HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Durham

$149+ Cheap flights from Mississippi to Durham, NC

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/3. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — RDU
Dec 23 — Dec 301
Mon 12/23
Mon 12/30
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Mississippi to Durham with Cheapflights

1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”
2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.
3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Mississippi to Durham

Discover tips and strategies to find the most affordable flight options for your journey from Mississippi (USMS) to Durham (DU8). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 18, 2024.

Round-trip from

$207
(eDestinos)

One-way from

$149
(Delta)
From Mississippi to Durham
Search Deals
One-way flight from Mississippi to Durham
Search Deals

Find flight deals from Mississippi to Durham

Cheapest flights from Mississippi to Durham
Explore the most affordable flight options available from Mississippi to Durham. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2024.

This Delta deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/226:00 amMOB - RDU
1 stop3h 27mDelta
Sat 1/46:56 amRDU - MOB
1 stop5h 33mDelta
Deal found 12/17$294
This American Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/215:10 amMOB - RDU
1 stop4h 04mAmerican Airlines
Sat 1/44:20 pmRDU - MOB
1 stop6h 30mAmerican Airlines
Deal found 12/17$319
This Delta deal was found by Cheapflights users on 12/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/237:09 pmBTR - RDU
1 stop3h 43mDelta
Fri 12/2712:36 pmRDU - BTR
1 stop6h 48mDelta
Deal found 12/18$403
This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/235:18 amJAN - RDU
1 stop4h 06mAmerican Airlines
Wed 1/12:54 pmRDU - JAN
1 stop6h 05mAmerican Airlines
Deal found 12/16$406
This American Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/2012:55 pmGPT - RDU
1 stop3h 25mAmerican Airlines
Sun 12/224:20 pmRDU - GPT
1 stop6h 52mAmerican Airlines
Deal found 12/17$418
This Delta deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2311:45 amJAN - RDU
1 stop6h 18mDelta
Wed 1/15:59 pmRDU - JAN
1 stop6h 01mDelta
Deal found 12/17$441
This Southwest deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/236:00 pmJAN - RDU
1 stop5h 20mSouthwest
Wed 1/16:20 amRDU - JAN
2 stops9h 50mSouthwest
Deal found 12/17$446
This Mytrip deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/218:00 pmMEM - RDU
2 stops14h 15mMultiple Airlines
Sat 1/47:30 amRDU - MEM
2 stops12h 35mMultiple Airlines
Deal found 12/16$491
This American Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/234:39 pmBTR - RDU
1 stop14h 33mAmerican Airlines
Mon 12/307:00 amRDU - BTR
1 stop6h 29mAmerican Airlines
Deal found 12/17$554
This Delta deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/236:00 amGPT - RDU
1 stop3h 26mDelta
Fri 12/278:10 pmRDU - GPT
1 stop4h 15mDelta
Deal found 12/17$568
This Delta deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/217:15 amMEM - RDU
1 stop5h 24mDelta
Sat 1/46:15 pmRDU - MEM
1 stop6h 06mDelta
Deal found 12/16$586
This United Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/317:15 amBTR - RDU
1 stop7h 18mUnited Airlines
Tue 7/86:30 amRDU - BTR
1 stop6h 01mUnited Airlines
Deal found 12/17$605

Find flights from Mississippi to Durham within your budget

Customize your flight search to find flights from Mississippi to Durham that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2024.

Fly from

Any airport

Fly to

Any airport

Route

Depart

Return

Price

MemphisRaleigh

MEM - RDU

MEMRDU

Memphis

Wed 1/22

9:45 am-7:58 am

1 stop21h 13m

Raleigh-Durham

Thu 1/23

3:07 pm-5:44 pm

2 stops27h 37m

$207

MemphisRaleigh

MEM - RDU

MEMRDU

Memphis

Sun 1/5

12:40 pm-11:19 am

1 stop21h 39m

Raleigh-Durham

Thu 1/9

5:20 pm-5:42 pm

1 stop25h 22m

$233

MobileRaleigh

MOB - RDU

MOBRDU

Mobile

Tue 1/28

7:04 pm-11:58 pm

1 stop3h 54m

Raleigh-Durham

Sat 2/1

11:07 am-2:55 pm

1 stop4h 48m

$244

GulfportRaleigh

GPT - RDU

GPTRDU

Gulfport Biloxi Regional

Thu 1/16

7:01 am-3:42 pm

1 stop7h 41m

Raleigh-Durham

Wed 1/22

1:00 pm-7:46 pm

1 stop7h 46m

$248

Baton RougeRaleigh

BTR - RDU

BTRRDU

Baton Rouge Ryan

Thu 1/23

5:44 pm-11:58 pm

1 stop5h 14m

Raleigh-Durham

Sat 1/25

2:41 pm-8:23 pm

1 stop6h 42m

$248

Baton RougeRaleigh

BTR - RDU

BTRRDU

Baton Rouge Ryan

Wed 1/8

5:30 am-2:00 pm

2 stops7h 30m

Raleigh-Durham

Tue 1/14

12:52 pm-4:02 pm

1 stop4h 10m

$253

MobileRaleigh

MOB - RDU

MOBRDU

Mobile

Tue 1/28

12:55 pm-11:44 pm

2 stops9h 49m

Raleigh-Durham

Sat 2/1

4:48 pm-10:00 pm

1 stop6h 12m

$253

JacksonRaleigh

JAN - RDU

JANRDU

Jackson-Evers Intl

Wed 1/15

5:40 am-11:36 am

1 stop4h 56m

Raleigh-Durham

Tue 1/21

11:07 am-4:20 pm

1 stop6h 13m

$286

MemphisRaleigh

MEM - RDU

MEMRDU

Memphis

Wed 1/15

7:12 am-2:00 pm

1 stop5h 48m

Raleigh-Durham

Sat 1/18

11:18 am-2:26 pm

1 stop4h 08m

$291

JacksonRaleigh

JAN - RDU

JANRDU

Jackson-Evers Intl

Sat 1/18

7:01 am-3:42 pm

1 stop7h 41m

Raleigh-Durham

Wed 1/22

6:00 am-1:27 pm

1 stop8h 27m

$291

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/18

Showing 1-10 of 29 results
1
2
3

Best time to book a flight from Mississippi to Durham

Have a flexible travel schedule? Discover the best time to fly to Durham from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Mississippi to Durham

Get recent, data-driven insights about flights from Mississippi to Durham including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Mississippi to Durham?

Currently, August is the cheapest month in which you can book a flight from Mississippi to Durham (average of $206). Flying from Mississippi to Durham in March is currently the most expensive (average of $316). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MS to DU8?

Find hourly flight availability from Mississippi to Durham. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 18, 2024.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Mississippi to Durham as you normally would.

Rainfall in Durham by month

Plan your trip to Durham by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Durham ranges from 2.9 - 4.7 inches per month. July is typically the wettest month, when rainfall can reach 4.7 in. April is typically the driest time to visit Durham when rainfall is around 2.9 in.

Temperature in Durham by month

Plan your trip to Durham by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Durham, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 41.0 F).

Reviews of airlines servicing Durham

Get insights into the airlines that provide service to Durham. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Durham. Reviews last updated December 18, 2024.
See what other customers who have flown with Delta, American Airlines and United Airlines from Mississippi to Durham have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
4,848 reviews

Comfort

8.1

Crew

8.7

Overall

8.1

Food

7.2

Boarding

8.2

Entertainment

7.7

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Southwest
8.1
Very good
4,848 reviews
Southwest
8.1
Very good
4,848 reviews

Comfort

8.1

Crew

8.7

Overall

8.1

Food

7.2

Boarding

8.2

Entertainment

7.7

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Delta
8.0
Very good
8,604 reviews
Southwest
8.1
Very good
4,848 reviews

Comfort

8.1

Crew

8.7

Overall

8.1

Food

7.2

Boarding

8.2

Entertainment

7.7

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

United Airlines
7.4
Good
9,055 reviews
Southwest
8.1
Very good
4,848 reviews

Comfort

8.1

Crew

8.7

Overall

8.1

Food

7.2

Boarding

8.2

Entertainment

7.7

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

American Airlines
7.2
Good
10,000 reviews
Southwest
8.1
Very good
4,848 reviews

Comfort

8.1

Crew

8.7

Overall

8.1

Food

7.2

Boarding

8.2

Entertainment

7.7

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Spirit Airlines
6.3
Okay
8,119 reviews
Southwest
8.1
Very good
4,848 reviews

Comfort

8.1

Crew

8.7

Overall

8.1

Food

7.2

Boarding

8.2

Entertainment

7.7

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Related info for your journey

Find useful and relevant information for your journey from Mississippi to Durham. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Mississippi to Durham one-way?

    To fly one-way, consider booking your trip with Delta, which is currently one of the cheapest options available, starting at $149. American Airlines flights start at $169 while deals on Southwest start at $394 one-way.

  • What are the most popular routes from Mississippi to Durham?

    The most popular route from Mississippi to Durham is Memphis - Raleigh-Durham. You may also consider Gulfport Biloxi Regional - Raleigh-Durham or Jackson-Evers Intl - Raleigh-Durham.

  • Can I find deals for flights from Mississippi to Durham that include hotel bookings?

    Yes. In addition to deals on Mississippi to Durham flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to Durham?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to Durham.

  • Can I find deals for business class flights from Mississippi to Durham?

    Yes. Cheapflights offers flight deals from Mississippi to Durham by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mississippi to Durham?

    Currently, August is the cheapest month in which you can book a flight from Mississippi to Durham (average of $206). Flying from Mississippi to Durham in March is currently the most expensive (average of $316). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Mississippi to Durham

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to Charlotte flights
Newark to Raleigh flights
Newark to Charlotte flights
LaGuardia to Raleigh flights
LaGuardia to Charlotte flights
Boston to Charlotte flights
John F Kennedy Intl to Raleigh flights
Minneapolis to Charlotte flights
Dallas/Fort Worth to Charlotte flights
Boston to Raleigh flights
Los Angeles to Charlotte flights
O'Hare Intl to Charlotte flights
Newark to Myrtle Beach flights
O'Hare Intl to Raleigh flights
Hobby to Charlotte flights
Los Angeles to Raleigh flights
Seattle to Raleigh flights
John F Kennedy Intl to Myrtle Beach flights
Dulles Intl to Charlotte flights
Orlando to Raleigh flights
Dallas/Fort Worth to Raleigh flights
LaGuardia to Myrtle Beach flights
Fort Lauderdale to Charlotte flights
Philadelphia to Charlotte flights
Denver to Charlotte flights
George Bush Intcntl to Charlotte flights
Baltimore to Charlotte flights
San Francisco to Raleigh flights
Miami to Charlotte flights
Reagan-National to Charlotte flights
Seattle to Charlotte flights
Fort Lauderdale to Raleigh flights
Detroit to Charlotte flights
Hobby to Raleigh flights
Denver to Raleigh flights
San Francisco to Charlotte flights
Minneapolis to Raleigh flights
Atlanta to Raleigh flights
LaGuardia to Greensboro flights
O'Hare Intl to Knoxville flights
Boston to Myrtle Beach flights
Miami to Raleigh flights
Newark to Greensboro flights
Detroit to Myrtle Beach flights
George Bush Intcntl to Raleigh flights
Orlando to Charlotte flights
John F Kennedy Intl to Greensboro flights
Detroit to Raleigh flights
Newark to Asheville flights
Newark to Norfolk flights

Top 2 airlines flying from Mississippi to Durham

Discover the top 2 airlines that operate flights from Mississippi to Durham. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2024.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$196Average$380FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$206Average$451FlexibilityNo cancel feeOn-time71%
100% Free
Cheapflights is completely free to use, so you can start saving the moment you arrive.
Book with Flexibility
Our users can plan ahead with confidence and find flights with no change fees
Travel Smart
Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.