$129+ Cheap flights from San Diego (SAN) to Florida Keys
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/9. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — EYW
abr. 22 — abr. 291
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Diego to Florida Keys
Keep the following information in mind while searching for San Diego to Florida Keys flight deals. Data was last updated abril 17, 2025.
Most accurate provider | Mytrip 3 stars |
|---|---|
Most trusted provider | Mytrip 3 stars |
Round-trip from | $251 (American Airlines) |
One-way from | $129 (Delta) |
Popular in | December |
Cheapest in | September |
Average price | $409 |
Find flight deals from San Diego to Florida Keys
Cheapest flights from San Diego to Florida KeysExplore the most affordable flight options available from San Diego to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on abril 17, 2025.
Explore the most affordable flight options available from San Diego to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on abril 17, 2025.
This CheapOair deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 4/288:50 pmSAN - MIA
1 stop29h 31mFrontier
jue. 5/16:00 amMIA - SAN
1 stop30h 38mFrontier
Deal found 4/16![Frontier logo]()
$208
This American Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 8/1610:46 pmSAN - EYW
1 stop9h 34mAmerican Airlines
sáb. 8/233:03 pmEYW - SAN
1 stop10h 04mAmerican Airlines
Deal found 4/17![American Airlines logo]()
$251
This Kiwi.com deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 6/76:58 pmSAN - MIA
1 stop7h 45mSpirit Airlines
jue. 6/128:55 pmMIA - SAN
1 stop13h 18mSpirit Airlines
Deal found 4/16![Spirit Airlines logo]()
$269
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 5/166:58 pmSAN - MIA
1 stop7h 45mMultiple Airlines
lun. 5/267:10 amMIA - SAN
1 stop7h 46mMultiple Airlines
Deal found 4/17![Multiple Airlines logo]()
$276
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 6/710:30 pmSAN - MIA
1 stop9h 27mDelta
vie. 6/135:30 amMIA - SAN
1 stop7h 09mDelta
Deal found 4/16![Delta logo]()
$277
This American Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 4/2312:24 pmSAN - MIA
Nonstop4h 49mAmerican Airlines
mar. 4/297:54 pmMIA - SAN
Nonstop5h 44mAmerican Airlines
Deal found 4/15![American Airlines logo]()
$287
This United Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 5/147:10 amSAN - MIA
2 stops10h 24mUnited Airlines
mié. 5/216:20 amMIA - SAN
1 stop7h 43mUnited Airlines
Deal found 4/17![United Airlines logo]()
$303
This Southwest deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 4/229:35 amSAN - MIA
1 stop8h 55mSouthwest
mié. 4/232:40 pmMIA - SAN
2 stops10h 25mSouthwest
Deal found 4/16![Southwest logo]()
$317
This Mytrip deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 5/186:15 amSAN - EYW
2 stops31h 26mMultiple Airlines
dom. 5/258:53 amEYW - SAN
2 stops34h 26mMultiple Airlines
Deal found 4/16![Multiple Airlines logo]()
$377
This United Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 5/3110:20 pmSAN - EYW
1 stop11h 33mUnited Airlines
lun. 6/26:45 pmEYW - SAN
2 stops28h 41mUnited Airlines
Deal found 4/16![United Airlines logo]()
$396
This Delta deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 5/159:45 pmSAN - EYW
1 stop10h 06mDelta
jue. 5/221:51 pmEYW - SAN
1 stop9h 17mDelta
Deal found 4/15![Delta logo]()
$439
This Alaska Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 4/2410:52 amSAN - EYW
3 stops21h 49mAlaska Airlines
mar. 4/2912:16 pmEYW - SAN
3 stops24h 12mAlaska Airlines
Deal found 4/16![Alaska Airlines logo]()
$1,202
Cheapflights Fare Finder
Customize your flight search to find flights from San Diego to Florida Keys that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated abril 17, 2025.
Use the filters below to find and compare flights from San Diego to Florida Keys that are best for you.
Fly from
San Diego
Fly to
Florida Keys
Route
Depart
Return
Price
San DiegoKey West
SAN - EYW
SANEYW
San Diego
sáb. 5/10
10:25 pm-10:50 am
1 stop9h 25m
Key West
mar. 5/13
5:30 pm-11:43 pm
2 stops9h 13m
$256
San DiegoMiami
SAN - MIA
SANMIA
San Diego
jue. 5/15
11:55 am-10:07 pm
1 stop7h 12m
Miami
vie. 5/23
7:10 am-6:26 pm
1 stop14h 16m
$270
San DiegoMiami
SAN - MIA
SANMIA
San Diego
mar. 5/20
8:48 pm-6:45 pm
2 stops18h 57m
Miami
mié. 5/28
10:29 am-11:56 pm
2 stops16h 27m
$272
San DiegoMiami
SAN - MIA
SANMIA
San Diego
vie. 5/16
6:58 pm-5:43 am
1 stop7h 45m
Miami
vie. 5/23
7:10 am-11:56 am
1 stop7h 46m
$276
San DiegoMiami
SAN - MIA
SANMIA
San Diego
mar. 5/13
8:00 am-7:32 pm
1 stop8h 32m
Miami
lun. 5/19
7:40 am-1:30 pm
1 stop8h 50m
$277
San DiegoMiami
SAN - MIA
SANMIA
San Diego
sáb. 5/10
10:26 am-8:34 pm
1 stop7h 08m
Miami
mar. 5/13
5:00 pm-11:59 pm
2 stops9h 59m
$282
San DiegoMiami
SAN - MIA
SANMIA
San Diego
mar. 5/20
10:25 pm-6:12 am
Nonstop4h 47m
Miami
mié. 5/28
8:15 pm-10:37 pm
Nonstop5h 22m
$292
San DiegoMiami
SAN - MIA
SANMIA
San Diego
dom. 4/20
7:30 am-6:30 pm
1 stop8h 00m
Miami
mar. 4/22
7:35 am-11:50 am
1 stop7h 15m
$326
San DiegoKey West
SAN - EYW
SANEYW
San Diego
dom. 5/18
6:15 am-4:41 pm
2 stops31h 26m
Key West
dom. 5/25
8:53 am-4:19 pm
2 stops34h 26m
$377
San DiegoKey West
SAN - EYW
SANEYW
San Diego
sáb. 5/31
10:20 pm-12:53 pm
1 stop11h 33m
Key West
lun. 6/2
6:45 pm-8:26 pm
2 stops28h 41m
$396
Showing 1-10 of 22 results
Best time to book a flight from San Diego to Florida Keys
Have a flexible travel schedule? Discover the best time to fly to Florida Keys from San Diego with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Diego to Florida Keys
What is the cheapest month to book a flight from San Diego to Florida Keys?
Currently, August is the cheapest month in which you can book a flight from San Diego to Florida Keys (average of $328). Flying from San Diego to Florida Keys in March is currently the most expensive (average of $493). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Rainfall in Florida Keys by month
Plan your trip to Florida Keys by taking into account the average rainfall totals by month.
In terms of precipitation, rainfall in Florida Keys ranges from 1.6 - 9.9 inches per month. September is typically the wettest month, when rainfall can reach 9.9 in. January is typically the driest time to visit Florida Keys when rainfall is around 1.6 in.
Temperature in Florida Keys by month
Plan your trip to Florida Keys by taking into account the average temperature totals by month.
If weather is an important factor for your trip to Florida Keys, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 84.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 68.0 F).
Reviews of airlines servicing Florida Keys
Get insights into the airlines that provide service to Florida Keys. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florida Keys. Reviews last updated abril 17, 2025.
To help decide which airline to fly from San Diego to Florida Keys, see what other customers have to say about Alaska Airlines, Southwest and Delta. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.9
Boarding
8.1
Crew
8.5
Food
7.1
Entertainment
7.1
Overall
8.0
Reviews
1 / 20
10.0
ExcellentCheri,Jan 2025
FAT - SEA
Comfort
7.9
Boarding
8.1
Crew
8.5
Food
7.1
Entertainment
7.1
Overall
8.0
Reviews
1 / 20
10.0
ExcellentCheri,Jan 2025
FAT - SEA
Comfort
7.9
Boarding
8.1
Crew
8.5
Food
7.1
Entertainment
7.1
Overall
8.0
Reviews
1 / 20
10.0
ExcellentCheri,Jan 2025
FAT - SEA
Comfort
7.9
Boarding
8.1
Crew
8.5
Food
7.1
Entertainment
7.1
Overall
8.0
Reviews
1 / 20
10.0
ExcellentCheri,Jan 2025
FAT - SEA
Comfort
7.9
Boarding
8.1
Crew
8.5
Food
7.1
Entertainment
7.1
Overall
8.0
Reviews
1 / 20
10.0
ExcellentCheri,Jan 2025
FAT - SEA
Comfort
7.9
Boarding
8.1
Crew
8.5
Food
7.1
Entertainment
7.1
Overall
8.0
Reviews
1 / 20
10.0
ExcellentCheri,Jan 2025
FAT - SEA
Related info for your journey
Find useful and relevant information for your journey from San Diego to Florida Keys. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes for San Diego to Florida Keys
See prices for flight routes from nearby airports that may be better suited for you.
Top 2 airlines flying from San Diego to Florida Keys
Discover the top 2 airlines that operate flights from San Diego to Florida Keys. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated abril 17, 2025.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$283 | Average$560 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$297 | Average$478 | FlexibilityNo cancel fee | On-timeN/A |