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$55+ Cheap flights from St. Louis (STL) to Florida Keys

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/7. Fares are subject to change and may not be available on all flights or dates of travel.
STL — EYW
Feb 4 — Feb 111
Tue 2/4
Tue 2/11
1 adult, Economy
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Cheap flight deals from St. Louis to Florida Keys

Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Florida Keys (zzEOA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 30, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$279
(American Airlines)

One-way from

$55
(Frontier)

Popular in

March

Cheapest in

September

Average price

$389
Provider with most accurate pricing for Lambert-St Louis-Miami flight deals.
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Provider most trusted by Cheapflights users for Lambert-St Louis-Miami flights.
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From Lambert-St Louis to Florida Keys
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One-way flight from Lambert-St Louis to Florida Keys
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Highest demand for flights based on searches. 8% potential increase in price ($35 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($11 potential savings vs. average RT price).
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Average for round-trip flights in January 2025
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Find flight deals from St. Louis to Florida Keys

Cheapest flights from St. Louis to Florida Keys
Explore the most affordable flight options available from St. Louis to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 30, 2025.

This American Airlines deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/67:30 amSTL - EYW
1 stop7h 31mAmerican Airlines
Sat 9/138:14 amEYW - STL
1 stop8h 09mAmerican Airlines
Deal found 1/30$259
This Trip.com deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/235:20 pmSTL - EYW
1 stop15h 50mMultiple Airlines
Thu 2/273:05 pmEYW - STL
1 stop9h 39mMultiple Airlines
Deal found 1/29$288
This Delta deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/206:06 amSTL - MIA
1 stop11h 48mDelta
Wed 2/267:00 amMIA - STL
1 stop5h 46mDelta
Deal found 1/29$295
This Southwest deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/196:40 pmSTL - MIA
Nonstop2h 40mSouthwest
Wed 4/238:30 amMIA - STL
2 stops10h 15mSouthwest
Deal found 1/29$297
This Delta deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/47:15 amSTL - EYW
1 stop5h 53mDelta
Sat 3/86:14 pmEYW - STL
1 stop6h 22mDelta
Deal found 1/28$298
This Mytrip deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/274:00 pmSTL - MIA
2 stops30h 29mMultiple Airlines
Thu 3/69:53 pmMIA - STL
3 stops19h 52mMultiple Airlines
Deal found 1/29$299
This Booking.com deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/147:09 pmSTL - MIA
1 stop9h 07mFrontier
Tue 2/186:25 amMIA - STL
1 stop27h 51mFrontier
Deal found 1/30$300
This American Airlines deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/275:13 amSTL - MIA
Nonstop2h 56mAmerican Airlines
Thu 3/69:50 pmMIA - STL
Nonstop2h 56mAmerican Airlines
Deal found 1/29$301
This Mytrip deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/95:38 pmSTL - MIA
2 stops26h 20mSpirit Airlines
Fri 3/142:32 pmMIA - STL
2 stops19h 37mSpirit Airlines
Deal found 1/29$316
This United Airlines deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/18:40 amSTL - MIA
1 stop8h 14mUnited Airlines
Wed 3/126:00 amMIA - STL
2 stops10h 31mUnited Airlines
Deal found 1/29$387
This United Airlines deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/18:40 amSTL - EYW
1 stop6h 29mUnited Airlines
Sat 3/84:50 pmEYW - STL
1 stop6h 17mUnited Airlines
Deal found 1/29$454

Find flights from St. Louis to Florida Keys within your budget

Customize your flight search to find flights from St. Louis to Florida Keys that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 30, 2025.

Fly from

Any airport

Fly to

Any airport

Route

Depart

Return

Price

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Tue 4/15

9:52 am-6:55 pm

2 stops8h 03m

Key West

Wed 4/30

11:39 am-5:37 pm

1 stop6h 58m

$274

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Sun 2/23

5:20 pm-10:10 am

1 stop15h 50m

Key West

Thu 2/27

3:05 pm-11:44 pm

1 stop9h 39m

$288

St. LouisMiami

STL - MIA

STLMIA

Lambert-St Louis

Sat 4/12

1:48 pm-8:47 pm

1 stop5h 59m

Miami

Thu 4/17

8:16 pm-10:21 pm

Nonstop3h 05m

$292

St. LouisMiami

STL - MIA

STLMIA

Lambert-St Louis

Thu 2/20

6:06 am-6:54 pm

1 stop11h 48m

Miami

Wed 2/26

7:00 am-11:46 am

1 stop5h 46m

$295

St. LouisMiami

STL - MIA

STLMIA

Lambert-St Louis

Sat 4/19

6:40 pm-10:20 pm

Nonstop2h 40m

Miami

Wed 4/23

8:30 am-5:45 pm

2 stops10h 15m

$297

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Tue 3/4

7:15 am-2:08 pm

1 stop5h 53m

Key West

Sat 3/8

6:14 pm-11:36 pm

1 stop6h 22m

$298

St. LouisMiami

STL - MIA

STLMIA

Lambert-St Louis

Thu 2/27

4:00 pm-11:29 pm

2 stops30h 29m

Miami

Thu 3/6

9:53 pm-4:45 pm

3 stops19h 52m

$299

St. LouisMiami

STL - MIA

STLMIA

Lambert-St Louis

Fri 2/14

7:09 pm-5:16 am

1 stop9h 07m

Miami

Tue 2/18

6:25 am-9:16 am

1 stop27h 51m

$300

St. LouisMiami

STL - MIA

STLMIA

Lambert-St Louis

Sun 3/9

5:38 pm-8:58 pm

2 stops26h 20m

Miami

Fri 3/14

2:32 pm-9:09 am

2 stops19h 37m

$316

St. LouisMiami

STL - MIA

STLMIA

Lambert-St Louis

Sat 3/1

10:55 am-5:54 pm

1 stop5h 59m

Miami

Thu 3/6

6:00 am-3:31 pm

2 stops10h 31m

$387

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/30

Showing 1-10 of 22 results
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Best time to book a flight from St. Louis to Florida Keys

Have a flexible travel schedule? Discover the best time to fly to Florida Keys from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from St. Louis to Florida Keys

Get recent, data-driven insights about flights from St. Louis to Florida Keys including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from St. Louis to Florida Keys?

Currently, August is the cheapest month in which you can book a flight from St. Louis to Florida Keys (average of $328). Flying from St. Louis to Florida Keys in March is currently the most expensive (average of $526). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Rainfall in Florida Keys by month

Plan your trip to Florida Keys by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Florida Keys ranges from 1.6 - 9.9 inches per month. September is typically the wettest month, when rainfall can reach 9.9 in. January is typically the driest time to visit Florida Keys when rainfall is around 1.6 in.

Temperature in Florida Keys by month

Plan your trip to Florida Keys by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Florida Keys, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 84.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 68.0 F).

Reviews of airlines servicing Florida Keys

Get insights into the airlines that provide service to Florida Keys. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florida Keys. Reviews last updated January 30, 2025.
Get a feel of what it's like to fly with Southwest, Delta and United Airlines from St. Louis to Florida Keys by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
4,585 reviews

Overall

8.1

Crew

8.7

Boarding

8.2

Entertainment

7.7

Food

7.1

Comfort

8.1

Reviews

1 / 20

6.0
Good

Lauren,Dec 2024

MCI - DCA

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Southwest
8.1
Very good
4,585 reviews
Southwest
8.1
Very good
4,585 reviews

Overall

8.1

Crew

8.7

Boarding

8.2

Entertainment

7.7

Food

7.1

Comfort

8.1

Reviews

1 / 20

6.0
Good

Lauren,Dec 2024

MCI - DCA

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Delta
8.0
Very good
8,454 reviews
Southwest
8.1
Very good
4,585 reviews

Overall

8.1

Crew

8.7

Boarding

8.2

Entertainment

7.7

Food

7.1

Comfort

8.1

Reviews

1 / 20

6.0
Good

Lauren,Dec 2024

MCI - DCA

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

United Airlines
7.4
Good
8,913 reviews
Southwest
8.1
Very good
4,585 reviews

Overall

8.1

Crew

8.7

Boarding

8.2

Entertainment

7.7

Food

7.1

Comfort

8.1

Reviews

1 / 20

6.0
Good

Lauren,Dec 2024

MCI - DCA

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

American Airlines
7.2
Good
10,000 reviews
Southwest
8.1
Very good
4,585 reviews

Overall

8.1

Crew

8.7

Boarding

8.2

Entertainment

7.7

Food

7.1

Comfort

8.1

Reviews

1 / 20

6.0
Good

Lauren,Dec 2024

MCI - DCA

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Sun Country Air
7.0
Good
386 reviews
Southwest
8.1
Very good
4,585 reviews

Overall

8.1

Crew

8.7

Boarding

8.2

Entertainment

7.7

Food

7.1

Comfort

8.1

Reviews

1 / 20

6.0
Good

Lauren,Dec 2024

MCI - DCA

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Florida Keys. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from St. Louis to Florida Keys?

    Located just 12.7 mi from the city center, Lambert-St Louis (STL) is the airport most travelers will use when flying to Florida Keys from St. Louis.

  • What are the cheapest airlines to fly from St. Louis to Florida Keys one-way?

    The cheapest airlines for a one-way flight from St. Louis to Florida Keys are Frontier ($55), Spirit Airlines ($81), and American Airlines ($100).

  • Can I find deals for flights from St. Louis to Florida Keys that include hotel bookings?

    Yes. In addition to deals on St. Louis to Florida Keys flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Florida Keys?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Florida Keys.

  • Can I find deals for business class flights from St. Louis to Florida Keys?

    Yes. Cheapflights offers flight deals from St. Louis to Florida Keys by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from St. Louis to Florida Keys?

    Currently, August is the cheapest month in which you can book a flight from St. Louis to Florida Keys (average of $328). Flying from St. Louis to Florida Keys in March is currently the most expensive (average of $526). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for St. Louis to Florida Keys

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from St. Louis to Florida Keys

Discover the top 3 airlines that operate flights from St. Louis to Florida Keys. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$237Average$443FlexibilityNo cancel feeOn-time71%
DeltaCheapest$257Average$484FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$287Average$577FlexibilityNo cancel feeOn-time69%
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