$69+ Cheap flights from Myrtle Beach (MYR) to Florida Keys
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/29. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — EYW
Apr 5 — Apr 121
1 adult, Economy
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Find cheap flights from Myrtle Beach to Florida Keys with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Myrtle Beach to Florida Keys
Keep the following information in mind while searching for Myrtle Beach to Florida Keys flight deals. Data was last updated March 31, 2025.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $146 (Cheapflightsfares) |
One-way from | $69 (FlightHub) |
Popular in | February |
Cheapest in | June |
Average price | $350 |
Find flight deals from Myrtle Beach to Florida Keys
Cheapest flights from Myrtle Beach to Florida KeysExplore the most affordable flight options available from Myrtle Beach to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 31, 2025.
Explore the most affordable flight options available from Myrtle Beach to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 31, 2025.
This Cheapflightsfares deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2912:20 pmMYR - MIA
1 stop6h 50mSpirit Airlines
Tue 5/610:57 amMIA - MYR
1 stop6h 08mSpirit Airlines
Deal found 3/30![Spirit Airlines logo]()
$146
This Frontier deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/1011:52 amMYR - MIA
1 stop11h 34mFrontier
Sun 5/186:00 amMIA - MYR
1 stop8h 09mFrontier
Deal found 3/30![Frontier logo]()
$158
This American Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/255:00 amMYR - EYW
1 stop7h 10mAmerican Airlines
Tue 6/35:24 pmEYW - MYR
1 stop5h 07mAmerican Airlines
Deal found 3/31![American Airlines logo]()
$200
This Expedia deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/2010:37 amMYR - MIA
1 stop12h 38mMultiple Airlines
Thu 5/15:45 amMIA - MYR
1 stop10h 13mMultiple Airlines
Deal found 3/30![Multiple Airlines logo]()
$215
This Delta deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/226:45 pmMYR - MIA
1 stop6h 15mDelta
Tue 8/266:00 amMIA - MYR
1 stop4h 11mDelta
Deal found 3/31![Delta logo]()
$302
This Southwest deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1911:20 amMYR - MIA
1 stop11h 00mSouthwest
Sat 4/265:50 amMIA - MYR
1 stop7h 45mSouthwest
Deal found 3/30![Southwest logo]()
$307
This American Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/227:19 amMYR - MIA
1 stop6h 05mAmerican Airlines
Sat 8/307:05 amMIA - MYR
1 stop5h 10mAmerican Airlines
Deal found 3/31![American Airlines logo]()
$317
This Mytrip deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/2612:08 pmMYR - EYW
2 stops27h 26mMultiple Airlines
Sat 5/33:46 pmEYW - MYR
2 stops22h 59mMultiple Airlines
Deal found 3/29![Multiple Airlines logo]()
$334
This United deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/65:16 pmMYR - MIA
2 stops18h 04mUnited Airlines
Sun 9/148:00 amMIA - MYR
1 stop8h 19mUnited Airlines
Deal found 3/31![United Airlines logo]()
$482
This Delta deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/286:00 amMYR - EYW
1 stop4h 53mDelta
Sat 7/57:50 amEYW - MYR
1 stop4h 31mDelta
Deal found 3/30![Delta logo]()
$523
This United Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/110:58 amMYR - EYW
2 stops31h 07mUnited Airlines
Mon 7/72:45 pmEYW - MYR
2 stops25h 45mUnited Airlines
Deal found 3/30![United Airlines logo]()
$525
This KAYAK deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/154:23 pmMYR - EYW
3 stops40h 59mBreeze Airways
Mon 8/181:47 pmEYW - MYR
2 stops19h 21mBreeze Airways
Deal found 3/30![Breeze Airways logo]()
$1,091
Cheapflights Fare Finder
Customize your flight search to find flights from Myrtle Beach to Florida Keys that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 31, 2025.
Use the filters below to find and compare flights from Myrtle Beach to Florida Keys that are best for you.
Fly from
Myrtle Beach
Fly to
Florida Keys
Route
Depart
Return
Price
Myrtle BeachMiami
MYR - MIA
MYRMIA
Myrtle Beach Intl
Tue 4/29
12:20 pm-7:10 pm
1 stop6h 50m
Miami
Tue 5/6
10:57 am-5:05 pm
1 stop6h 08m
$146
Myrtle BeachMiami
MYR - MIA
MYRMIA
Myrtle Beach Intl
Sat 5/10
11:52 am-11:26 pm
1 stop11h 34m
Miami
Sun 5/18
6:00 am-2:09 pm
1 stop8h 09m
$158
Myrtle BeachKey West
MYR - EYW
MYREYW
Myrtle Beach Intl
Sun 5/25
5:00 am-12:10 pm
1 stop7h 10m
Key West
Tue 6/3
5:24 pm-10:31 pm
1 stop5h 07m
$200
Myrtle BeachMiami
MYR - MIA
MYRMIA
Myrtle Beach Intl
Sun 4/20
10:37 am-11:15 pm
1 stop12h 38m
Miami
Thu 5/1
5:45 am-3:58 pm
1 stop10h 13m
$215
Myrtle BeachMiami
MYR - MIA
MYRMIA
Myrtle Beach Intl
Thu 5/15
3:00 pm-8:45 pm
1 stop5h 45m
Miami
Thu 5/22
11:45 am-5:39 pm
1 stop5h 54m
$288
Myrtle BeachMiami
MYR - MIA
MYRMIA
Myrtle Beach Intl
Fri 8/22
6:45 pm-1:00 am
1 stop6h 15m
Miami
Tue 8/26
6:00 am-10:11 am
1 stop4h 11m
$302
Myrtle BeachMiami
MYR - MIA
MYRMIA
Myrtle Beach Intl
Sat 4/19
11:20 am-10:20 pm
1 stop11h 00m
Miami
Sat 4/26
5:50 am-1:35 pm
1 stop7h 45m
$307
Myrtle BeachKey West
MYR - EYW
MYREYW
Myrtle Beach Intl
Sat 4/26
12:08 pm-3:34 pm
2 stops27h 26m
Key West
Sat 5/3
3:46 pm-2:45 pm
2 stops22h 59m
$334
Myrtle BeachMiami
MYR - MIA
MYRMIA
Myrtle Beach Intl
Sat 9/6
5:16 pm-11:20 am
2 stops18h 04m
Miami
Sun 9/14
8:00 am-4:19 pm
1 stop8h 19m
$482
Myrtle BeachKey West
MYR - EYW
MYREYW
Myrtle Beach Intl
Sat 6/28
6:00 am-10:53 am
1 stop4h 53m
Key West
Sat 7/5
7:50 am-12:21 pm
1 stop4h 31m
$523
Showing 1-10 of 18 results
Best time to book a flight from Myrtle Beach to Florida Keys
Have a flexible travel schedule? Discover the best time to fly to Florida Keys from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Myrtle Beach to Florida Keys
What is the cheapest month to book a flight from Myrtle Beach to Florida Keys?
Currently, August is the cheapest month in which you can book a flight from Myrtle Beach to Florida Keys (average of $328). Flying from Myrtle Beach to Florida Keys in March is currently the most expensive (average of $493). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MYR to EOA?
Find hourly flight availability from Myrtle Beach to Florida Keys. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 31, 2025.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Myrtle Beach to Florida Keys as you normally would.
Rainfall in Florida Keys by month
Plan your trip to Florida Keys by taking into account the average rainfall totals by month.
In terms of precipitation, rainfall in Florida Keys ranges from 1.6 - 9.9 inches per month. September is typically the wettest month, when rainfall can reach 9.9 in. January is typically the driest time to visit Florida Keys when rainfall is around 1.6 in.
Temperature in Florida Keys by month
Plan your trip to Florida Keys by taking into account the average temperature totals by month.
If weather is an important factor for your trip to Florida Keys, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 84.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 68.0 F).
Reviews of airlines servicing Florida Keys
Get insights into the airlines that provide service to Florida Keys. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florida Keys. Reviews last updated March 31, 2025.
To help decide which airline to fly from Myrtle Beach to Florida Keys, see what other customers have to say about Breeze Airways, Southwest and Delta. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
6.6
Overall
8.1
Comfort
8.2
Boarding
8.3
Crew
8.8
Food
6.7
Reviews
1 / 11
10.0
ExcellentDena,Dec 2024
LAS - BDL
Entertainment
6.6
Overall
8.1
Comfort
8.2
Boarding
8.3
Crew
8.8
Food
6.7
Reviews
1 / 11
10.0
ExcellentDena,Dec 2024
LAS - BDL
Entertainment
6.6
Overall
8.1
Comfort
8.2
Boarding
8.3
Crew
8.8
Food
6.7
Reviews
1 / 11
10.0
ExcellentDena,Dec 2024
LAS - BDL
Entertainment
6.6
Overall
8.1
Comfort
8.2
Boarding
8.3
Crew
8.8
Food
6.7
Reviews
1 / 11
10.0
ExcellentDena,Dec 2024
LAS - BDL
Entertainment
6.6
Overall
8.1
Comfort
8.2
Boarding
8.3
Crew
8.8
Food
6.7
Reviews
1 / 11
10.0
ExcellentDena,Dec 2024
LAS - BDL
Entertainment
6.6
Overall
8.1
Comfort
8.2
Boarding
8.3
Crew
8.8
Food
6.7
Reviews
1 / 11
10.0
ExcellentDena,Dec 2024
LAS - BDL
Related info for your journey
Find useful and relevant information for your journey from Myrtle Beach to Florida Keys. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Myrtle Beach to Florida Keys
See prices for flight routes from nearby airports that may be better suited for you.
Top 2 airlines flying from Myrtle Beach to Florida Keys
Discover the top 2 airlines that operate flights from Myrtle Beach to Florida Keys. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 31, 2025.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$208 | Average$440 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$261 | Average$479 | FlexibilityNo cancel fee | On-time71% |