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$296+ Cheap flights from Ohio to Florence, SC (FLO)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/5. Fares are subject to change and may not be available on all flights or dates of travel.
CLE — FLO
Mar 8 — Mar 151
Sat 3/8
Sat 3/15
1 adult, Economy
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Cheap flight deals from Ohio to Florence

Keep the following information in mind while searching for Ohio to Florence flight deals. Data was last updated March 3, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$296
(American Airlines)
Provider with most accurate pricing for Cleveland Hopkins Intl-Florence flight deals.
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Provider most trusted by Cheapflights users for Cleveland Hopkins Intl-Florence flights.
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From Ohio to Florence
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Find flight deals from Ohio to Florence

Cheapest flights from Ohio to Florence
Explore the most affordable flight options available from Ohio to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 3, 2025.

This American Airlines deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/55:21 pmDTW - FLO
1 stop6h 33mAmerican Airlines
Wed 4/92:35 pmFLO - DTW
2 stops10h 02mAmerican Airlines
Deal found 3/3$296
This American Airlines deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2412:35 pmPIT - FLO
2 stops11h 19mAmerican Airlines
Mon 4/282:35 pmFLO - PIT
2 stops8h 56mAmerican Airlines
Deal found 3/2$368
This American Airlines deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/49:52 amCLE - FLO
1 stop4h 16mAmerican Airlines
Tue 3/1111:14 amFLO - CLE
1 stop5h 48mAmerican Airlines
Deal found 3/2$436
This American Airlines deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/25:22 pmDAY - FLO
1 stop6h 34mAmerican Airlines
Thu 8/74:12 pmFLO - DAY
1 stop3h 26mAmerican Airlines
Deal found 3/2$470
This American Airlines deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/2512:16 pmCMH - FLO
2 stops11h 35mAmerican Airlines
Sat 3/295:00 amFLO - CMH
2 stops9h 04mAmerican Airlines
Deal found 3/2$518
This American Airlines deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/196:16 amCVG - FLO
1 stop4h 23mAmerican Airlines
Sun 6/2211:06 amFLO - CVG
1 stop6h 17mAmerican Airlines
Deal found 3/2$520
This American Airlines deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/226:00 amCAK - FLO
2 stops8h 05mAmerican Airlines
Mon 3/245:00 amFLO - CAK
1 stop5h 44mAmerican Airlines
Deal found 3/2$587

Find flights from Ohio to Florence within your budget

Customize your flight search to find flights from Ohio to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 3, 2025.

Fly from

Ohio

Fly to

Florence

Route

Depart

Return

Price

DetroitFlorence

DTW - FLO

DTWFLO

Detroit Metropolitan Wayne County

Sat 4/5

5:21 pm-11:54 pm

1 stop6h 33m

Florence

Wed 4/9

2:35 pm-12:37 am

2 stops10h 02m

$296

PittsburghFlorence

PIT - FLO

PITFLO

Pittsburgh

Thu 4/24

12:35 pm-11:54 pm

2 stops11h 19m

Florence

Mon 4/28

2:35 pm-11:31 pm

2 stops8h 56m

$368

DaytonFlorence

DAY - FLO

DAYFLO

Dayton

Sat 8/2

5:22 pm-11:56 pm

1 stop6h 34m

Florence

Thu 8/7

4:12 pm-7:38 pm

1 stop3h 26m

$470

ClevelandFlorence

CLE - FLO

CLEFLO

Cleveland Hopkins Intl

Tue 6/10

7:42 pm-11:55 pm

1 stop4h 13m

Florence

Tue 6/17

2:33 pm-6:46 pm

1 stop4h 13m

$486

ColumbusFlorence

CMH - FLO

CMHFLO

Columbus

Tue 3/25

12:16 pm-11:51 pm

2 stops11h 35m

Florence

Sat 3/29

5:00 am-2:04 pm

2 stops9h 04m

$518

CincinnatiFlorence

CVG - FLO

CVGFLO

Cincinnati Cinci./N. Kentucky

Thu 6/19

6:16 am-10:39 am

1 stop4h 23m

Florence

Sun 6/22

11:06 am-5:23 pm

1 stop6h 17m

$520

AkronFlorence

CAK - FLO

CAKFLO

Akron/Canton

Sat 3/22

6:00 am-2:05 pm

2 stops8h 05m

Florence

Mon 3/24

5:00 am-10:44 am

1 stop5h 44m

$587

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/3

Best time to book a flight from Ohio to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Ohio with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Ohio to Florence

Get recent, data-driven insights about flights from Ohio to Florence including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Ohio to Florence, South Carolina?

Currently, January is the cheapest month in which you can book a flight from Ohio to Florence, South Carolina (average of $366). Flying from Ohio to Florence, South Carolina in June is currently the most expensive (average of $518). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from OH to FLO?

Find hourly flight availability from Ohio to Florence. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 3, 2025.

When flying from Ohio to Florence, South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Florence by month

Plan your trip to Florence by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Florence, South Carolina ranges from 2.5 - 5.4 inches per month. July is typically the wettest month, when rainfall can reach 5.4 in. November is typically the driest time to visit Florence, South Carolina when rainfall is around 2.5 in.

Temperature in Florence by month

Plan your trip to Florence by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Florence, South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 46.4 F).

Reviews of airlines servicing Florence

Get insights into the airlines that provide service to Florence. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florence. Reviews last updated March 3, 2025.
American Airlines
7.2
Good
10,000 reviews

Entertainment

7.0

Crew

8.0

Boarding

7.5

Comfort

7.3

Food

6.5

Overall

7.2

Reviews

1 / 20

10.0
Excellent

Anonymous,Jan 2025

PIT - DFW

Due to gate changes,we nearly missed our flight. The gate agent reassigned our seats and would NOT give us our assigned seats,but she did honor that same request to the man who arrived after us. Her rudeness and difficulty was not appropriate.

American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Entertainment

7.0

Crew

8.0

Boarding

7.5

Comfort

7.3

Food

6.5

Overall

7.2

Reviews

1 / 20

10.0
Excellent

Anonymous,Jan 2025

PIT - DFW

Due to gate changes,we nearly missed our flight. The gate agent reassigned our seats and would NOT give us our assigned seats,but she did honor that same request to the man who arrived after us. Her rudeness and difficulty was not appropriate.

Related info for your journey

Find useful and relevant information for your journey from Ohio to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Florence from Ohio?

    If you book a flight to Florence from Ohio, you will be flying to Florence, which is the city’s only airport. Florence (FLO) is located 2.3 mi from the center of Florence.

  • What are the most popular routes from Ohio to Florence, South Carolina?

    While some choose either Cleveland Hopkins Intl - Florence or Columbus - Florence, Akron/Canton - Florence is the most popular route from Ohio to Florence, South Carolina.

  • Can I find deals for flights from Ohio to Florence that include hotel bookings?

    Yes. In addition to deals on Ohio to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Ohio to Florence?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Ohio to Florence.

  • Can I find deals for business class flights from Ohio to Florence?

    Yes. Cheapflights offers flight deals from Ohio to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Ohio to Florence, South Carolina?

    Currently, January is the cheapest month in which you can book a flight from Ohio to Florence, South Carolina (average of $366). Flying from Ohio to Florence, South Carolina in June is currently the most expensive (average of $518). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Ohio?

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Top airline flying from Ohio to Florence

Discover the top airline that operate flights from Ohio to Florence. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 3, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$365Average$530FlexibilityNo cancel feeOn-time71%
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