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$664+ Cheap flights from Oregon to Florence, SC (FLO)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/15. Fares are subject to change and may not be available on all flights or dates of travel.
PDX — FLO
Jan 11 — Jan 181
Sun 1/11
Sun 1/18
1 adult, Economy
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Cheap flight deals from Oregon to Florence

Cheapest flights from Oregon to Florence
Explore the most affordable flight options available from Oregon to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/1510:15 pmPDX - FLO
1 stop9h 35mAmerican Airlines
Sat 12/2012:51 pmFLO - PDX
2 stops11h 33mAmerican Airlines
Deal found 12/10$664
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/1610:15 pmPDX - FLO
1 stop8h 35mAmerican Airlines
Tue 12/235:15 amFLO - PDX
2 stops11h 57mAmerican Airlines
Deal found 12/10$831

Find flight deals from Oregon to Florence

Keep the following information in mind while searching for Oregon to Florence flight deals. Data was last updated December 12, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
1 star
Provider with most accurate pricing for Portland-Florence flight deals.
Search Deals
Provider most trusted by Cheapflights users for Portland-Florence flights.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Oregon to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
Use the filters below to find and compare flights from Oregon to Florence that are best for you.

Fly from

Oregon

Fly to

Florence

Route

Depart

Return

Price

PortlandFlorence

PDX - FLO

PDXFLO

Portland

Mon 12/15

10:15 pm-10:50 am

1 stop9h 35m

Florence

Sat 12/20

12:51 pm-9:24 pm

2 stops11h 33m

$664

PortlandFlorence

PDX - FLO

PDXFLO

Portland

Tue 12/16

10:15 pm-9:50 am

1 stop8h 35m

Florence

Tue 12/23

5:15 am-2:12 pm

2 stops11h 57m

$831

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/10

Best time to book a flight from Oregon to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Oregon with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Oregon to Florence

What is the cheapest month to book a flight from Oregon to Florence, South Carolina?

Currently, January is the cheapest month in which you can book a flight from Oregon to Florence, South Carolina (average of $164). Flying from Oregon to Florence, South Carolina in December is currently the most expensive (average of $304). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from OR to FLO?

Find hourly flight availability from Oregon to Florence. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 12, 2025.

When flying from Oregon to Florence, South Carolina, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 20% versus a flight at noon.

Related info for your journey

Find useful and relevant information for your journey from Oregon to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Florence from Oregon?

    Florence (FLO) is the airport you will fly into if you book a flight from Oregon to Florence. It is only a 2.3 mi journey from Florence (FLO) to Florence’s city center.

  • How long is the flight from Oregon to Florence, South Carolina?

    American Airlines can get you from Oregon to Florence, South Carolina in just under 9h 35m. Your travel time can differ by up to . The distance between Oregon and Florence, South Carolina is about 2371 mi.

  • Can I find deals for flights from Oregon to Florence that include hotel bookings?

    Yes. In addition to deals on Oregon to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Oregon to Florence?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Oregon to Florence.

  • Can I find deals for business class flights from Oregon to Florence?

    Yes. Cheapflights offers flight deals from Oregon to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Oregon to Florence, South Carolina?

    Currently, January is the cheapest month in which you can book a flight from Oregon to Florence, South Carolina (average of $164). Flying from Oregon to Florence, South Carolina in December is currently the most expensive (average of $304). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Hartsville
Darlington

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