most travelers will use when flying to Florida Keys from St. Louis.

  • What are the cheapest airlines to fly from St. Louis to Florida Keys one-way?

    The cheapest airlines for a one-way flight from St. Louis to Florida Keys are Frontier ($88), American Airlines ($90), and Delta ($100).

  • Can I find deals for flights from St. Louis to Florida Keys that include hotel bookings?

    Yes. In addition to deals on St. Louis to Florida Keys flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Florida Keys?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Florida Keys.

  • Can I find deals for business class flights from St. Louis to Florida Keys?

    Yes. Cheapflights offers flight deals from St. Louis to Florida Keys by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from St. Louis to Florida Keys?

    Currently, August is the cheapest month in which you can book a flight from St. Louis to Florida Keys (average of $328). Flying from St. Louis to Florida Keys in March is currently the most expensive (average of $493). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for St. Louis to Florida Keys

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from St. Louis to Florida Keys

Discover the top 3 airlines that operate flights from St. Louis to Florida Keys. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$219Average$434FlexibilityNo cancel feeOn-time71%
DeltaCheapest$228Average$470FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$268Average$557FlexibilityNo cancel feeOn-time69%

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