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Florida Keys

$55+ Cheap flights from Iowa to Florida Keys

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/12. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — EYW
Feb 28 — Mar 71
Fri 2/28
Fri 3/7
1 adult, Economy
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Cheap flight deals from Iowa to Florida Keys

Keep the following information in mind while searching for Iowa to Florida Keys flight deals. Data was last updated February 23, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$130
(Frontier)

One-way from

$55
(Frontier)

Popular in

December

Cheapest in

May

Average price

$447
Provider with most accurate pricing for Des Moines-Miami flight deals.
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From Iowa to Florida Keys
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One-way flight from Iowa to Florida Keys
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Highest demand for flights based on searches. 3% potential increase in price ($13 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($9 potential savings vs. average RT price).
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Average for round-trip flights in February 2025
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Find flight deals from Iowa to Florida Keys

Cheapest flights from Iowa to Florida Keys
Explore the most affordable flight options available from Iowa to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 23, 2025.

This Frontier deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/268:14 pmCID - MIA
1 stop8h 07mFrontier
Tue 4/296:00 amMIA - CID
1 stop14h 14mFrontier
Deal found 2/22$130
This American Airlines deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/259:55 amOMA - EYW
1 stop5h 41mAmerican Airlines
Wed 4/27:55 amEYW - OMA
1 stop6h 58mAmerican Airlines
Deal found 2/23$209
This American Airlines deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/25:30 amCID - EYW
2 stops10h 55mAmerican Airlines
Wed 4/93:06 pmEYW - CID
1 stop7h 53mAmerican Airlines
Deal found 2/22$214
This Delta deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/255:30 amOMA - EYW
1 stop5h 05mDelta
Wed 4/21:30 pmEYW - OMA
1 stop8h 01mDelta
Deal found 2/22$217
This Mytrip deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/93:04 pmMLI - EYW
1 stop16h 58mAllegiant Air
Thu 3/138:53 amEYW - MLI
1 stop6h 26mAllegiant Air
Deal found 2/22$236
This Mytrip deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/54:28 pmDSM - EYW
1 stop16h 00mAllegiant Air
Thu 4/109:03 amEYW - DSM
1 stop8h 06mAllegiant Air
Deal found 2/22$253
This Mytrip deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/56:53 pmCID - EYW
1 stop12h 10mAllegiant Air
Thu 4/109:03 amEYW - CID
1 stop10h 51mAllegiant Air
Deal found 2/22$257
This Delta deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/85:45 amDSM - MIA
1 stop6h 56mDelta
Tue 4/1511:25 amMIA - DSM
1 stop8h 49mDelta
Deal found 2/22$257
This Frontier deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/128:17 pmDSM - MIA
1 stop7h 59mFrontier
Sun 3/166:25 amMIA - DSM
1 stop14h 20mFrontier
Deal found 2/22$260
This Mytrip deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/101:32 pmDSM - MIA
2 stops17h 57mMultiple Airlines
Fri 3/145:30 amMIA - DSM
2 stops37h 10mMultiple Airlines
Deal found 2/22$264
This Delta deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/305:45 amCID - EYW
1 stop6h 24mDelta
Thu 9/46:00 pmEYW - CID
1 stop4h 50mDelta
Deal found 2/22$269
This American Airlines deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/51:59 pmDSM - EYW
1 stop5h 12mAmerican Airlines
Thu 4/108:00 amEYW - DSM
1 stop6h 13mAmerican Airlines
Deal found 2/22$269

Find flights from Iowa to Florida Keys within your budget

Customize your flight search to find flights from Iowa to Florida Keys that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 23, 2025.

Fly from

Iowa

Fly to

Florida Keys

Route

Depart

Return

Price

Cedar RapidsMiami

CID - MIA

CIDMIA

Cedar Rapids

Sat 4/26

8:14 pm-5:21 am

1 stop8h 07m

Miami

Tue 4/29

6:00 am-7:14 pm

1 stop14h 14m

$130

OmahaKey West

OMA - EYW

OMAEYW

Omaha Eppley Airfield

Tue 3/25

9:55 am-4:36 pm

1 stop5h 41m

Key West

Wed 4/2

7:55 am-1:53 pm

1 stop6h 58m

$209

Cedar RapidsKey West

CID - EYW

CIDEYW

Cedar Rapids

Wed 4/2

5:30 am-5:25 pm

2 stops10h 55m

Key West

Wed 4/9

3:06 pm-9:59 pm

1 stop7h 53m

$214

OmahaKey West

OMA - EYW

OMAEYW

Omaha Eppley Airfield

Tue 3/25

5:30 am-11:35 am

1 stop5h 05m

Key West

Wed 4/2

1:30 pm-8:31 pm

1 stop8h 01m

$217

MolineKey West

MLI - EYW

MLIEYW

Moline Quad-City

Sun 3/9

3:04 pm-9:02 am

1 stop16h 58m

Key West

Thu 3/13

8:53 am-2:19 pm

1 stop6h 26m

$236

Des MoinesKey West

DSM - EYW

DSMEYW

Des Moines

Sat 4/5

4:28 pm-9:28 am

1 stop16h 00m

Key West

Thu 4/10

9:03 am-4:09 pm

1 stop8h 06m

$253

Des MoinesMiami

DSM - MIA

DSMMIA

Des Moines

Tue 4/8

5:45 am-1:41 pm

1 stop6h 56m

Miami

Tue 4/15

11:25 am-7:14 pm

1 stop8h 49m

$257

Cedar RapidsKey West

CID - EYW

CIDEYW

Cedar Rapids

Sat 4/5

6:53 pm-8:03 am

1 stop12h 10m

Key West

Thu 4/10

9:03 am-6:54 pm

1 stop10h 51m

$257

Des MoinesMiami

DSM - MIA

DSMMIA

Des Moines

Wed 3/12

8:17 pm-5:16 am

1 stop7h 59m

Miami

Sun 3/16

6:25 am-7:45 pm

1 stop14h 20m

$260

Des MoinesMiami

DSM - MIA

DSMMIA

Des Moines

Mon 3/10

1:32 pm-8:29 am

2 stops17h 57m

Miami

Fri 3/14

5:30 am-5:40 pm

2 stops37h 10m

$264

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/23

Showing 1-10 of 56 results
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Best time to book a flight from Iowa to Florida Keys

Have a flexible travel schedule? Discover the best time to fly to Florida Keys from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Iowa to Florida Keys

Get recent, data-driven insights about flights from Iowa to Florida Keys including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Iowa to Florida Keys?

Currently, August is the cheapest month in which you can book a flight from Iowa to Florida Keys (average of $328). Flying from Iowa to Florida Keys in March is currently the most expensive (average of $510). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IA to EOA?

Find hourly flight availability from Iowa to Florida Keys. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 23, 2025.

When flying from Iowa to Florida Keys, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Florida Keys by month

Plan your trip to Florida Keys by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Florida Keys ranges from 1.6 - 9.9 inches per month. September is typically the wettest month, when rainfall can reach 9.9 in. January is typically the driest time to visit Florida Keys when rainfall is around 1.6 in.

Temperature in Florida Keys by month

Plan your trip to Florida Keys by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Florida Keys, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 84.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 68.0 F).

Reviews of airlines servicing Florida Keys

Get insights into the airlines that provide service to Florida Keys. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florida Keys. Reviews last updated February 23, 2025.
See what other customers who have flown with Southwest, Alaska Airlines and Delta from Iowa to Florida Keys have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
4,387 reviews

Overall

8.1

Boarding

8.2

Food

7.1

Comfort

8.1

Crew

8.7

Entertainment

7.6

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Southwest
8.1
Very good
4,387 reviews
Southwest
8.1
Very good
4,387 reviews

Overall

8.1

Boarding

8.2

Food

7.1

Comfort

8.1

Crew

8.7

Entertainment

7.6

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Alaska Airlines
8.0
Very good
9,707 reviews
Southwest
8.1
Very good
4,387 reviews

Overall

8.1

Boarding

8.2

Food

7.1

Comfort

8.1

Crew

8.7

Entertainment

7.6

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Delta
8.0
Very good
8,191 reviews
Southwest
8.1
Very good
4,387 reviews

Overall

8.1

Boarding

8.2

Food

7.1

Comfort

8.1

Crew

8.7

Entertainment

7.6

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

United Airlines
7.4
Good
8,746 reviews
Southwest
8.1
Very good
4,387 reviews

Overall

8.1

Boarding

8.2

Food

7.1

Comfort

8.1

Crew

8.7

Entertainment

7.6

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Allegiant Air
7.3
Good
762 reviews
Southwest
8.1
Very good
4,387 reviews

Overall

8.1

Boarding

8.2

Food

7.1

Comfort

8.1

Crew

8.7

Entertainment

7.6

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Related info for your journey

Find useful and relevant information for your journey from Iowa to Florida Keys. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Iowa to Florida Keys one-way?

    The cheapest airline one-way is Frontier, with whom users have recently found tickets for as low as $55. However, be on the lookout for offers from American Airlines and Delta, as they are both options that can get you from Iowa to Florida Keys for a low price.

  • Can I find deals for flights from Iowa to Florida Keys that include hotel bookings?

    Yes. In addition to deals on Iowa to Florida Keys flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to Florida Keys?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Florida Keys.

  • Can I find deals for business class flights from Iowa to Florida Keys?

    Yes. Cheapflights offers flight deals from Iowa to Florida Keys by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to Florida Keys?

    Currently, August is the cheapest month in which you can book a flight from Iowa to Florida Keys (average of $328). Flying from Iowa to Florida Keys in March is currently the most expensive (average of $510). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Iowa to Florida Keys

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Iowa to Florida Keys

Discover the top 3 airlines that operate flights from Iowa to Florida Keys. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 23, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$243Average$402FlexibilityNo cancel feeOn-time71%
DeltaCheapest$268Average$451FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$288Average$548FlexibilityNo cancel feeOn-time69%
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