HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Florida Keys

$149+ Cheap flights from Panama City, FL (ECP) to Florida Keys

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/25. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — EYW
Feb 4 — Feb 111
Tue 2/4
Tue 2/11
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Panama City to Florida Keys with Cheapflights

1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”
2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.
3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Panama City to Florida Keys

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (ECP) to Florida Keys (zzEOA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 30, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$297
(Southwest)

One-way from

$149
(American Airlines)

Popular in

December

Cheapest in

January

Average price

$332
Provider with most accurate pricing for Panama City NW Florida Beaches-Miami flight deals.
Search Deals
Provider most trusted by Cheapflights users for Panama City NW Florida Beaches-Miami flights.
Search Deals
From Panama City NW Florida Beaches to Florida Keys
Search Deals
One-way flight from Panama City NW Florida Beaches to Florida Keys
Search Deals
High demand for flights, 0% potential price rise
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($15 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2025
Search Deals

Find flight deals from Panama City to Florida Keys

Cheapest flights from Panama City to Florida Keys
Explore the most affordable flight options available from Panama City to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 30, 2025.

This Southwest deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/258:00 amECP - MIA
1 stop4h 50mSouthwest
Wed 2/261:50 pmMIA - ECP
1 stop7h 25mSouthwest
Deal found 1/30$297
This Delta deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/47:45 amECP - MIA
1 stop5h 45mDelta
Tue 6/108:05 amMIA - ECP
1 stop5h 33mDelta
Deal found 1/30$307
This American Airlines deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/282:36 pmECP - MIA
1 stop6h 01mAmerican Airlines
Fri 3/287:04 amMIA - ECP
1 stop6h 28mAmerican Airlines
Deal found 1/30$317
This United Airlines deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/186:30 amECP - MIA
2 stops15h 15mUnited Airlines
Mon 3/247:00 amMIA - ECP
3 stops30h 34mUnited Airlines
Deal found 1/29$606
This American Airlines deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/204:28 pmECP - EYW
2 stops19h 46mAmerican Airlines
Mon 2/247:29 pmEYW - ECP
2 stops19h 23mAmerican Airlines
Deal found 1/30$656
This United deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/201:13 pmECP - EYW
1 stop25h 56mUnited Airlines
Mon 2/243:05 pmEYW - ECP
2 stops29h 52mUnited Airlines
Deal found 1/30$731
This Delta deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/206:00 amECP - EYW
1 stop4h 38mDelta
Mon 2/246:14 pmEYW - ECP
1 stop5h 49mDelta
Deal found 1/30$739

Find flights from Panama City to Florida Keys within your budget

Customize your flight search to find flights from Panama City to Florida Keys that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 30, 2025.

Fly from

Any airport

Fly to

Any airport

Route

Depart

Return

Price

Panama CityMiami

ECP - MIA

ECPMIA

Panama City NW Florida Beaches

Tue 2/25

8:00 am-1:50 pm

1 stop4h 50m

Miami

Wed 2/26

1:50 pm-8:15 pm

1 stop7h 25m

$297

Panama CityMiami

ECP - MIA

ECPMIA

Panama City NW Florida Beaches

Wed 6/4

7:05 pm-12:54 am

1 stop4h 49m

Miami

Wed 6/11

5:55 pm-10:41 pm

1 stop5h 46m

$307

Panama CityMiami

ECP - MIA

ECPMIA

Panama City NW Florida Beaches

Fri 2/28

2:36 pm-9:37 pm

1 stop6h 01m

Miami

Fri 3/28

7:04 am-12:32 pm

1 stop6h 28m

$317

Panama CityMiami

ECP - MIA

ECPMIA

Panama City NW Florida Beaches

Tue 3/18

6:30 am-10:45 pm

2 stops15h 15m

Miami

Mon 3/24

7:00 am-12:34 pm

3 stops30h 34m

$606

Panama CityKey West

ECP - EYW

ECPEYW

Panama City NW Florida Beaches

Thu 2/20

4:28 pm-1:14 pm

2 stops19h 46m

Key West

Mon 2/24

7:29 pm-1:52 pm

2 stops19h 23m

$656

Panama CityKey West

ECP - EYW

ECPEYW

Panama City NW Florida Beaches

Thu 2/20

1:13 pm-4:09 pm

1 stop25h 56m

Key West

Mon 2/24

3:05 pm-7:57 pm

2 stops29h 52m

$731

Panama CityKey West

ECP - EYW

ECPEYW

Panama City NW Florida Beaches

Thu 2/20

6:00 am-11:38 am

1 stop4h 38m

Key West

Mon 2/24

6:14 pm-11:03 pm

1 stop5h 49m

$739

Panama CityMiami

ECP - MIA

ECPMIA

Panama City NW Florida Beaches

Tue 2/25

2:36 pm-9:37 pm

1 stop6h 01m

$149

Panama CityMiami

ECP - MIA

ECPMIA

Panama City NW Florida Beaches

Tue 2/25

8:00 am-10:10 pm

2 stops13h 10m

$159

Panama CityMiami

ECP - MIA

ECPMIA

Panama City NW Florida Beaches

Fri 5/2

7:05 pm-12:54 am

1 stop4h 49m

$164

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/30

Showing 1-10 of 11 results
1
2

Best time to book a flight from Panama City to Florida Keys

Have a flexible travel schedule? Discover the best time to fly to Florida Keys from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Panama City to Florida Keys

Get recent, data-driven insights about flights from Panama City to Florida Keys including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Panama City, Florida to Florida Keys?

Currently, August is the cheapest month in which you can book a flight from Panama City, Florida to Florida Keys (average of $328). Flying from Panama City, Florida to Florida Keys in March is currently the most expensive (average of $526). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Rainfall in Florida Keys by month

Plan your trip to Florida Keys by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Florida Keys ranges from 1.6 - 9.9 inches per month. September is typically the wettest month, when rainfall can reach 9.9 in. January is typically the driest time to visit Florida Keys when rainfall is around 1.6 in.

Temperature in Florida Keys by month

Plan your trip to Florida Keys by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Florida Keys, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 84.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 68.0 F).

Reviews of airlines servicing Florida Keys

Get insights into the airlines that provide service to Florida Keys. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florida Keys. Reviews last updated January 30, 2025.
To help decide which airline to fly from Panama City to Florida Keys, see what other customers have to say about Southwest, Delta and United Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
4,585 reviews

Crew

8.7

Food

7.1

Entertainment

7.7

Boarding

8.2

Comfort

8.1

Overall

8.1

Reviews

1 / 20

10.0
Excellent

Bob,Jan 2024

TPA - RDU

No tray tables for food or drink not convenient nor comfortable

Southwest
8.1
Very good
4,585 reviews
Southwest
8.1
Very good
4,585 reviews

Crew

8.7

Food

7.1

Entertainment

7.7

Boarding

8.2

Comfort

8.1

Overall

8.1

Reviews

1 / 20

10.0
Excellent

Bob,Jan 2024

TPA - RDU

No tray tables for food or drink not convenient nor comfortable

Delta
8.0
Very good
8,454 reviews
Southwest
8.1
Very good
4,585 reviews

Crew

8.7

Food

7.1

Entertainment

7.7

Boarding

8.2

Comfort

8.1

Overall

8.1

Reviews

1 / 20

10.0
Excellent

Bob,Jan 2024

TPA - RDU

No tray tables for food or drink not convenient nor comfortable

United Airlines
7.4
Good
8,913 reviews
Southwest
8.1
Very good
4,585 reviews

Crew

8.7

Food

7.1

Entertainment

7.7

Boarding

8.2

Comfort

8.1

Overall

8.1

Reviews

1 / 20

10.0
Excellent

Bob,Jan 2024

TPA - RDU

No tray tables for food or drink not convenient nor comfortable

American Airlines
7.2
Good
10,000 reviews
Southwest
8.1
Very good
4,585 reviews

Crew

8.7

Food

7.1

Entertainment

7.7

Boarding

8.2

Comfort

8.1

Overall

8.1

Reviews

1 / 20

10.0
Excellent

Bob,Jan 2024

TPA - RDU

No tray tables for food or drink not convenient nor comfortable

Related info for your journey

Find useful and relevant information for your journey from Panama City to Florida Keys. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Panama City to Florida Keys?

    If you book a flight to Florida Keys from Panama City, you will be flying from NW Florida Beaches, which is the city’s only airport. Panama City NW Florida Beaches (ECP) is located 16.0 mi from the center of Panama City.

  • What are the cheapest airlines to fly from Panama City, Florida to Florida Keys one-way?

    To fly one-way, consider booking your trip with American Airlines, which is currently one of the cheapest options available, starting at $149. Southwest flights start at $159 while deals on Delta start at $164 one-way.

  • Can I find deals for flights from Panama City to Florida Keys that include hotel bookings?

    Yes. In addition to deals on Panama City to Florida Keys flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Florida Keys?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Florida Keys.

  • Can I find deals for business class flights from Panama City to Florida Keys?

    Yes. Cheapflights offers flight deals from Panama City to Florida Keys by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City, Florida to Florida Keys?

    Currently, August is the cheapest month in which you can book a flight from Panama City, Florida to Florida Keys (average of $328). Flying from Panama City, Florida to Florida Keys in March is currently the most expensive (average of $526). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Panama City to Florida Keys

See prices for flight routes from nearby airports that may be better suited for you.
Tampa to Miami flights
Tampa to Fort Lauderdale flights
Orlando to Miami flights
Miami to Orlando flights
Miami to Tampa flights
Fort Lauderdale to Tampa flights
Pensacola to Orlando flights
Jacksonville to Miami flights
Fort Lauderdale to Orlando flights
Tampa to Key West flights
Orlando to Fort Lauderdale flights
Tallahassee to Fort Lauderdale flights
Orlando to Key West flights
Pensacola to Miami flights
Miami to Jacksonville flights
Jacksonville to Fort Lauderdale flights
Pensacola to Fort Lauderdale flights
Tampa to Pensacola flights
Fort Lauderdale to Jacksonville flights
Fort Lauderdale to Tallahassee flights
Orlando to Pensacola flights
Tallahassee to Miami flights
Miami to Tallahassee flights
Fort Lauderdale to Pensacola flights
Pensacola to Tampa flights
Fort Lauderdale to Key West flights
Miami to Pensacola flights
Miami to Key West flights
Sarasota to Key West flights
Tampa to West Palm Beach flights
Jacksonville to Key West flights
West Palm Beach to Tampa flights
Fort Myers to Key West flights
West Palm Beach to Tallahassee flights
Tallahassee to West Palm Beach flights
Fort Myers to Orlando flights
Miami to Panama City flights
Tampa to Jacksonville flights
Tampa to Orlando flights
Jacksonville to West Palm Beach flights
Fort Lauderdale to Panama City flights
Sarasota to Miami flights
Tampa to Tallahassee flights
Miami to Fort Lauderdale flights
Valparaiso to Fort Lauderdale flights
Fort Myers to Miami flights
Valparaiso to Miami flights
Fort Myers to Pensacola flights
Fort Lauderdale to Gainesville flights
Jacksonville to Fort Myers flights

Top 2 airlines flying from Panama City to Florida Keys

Discover the top 2 airlines that operate flights from Panama City to Florida Keys. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$298Average$474FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$393Average$581FlexibilityNo cancel feeOn-time71%
100% Free
Cheapflights is completely free to use, so you can start saving the moment you arrive.
Book with Flexibility
Our users can plan ahead with confidence and find flights with no change fees
Travel Smart
Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.