HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Florida Keys

$85+ Cheap flights from Louisville (SDF) to Florida Keys

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/24. Fares are subject to change and may not be available on all flights or dates of travel.
SDF — EYW
Feb 25 — Mar 41
Tue 2/25
Tue 3/4
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Louisville to Florida Keys with Cheapflights

1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”
2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.
3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Louisville to Florida Keys

Keep the following information in mind while searching for Louisville to Florida Keys flight deals. Data was last updated February 20, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$189
(American Airlines)

One-way from

$85
(Mytrip)

Popular in

March

Cheapest in

April

Average price

$317
Provider with most accurate pricing for Louisville Intl-Miami flight deals.
Search Deals
Provider most trusted by Cheapflights users for Louisville Intl-Miami flights.
Search Deals
From Louisville Intl to Florida Keys
Search Deals
One-way flight from Louisville Intl to Florida Keys
Search Deals
High demand for flights, 1% potential price rise
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($4 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2025
Search Deals

Find flight deals from Louisville to Florida Keys

Cheapest flights from Louisville to Florida Keys
Explore the most affordable flight options available from Louisville to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 20, 2025.

This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/196:16 amSDF - MIA
Nonstop2h 44mAmerican Airlines
Wed 3/269:35 pmMIA - SDF
Nonstop2h 43mAmerican Airlines
Deal found 2/19$189
This Southwest deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/258:55 amSDF - MIA
1 stop8h 10mSouthwest
Wed 3/268:40 amMIA - SDF
1 stop6h 10mSouthwest
Deal found 2/18$199
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/124:59 pmSDF - MIA
1 stop4h 40mDelta
Tue 3/257:10 amMIA - SDF
1 stop4h 52mDelta
Deal found 2/19$209
This Mytrip deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/195:33 pmSDF - MIA
3 stops22h 01mSpirit Airlines
Wed 3/2610:17 amMIA - SDF
2 stops36h 41mSpirit Airlines
Deal found 2/19$214
This Mytrip deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/289:30 pmSDF - MIA
2 stops25h 59mMultiple Airlines
Fri 3/79:43 amMIA - SDF
1 stop5h 02mMultiple Airlines
Deal found 2/20$231
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/91:04 pmSDF - EYW
1 stop4h 11mDelta
Wed 4/166:13 pmEYW - SDF
1 stop5h 46mDelta
Deal found 2/19$259
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/911:03 amSDF - EYW
2 stops7h 52mAmerican Airlines
Wed 4/167:29 pmEYW - SDF
1 stop4h 16mAmerican Airlines
Deal found 2/19$264
This Mytrip deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/78:46 pmSDF - EYW
1 stop18h 00mMultiple Airlines
Tue 3/112:34 pmEYW - SDF
2 stops27h 47mMultiple Airlines
Deal found 2/20$287
This United Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/77:02 amSDF - EYW
1 stop8h 01mUnited Airlines
Mon 3/1012:45 pmEYW - SDF
1 stop6h 53mUnited Airlines
Deal found 2/20$290
This United Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/186:00 amSDF - MIA
2 stops11h 34mUnited Airlines
Wed 3/191:05 pmMIA - SDF
1 stop8h 42mUnited Airlines
Deal found 2/20$293

Find flights from Louisville to Florida Keys within your budget

Customize your flight search to find flights from Louisville to Florida Keys that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.

Fly from

Louisville

Fly to

Florida Keys

Route

Depart

Return

Price

LouisvilleMiami

SDF - MIA

SDFMIA

Louisville Intl

Wed 3/19

6:16 am-9:00 am

Nonstop2h 44m

Miami

Wed 3/26

9:35 pm-12:18 am

Nonstop2h 43m

$189

LouisvilleMiami

SDF - MIA

SDFMIA

Louisville Intl

Tue 3/25

8:55 am-5:05 pm

1 stop8h 10m

Miami

Wed 3/26

8:40 am-2:50 pm

1 stop6h 10m

$199

LouisvilleMiami

SDF - MIA

SDFMIA

Louisville Intl

Wed 3/12

4:59 pm-9:39 pm

1 stop4h 40m

Miami

Tue 3/25

7:10 am-12:02 pm

1 stop4h 52m

$209

LouisvilleMiami

SDF - MIA

SDFMIA

Louisville Intl

Wed 3/19

5:33 pm-3:34 pm

3 stops22h 01m

Miami

Wed 3/26

10:17 am-10:58 pm

2 stops36h 41m

$214

LouisvilleMiami

SDF - MIA

SDFMIA

Louisville Intl

Fri 2/28

9:30 pm-11:29 pm

2 stops25h 59m

Miami

Fri 3/7

9:43 am-2:45 pm

1 stop5h 02m

$231

LouisvilleKey West

SDF - EYW

SDFEYW

Louisville Intl

Wed 4/9

1:04 pm-5:15 pm

1 stop4h 11m

Key West

Wed 4/16

6:13 pm-11:59 pm

1 stop5h 46m

$259

LouisvilleKey West

SDF - EYW

SDFEYW

Louisville Intl

Wed 4/9

12:14 pm-6:55 pm

1 stop6h 41m

Key West

Wed 4/16

1:39 pm-10:15 pm

2 stops8h 36m

$264

LouisvilleKey West

SDF - EYW

SDFEYW

Louisville Intl

Fri 3/7

8:46 pm-2:46 pm

1 stop18h 00m

Key West

Tue 3/11

2:34 pm-6:21 pm

2 stops27h 47m

$287

LouisvilleKey West

SDF - EYW

SDFEYW

Louisville Intl

Fri 3/7

7:02 am-3:03 pm

1 stop8h 01m

Key West

Tue 3/11

12:45 pm-7:38 pm

1 stop6h 53m

$290

LouisvilleMiami

SDF - MIA

SDFMIA

Louisville Intl

Tue 3/18

6:00 am-5:34 pm

2 stops11h 34m

Miami

Wed 3/19

1:05 pm-9:47 pm

1 stop8h 42m

$293

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/19

Showing 1-10 of 16 results
1
2

Best time to book a flight from Louisville to Florida Keys

Have a flexible travel schedule? Discover the best time to fly to Florida Keys from Louisville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Louisville to Florida Keys

Get recent, data-driven insights about flights from Louisville to Florida Keys including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Louisville to Florida Keys?

Currently, August is the cheapest month in which you can book a flight from Louisville to Florida Keys (average of $328). Flying from Louisville to Florida Keys in March is currently the most expensive (average of $510). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SDF to EOA?

Find hourly flight availability from Louisville to Florida Keys. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 20, 2025.

When flying from Louisville to Florida Keys, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Florida Keys by month

Plan your trip to Florida Keys by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Florida Keys ranges from 1.6 - 9.9 inches per month. September is typically the wettest month, when rainfall can reach 9.9 in. January is typically the driest time to visit Florida Keys when rainfall is around 1.6 in.

Temperature in Florida Keys by month

Plan your trip to Florida Keys by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Florida Keys, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 84.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 68.0 F).

Reviews of airlines servicing Florida Keys

Get insights into the airlines that provide service to Florida Keys. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florida Keys. Reviews last updated February 20, 2025.
See what other customers who have flown with Southwest, Delta and United Airlines from Louisville to Florida Keys have to say. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
4,411 reviews

Entertainment

7.6

Boarding

8.2

Overall

8.1

Comfort

8.1

Food

7.1

Crew

8.7

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Southwest
8.1
Very good
4,411 reviews
Southwest
8.1
Very good
4,411 reviews

Entertainment

7.6

Boarding

8.2

Overall

8.1

Comfort

8.1

Food

7.1

Crew

8.7

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Delta
8.0
Very good
8,219 reviews
Southwest
8.1
Very good
4,411 reviews

Entertainment

7.6

Boarding

8.2

Overall

8.1

Comfort

8.1

Food

7.1

Crew

8.7

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

United Airlines
7.4
Good
8,765 reviews
Southwest
8.1
Very good
4,411 reviews

Entertainment

7.6

Boarding

8.2

Overall

8.1

Comfort

8.1

Food

7.1

Crew

8.7

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

American Airlines
7.2
Good
10,000 reviews
Southwest
8.1
Very good
4,411 reviews

Entertainment

7.6

Boarding

8.2

Overall

8.1

Comfort

8.1

Food

7.1

Crew

8.7

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Spirit Airlines
6.3
Okay
8,013 reviews
Southwest
8.1
Very good
4,411 reviews

Entertainment

7.6

Boarding

8.2

Overall

8.1

Comfort

8.1

Food

7.1

Crew

8.7

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Related info for your journey

Find useful and relevant information for your journey from Louisville to Florida Keys. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Louisville to Florida Keys?

    Located just 5.3 mi from the city center, Louisville Intl (SDF) is the airport most travelers will use when flying to Florida Keys from Louisville.

  • What are the cheapest airlines to fly from Louisville to Florida Keys one-way?

    To fly one-way, consider booking your trip with Spirit Airlines, which is currently one of the cheapest options available, starting at $85. American Airlines flights start at $99 while deals on Southwest start at $100 one-way.

  • Can I find deals for flights from Louisville to Florida Keys that include hotel bookings?

    Yes. In addition to deals on Louisville to Florida Keys flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Louisville to Florida Keys?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Louisville to Florida Keys.

  • Can I find deals for business class flights from Louisville to Florida Keys?

    Yes. Cheapflights offers flight deals from Louisville to Florida Keys by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Louisville to Florida Keys?

    Currently, August is the cheapest month in which you can book a flight from Louisville to Florida Keys (average of $328). Flying from Louisville to Florida Keys in March is currently the most expensive (average of $510). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Louisville to Florida Keys

See prices for flight routes from nearby airports that may be better suited for you.
Cincinnati to Orlando flights
Cincinnati to Tampa flights
Cincinnati to Fort Lauderdale flights
Nashville to Orlando flights
Cincinnati to Fort Myers flights
Nashville to Miami flights
Nashville to Fort Lauderdale flights
Cincinnati to Orlando Sanford Intl flights
Cincinnati to St Petersburg flights
Cincinnati to Sarasota flights
Nashville to Tampa flights
Louisville to Orlando flights
Cincinnati to Miami flights
Louisville to Fort Lauderdale flights
Louisville to Miami flights
Cincinnati to Pensacola flights
Louisville to Tampa flights
Lexington to Orlando flights
Lexington to Tampa flights
Knoxville to Fort Lauderdale flights
Nashville to West Palm Beach flights
Cincinnati to Valparaiso flights
Knoxville to Orlando Sanford Intl flights
Nashville to Jacksonville flights
Cincinnati to Panama City flights
Lexington to Sarasota flights
Knoxville to Miami flights
Lexington to Miami flights
Knoxville to Tampa flights
Nashville to Fort Myers flights
Louisville to Fort Myers flights
Louisville to Pensacola flights
Nashville to Sarasota flights
Lexington to Pensacola flights
Cincinnati to West Palm Beach flights
Cincinnati to Punta Gorda flights
Cincinnati to Key West flights
Cincinnati to Daytona Beach flights
Knoxville to Orlando flights
Nashville to Pensacola flights
Louisville to West Palm Beach flights
Lexington to West Palm Beach flights
Lexington to Fort Myers flights
Louisville to Sarasota flights
Nashville to Key West flights
Lexington to Jacksonville flights
Knoxville to St Petersburg flights
Lexington to Orlando Sanford Intl flights
Cincinnati to Jacksonville flights
Louisville to Jacksonville flights

Top 2 airlines flying from Louisville to Florida Keys

Discover the top 2 airlines that operate flights from Louisville to Florida Keys. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$218Average$398FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$250Average$396FlexibilityNo cancel feeOn-time71%
100% Free
Cheapflights is completely free to use, so you can start saving the moment you arrive.
Book with Flexibility
Our users can plan ahead with confidence and find flights with no change fees
Travel Smart
Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.