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$395+ Cheap flights from Ohio to Florence, SC (FLO)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/4. Fares are subject to change and may not be available on all flights or dates of travel.
CLE — FLO
Apr 9 — Apr 161
Wed 4/9
Wed 4/16
1 adult, Economy
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Cheap flight deals from Ohio to Florence

Keep the following information in mind while searching for Ohio to Florence flight deals. Data was last updated April 4, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$395
(American Airlines)
Provider with most accurate pricing for Cleveland Hopkins Intl-Florence flight deals.
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Provider most trusted by Cheapflights users for Cleveland Hopkins Intl-Florence flights.
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From Ohio to Florence
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Find flight deals from Ohio to Florence

Cheapest flights from Ohio to Florence
Explore the most affordable flight options available from Ohio to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 4, 2025.

This American Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/48:26 amCAK - FLO
1 stop5h 44mAmerican Airlines
Sat 5/102:36 pmFLO - CAK
1 stop6h 10mAmerican Airlines
Deal found 4/3$395
This American Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1312:26 pmCMH - FLO
2 stops11h 32mAmerican Airlines
Sat 5/172:36 pmFLO - CMH
1 stop4h 48mAmerican Airlines
Deal found 4/3$398
This American Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/246:51 amCVG - FLO
1 stop3h 34mAmerican Airlines
Tue 9/305:23 amFLO - CVG
1 stop5h 09mAmerican Airlines
Deal found 4/3$421
This American Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/96:24 amCLE - FLO
1 stop3h 43mAmerican Airlines
Wed 5/75:00 amFLO - CLE
1 stop4h 44mAmerican Airlines
Deal found 4/3$431
This American Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/168:19 amDTW - FLO
1 stop5h 51mAmerican Airlines
Wed 4/235:00 amFLO - DTW
1 stop5h 38mAmerican Airlines
Deal found 4/3$441
This American Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/28:23 amPIT - FLO
1 stop5h 47mAmerican Airlines
Mon 5/510:38 amFLO - PIT
1 stop5h 32mAmerican Airlines
Deal found 4/4$505
This American Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/186:53 amDAY - FLO
1 stop3h 14mAmerican Airlines
Sun 4/2010:32 amFLO - DAY
1 stop6h 25mAmerican Airlines
Deal found 4/3$519

Cheapflights Fare Finder

Customize your flight search to find flights from Ohio to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 4, 2025.
Use the filters below to find and compare flights from Ohio to Florence that are best for you.

Fly from

Ohio

Fly to

Florence

Route

Depart

Return

Price

AkronFlorence

CAK - FLO

CAKFLO

Akron/Canton

Sun 5/4

8:26 am-2:10 pm

1 stop5h 44m

Florence

Sat 5/10

2:36 pm-8:46 pm

1 stop6h 10m

$395

ColumbusFlorence

CMH - FLO

CMHFLO

Columbus

Tue 5/13

12:26 pm-11:58 pm

2 stops11h 32m

Florence

Sat 5/17

2:36 pm-7:24 pm

1 stop4h 48m

$398

CincinnatiFlorence

CVG - FLO

CVGFLO

Cincinnati Cinci./N. Kentucky

Wed 9/24

6:51 am-10:25 am

1 stop3h 34m

Florence

Tue 9/30

5:23 am-10:32 am

1 stop5h 09m

$421

DetroitFlorence

DTW - FLO

DTWFLO

Detroit Metropolitan Wayne County

Wed 4/16

8:19 am-2:10 pm

1 stop5h 51m

Florence

Wed 4/23

5:00 am-10:38 am

1 stop5h 38m

$441

ClevelandFlorence

CLE - FLO

CLEFLO

Cleveland Hopkins Intl

Sat 5/3

8:15 am-2:10 pm

1 stop5h 55m

Florence

Sun 5/4

2:35 pm-5:58 pm

1 stop3h 23m

$448

PittsburghFlorence

PIT - FLO

PITFLO

Pittsburgh

Fri 5/2

8:23 am-2:10 pm

1 stop5h 47m

Florence

Mon 5/5

10:38 am-4:10 pm

1 stop5h 32m

$505

DaytonFlorence

DAY - FLO

DAYFLO

Dayton

Fri 4/18

6:53 am-10:07 am

1 stop3h 14m

Florence

Sun 4/20

10:32 am-4:57 pm

1 stop6h 25m

$519

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/3

Best time to book a flight from Ohio to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Ohio with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Ohio to Florence

What is the cheapest month to book a flight from Ohio to Florence, South Carolina?

Currently, January is the cheapest month in which you can book a flight from Ohio to Florence, South Carolina (average of $366). Flying from Ohio to Florence, South Carolina in June is currently the most expensive (average of $508). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from OH to FLO?

Find hourly flight availability from Ohio to Florence. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 4, 2025.

When flying from Ohio to Florence, South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Florence by month

Plan your trip to Florence by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Florence, South Carolina ranges from 2.5 - 5.4 inches per month. July is typically the wettest month, when rainfall can reach 5.4 in. November is typically the driest time to visit Florence, South Carolina when rainfall is around 2.5 in.

Temperature in Florence by month

Plan your trip to Florence by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Florence, South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 46.4 F).

Reviews of airlines servicing Florence

Get insights into the airlines that provide service to Florence. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florence. Reviews last updated April 4, 2025.
American Airlines
7.2
Good
10,000 reviews

Entertainment

6.9

Crew

8.0

Food

6.5

Overall

7.2

Boarding

7.5

Comfort

7.2

Reviews

1 / 20
10.0
Excellent

Anonymous,Apr 2025

MYR - CLT

This flight was impacted by a nearly 4, yes 4 hour delay. They replaced a 777 with another one and it had to be cleaned and catered before we could depart. Great crew did it without complaint.
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Entertainment

6.9

Crew

8.0

Food

6.5

Overall

7.2

Boarding

7.5

Comfort

7.2

Reviews

1 / 20
10.0
Excellent

Anonymous,Apr 2025

MYR - CLT

This flight was impacted by a nearly 4, yes 4 hour delay. They replaced a 777 with another one and it had to be cleaned and catered before we could depart. Great crew did it without complaint.

Related info for your journey

Find useful and relevant information for your journey from Ohio to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Florence from Ohio?

    If you book a flight to Florence from Ohio, you will be flying to Florence, which is the city’s only airport. Florence (FLO) is located 2.3 mi from the center of Florence.

  • What are the most popular routes from Ohio to Florence, South Carolina?

    While some choose either Cincinnati Cinci./N. Kentucky - Florence or Akron/Canton - Florence, Cleveland Hopkins Intl - Florence is the most popular route from Ohio to Florence, South Carolina.

  • Can I find deals for flights from Ohio to Florence that include hotel bookings?

    Yes. In addition to deals on Ohio to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Ohio to Florence?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Ohio to Florence.

  • Can I find deals for business class flights from Ohio to Florence?

    Yes. Cheapflights offers flight deals from Ohio to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Ohio to Florence, South Carolina?

    Currently, January is the cheapest month in which you can book a flight from Ohio to Florence, South Carolina (average of $366). Flying from Ohio to Florence, South Carolina in June is currently the most expensive (average of $508). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Ohio?

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Top airline flying from Ohio to Florence

Discover the top airline that operate flights from Ohio to Florence. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 4, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$365Average$530FlexibilityNo cancel feeOn-time71%

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