Florida Keys

$124+ Cheap flights from San Diego (SAN) to Florida Keys

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/5. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — EYW
mar. 1 — mar. 81
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Cheap flight deals from San Diego to Florida Keys

Keep the following information in mind while searching for San Diego to Florida Keys flight deals. Data was last updated febrero 24, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$257
(American Airlines)

One-way from

$124
(Kiwi.com)

Popular in

December

Cheapest in

September

Average price

$440
Provider with most accurate pricing for San Diego-Miami flight deals.
Provider most trusted by Cheapflights users for San Diego-Miami flights.
From San Diego to Florida Keys
One-way flight from San Diego to Florida Keys
Highest demand for flights based on searches. 5% potential increase in price ($22 potential increase over avg. RT price).
Cheapest flight prices on average. 1% potential price decrease ($9 potential savings vs. average RT price).
Average for round-trip flights in February 2025

Find flight deals from San Diego to Florida Keys

Cheapest flights from San Diego to Florida Keys
Explore the most affordable flight options available from San Diego to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on febrero 24, 2025.

This American Airlines deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 4/2210:15 pmSAN - MIA
Nonstop4h 47mAmerican Airlines
mié. 4/307:54 pmMIA - SAN
Nonstop5h 44mAmerican Airlines
Deal found 2/24$257
This eDestinos deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 4/76:25 amSAN - MIA
1 stop15h 55mFrontier
jue. 4/1011:36 amMIA - SAN
2 stops39h 38mFrontier
Deal found 2/24$263
This CheapOair deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 3/198:07 pmSAN - MIA
1 stop7h 08mSpirit Airlines
dom. 3/237:20 amMIA - SAN
1 stop27h 21mSpirit Airlines
Deal found 2/24$266
This FlightHub deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 4/78:07 pmSAN - MIA
1 stop7h 08mMultiple Airlines
sáb. 4/128:42 pmMIA - SAN
1 stop17h 47mMultiple Airlines
Deal found 2/24$273
This Delta deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 4/1310:00 pmSAN - MIA
1 stop10h 28mDelta
mar. 4/226:40 pmMIA - SAN
1 stop8h 03mDelta
Deal found 2/24$277
This American Airlines deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 5/19:45 pmSAN - EYW
2 stops10h 08mAmerican Airlines
jue. 5/82:52 pmEYW - SAN
1 stop8h 59mAmerican Airlines
Deal found 2/24$344
This Southwest deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 4/45:30 pmSAN - MIA
2 stops15h 45mSouthwest
mar. 4/87:55 amMIA - SAN
1 stop9h 15mSouthwest
Deal found 2/24$363
This Mytrip deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 5/18:14 amSAN - EYW
2 stops21h 47mMultiple Airlines
jue. 5/84:24 pmEYW - SAN
3 stops42h 04mMultiple Airlines
Deal found 2/24$366
This United Airlines deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 6/186:28 pmSAN - MIA
1 stop8h 17mUnited Airlines
mié. 7/94:17 pmMIA - SAN
1 stop9h 17mUnited Airlines
Deal found 2/23$367
This United Airlines deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 4/2510:00 pmSAN - EYW
1 stop10h 15mUnited Airlines
mar. 4/292:00 pmEYW - SAN
3 stops31h 56mUnited Airlines
Deal found 2/23$443
This Alaska Airlines deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 4/810:45 amSAN - EYW
3 stops21h 56mAlaska Airlines
dom. 4/1312:16 pmEYW - SAN
3 stops24h 15mAlaska Airlines
Deal found 2/23$2,524

Find flights from San Diego to Florida Keys within your budget

Customize your flight search to find flights from San Diego to Florida Keys that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated febrero 24, 2025.

Fly from

San Diego

Fly to

Florida Keys

Route

Depart

Return

Price

San DiegoMiami

SAN - MIA

SANMIA

San Diego

mar. 4/22

10:15 pm-6:02 am

Nonstop4h 47m

Miami

mié. 4/30

7:54 pm-10:38 pm

Nonstop5h 44m

$257

San DiegoMiami

SAN - MIA

SANMIA

San Diego

lun. 4/7

6:25 am-1:20 am

1 stop15h 55m

Miami

jue. 4/10

11:36 am-12:14 am

2 stops39h 38m

$263

San DiegoMiami

SAN - MIA

SANMIA

San Diego

mié. 3/19

8:07 pm-6:15 am

1 stop7h 08m

Miami

dom. 3/23

7:20 am-7:41 am

1 stop27h 21m

$266

San DiegoMiami

SAN - MIA

SANMIA

San Diego

lun. 4/7

8:07 pm-6:15 am

1 stop7h 08m

Miami

sáb. 4/12

8:42 pm-11:29 am

1 stop17h 47m

$273

San DiegoMiami

SAN - MIA

SANMIA

San Diego

dom. 4/13

10:00 pm-11:28 am

1 stop10h 28m

Miami

mar. 4/22

6:40 pm-11:43 pm

1 stop8h 03m

$277

San DiegoKey West

SAN - EYW

SANEYW

San Diego

jue. 5/1

9:45 pm-10:53 am

2 stops10h 08m

Key West

jue. 5/8

2:52 pm-8:51 pm

1 stop8h 59m

$344

San DiegoMiami

SAN - MIA

SANMIA

San Diego

vie. 4/4

5:30 pm-12:15 pm

2 stops15h 45m

Miami

mar. 4/8

7:55 am-2:10 pm

1 stop9h 15m

$363

San DiegoKey West

SAN - EYW

SANEYW

San Diego

jue. 5/1

8:14 am-9:01 am

2 stops21h 47m

Key West

jue. 5/8

4:24 pm-7:28 am

3 stops42h 04m

$366

San DiegoMiami

SAN - MIA

SANMIA

San Diego

mié. 6/18

6:28 pm-5:45 am

1 stop8h 17m

Miami

mié. 7/9

4:17 pm-10:34 pm

1 stop9h 17m

$367

San DiegoKey West

SAN - EYW

SANEYW

San Diego

vie. 4/25

10:00 pm-11:15 am

1 stop10h 15m

Key West

mar. 4/29

2:00 pm-6:56 pm

3 stops31h 56m

$443

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/24

Showing 1-10 of 27 results
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Best time to book a flight from San Diego to Florida Keys

Have a flexible travel schedule? Discover the best time to fly to Florida Keys from San Diego with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from San Diego to Florida Keys

Get recent, data-driven insights about flights from San Diego to Florida Keys including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from San Diego to Florida Keys?

Currently, August is the cheapest month in which you can book a flight from San Diego to Florida Keys (average of $328). Flying from San Diego to Florida Keys in March is currently the most expensive (average of $510). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Rainfall in Florida Keys by month

Plan your trip to Florida Keys by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Florida Keys ranges from 1.6 - 9.9 inches per month. September is typically the wettest month, when rainfall can reach 9.9 in. January is typically the driest time to visit Florida Keys when rainfall is around 1.6 in.

Temperature in Florida Keys by month

Plan your trip to Florida Keys by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Florida Keys, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 84.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 68.0 F).

Reviews of airlines servicing Florida Keys

Get insights into the airlines that provide service to Florida Keys. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florida Keys. Reviews last updated febrero 24, 2025.
To help decide which airline to fly from San Diego to Florida Keys, see what other customers have to say about Southwest, Alaska Airlines and Delta. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Boarding

8.2

Entertainment

7.6

Food

7.1

Comfort

8.1

Crew

8.7

Overall

8.1

Reviews

1 / 20

10.0
Excellent

Merlyn,Feb 2025

LAX - SMF

New Terminal is neat, lost of stores and places to catch a bite.

Boarding

8.2

Entertainment

7.6

Food

7.1

Comfort

8.1

Crew

8.7

Overall

8.1

Reviews

1 / 20

10.0
Excellent

Merlyn,Feb 2025

LAX - SMF

New Terminal is neat, lost of stores and places to catch a bite.

Boarding

8.2

Entertainment

7.6

Food

7.1

Comfort

8.1

Crew

8.7

Overall

8.1

Reviews

1 / 20

10.0
Excellent

Merlyn,Feb 2025

LAX - SMF

New Terminal is neat, lost of stores and places to catch a bite.

8.0
Very good

Boarding

8.2

Entertainment

7.6

Food

7.1

Comfort

8.1

Crew

8.7

Overall

8.1

Reviews

1 / 20

10.0
Excellent

Merlyn,Feb 2025

LAX - SMF

New Terminal is neat, lost of stores and places to catch a bite.

Boarding

8.2

Entertainment

7.6

Food

7.1

Comfort

8.1

Crew

8.7

Overall

8.1

Reviews

1 / 20

10.0
Excellent

Merlyn,Feb 2025

LAX - SMF

New Terminal is neat, lost of stores and places to catch a bite.

Boarding

8.2

Entertainment

7.6

Food

7.1

Comfort

8.1

Crew

8.7

Overall

8.1

Reviews

1 / 20

10.0
Excellent

Merlyn,Feb 2025

LAX - SMF

New Terminal is neat, lost of stores and places to catch a bite.

Related info for your journey

Find useful and relevant information for your journey from San Diego to Florida Keys. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from San Diego to Florida Keys?

    Most people fly from San Diego (SAN) if they book a flight from San Diego to Florida Keys. San Diego is conveniently located just 2.6 mi from San Diego’s city center.

  • What are the cheapest airlines to fly from San Diego to Florida Keys one-way?

    The cheapest airlines for a one-way flight from San Diego to Florida Keys are Spirit Airlines ($124), American Airlines ($125), and JetBlue ($133).

  • Can I find deals for flights from San Diego to Florida Keys that include hotel bookings?

    Yes. In addition to deals on San Diego to Florida Keys flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Diego to Florida Keys?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Diego to Florida Keys.

  • Can I find deals for business class flights from San Diego to Florida Keys?

    Yes. Cheapflights offers flight deals from San Diego to Florida Keys by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Diego to Florida Keys?

    Currently, August is the cheapest month in which you can book a flight from San Diego to Florida Keys (average of $328). Flying from San Diego to Florida Keys in March is currently the most expensive (average of $510). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for San Diego to Florida Keys

See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from San Diego to Florida Keys

Discover the top 2 airlines that operate flights from San Diego to Florida Keys. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated febrero 24, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$298Average$554FlexibilityNo cancel feeOn-time71%
DeltaCheapest$308Average$523FlexibilityNo cancel feeOn-timeN/A
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