Florida Keys

$42+ Cheap flights from South Carolina to Florida Keys

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/5. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — EYW
Jan 26 — Feb 21
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Cheap flight deals from South Carolina to Florida Keys

Discover tips and strategies to find the most affordable flight options for your journey from South Carolina (USSC) to Florida Keys (zzEOA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 21, 2025.

Round-trip from

$79
(Kiwi.com)

One-way from

$43
(Cheapflightsfares)
From South Carolina to Florida Keys
One-way flight from South Carolina to Florida Keys

Find flight deals from South Carolina to Florida Keys

Cheapest flights from South Carolina to Florida Keys
Explore the most affordable flight options available from South Carolina to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 21, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/237:17 amCLT - MIA
1 stop10h 58mSpirit Airlines
Thu 2/279:48 amMIA - CLT
Nonstop2h 12mSpirit Airlines
Deal found 1/19$83
This Frontier deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/205:21 pmCLT - MIA
Nonstop2h 15mFrontier
Tue 2/259:30 amMIA - CLT
1 stop10h 29mFrontier
Deal found 1/21$84
This Cheapflightsfares deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/311:41 pmCLT - MIA
Nonstop2h 15mMultiple Airlines
Sun 2/99:31 amMIA - CLT
Nonstop2h 10mMultiple Airlines
Deal found 1/20$89
This Cheapflightsfares deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/43:56 pmMYR - MIA
1 stop7h 33mSpirit Airlines
Wed 2/126:15 amMIA - MYR
1 stop5h 45mSpirit Airlines
Deal found 1/19$139
This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/117:45 amGSP - EYW
1 stop4h 32mAmerican Airlines
Sat 2/157:29 pmEYW - GSP
1 stop5h 01mAmerican Airlines
Deal found 1/20$199
This Delta deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/185:35 amCAE - MIA
1 stop3h 48mDelta
Tue 2/256:00 amMIA - CAE
1 stop5h 39mDelta
Deal found 1/20$199
This CheapOair deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/251:03 pmCHS - MIA
1 stop19h 50mSpirit Airlines
Mon 3/36:15 amMIA - CHS
1 stop28h 55mSpirit Airlines
Deal found 1/20$201
This JetBlue Airways deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/42:19 pmSAV - MIA
1 stop9h 48mJetBlue
Tue 3/117:00 amMIA - SAV
1 stop6h 24mJetBlue
Deal found 1/21$209
This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/187:30 pmCLT - MIA
Nonstop2h 07mAmerican Airlines
Tue 2/256:00 amMIA - CLT
Nonstop2h 16mAmerican Airlines
Deal found 1/20$209
This Mytrip deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/67:15 amCHS - MIA
2 stops25h 40mMultiple Airlines
Tue 2/113:55 pmMIA - CHS
2 stops19h 25mMultiple Airlines
Deal found 1/20$211
This Delta deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/116:40 amCHS - MIA
1 stop4h 13mDelta
Wed 2/196:00 amMIA - CHS
1 stop5h 25mDelta
Deal found 1/20$217
This Delta deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/112:38 pmSAV - MIA
1 stop4h 25mDelta
Wed 2/127:00 amMIA - SAV
1 stop6h 43mDelta
Deal found 1/21$217

Find flights from South Carolina to Florida Keys within your budget

Customize your flight search to find flights from South Carolina to Florida Keys that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2025.

Fly from

Any airport

Fly to

Any airport

Route

Depart

Return

Price

CharlotteMiami

CLT - MIA

CLTMIA

Charlotte Douglas

Thu 2/20

5:21 pm-7:36 pm

Nonstop2h 15m

Miami

Sat 3/8

9:24 am-11:39 am

Nonstop2h 15m

$79

CharlotteMiami

CLT - MIA

CLTMIA

Charlotte Douglas

Sun 2/23

12:55 pm-2:58 pm

Nonstop2h 03m

Miami

Sat 3/8

9:24 am-11:39 am

Nonstop2h 15m

$81

CharlotteMiami

CLT - MIA

CLTMIA

Charlotte Douglas

Thu 2/20

5:21 pm-7:36 pm

Nonstop2h 15m

Miami

Wed 2/26

8:00 am-6:46 pm

1 stop10h 46m

$84

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Tue 2/4

3:56 pm-11:29 pm

1 stop7h 33m

Miami

Wed 2/12

6:15 am-12:00 pm

1 stop5h 45m

$139

GreenvilleKey West

GSP - EYW

GSPEYW

Greenville

Tue 2/11

7:45 am-12:17 pm

1 stop4h 32m

Key West

Sat 2/15

7:29 pm-12:30 am

1 stop5h 01m

$199

ColumbiaMiami

CAE - MIA

CAEMIA

Columbia Metropolitan

Tue 2/18

5:35 am-9:23 am

1 stop3h 48m

Miami

Tue 2/25

6:00 am-11:39 am

1 stop5h 39m

$199

CharlestonMiami

CHS - MIA

CHSMIA

Charleston

Tue 2/25

1:03 pm-8:53 am

1 stop19h 50m

Miami

Mon 3/3

6:15 am-11:10 am

1 stop28h 55m

$201

SavannahMiami

SAV - MIA

SAVMIA

Savannah/Hilton Head

Tue 3/4

2:19 pm-12:07 am

1 stop9h 48m

Miami

Tue 3/11

7:00 am-1:24 pm

1 stop6h 24m

$209

CharlestonMiami

CHS - MIA

CHSMIA

Charleston

Thu 2/6

7:15 am-8:55 am

2 stops25h 40m

Miami

Tue 2/11

3:55 pm-11:20 am

2 stops19h 25m

$211

CharlestonMiami

CHS - MIA

CHSMIA

Charleston

Tue 2/11

6:40 am-10:53 am

1 stop4h 13m

Miami

Wed 2/19

6:00 am-11:25 am

1 stop5h 25m

$217

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/21

Showing 1-10 of 60 results
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Best time to book a flight from South Carolina to Florida Keys

Have a flexible travel schedule? Discover the best time to fly to Florida Keys from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from South Carolina to Florida Keys

Get recent, data-driven insights about flights from South Carolina to Florida Keys including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from South Carolina to Florida Keys?

Currently, August is the cheapest month in which you can book a flight from South Carolina to Florida Keys (average of $328). Flying from South Carolina to Florida Keys in March is currently the most expensive (average of $531). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to EOA?

Find hourly flight availability from South Carolina to Florida Keys. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 21, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from South Carolina to Florida Keys as you normally would.

Rainfall in Florida Keys by month

Plan your trip to Florida Keys by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Florida Keys ranges from 1.6 - 9.9 inches per month. September is typically the wettest month, when rainfall can reach 9.9 in. January is typically the driest time to visit Florida Keys when rainfall is around 1.6 in.

Temperature in Florida Keys by month

Plan your trip to Florida Keys by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Florida Keys, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 84.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 68.0 F).

Reviews of airlines servicing Florida Keys

Get insights into the airlines that provide service to Florida Keys. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florida Keys. Reviews last updated January 21, 2025.
Peruse reviews from past customers who have flown with Spirit Airlines, Frontier and JetBlue from South Carolina to Florida Keys to help guide your decision. In addition to providing an overall rating, users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
8.1
Very good
4,662 reviews

Comfort

8.1

Crew

8.7

Food

7.2

Boarding

8.2

Entertainment

7.7

Overall

8.1

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

8.1
Very good
4,662 reviews
8.1
Very good
4,662 reviews

Comfort

8.1

Crew

8.7

Food

7.2

Boarding

8.2

Entertainment

7.7

Overall

8.1

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

8.0
Very good
8,521 reviews
8.1
Very good
4,662 reviews

Comfort

8.1

Crew

8.7

Food

7.2

Boarding

8.2

Entertainment

7.7

Overall

8.1

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

7.4
Good
3,201 reviews
8.1
Very good
4,662 reviews

Comfort

8.1

Crew

8.7

Food

7.2

Boarding

8.2

Entertainment

7.7

Overall

8.1

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

7.4
Good
8,985 reviews
8.1
Very good
4,662 reviews

Comfort

8.1

Crew

8.7

Food

7.2

Boarding

8.2

Entertainment

7.7

Overall

8.1

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

7.2
Good
10,000 reviews
8.1
Very good
4,662 reviews

Comfort

8.1

Crew

8.7

Food

7.2

Boarding

8.2

Entertainment

7.7

Overall

8.1

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Florida Keys. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What are the cheapest airlines to fly from South Carolina to Florida Keys one-way?

    One-way options have recently been found by users for as low as $43 on Spirit Airlines. Other airlines that offer cheap prices include Frontier from $44 and JetBlue from $100 one-way.

  • Can I find deals for flights from South Carolina to Florida Keys that include hotel bookings?

    Yes. In addition to deals on South Carolina to Florida Keys flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Florida Keys?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Florida Keys.

  • Can I find deals for business class flights from South Carolina to Florida Keys?

    Yes. Cheapflights offers flight deals from South Carolina to Florida Keys by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Florida Keys?

    Currently, August is the cheapest month in which you can book a flight from South Carolina to Florida Keys (average of $328). Flying from South Carolina to Florida Keys in March is currently the most expensive (average of $531). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for South Carolina to Florida Keys

See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from South Carolina to Florida Keys

Discover the top 2 airlines that operate flights from South Carolina to Florida Keys. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$198Average$456FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$245Average$498FlexibilityNo cancel feeOn-time71%
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