HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Florence

$349+ Cheap flights from Boston to Florence, SC (BOS - FLO)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/1. Fares are subject to change and may not be available on all flights or dates of travel.
BOS — FLO
Jan 4 — Jan 111
Sun 1/4
Sun 1/11
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Boston to Florence with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Boston to Florence

Cheapest flights from Boston to Florence
Explore the most affordable flight options available from Boston to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 5, 2025.

This American Airlines deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/286:30 pmBOS - FLO
1 stop5h 45mAmerican Airlines
Wed 1/75:36 pmFLO - BOS
1 stop4h 46mAmerican Airlines
Deal found 12/3$449
This American Airlines deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/291:35 pmBOS - FLO
1 stop4h 30mAmerican Airlines
Wed 1/75:36 pmFLO - BOS
1 stop6h 15mAmerican Airlines
Deal found 12/3$450
This American Airlines deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/295:59 amBOS - FLO
2 stops6h 27mAmerican Airlines
Tue 1/136:15 amFLO - BOS
2 stops9h 00mAmerican Airlines
Deal found 12/3$459
This American Airlines deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/286:30 pmBOS - FLO
1 stop5h 45mAmerican Airlines
Mon 1/126:15 amFLO - BOS
1 stop6h 43mAmerican Airlines
Deal found 12/3$469
This American Airlines deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/295:00 pmBOS - FLO
2 stops7h 15mAmerican Airlines
Thu 1/86:15 amFLO - BOS
2 stops7h 58mAmerican Airlines
Deal found 12/3$479
This American Airlines deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/235:59 amBOS - FLO
2 stops6h 27mAmerican Airlines
Thu 12/258:00 amFLO - BOS
2 stops10h 06mAmerican Airlines
Deal found 12/3$609

Find flight deals from Boston to Florence

Discover tips and strategies to find the most affordable flight options for your journey from Boston (BOS) to Florence (FLO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 5, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$349
(American Airlines)

Popular in

April

Cheapest in

November

Average price

$509
Provider with most accurate pricing for Boston Logan Intl-Florence flight deals.
Search Deals
Provider most trusted by Cheapflights users for Boston Logan Intl-Florence flights.
Search Deals
From Boston Logan Intl to Florence
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($49 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($13 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Boston to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 5, 2025.
Use the filters below to find and compare flights from Boston to Florence that are best for you.

Fly from

Boston

Fly to

Florence

Route

Depart

Return

Price

BostonFlorence

BOS - FLO

BOSFLO

Boston Logan Intl

Thu 1/1

1:35 pm-6:05 pm

1 stop4h 30m

Florence

Thu 1/8

5:36 pm-11:51 pm

1 stop6h 15m

$349

BostonFlorence

BOS - FLO

BOSFLO

Boston Logan Intl

Sun 12/28

6:30 pm-12:15 am

1 stop5h 45m

Florence

Wed 1/7

5:36 pm-10:22 pm

1 stop4h 46m

$449

BostonFlorence

BOS - FLO

BOSFLO

Boston Logan Intl

Mon 12/29

10:55 am-6:05 pm

1 stop7h 10m

Florence

Tue 1/13

6:15 am-10:29 am

1 stop4h 14m

$449

BostonFlorence

BOS - FLO

BOSFLO

Boston Logan Intl

Mon 12/29

1:35 pm-6:05 pm

1 stop4h 30m

Florence

Wed 1/7

5:36 pm-11:51 pm

1 stop6h 15m

$450

BostonFlorence

BOS - FLO

BOSFLO

Boston Logan Intl

Mon 12/29

10:55 am-6:05 pm

1 stop7h 10m

Florence

Mon 1/12

5:36 pm-11:51 pm

1 stop6h 15m

$469

BostonFlorence

BOS - FLO

BOSFLO

Boston Logan Intl

Sun 12/28

6:30 pm-12:15 am

1 stop5h 45m

Florence

Mon 1/12

6:15 am-12:58 pm

1 stop6h 43m

$469

BostonFlorence

BOS - FLO

BOSFLO

Boston Logan Intl

Sun 12/28

6:30 pm-12:15 am

1 stop5h 45m

Florence

Thu 1/8

5:36 pm-10:22 pm

1 stop4h 46m

$469

BostonFlorence

BOS - FLO

BOSFLO

Boston Logan Intl

Tue 12/23

6:30 pm-12:15 am

1 stop5h 45m

Florence

Thu 12/25

12:51 pm-6:25 pm

1 stop5h 34m

$469

BostonFlorence

BOS - FLO

BOSFLO

Boston Logan Intl

Mon 12/29

6:30 pm-12:15 am

1 stop5h 45m

Florence

Thu 1/8

6:15 am-2:13 pm

2 stops7h 58m

$474

BostonFlorence

BOS - FLO

BOSFLO

Boston Logan Intl

Sat 12/27

5:30 pm-12:15 am

1 stop6h 45m

$373

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/4

Showing 1-10 of 13 results
1
2

Compare providers for flights from Boston to Florence

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Boston to Florence in December.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Boston-Florence, South Carolina flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Boston-Florence, South Carolina flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Boston-Florence, South Carolina flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Boston-Florence, South Carolina flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Boston-Florence, South Carolina flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Boston to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Boston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Boston to Florence

What is the cheapest month to book a flight from Boston to Florence, South Carolina?

Currently, August is the cheapest month in which you can book a flight from Boston to Florence, South Carolina (average of $58). Flying from Boston to Florence, South Carolina in June is currently the most expensive (average of $77). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from BOS to FLO?

Find hourly flight availability from Boston to Florence. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 5, 2025.

When flying from Boston to Florence, South Carolina, the time of day you fly usually plays a role in the price. Save by searching for a flight in the afternoon, which can drop the price by up to 7% versus a flight in the morning.

Reviews of airlines servicing Florence

Get insights into the airlines that provide service to Florence. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florence. Reviews last updated December 5, 2025.
See what other customers who have flown with American Airlines from Boston to Florence have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,047 reviews

Overall

7.2

Food

6.5

Entertainment

6.9

Comfort

7.2

Crew

8.0

Boarding

7.5

Reviews

1 / 20
8.0
Excellent

Monica,Nov 2025

JAC - DFW

At least there was an option of entertainment on this flight.
American Airlines
7.2
Good
11,047 reviews
American Airlines
7.2
Good
11,047 reviews

Overall

7.2

Food

6.5

Entertainment

6.9

Comfort

7.2

Crew

8.0

Boarding

7.5

Reviews

1 / 20
8.0
Excellent

Monica,Nov 2025

JAC - DFW

At least there was an option of entertainment on this flight.

Related info for your journey

Find useful and relevant information for your journey from Boston to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Boston to Florence, South Carolina?

    Departing from Boston to Florence, South Carolina will take you 4h 30m. There are 735 mi between Boston and Florence, South Carolina.

  • What is the cheapest airline to fly from Boston to Florence, South Carolina round-trip?

    According to our current data, American Airlines ($368), offers the cheapest pricing from Boston to Florence, South Carolina. You may be able to fly from Boston to Florence, South Carolina for 23% less than the average price by searching for this airline.

  • Can I find deals for flights from Boston to Florence that include hotel bookings?

    Yes. In addition to deals on Boston to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Boston to Florence?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Boston to Florence.

  • Can I find deals for business class flights from Boston to Florence?

    Yes. Cheapflights offers flight deals from Boston to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Boston to Florence, South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Boston to Florence, South Carolina (average of $58). Flying from Boston to Florence, South Carolina in June is currently the most expensive (average of $77). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Hartsville
Darlington

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Boston to Florence

See prices for flight routes from nearby airports that may be better suited for you.
Boston to Charlotte flights
Boston to Charleston flights
Boston to Savannah flights
Boston to Myrtle Beach flights
Hartford to Charlotte flights
Hartford to Myrtle Beach flights
Hartford to Charleston flights
Albany to Myrtle Beach flights
Albany to Charlotte flights
Albany to Savannah flights
Hartford to Savannah flights
Boston to Hilton Head Island flights
Boston to Greenville flights
Albany to Charleston flights
Boston to Columbia flights
Boston to Augusta flights
Hartford to Greenville flights
Albany to Greenville flights
Hartford to Columbia flights
Hartford to Augusta flights
Hartford to Hilton Head Island flights
Worcester to Charleston flights
Hartford to Florence flights
Albany to Columbia flights
Hyannis to Charleston flights
West Tisbury to Savannah flights
Albany to Augusta flights
New Bedford to Charleston flights
Provincetown to Charleston flights
Provincetown to Charlotte flights
Nantucket to Charleston flights
West Tisbury to Myrtle Beach flights
West Tisbury to Charleston flights
Hyannis to Charlotte flights
Albany to Florence flights
Nantucket to Charlotte flights

Top airline flying from Boston to Florence

Discover the top airline that operate flights from Boston to Florence. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 5, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$368Average$466FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.
Site
Cookie settings©2025 Cheapflights