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$108+ Cheap flights from Knoxville (TYS) to Florida Keys

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/15. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — EYW
Feb 4 — Feb 111
Tue 2/4
Tue 2/11
1 adult, Economy
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Cheap flight deals from Knoxville to Florida Keys

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Florida Keys (zzEOA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 30, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$214
(Mytrip)

One-way from

$108
(Mytrip)

Popular in

March

Cheapest in

August

Average price

$384
Provider with most accurate pricing for Knoxville McGhee Tyson-Miami flight deals.
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Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Miami flights.
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From Knoxville McGhee Tyson to Florida Keys
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One-way flight from Knoxville McGhee Tyson to Florida Keys
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Highest demand for flights based on searches. 3% potential increase in price ($14 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
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Average for round-trip flights in January 2025
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Find flight deals from Knoxville to Florida Keys

Cheapest flights from Knoxville to Florida Keys
Explore the most affordable flight options available from Knoxville to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 30, 2025.

This Mytrip deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/38:15 amTYS - MIA
1 stop10h 10mMultiple Airlines
Tue 3/47:55 pmMIA - TYS
1 stop16h 05mMultiple Airlines
Deal found 1/29$214
This American Airlines deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/192:43 pmTYS - MIA
1 stop6h 54mAmerican Airlines
Wed 2/268:57 pmMIA - TYS
Nonstop2h 08mAmerican Airlines
Deal found 1/30$216
This Mytrip deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/66:44 pmTYS - EYW
1 stop14h 18mAllegiant Air
Wed 3/123:06 pmEYW - TYS
1 stop5h 33mAllegiant Air
Deal found 1/29$220
This American Airlines deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/62:38 pmTYS - EYW
1 stop4h 12mAmerican Airlines
Wed 3/123:57 pmEYW - TYS
2 stops8h 06mAmerican Airlines
Deal found 1/29$228
This Delta deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/37:17 pmTYS - MIA
1 stop5h 34mDelta
Tue 3/116:00 amMIA - TYS
1 stop5h 14mDelta
Deal found 1/28$259
This Delta deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/204:00 pmTYS - EYW
1 stop3h 46mDelta
Sat 8/232:35 pmEYW - TYS
1 stop3h 42mDelta
Deal found 1/29$269
This United Airlines deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/197:00 amTYS - MIA
2 stops12h 05mUnited Airlines
Wed 2/267:00 amMIA - TYS
1 stop6h 15mUnited Airlines
Deal found 1/30$286
This Booking.com deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/64:19 pmTYS - MIA
1 stop9h 35mFrontier
Sat 2/86:14 pmMIA - TYS
1 stop21h 05mFrontier
Deal found 1/30$320
This Mytrip deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/612:53 pmTYS - EYW
3 stops27h 25mMultiple Airlines
Wed 3/123:06 pmEYW - TYS
1 stop5h 33mMultiple Airlines
Deal found 1/29$352
This United Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/15:45 amTYS - EYW
1 stop5h 54mUnited Airlines
Mon 2/33:50 pmEYW - TYS
1 stop6h 51mUnited Airlines
Deal found 1/28$419

Find flights from Knoxville to Florida Keys within your budget

Customize your flight search to find flights from Knoxville to Florida Keys that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 30, 2025.

Fly from

Any airport

Fly to

Any airport

Route

Depart

Return

Price

KnoxvilleMiami

TYS - MIA

TYSMIA

Knoxville McGhee Tyson

Wed 2/19

2:43 pm-9:37 pm

1 stop6h 54m

Miami

Wed 2/26

8:57 pm-11:05 pm

Nonstop2h 08m

$216

KnoxvilleKey West

TYS - EYW

TYSEYW

Knoxville McGhee Tyson

Thu 3/6

6:44 pm-9:02 am

1 stop14h 18m

Key West

Wed 3/12

3:06 pm-8:39 pm

1 stop5h 33m

$220

KnoxvilleKey West

TYS - EYW

TYSEYW

Knoxville McGhee Tyson

Thu 3/6

2:38 pm-6:50 pm

1 stop4h 12m

Key West

Wed 3/12

3:57 pm-12:03 am

2 stops8h 06m

$228

KnoxvilleMiami

TYS - MIA

TYSMIA

Knoxville McGhee Tyson

Thu 3/6

6:20 am-7:40 pm

1 stop13h 20m

Miami

Tue 3/11

10:25 pm-7:52 pm

2 stops21h 27m

$233

KnoxvilleMiami

TYS - MIA

TYSMIA

Knoxville McGhee Tyson

Wed 2/19

7:00 am-7:05 pm

2 stops12h 05m

Miami

Wed 2/26

7:00 am-1:15 pm

1 stop6h 15m

$286

KnoxvilleKey West

TYS - EYW

TYSEYW

Knoxville McGhee Tyson

Tue 5/13

4:00 pm-7:44 pm

1 stop3h 44m

Key West

Wed 5/21

7:00 am-11:05 am

1 stop4h 05m

$319

KnoxvilleMiami

TYS - MIA

TYSMIA

Knoxville McGhee Tyson

Sat 2/22

5:45 am-9:23 am

1 stop3h 38m

Miami

Tue 2/25

8:10 am-1:27 pm

1 stop5h 17m

$323

KnoxvilleKey West

TYS - EYW

TYSEYW

Knoxville McGhee Tyson

Thu 3/6

12:53 pm-4:18 pm

3 stops27h 25m

Key West

Wed 3/12

3:06 pm-8:39 pm

1 stop5h 33m

$352

KnoxvilleKey West

TYS - EYW

TYSEYW

Knoxville McGhee Tyson

Sun 3/2

7:05 am-4:09 pm

1 stop9h 04m

Key West

Wed 3/5

10:55 am-11:00 pm

2 stops12h 05m

$476

KnoxvilleMiami

TYS - MIA

TYSMIA

Knoxville McGhee Tyson

Thu 3/20

4:23 pm-5:16 am

1 stop12h 53m

Miami

Sun 3/23

6:25 am-3:43 pm

1 stop9h 18m

$710

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/30

Showing 1-10 of 15 results
1
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Best time to book a flight from Knoxville to Florida Keys

Have a flexible travel schedule? Discover the best time to fly to Florida Keys from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Knoxville to Florida Keys

Get recent, data-driven insights about flights from Knoxville to Florida Keys including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Knoxville to Florida Keys?

Currently, August is the cheapest month in which you can book a flight from Knoxville to Florida Keys (average of $328). Flying from Knoxville to Florida Keys in March is currently the most expensive (average of $526). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to EOA?

Find hourly flight availability from Knoxville to Florida Keys. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 30, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Knoxville to Florida Keys as you normally would.

Rainfall in Florida Keys by month

Plan your trip to Florida Keys by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Florida Keys ranges from 1.6 - 9.9 inches per month. September is typically the wettest month, when rainfall can reach 9.9 in. January is typically the driest time to visit Florida Keys when rainfall is around 1.6 in.

Temperature in Florida Keys by month

Plan your trip to Florida Keys by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Florida Keys, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 84.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 68.0 F).

Reviews of airlines servicing Florida Keys

Get insights into the airlines that provide service to Florida Keys. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florida Keys. Reviews last updated January 30, 2025.
Read through reviews of airlines operating flights from Knoxville to Florida Keys, such as Delta, United Airlines and Allegiant Air. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
8,450 reviews

Comfort

8.0

Entertainment

7.9

Overall

8.0

Boarding

8.2

Food

7.3

Crew

8.5

Reviews

1 / 20

2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.

Delta
8.0
Very good
8,450 reviews
Delta
8.0
Very good
8,450 reviews

Comfort

8.0

Entertainment

7.9

Overall

8.0

Boarding

8.2

Food

7.3

Crew

8.5

Reviews

1 / 20

2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.

United Airlines
7.4
Good
8,906 reviews
Delta
8.0
Very good
8,450 reviews

Comfort

8.0

Entertainment

7.9

Overall

8.0

Boarding

8.2

Food

7.3

Crew

8.5

Reviews

1 / 20

2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.

Allegiant Air
7.3
Good
790 reviews
Delta
8.0
Very good
8,450 reviews

Comfort

8.0

Entertainment

7.9

Overall

8.0

Boarding

8.2

Food

7.3

Crew

8.5

Reviews

1 / 20

2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.

American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
8,450 reviews

Comfort

8.0

Entertainment

7.9

Overall

8.0

Boarding

8.2

Food

7.3

Crew

8.5

Reviews

1 / 20

2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.

Frontier
6.0
Okay
3,424 reviews
Delta
8.0
Very good
8,450 reviews

Comfort

8.0

Entertainment

7.9

Overall

8.0

Boarding

8.2

Food

7.3

Crew

8.5

Reviews

1 / 20

2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Florida Keys. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Florida Keys?

    Most people fly from Knoxville McGhee Tyson (TYS) if they book a flight from Knoxville to Florida Keys. Knoxville McGhee Tyson is conveniently located just 11.3 mi from Knoxville’s city center.

  • What are the cheapest airlines to fly from Knoxville to Florida Keys one-way?

    $108 is the cheapest one-way deal found within the past few days, from Allegiant Air. You may also be able to find cheap deals on Delta and American Airlines, with prices starting from $164 and $212, respectively.

  • Can I find deals for flights from Knoxville to Florida Keys that include hotel bookings?

    Yes. In addition to deals on Knoxville to Florida Keys flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Florida Keys?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Florida Keys.

  • Can I find deals for business class flights from Knoxville to Florida Keys?

    Yes. Cheapflights offers flight deals from Knoxville to Florida Keys by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Florida Keys?

    Currently, August is the cheapest month in which you can book a flight from Knoxville to Florida Keys (average of $328). Flying from Knoxville to Florida Keys in March is currently the most expensive (average of $526). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 3 airlines flying from Knoxville to Florida Keys

Discover the top 3 airlines that operate flights from Knoxville to Florida Keys. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$96Average$289FlexibilityNo cancel feeOn-time88%
DeltaCheapest$208Average$481FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$248Average$548FlexibilityNo cancel feeOn-time71%
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