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Florida Keys

$55+ Cheap flights from Missouri to Florida Keys

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/7. Fares are subject to change and may not be available on all flights or dates of travel.
STL — EYW
Feb 25 — Mar 41
Tue 2/25
Tue 3/4
1 adult, Economy
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Cheap flight deals from Missouri to Florida Keys

Keep the following information in mind while searching for Missouri to Florida Keys flight deals. Data was last updated February 20, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$250
(CheapOair)

One-way from

$55
(Cheapflightsfares)

Popular in

April

Cheapest in

November

Average price

$520
Provider with most accurate pricing for Kansas City Downtown-Miami flight deals.
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From Missouri to Florida Keys
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One-way flight from Missouri to Florida Keys
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Highest demand for flights based on searches. 23% potential increase in price ($143 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($19 potential savings vs. average RT price).
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Average for round-trip flights in February 2025
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Find flight deals from Missouri to Florida Keys

Cheapest flights from Missouri to Florida Keys
Explore the most affordable flight options available from Missouri to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 20, 2025.

This CheapOair deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1111:40 amMCI - MIA
1 stop17h 30mMultiple Airlines
Sun 3/166:25 amMIA - MCI
1 stop14h 10mMultiple Airlines
Deal found 2/18$250
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/125:09 amMCI - MIA
Nonstop3h 06mAmerican Airlines
Wed 4/168:40 pmMIA - MCI
Nonstop3h 22mAmerican Airlines
Deal found 2/19$253
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/95:30 pmMCI - MIA
1 stop6h 22mDelta
Thu 4/172:55 pmMIA - MCI
1 stop6h 09mDelta
Deal found 2/19$257
This Mytrip deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1110:20 amMCI - MIA
3 stops28h 57mSpirit Airlines
Sun 3/1610:25 pmMIA - MCI
3 stops18h 19mSpirit Airlines
Deal found 2/18$258
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/196:49 pmSGF - MIA
1 stop4h 56mDelta
Wed 3/261:38 pmMIA - SGF
1 stop5h 31mDelta
Deal found 2/19$259
This Gotogate deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/118:35 pmMCI - MIA
1 stop7h 46mFrontier
Mon 4/146:25 amMIA - MCI
1 stop14h 12mFrontier
Deal found 2/19$259
This Mytrip deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/137:37 pmSTL - MIA
3 stops27h 49mMultiple Airlines
Tue 5/2011:34 amMIA - STL
3 stops25h 11mMultiple Airlines
Deal found 2/20$261
This Mytrip deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/115:38 pmSTL - MIA
2 stops26h 02mSpirit Airlines
Fri 3/142:23 pmMIA - STL
2 stops19h 46mSpirit Airlines
Deal found 2/19$262
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/251:48 pmSTL - MIA
1 stop7h 35mAmerican Airlines
Tue 4/298:15 pmMIA - STL
Nonstop3h 04mAmerican Airlines
Deal found 2/20$263
This Southwest deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1312:30 pmSTL - MIA
1 stop7h 35mSouthwest
Tue 5/2012:45 pmMIA - STL
2 stops8h 15mSouthwest
Deal found 2/20$264
This Mytrip deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/87:04 pmSTL - MIA
1 stop7h 51mFrontier
Tue 3/116:25 amMIA - STL
1 stop27h 51mFrontier
Deal found 2/20$268
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/198:49 amSTL - EYW
1 stop6h 55mAmerican Airlines
Wed 3/265:24 pmEYW - STL
1 stop7h 32mAmerican Airlines
Deal found 2/19$269

Find flights from Missouri to Florida Keys within your budget

Customize your flight search to find flights from Missouri to Florida Keys that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.

Fly from

Missouri

Fly to

Florida Keys

Route

Depart

Return

Price

Kansas CityKey West

MCI - EYW

MCIEYW

Kansas City

Wed 3/12

5:30 am-2:27 pm

2 stops7h 57m

Key West

Tue 3/18

7:55 am-3:08 pm

1 stop8h 13m

$249

Kansas CityMiami

MCI - MIA

MCIMIA

Kansas City

Tue 3/11

11:40 am-6:10 am

1 stop17h 30m

Miami

Sun 3/16

6:25 am-7:35 pm

1 stop14h 10m

$250

Kansas CityMiami

MCI - MIA

MCIMIA

Kansas City

Sat 4/12

5:09 am-9:15 am

Nonstop3h 06m

Miami

Wed 4/16

8:40 pm-11:02 pm

Nonstop3h 22m

$253

Kansas CityMiami

MCI - MIA

MCIMIA

Kansas City

Wed 4/9

5:30 pm-12:52 am

1 stop6h 22m

Miami

Thu 4/17

2:55 pm-8:04 pm

1 stop6h 09m

$257

Kansas CityMiami

MCI - MIA

MCIMIA

Kansas City

Tue 3/11

10:20 am-4:17 pm

3 stops28h 57m

Miami

Sun 3/16

10:25 pm-3:44 pm

3 stops18h 19m

$258

St. LouisMiami

STL - MIA

STLMIA

Lambert-St Louis

Tue 3/25

4:42 pm-8:29 pm

Nonstop2h 47m

Miami

Tue 4/1

7:28 pm-11:56 pm

1 stop5h 28m

$258

Kansas CityMiami

MCI - MIA

MCIMIA

Kansas City

Fri 4/11

8:35 pm-5:21 am

1 stop7h 46m

Miami

Mon 4/14

6:25 am-7:37 pm

1 stop14h 12m

$259

SpringfieldMiami

SGF - MIA

SGFMIA

Springfield-Branson

Wed 3/19

6:49 pm-12:45 am

1 stop4h 56m

Miami

Wed 3/26

1:38 pm-6:09 pm

1 stop5h 31m

$259

St. LouisMiami

STL - MIA

STLMIA

Lambert-St Louis

Fri 5/9

6:53 pm-5:22 am

1 stop9h 29m

Miami

Sun 5/18

6:00 am-9:09 am

1 stop28h 09m

$260

St. LouisMiami

STL - MIA

STLMIA

Lambert-St Louis

Fri 4/25

12:15 pm-10:56 am

2 stops21h 41m

Miami

Tue 4/29

5:45 am-5:16 pm

2 stops12h 31m

$261

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/19

Showing 1-10 of 56 results
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Best time to book a flight from Missouri to Florida Keys

Have a flexible travel schedule? Discover the best time to fly to Florida Keys from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Missouri to Florida Keys

Get recent, data-driven insights about flights from Missouri to Florida Keys including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Missouri to Florida Keys?

Currently, August is the cheapest month in which you can book a flight from Missouri to Florida Keys (average of $328). Flying from Missouri to Florida Keys in March is currently the most expensive (average of $510). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to EOA?

Find hourly flight availability from Missouri to Florida Keys. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 20, 2025.

When flying from Missouri to Florida Keys, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Florida Keys by month

Plan your trip to Florida Keys by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Florida Keys ranges from 1.6 - 9.9 inches per month. September is typically the wettest month, when rainfall can reach 9.9 in. January is typically the driest time to visit Florida Keys when rainfall is around 1.6 in.

Temperature in Florida Keys by month

Plan your trip to Florida Keys by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Florida Keys, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 84.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 68.0 F).

Reviews of airlines servicing Florida Keys

Get insights into the airlines that provide service to Florida Keys. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florida Keys. Reviews last updated February 20, 2025.
See what other customers who have flown with Southwest, Alaska Airlines and Delta from Missouri to Florida Keys have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
4,411 reviews

Entertainment

7.6

Overall

8.1

Food

7.1

Crew

8.7

Boarding

8.2

Comfort

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Southwest
8.1
Very good
4,411 reviews
Southwest
8.1
Very good
4,411 reviews

Entertainment

7.6

Overall

8.1

Food

7.1

Crew

8.7

Boarding

8.2

Comfort

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Alaska Airlines
8.0
Very good
9,692 reviews
Southwest
8.1
Very good
4,411 reviews

Entertainment

7.6

Overall

8.1

Food

7.1

Crew

8.7

Boarding

8.2

Comfort

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Delta
8.0
Very good
8,220 reviews
Southwest
8.1
Very good
4,411 reviews

Entertainment

7.6

Overall

8.1

Food

7.1

Crew

8.7

Boarding

8.2

Comfort

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

United Airlines
7.4
Good
8,766 reviews
Southwest
8.1
Very good
4,411 reviews

Entertainment

7.6

Overall

8.1

Food

7.1

Crew

8.7

Boarding

8.2

Comfort

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Allegiant Air
7.3
Good
765 reviews
Southwest
8.1
Very good
4,411 reviews

Entertainment

7.6

Overall

8.1

Food

7.1

Crew

8.7

Boarding

8.2

Comfort

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Florida Keys. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Missouri to Florida Keys one-way?

    One-way options have recently been found by users for as low as $55 on Frontier. Other airlines that offer cheap prices include American Airlines from $90 and Delta from $100 one-way.

  • Can I find deals for flights from Missouri to Florida Keys that include hotel bookings?

    Yes. In addition to deals on Missouri to Florida Keys flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Florida Keys?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Florida Keys.

  • Can I find deals for business class flights from Missouri to Florida Keys?

    Yes. Cheapflights offers flight deals from Missouri to Florida Keys by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Florida Keys?

    Currently, August is the cheapest month in which you can book a flight from Missouri to Florida Keys (average of $328). Flying from Missouri to Florida Keys in March is currently the most expensive (average of $510). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Missouri to Florida Keys

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Missouri to Florida Keys

Discover the top 3 airlines that operate flights from Missouri to Florida Keys. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$189Average$417FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$237Average$450FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$258Average$508FlexibilityNo cancel feeOn-time69%
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