HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Durham

$55+ Cheap flights from St. Louis (STL) to Durham, NC

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/23. Fares are subject to change and may not be available on all flights or dates of travel.
STL — RDU
Feb 25 — Mar 41
Tue 2/25
Tue 3/4
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from St. Louis to Durham with Cheapflights

1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”
2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.
3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

The best prices from Lambert-St Louis to Durham are usually found in April or June, booked 61 days in advance, depart on a Saturday or Sunday and return on a Saturday

Cheap flight deals from St. Louis to Durham

Keep the following information in mind while searching for St. Louis to Durham flight deals. Data was last updated February 20, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$109
(Frontier)

One-way from

$55
(Frontier)

Popular in

February

Cheapest in

April

Average price

$384
Provider with most accurate pricing for Lambert-St Louis-Raleigh-Durham flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Raleigh-Durham flights.
Search Deals
From Lambert-St Louis to Durham
Search Deals
One-way flight from Lambert-St Louis to Durham
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($37 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($5 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2025
Search Deals

Find flight deals from St. Louis to Durham

Cheapest flights from St. Louis to Durham
Explore the most affordable flight options available from St. Louis to Durham. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 20, 2025.

This Frontier deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/1010:36 amSTL - RDU
1 stop9h 40mFrontier
Sat 3/1510:16 pmRDU - STL
1 stop10h 42mFrontier
Deal found 2/18$109
This FlightHub deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/246:11 pmSTL - RDU
1 stop25h 42mMultiple Airlines
Sat 4/266:05 amRDU - STL
1 stop18h 59mMultiple Airlines
Deal found 2/19$160
This American Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/195:55 amSTL - RDU
1 stop6h 08mAmerican Airlines
Wed 3/266:00 amRDU - STL
1 stop6h 24mAmerican Airlines
Deal found 2/18$188
This Southwest deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/217:45 amSTL - RDU
Nonstop1h 50mSouthwest
Mon 3/248:35 pmRDU - STL
Nonstop2h 15mSouthwest
Deal found 2/19$277
This United Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/193:30 pmSTL - RDU
1 stop4h 38mUnited Airlines
Wed 3/269:30 amRDU - STL
1 stop7h 01mUnited Airlines
Deal found 2/19$343
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1910:30 amSTL - RDU
1 stop5h 04mDelta
Sun 4/205:20 amRDU - STL
1 stop5h 25mDelta
Deal found 2/19$351
This Alaska Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/256:15 amSTL - RDU
2 stops22h 45mAlaska Airlines
Sun 4/277:20 amRDU - STL
2 stops26h 41mAlaska Airlines
Deal found 2/18$873

Find flights from St. Louis to Durham within your budget

Customize your flight search to find flights from St. Louis to Durham that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.

Fly from

St. Louis

Fly to

Durham

Route

Depart

Return

Price

St. LouisRaleigh

STL - RDU

STLRDU

Lambert-St Louis

Mon 3/10

10:36 am-9:16 pm

1 stop9h 40m

Raleigh-Durham

Sat 3/15

10:16 pm-7:58 am

1 stop10h 42m

$109

St. LouisRaleigh

STL - RDU

STLRDU

Lambert-St Louis

Thu 4/24

6:11 pm-8:53 pm

1 stop25h 42m

Raleigh-Durham

Sat 4/26

6:05 am-12:04 am

1 stop18h 59m

$160

St. LouisRaleigh

STL - RDU

STLRDU

Lambert-St Louis

Wed 3/19

5:55 am-1:03 pm

1 stop6h 08m

Raleigh-Durham

Wed 3/26

6:00 am-11:24 am

1 stop6h 24m

$188

St. LouisRaleigh

STL - RDU

STLRDU

Lambert-St Louis

Fri 3/21

7:45 am-10:35 am

Nonstop1h 50m

Raleigh-Durham

Mon 3/24

8:35 pm-9:50 pm

Nonstop2h 15m

$277

St. LouisRaleigh

STL - RDU

STLRDU

Lambert-St Louis

Wed 3/19

3:30 pm-9:08 pm

1 stop4h 38m

Raleigh-Durham

Wed 3/26

9:30 am-3:31 pm

1 stop7h 01m

$343

St. LouisRaleigh

STL - RDU

STLRDU

Lambert-St Louis

Sat 4/19

10:30 am-4:34 pm

1 stop5h 04m

Raleigh-Durham

Sun 4/20

5:20 am-9:45 am

1 stop5h 25m

$351

St. LouisRaleigh

STL - RDU

STLRDU

Lambert-St Louis

Fri 4/25

6:15 am-6:00 am

2 stops22h 45m

Raleigh-Durham

Sun 4/27

7:20 am-9:01 am

2 stops26h 41m

$873

St. LouisRaleigh

STL - RDU

STLRDU

Lambert-St Louis

Wed 4/23

5:41 pm-11:59 pm

1 stop5h 18m

$55

St. LouisRaleigh

STL - RDU

STLRDU

Lambert-St Louis

Tue 5/20

7:37 pm-7:48 pm

1 stop23h 11m

$74

St. LouisRaleigh

STL - RDU

STLRDU

Lambert-St Louis

Tue 3/4

9:50 am-8:29 pm

3 stops33h 39m

$127

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/20

Showing 1-10 of 15 results
1
2

Best time to book a flight from St. Louis to Durham

Have a flexible travel schedule? Discover the best time to fly to Durham from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from St. Louis to Durham

Get recent, data-driven insights about flights from St. Louis to Durham including ideal travel times, pricing trends, and more.

How far ahead should I book a flight from St. Louis to Durham?

Use this chart to determine the optimal time to book a round-trip flight from St. Louis to Durham. Price data was last updated on February 14, 2025.

The best time to book flights from St. Louis to Durham is 61 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from St. Louis to Durham?

Currently, August is the cheapest month in which you can book a flight from St. Louis to Durham (average of $206). Flying from St. Louis to Durham in March is currently the most expensive (average of $316). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from STL to DU8?

Find hourly flight availability from St. Louis to Durham. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 20, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from St. Louis to Durham as you normally would.

What is the cheapest day to fly from St. Louis to Durham?

Use this chart to determine the cheapest time to fly round-trip from St. Louis to Durham. Price data was last updated on November 3, 2024.

Travelers seeking maximum savings on their St. Louis to Durham flight should consider departing on Wednesday evenings when fares are most often at their lowest. Friday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Rainfall in Durham by month

Plan your trip to Durham by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Durham ranges from 2.9 - 4.7 inches per month. July is typically the wettest month, when rainfall can reach 4.7 in. April is typically the driest time to visit Durham when rainfall is around 2.9 in.

Temperature in Durham by month

Plan your trip to Durham by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Durham, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 41.0 F).

Reviews of airlines servicing Durham

Get insights into the airlines that provide service to Durham. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Durham. Reviews last updated February 20, 2025.
Get a feel of what it's like to fly with Southwest, Alaska Airlines and Delta from St. Louis to Durham by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
4,411 reviews

Food

7.1

Boarding

8.2

Comfort

8.1

Overall

8.1

Crew

8.7

Entertainment

7.6

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Southwest
8.1
Very good
4,411 reviews
Southwest
8.1
Very good
4,411 reviews

Food

7.1

Boarding

8.2

Comfort

8.1

Overall

8.1

Crew

8.7

Entertainment

7.6

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Alaska Airlines
8.0
Very good
9,697 reviews
Southwest
8.1
Very good
4,411 reviews

Food

7.1

Boarding

8.2

Comfort

8.1

Overall

8.1

Crew

8.7

Entertainment

7.6

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Delta
8.0
Very good
8,219 reviews
Southwest
8.1
Very good
4,411 reviews

Food

7.1

Boarding

8.2

Comfort

8.1

Overall

8.1

Crew

8.7

Entertainment

7.6

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

United Airlines
7.4
Good
8,765 reviews
Southwest
8.1
Very good
4,411 reviews

Food

7.1

Boarding

8.2

Comfort

8.1

Overall

8.1

Crew

8.7

Entertainment

7.6

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

American Airlines
7.2
Good
10,000 reviews
Southwest
8.1
Very good
4,411 reviews

Food

7.1

Boarding

8.2

Comfort

8.1

Overall

8.1

Crew

8.7

Entertainment

7.6

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Durham. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from St. Louis to Durham?

    Lambert-St Louis (STL), located 12.7 mi from the city center, is the airport you fly out of when you book flights from St. Louis to Durham. 5 airlines have flights from Lambert-St Louis to Durham on a regular basis. Booking flights from Lambert-St Louis to Durham should not be difficult; the airport handles an average of 0 outbound flights to Durham per day.

  • How popular is this St. Louis to Durham flight route?

    Within the past month, 1 users have taken a look at flights from Lambert-St Louis to Durham.

  • What are the cheapest airlines to fly from St. Louis to Durham one-way?

    $55 is the cheapest one-way deal found within the past few days, from Frontier. You may also be able to find cheap deals on Spirit Airlines and Southwest, with prices starting from $74 and $129, respectively.

  • What are the cheapest flights from St. Louis to Durham?

    Looking for the cheapest flight from St. Louis to Durham? While on average our users pay $289, our data indicates the cheapest price to be $197. The most popular route (Lambert-St Louis - Raleigh-Durham), is priced around $160.

  • Can I find deals for flights from St. Louis to Durham that include hotel bookings?

    Yes. In addition to deals on St. Louis to Durham flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Durham?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Durham.

  • Can I find deals for business class flights from St. Louis to Durham?

    Yes. Cheapflights offers flight deals from St. Louis to Durham by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from St. Louis to Durham?

    Currently, August is the cheapest month in which you can book a flight from St. Louis to Durham (average of $206). Flying from St. Louis to Durham in March is currently the most expensive (average of $316). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for St. Louis to Durham

See prices for flight routes from nearby airports that may be better suited for you.
St. Louis to Raleigh flights
Kansas City to Charlotte flights
St. Louis to Charlotte flights
Kansas City to Myrtle Beach flights
Kansas City to Raleigh flights
Kansas City to Wilmington flights
St. Louis to Myrtle Beach flights
Kansas City to Knoxville flights
Kansas City to Norfolk flights
St. Louis to Norfolk flights
St. Louis to Wilmington flights
St. Louis to Greensboro flights
St. Louis to Knoxville flights
Springfield to Charlotte flights
Springfield to Raleigh flights
Kansas City to Greensboro flights
Kansas City to Asheville flights
St. Louis to Asheville flights
St. Louis to Fayetteville flights
Springfield to Myrtle Beach flights
Kansas City to Fayetteville flights
Columbia to Knoxville flights
St. Louis to Jacksonville flights
Kansas City to New Bern flights
Springfield to Norfolk flights
Columbia to Myrtle Beach flights
Columbia to Asheville flights
Joplin to Raleigh flights
Springfield to Asheville flights
Springfield to Knoxville flights
Kansas City to Jacksonville flights
Springfield to Greensboro flights
Springfield to Wilmington flights
St. Louis to Blountville flights
Joplin to Charlotte flights
St. Louis to New Bern flights
Kansas City to Greenville flights
Cape Girardeau to Charlotte flights
St. Louis to Greenville flights
Columbia to Charlotte flights
Columbia to Norfolk flights
Kansas City to Blountville flights
Springfield to Fayetteville flights

Top 5 airlines flying from St. Louis to Durham

Discover the top 5 airlines that operate flights from St. Louis to Durham. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$108Average$160FlexibilityNo cancel feeOn-time62%
SouthwestCheapest$212Average$352FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$218Average$382FlexibilityNo cancel feeOn-time71%
DeltaCheapest$228Average$364FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$325Average$432FlexibilityNo cancel feeOn-time69%
100% Free
Cheapflights is completely free to use, so you can start saving the moment you arrive.
Book with Flexibility
Our users can plan ahead with confidence and find flights with no change fees
Travel Smart
Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.