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$446+ Cheap flights from Colorado to Florence, SC (FLO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/31. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — FLO
Apr 5 — Apr 121
Sat 4/5
Sat 4/12
1 adult, Economy
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Cheap flight deals from Colorado to Florence

Keep the following information in mind while searching for Colorado to Florence flight deals. Data was last updated March 31, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$955
(American Airlines)

One-way from

$446
(American Airlines)

Popular in

August

Cheapest in

December

Average price

$533
Provider with most accurate pricing for Denver Intl-Florence flight deals.
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Provider most trusted by Cheapflights users for Denver Intl-Florence flights.
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From Colorado to Florence
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One-way flight from Colorado to Florence
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Highest demand for flights based on searches. 6% potential increase in price ($37 potential increase over avg. RT price).
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Cheapest flight prices on average. 6% potential price decrease ($35 potential savings vs. average RT price).
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Average for round-trip flights in March 2025
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Find flight deals from Colorado to Florence

Cheapest flights from Colorado to Florence
Explore the most affordable flight options available from Colorado to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 31, 2025.

This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/147:20 amDEN - FLO
2 stops14h 34mAmerican Airlines
Fri 4/182:35 pmFLO - DEN
1 stop8h 41mAmerican Airlines
Deal found 3/30$955

Cheapflights Fare Finder

Customize your flight search to find flights from Colorado to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 31, 2025.
Use the filters below to find and compare flights from Colorado to Florence that are best for you.

Fly from

Colorado

Fly to

Florence

Route

Depart

Return

Price

DenverFlorence

DEN - FLO

DENFLO

Denver Intl

Mon 4/14

7:20 am-11:54 pm

2 stops14h 34m

Florence

Fri 4/18

2:35 pm-9:16 pm

1 stop8h 41m

$955

DenverFlorence

DEN - FLO

DENFLO

Denver Intl

Sat 5/31

9:06 am-11:58 pm

2 stops12h 52m

$446

Colorado SpringsFlorence

COS - FLO

COSFLO

Colorado Springs

Thu 6/12

10:50 am-11:55 pm

2 stops11h 05m

$519

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/30

Best time to book a flight from Colorado to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Colorado with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Colorado to Florence

What is the cheapest month to book a flight from Colorado to Florence, South Carolina?

Currently, January is the cheapest month in which you can book a flight from Colorado to Florence, South Carolina (average of $366). Flying from Colorado to Florence, South Carolina in June is currently the most expensive (average of $508). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CO to FLO?

Find hourly flight availability from Colorado to Florence. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 31, 2025.

When flying from Colorado to Florence, South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Florence by month

Plan your trip to Florence by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Florence, South Carolina ranges from 2.5 - 5.4 inches per month. July is typically the wettest month, when rainfall can reach 5.4 in. November is typically the driest time to visit Florence, South Carolina when rainfall is around 2.5 in.

Temperature in Florence by month

Plan your trip to Florence by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Florence, South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 46.4 F).

Reviews of airlines servicing Florence

Get insights into the airlines that provide service to Florence. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florence. Reviews last updated March 31, 2025.
American Airlines
7.2
Good
10,000 reviews

Boarding

7.5

Crew

8.0

Entertainment

6.9

Overall

7.2

Comfort

7.2

Food

6.5

Reviews

1 / 20
6.0
Good

sheila,Mar 2025

DFW - MSP

We were delayed for 3 hours with no real reason or offer for compensation
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Boarding

7.5

Crew

8.0

Entertainment

6.9

Overall

7.2

Comfort

7.2

Food

6.5

Reviews

1 / 20
6.0
Good

sheila,Mar 2025

DFW - MSP

We were delayed for 3 hours with no real reason or offer for compensation

Related info for your journey

Find useful and relevant information for your journey from Colorado to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Florence from Colorado?

    Most people fly into Florence (FLO) if they book a flight to Florence from Colorado. Florence is conveniently located just 2.3 mi from Florence’s city center.

  • What are the most popular routes from Colorado to Florence, South Carolina?

    The most popular route from Colorado to Florence, South Carolina is Montrose County - Florence. You may also consider Grand Junction Regnl - Florence or Colorado Springs - Florence.

  • Can I find deals for flights from Colorado to Florence that include hotel bookings?

    Yes. In addition to deals on Colorado to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Colorado to Florence?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Colorado to Florence.

  • Can I find deals for business class flights from Colorado to Florence?

    Yes. Cheapflights offers flight deals from Colorado to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Colorado to Florence, South Carolina?

    Currently, January is the cheapest month in which you can book a flight from Colorado to Florence, South Carolina (average of $366). Flying from Colorado to Florence, South Carolina in June is currently the most expensive (average of $508). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Colorado?

Book flights to Colorado if you plan to visit one of these locations
Hartsville
Darlington
Sumter
Bennettsville

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Top airline flying from Colorado to Florence

Discover the top airline that operate flights from Colorado to Florence. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$375Average$506FlexibilityNo cancel feeOn-time71%
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