$42+ Cheap flights from South Carolina to Florida Keys
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/9. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — EYW
abr. 9 — abr. 161
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from South Carolina to Florida Keys with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from South Carolina to Florida Keys
Keep the following information in mind while searching for South Carolina to Florida Keys flight deals. Data was last updated abril 4, 2025.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $77 (Cheapflightsfares) |
One-way from | $42 (FlightHub) |
Popular in | February |
Cheapest in | June |
Average price | $263 |
Find flight deals from South Carolina to Florida Keys
Cheapest flights from South Carolina to Florida KeysExplore the most affordable flight options available from South Carolina to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on abril 4, 2025.
Explore the most affordable flight options available from South Carolina to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on abril 4, 2025.
This Cheapflightsfares deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 4/2810:19 pmCLT - MIA
Nonstop2h 03mSpirit Airlines
vie. 5/21:13 pmMIA - CLT
Nonstop2h 12mSpirit Airlines
Deal found 4/2![Spirit Airlines logo]()
$77
This FlightHub deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 4/3010:19 pmCLT - MIA
Nonstop2h 03mMultiple Airlines
jue. 5/16:00 amMIA - CLT
Nonstop2h 14mMultiple Airlines
Deal found 4/3![Multiple Airlines logo]()
$80
This Cheapflightsfares deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 4/208:53 amCLT - MIA
Nonstop2h 10mFrontier
jue. 4/249:15 amMIA - CLT
Nonstop2h 18mFrontier
Deal found 4/3![Frontier logo]()
$106
This Cheapflightsfares deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 5/211:06 amMYR - MIA
1 stop6h 57mSpirit Airlines
dom. 5/45:45 amMIA - MYR
1 stop10h 13mSpirit Airlines
Deal found 4/3![Spirit Airlines logo]()
$152
This CheapOair deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 5/1011:52 amMYR - MIA
1 stop11h 34mFrontier
dom. 5/186:00 amMIA - MYR
1 stop8h 09mFrontier
Deal found 4/3![Frontier logo]()
$160
This Kiwi.com deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 6/282:48 pmCHS - EYW
1 stop18h 34mBreeze Airways
vie. 7/41:47 pmEYW - CHS
1 stop19h 27mBreeze Airways
Deal found 4/3![Breeze Airways logo]()
$179
This Delta deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 5/127:55 pmMYR - MIA
1 stop4h 42mDelta
vie. 5/165:35 amMIA - MYR
1 stop4h 33mDelta
Deal found 4/2![Delta logo]()
$201
This Mytrip deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 5/110:25 amCHS - MIA
2 stops34h 06mSpirit Airlines
dom. 5/410:51 pmMIA - CHS
2 stops18h 15mSpirit Airlines
Deal found 4/3![Spirit Airlines logo]()
$214
This American Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 5/217:10 pmCHS - MIA
Nonstop1h 45mAmerican Airlines
jue. 5/228:09 amMIA - CHS
Nonstop1h 43mAmerican Airlines
Deal found 4/4![American Airlines logo]()
$217
This Frontier deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 4/73:39 pmCHS - MIA
1 stop8h 56mFrontier
sáb. 4/1210:11 amMIA - CHS
1 stop9h 15mFrontier
Deal found 4/3![Frontier logo]()
$220
This Delta deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 6/176:17 pmCHS - MIA
1 stop6h 36mDelta
mar. 6/245:35 amMIA - CHS
1 stop4h 04mDelta
Deal found 4/4![Delta logo]()
$239
This American Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 7/126:46 amCAE - MIA
Nonstop1h 53mAmerican Airlines
sáb. 7/196:17 amMIA - CAE
1 stop4h 30mAmerican Airlines
Deal found 4/3![American Airlines logo]()
$241
Cheapflights Fare Finder
Customize your flight search to find flights from South Carolina to Florida Keys that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated abril 4, 2025.
Use the filters below to find and compare flights from South Carolina to Florida Keys that are best for you.
Fly from
South Carolina
Fly to
Florida Keys
Route
Depart
Return
Price
CharlotteMiami
CLT - MIA
CLTMIA
Charlotte Douglas
lun. 4/28
10:19 pm-12:22 am
Nonstop2h 03m
Miami
vie. 5/2
1:13 pm-3:25 pm
Nonstop2h 12m
$77
CharlotteMiami
CLT - MIA
CLTMIA
Charlotte Douglas
mié. 4/30
10:19 pm-12:22 am
Nonstop2h 03m
Miami
jue. 5/1
6:00 am-8:14 am
Nonstop2h 14m
$80
CharlotteMiami
CLT - MIA
CLTMIA
Charlotte Douglas
dom. 4/20
8:53 am-11:03 am
Nonstop2h 10m
Miami
jue. 4/24
9:15 am-11:33 am
Nonstop2h 18m
$106
Myrtle BeachMiami
MYR - MIA
MYRMIA
Myrtle Beach Intl
vie. 5/2
11:06 am-6:03 pm
1 stop6h 57m
Miami
dom. 5/4
5:45 am-3:58 pm
1 stop10h 13m
$152
Myrtle BeachMiami
MYR - MIA
MYRMIA
Myrtle Beach Intl
sáb. 5/10
11:52 am-11:26 pm
1 stop11h 34m
Miami
dom. 5/18
6:00 am-2:09 pm
1 stop8h 09m
$160
CharlestonKey West
CHS - EYW
CHSEYW
Charleston
sáb. 6/28
2:48 pm-9:22 am
1 stop18h 34m
Key West
vie. 7/4
1:47 pm-9:14 am
1 stop19h 27m
$179
Myrtle BeachMiami
MYR - MIA
MYRMIA
Myrtle Beach Intl
lun. 5/12
7:55 pm-12:37 am
1 stop4h 42m
Miami
vie. 5/16
5:35 am-10:08 am
1 stop4h 33m
$201
CharlestonMiami
CHS - MIA
CHSMIA
Charleston
jue. 5/1
10:25 am-8:31 pm
2 stops34h 06m
Miami
dom. 5/4
10:51 pm-5:06 pm
2 stops18h 15m
$214
CharlestonMiami
CHS - MIA
CHSMIA
Charleston
mié. 5/21
7:10 pm-8:55 pm
Nonstop1h 45m
Miami
jue. 5/22
8:09 am-9:52 am
Nonstop1h 43m
$217
CharlestonMiami
CHS - MIA
CHSMIA
Charleston
mar. 6/17
6:17 pm-12:53 am
1 stop6h 36m
Miami
mar. 6/24
5:35 am-9:39 am
1 stop4h 04m
$239
Showing 1-10 of 60 results
Best time to book a flight from South Carolina to Florida Keys
Have a flexible travel schedule? Discover the best time to fly to Florida Keys from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from South Carolina to Florida Keys
What is the cheapest month to book a flight from South Carolina to Florida Keys?
Currently, August is the cheapest month in which you can book a flight from South Carolina to Florida Keys (average of $328). Flying from South Carolina to Florida Keys in March is currently the most expensive (average of $493). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from SC to EOA?
Find hourly flight availability from South Carolina to Florida Keys. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated abril 4, 2025.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from South Carolina to Florida Keys as you normally would.
Rainfall in Florida Keys by month
Plan your trip to Florida Keys by taking into account the average rainfall totals by month.
In terms of precipitation, rainfall in Florida Keys ranges from 1.6 - 9.9 inches per month. September is typically the wettest month, when rainfall can reach 9.9 in. January is typically the driest time to visit Florida Keys when rainfall is around 1.6 in.
Temperature in Florida Keys by month
Plan your trip to Florida Keys by taking into account the average temperature totals by month.
If weather is an important factor for your trip to Florida Keys, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 84.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 68.0 F).
Reviews of airlines servicing Florida Keys
Get insights into the airlines that provide service to Florida Keys. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florida Keys. Reviews last updated abril 4, 2025.
Peruse reviews from past customers who have flown with Breeze Airways, Alaska Airlines and Southwest from South Carolina to Florida Keys to help guide your decision. In addition to providing an overall rating, users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.3
Crew
8.8
Entertainment
6.6
Overall
8.1
Comfort
8.2
Food
6.7
Reviews
1 / 11
10.0
ExcellentDena,Dec 2024
LAS - BDL
Boarding
8.3
Crew
8.8
Entertainment
6.6
Overall
8.1
Comfort
8.2
Food
6.7
Reviews
1 / 11
10.0
ExcellentDena,Dec 2024
LAS - BDL
Boarding
8.3
Crew
8.8
Entertainment
6.6
Overall
8.1
Comfort
8.2
Food
6.7
Reviews
1 / 11
10.0
ExcellentDena,Dec 2024
LAS - BDL
Boarding
8.3
Crew
8.8
Entertainment
6.6
Overall
8.1
Comfort
8.2
Food
6.7
Reviews
1 / 11
10.0
ExcellentDena,Dec 2024
LAS - BDL
Boarding
8.3
Crew
8.8
Entertainment
6.6
Overall
8.1
Comfort
8.2
Food
6.7
Reviews
1 / 11
10.0
ExcellentDena,Dec 2024
LAS - BDL
Boarding
8.3
Crew
8.8
Entertainment
6.6
Overall
8.1
Comfort
8.2
Food
6.7
Reviews
1 / 11
10.0
ExcellentDena,Dec 2024
LAS - BDL
Related info for your journey
Find useful and relevant information for your journey from South Carolina to Florida Keys. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes for South Carolina to Florida Keys
See prices for flight routes from nearby airports that may be better suited for you.
Top 2 airlines flying from South Carolina to Florida Keys
Discover the top 2 airlines that operate flights from South Carolina to Florida Keys. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated abril 4, 2025.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$198 | Average$441 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$246 | Average$488 | FlexibilityNo cancel fee | On-time71% |