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$76+ Cheap flights from Myrtle Beach (MYR) to Florida Keys

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/29. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — EYW
Feb 28 — Mar 71
Fri 2/28
Fri 3/7
1 adult, Economy
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Cheap flight deals from Myrtle Beach to Florida Keys

Keep the following information in mind while searching for Myrtle Beach to Florida Keys flight deals. Data was last updated February 23, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$150
(Mytrip)

One-way from

$76
(Cheapflightsfares)

Popular in

February

Cheapest in

April

Average price

$396
Provider with most accurate pricing for Myrtle Beach Intl-Miami flight deals.
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Provider most trusted by Cheapflights users for Myrtle Beach Intl-Miami flights.
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From Myrtle Beach Intl to Florida Keys
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One-way flight from Myrtle Beach Intl to Florida Keys
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Highest demand for flights based on searches. 17% potential increase in price ($61 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($11 potential savings vs. average RT price).
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Average for round-trip flights in February 2025
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Find flight deals from Myrtle Beach to Florida Keys

Cheapest flights from Myrtle Beach to Florida Keys
Explore the most affordable flight options available from Myrtle Beach to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 23, 2025.

This Mytrip deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/267:06 amMYR - MIA
1 stop9h 59mSpirit Airlines
Tue 4/18:59 amMIA - MYR
2 stops29h 46mSpirit Airlines
Deal found 2/22$150
This FlightHub deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/210:47 pmMYR - MIA
1 stop10h 58mMultiple Airlines
Sun 5/116:00 amMIA - MYR
1 stop8h 09mMultiple Airlines
Deal found 2/22$154
This Delta deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/221:05 pmMYR - MIA
1 stop5h 50mDelta
Tue 8/2610:20 amMIA - MYR
1 stop4h 41mDelta
Deal found 2/22$347
This Mytrip deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/2410:27 pmMYR - EYW
2 stops18h 02mMultiple Airlines
Wed 3/263:06 pmEYW - MYR
2 stops27h 40mMultiple Airlines
Deal found 2/22$353
This American Airlines deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/254:19 pmMYR - MIA
1 stop3h 49mAmerican Airlines
Fri 8/298:19 amMIA - MYR
1 stop5h 40mAmerican Airlines
Deal found 2/21$372
This American Airlines deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/245:10 amMYR - EYW
1 stop7h 13mAmerican Airlines
Wed 3/261:45 pmEYW - MYR
2 stops8h 35mAmerican Airlines
Deal found 2/22$373
This Southwest deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/314:25 pmMYR - MIA
1 stop5h 50mSouthwest
Sat 6/71:35 pmMIA - MYR
2 stops7h 55mSouthwest
Deal found 2/22$402
This United deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/66:09 pmMYR - MIA
2 stops17h 12mUnited Airlines
Sun 9/147:25 amMIA - MYR
1 stop6h 50mUnited Airlines
Deal found 2/22$485
This Delta deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/1011:32 amMYR - EYW
1 stop5h 48mDelta
Thu 3/136:15 pmEYW - MYR
1 stop5h 34mDelta
Deal found 2/22$589
This United Airlines deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/3110:03 amMYR - EYW
2 stops23h 12mUnited Airlines
Sat 6/710:55 amEYW - MYR
2 stops27h 40mUnited Airlines
Deal found 2/22$666

Find flights from Myrtle Beach to Florida Keys within your budget

Customize your flight search to find flights from Myrtle Beach to Florida Keys that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 23, 2025.

Fly from

Myrtle Beach

Fly to

Florida Keys

Route

Depart

Return

Price

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Wed 3/26

7:06 am-5:05 pm

1 stop9h 59m

Miami

Tue 4/1

8:59 am-2:45 pm

2 stops29h 46m

$150

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Fri 5/2

10:47 pm-9:45 am

1 stop10h 58m

Miami

Sun 5/11

6:00 am-2:09 pm

1 stop8h 09m

$154

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Mon 3/24

10:27 pm-4:29 pm

2 stops18h 02m

Key West

Wed 3/26

3:06 pm-6:46 pm

2 stops27h 40m

$353

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Mon 3/24

5:10 am-12:23 pm

1 stop7h 13m

Key West

Wed 3/26

1:45 pm-10:20 pm

2 stops8h 35m

$373

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Tue 4/8

3:30 pm-9:55 pm

1 stop6h 25m

Miami

Sun 4/13

2:45 pm-11:00 pm

2 stops8h 15m

$412

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Tue 4/22

4:53 pm-11:51 pm

1 stop6h 58m

Miami

Sat 4/26

7:00 am-2:43 pm

1 stop7h 43m

$543

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Mon 3/10

11:32 am-5:20 pm

1 stop5h 48m

Key West

Thu 3/13

6:15 pm-11:49 pm

1 stop5h 34m

$589

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Tue 4/29

10:47 pm-9:45 am

1 stop10h 58m

$76

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Mon 4/7

7:00 pm-10:29 am

1 stop15h 29m

$218

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/22

Best time to book a flight from Myrtle Beach to Florida Keys

Have a flexible travel schedule? Discover the best time to fly to Florida Keys from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Myrtle Beach to Florida Keys

Get recent, data-driven insights about flights from Myrtle Beach to Florida Keys including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Myrtle Beach to Florida Keys?

Currently, August is the cheapest month in which you can book a flight from Myrtle Beach to Florida Keys (average of $328). Flying from Myrtle Beach to Florida Keys in March is currently the most expensive (average of $510). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MYR to EOA?

Find hourly flight availability from Myrtle Beach to Florida Keys. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 23, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Myrtle Beach to Florida Keys as you normally would.

Rainfall in Florida Keys by month

Plan your trip to Florida Keys by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Florida Keys ranges from 1.6 - 9.9 inches per month. September is typically the wettest month, when rainfall can reach 9.9 in. January is typically the driest time to visit Florida Keys when rainfall is around 1.6 in.

Temperature in Florida Keys by month

Plan your trip to Florida Keys by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Florida Keys, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 84.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 68.0 F).

Reviews of airlines servicing Florida Keys

Get insights into the airlines that provide service to Florida Keys. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florida Keys. Reviews last updated February 23, 2025.
To help decide which airline to fly from Myrtle Beach to Florida Keys, see what other customers have to say about Southwest, Delta and United Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
4,396 reviews

Boarding

8.2

Crew

8.7

Comfort

8.1

Entertainment

7.6

Food

7.1

Overall

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Southwest
8.1
Very good
4,396 reviews
Southwest
8.1
Very good
4,396 reviews

Boarding

8.2

Crew

8.7

Comfort

8.1

Entertainment

7.6

Food

7.1

Overall

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Delta
8.0
Very good
8,203 reviews
Southwest
8.1
Very good
4,396 reviews

Boarding

8.2

Crew

8.7

Comfort

8.1

Entertainment

7.6

Food

7.1

Overall

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

United Airlines
7.4
Good
8,754 reviews
Southwest
8.1
Very good
4,396 reviews

Boarding

8.2

Crew

8.7

Comfort

8.1

Entertainment

7.6

Food

7.1

Overall

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

American Airlines
7.2
Good
10,000 reviews
Southwest
8.1
Very good
4,396 reviews

Boarding

8.2

Crew

8.7

Comfort

8.1

Entertainment

7.6

Food

7.1

Overall

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Spirit Airlines
6.3
Okay
8,012 reviews
Southwest
8.1
Very good
4,396 reviews

Boarding

8.2

Crew

8.7

Comfort

8.1

Entertainment

7.6

Food

7.1

Overall

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to Florida Keys. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Myrtle Beach to Florida Keys?

    Myrtle Beach Intl (MYR) is the airport you will fly out of if you book a flight from Myrtle Beach to Florida Keys. It is only a 2.1 mi journey to Myrtle Beach Intl (MYR) from Myrtle Beach’s city center.

  • Can I find deals for flights from Myrtle Beach to Florida Keys that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to Florida Keys flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to Florida Keys?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to Florida Keys.

  • Can I find deals for business class flights from Myrtle Beach to Florida Keys?

    Yes. Cheapflights offers flight deals from Myrtle Beach to Florida Keys by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Myrtle Beach to Florida Keys?

    Currently, August is the cheapest month in which you can book a flight from Myrtle Beach to Florida Keys (average of $328). Flying from Myrtle Beach to Florida Keys in March is currently the most expensive (average of $510). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Top 2 airlines flying from Myrtle Beach to Florida Keys

Discover the top 2 airlines that operate flights from Myrtle Beach to Florida Keys. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 23, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$208Average$440FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$256Average$488FlexibilityNo cancel feeOn-time71%
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