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$55+ Cheap flights from Mississippi to Florida Keys

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/1. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — EYW
Feb 25 — Mar 41
Tue 2/25
Tue 3/4
1 adult, Economy
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Cheap flight deals from Mississippi to Florida Keys

Keep the following information in mind while searching for Mississippi to Florida Keys flight deals. Data was last updated February 20, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$199
(Mytrip)

One-way from

$55
(Cheapflightsfares)

Popular in

June

Cheapest in

September

Average price

$497
Provider with most accurate pricing for Jackson-Evers Intl-Miami flight deals.
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Provider most trusted by Cheapflights users for Jackson-Evers Intl-Miami flights.
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From Mississippi to Florida Keys
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One-way flight from Mississippi to Florida Keys
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Highest demand for flights based on searches. 13% potential increase in price ($71 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($10 potential savings vs. average RT price).
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Average for round-trip flights in February 2025
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Find flight deals from Mississippi to Florida Keys

Cheapest flights from Mississippi to Florida Keys
Explore the most affordable flight options available from Mississippi to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 20, 2025.

This Mytrip deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/102:35 pmMEM - MIA
2 stops29h 05mSpirit Airlines
Fri 3/1410:25 pmMIA - MEM
1 stop15h 55mSpirit Airlines
Deal found 2/20$201
This CheapOair deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/137:53 pmMEM - MIA
1 stop8h 23mMultiple Airlines
Tue 3/187:15 amMIA - MEM
1 stop12h 52mMultiple Airlines
Deal found 2/20$202
This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/186:00 amMEM - MIA
1 stop3h 55mDelta
Tue 3/257:10 amMIA - MEM
1 stop4h 54mDelta
Deal found 2/20$209
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/186:52 pmMEM - MIA
1 stop4h 50mAmerican Airlines
Tue 3/2510:21 pmMIA - MEM
Nonstop2h 35mAmerican Airlines
Deal found 2/20$218
This Frontier deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/67:38 pmMEM - MIA
1 stop8h 43mFrontier
Sun 4/136:30 amMIA - MEM
1 stop13h 09mFrontier
Deal found 2/20$220
This Mytrip deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/248:16 pmMEM - EYW
1 stop12h 01mMultiple Airlines
Sat 3/293:15 pmEYW - MEM
1 stop17h 17mMultiple Airlines
Deal found 2/20$247
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/195:45 pmBTR - MIA
1 stop6h 00mDelta
Wed 3/264:47 pmMIA - BTR
1 stop6h 35mDelta
Deal found 2/19$249
This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/264:40 pmGPT - MIA
1 stop5h 57mDelta
Tue 4/298:10 amMIA - GPT
1 stop5h 02mDelta
Deal found 2/20$249
This United Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/92:10 pmBTR - MIA
1 stop5h 24mUnited Airlines
Sun 5/116:20 amMIA - BTR
1 stop5h 58mUnited Airlines
Deal found 2/20$250
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/129:44 amMEM - EYW
1 stop4h 27mAmerican Airlines
Wed 11/192:00 pmEYW - MEM
2 stops10h 28mAmerican Airlines
Deal found 2/20$254
This Mytrip deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/68:41 pmMEM - EYW
1 stop11h 20mAllegiant Air
Sun 4/139:03 amEYW - MEM
1 stop11h 58mAllegiant Air
Deal found 2/20$259
This Mytrip deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/76:32 pmGPT - MIA
2 stops24h 08mMultiple Airlines
Sun 3/95:30 amMIA - GPT
2 stops13h 38mMultiple Airlines
Deal found 2/18$271

Find flights from Mississippi to Florida Keys within your budget

Customize your flight search to find flights from Mississippi to Florida Keys that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.

Fly from

Mississippi

Fly to

Florida Keys

Route

Depart

Return

Price

MemphisMiami

MEM - MIA

MEMMIA

Memphis

Fri 3/7

2:35 pm-8:33 am

1 stop16h 58m

Miami

Tue 3/11

5:11 pm-1:20 pm

2 stops21h 09m

$199

MemphisMiami

MEM - MIA

MEMMIA

Memphis

Tue 3/18

8:02 pm-6:10 am

1 stop9h 08m

Miami

Thu 3/20

6:25 am-6:53 pm

1 stop13h 28m

$207

MemphisMiami

MEM - MIA

MEMMIA

Memphis

Wed 4/16

6:11 pm-9:30 pm

Nonstop2h 19m

Miami

Tue 4/22

3:45 pm-5:17 pm

Nonstop2h 32m

$208

MemphisMiami

MEM - MIA

MEMMIA

Memphis

Wed 3/19

2:45 pm-10:50 pm

1 stop7h 05m

Miami

Tue 3/25

5:55 pm-11:10 pm

1 stop6h 15m

$209

MemphisMiami

MEM - MIA

MEMMIA

Memphis

Sun 4/6

7:38 pm-5:21 am

1 stop8h 43m

Miami

Sun 4/13

6:30 am-6:39 pm

1 stop13h 09m

$220

MemphisKey West

MEM - EYW

MEMEYW

Memphis

Mon 3/24

8:16 pm-9:17 am

1 stop12h 01m

Key West

Sat 3/29

3:15 pm-7:32 am

1 stop17h 17m

$247

MemphisMiami

MEM - MIA

MEMMIA

Memphis

Sat 4/26

6:00 am-1:50 pm

1 stop6h 50m

Miami

Tue 4/29

6:00 am-9:28 am

1 stop4h 28m

$248

Baton RougeMiami

BTR - MIA

BTRMIA

Baton Rouge Ryan

Wed 3/19

5:45 pm-12:45 am

1 stop6h 00m

Miami

Wed 3/26

4:47 pm-10:22 pm

1 stop6h 35m

$249

GulfportMiami

GPT - MIA

GPTMIA

Gulfport Biloxi Regional

Sat 4/26

4:40 pm-11:37 pm

1 stop5h 57m

Miami

Tue 4/29

8:10 am-12:12 pm

1 stop5h 02m

$249

Baton RougeMiami

BTR - MIA

BTRMIA

Baton Rouge Ryan

Fri 5/9

2:10 pm-8:34 pm

1 stop5h 24m

Miami

Sun 5/11

6:20 am-11:18 am

1 stop5h 58m

$250

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/19

Showing 1-10 of 53 results
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Best time to book a flight from Mississippi to Florida Keys

Have a flexible travel schedule? Discover the best time to fly to Florida Keys from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Mississippi to Florida Keys

Get recent, data-driven insights about flights from Mississippi to Florida Keys including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Mississippi to Florida Keys?

Currently, August is the cheapest month in which you can book a flight from Mississippi to Florida Keys (average of $328). Flying from Mississippi to Florida Keys in March is currently the most expensive (average of $510). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Rainfall in Florida Keys by month

Plan your trip to Florida Keys by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Florida Keys ranges from 1.6 - 9.9 inches per month. September is typically the wettest month, when rainfall can reach 9.9 in. January is typically the driest time to visit Florida Keys when rainfall is around 1.6 in.

Temperature in Florida Keys by month

Plan your trip to Florida Keys by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Florida Keys, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 84.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 68.0 F).

Reviews of airlines servicing Florida Keys

Get insights into the airlines that provide service to Florida Keys. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florida Keys. Reviews last updated February 20, 2025.
Read through reviews of airlines operating flights from Mississippi to Florida Keys, such as Southwest, Delta and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
4,411 reviews

Crew

8.7

Overall

8.1

Boarding

8.2

Comfort

8.1

Entertainment

7.6

Food

7.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Southwest
8.1
Very good
4,411 reviews
Southwest
8.1
Very good
4,411 reviews

Crew

8.7

Overall

8.1

Boarding

8.2

Comfort

8.1

Entertainment

7.6

Food

7.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Delta
8.0
Very good
8,220 reviews
Southwest
8.1
Very good
4,411 reviews

Crew

8.7

Overall

8.1

Boarding

8.2

Comfort

8.1

Entertainment

7.6

Food

7.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

United Airlines
7.4
Good
8,766 reviews
Southwest
8.1
Very good
4,411 reviews

Crew

8.7

Overall

8.1

Boarding

8.2

Comfort

8.1

Entertainment

7.6

Food

7.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Allegiant Air
7.3
Good
765 reviews
Southwest
8.1
Very good
4,411 reviews

Crew

8.7

Overall

8.1

Boarding

8.2

Comfort

8.1

Entertainment

7.6

Food

7.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

American Airlines
7.2
Good
10,000 reviews
Southwest
8.1
Very good
4,411 reviews

Crew

8.7

Overall

8.1

Boarding

8.2

Comfort

8.1

Entertainment

7.6

Food

7.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Related info for your journey

Find useful and relevant information for your journey from Mississippi to Florida Keys. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Mississippi to Florida Keys one-way?

    $55 is the cheapest one-way deal found within the past few days, from Frontier. You may also be able to find cheap deals on Spirit Airlines and Southwest, with prices starting from $86 and $100, respectively.

  • Can I find deals for flights from Mississippi to Florida Keys that include hotel bookings?

    Yes. In addition to deals on Mississippi to Florida Keys flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to Florida Keys?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to Florida Keys.

  • Can I find deals for business class flights from Mississippi to Florida Keys?

    Yes. Cheapflights offers flight deals from Mississippi to Florida Keys by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mississippi to Florida Keys?

    Currently, August is the cheapest month in which you can book a flight from Mississippi to Florida Keys (average of $328). Flying from Mississippi to Florida Keys in March is currently the most expensive (average of $510). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Mississippi to Florida Keys

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Mississippi to Florida Keys

Discover the top 2 airlines that operate flights from Mississippi to Florida Keys. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$238Average$490FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$288Average$541FlexibilityNo cancel feeOn-time71%
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