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Durham

$85+ Cheap flights from Mississippi to Durham, NC

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/11. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — RDU
Apr 8 — Apr 151
Tue 4/8
Tue 4/15
1 adult, Economy
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Cheap flight deals from Mississippi to Durham

Keep the following information in mind while searching for Mississippi to Durham flight deals. Data was last updated April 3, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$161
(Expedia)

One-way from

$85
(Mytrip)

Popular in

October

Cheapest in

September

Average price

$350
Provider with most accurate pricing for Jackson-Evers Intl-Raleigh-Durham flight deals.
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Provider most trusted by Cheapflights users for Jackson-Evers Intl-Raleigh-Durham flights.
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From Mississippi to Durham
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One-way flight from Mississippi to Durham
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High demand for flights, 3% potential price rise
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Cheapest flight prices on average. 3% potential price decrease ($12 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from Mississippi to Durham

Cheapest flights from Mississippi to Durham
Explore the most affordable flight options available from Mississippi to Durham. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 3, 2025.

This Expedia deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/151:14 pmMEM - RDU
1 stop4h 36mMultiple Airlines
Mon 5/198:33 amRDU - MEM
Nonstop2h 10mMultiple Airlines
Deal found 4/2$161
This American Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/306:21 pmGPT - RDU
1 stop4h 37mAmerican Airlines
Sat 5/318:27 pmRDU - GPT
1 stop4h 31mAmerican Airlines
Deal found 4/2$199
This Mytrip deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/156:34 pmMEM - RDU
1 stop13h 38mSpirit Airlines
Mon 5/1910:17 amRDU - MEM
2 stops31h 02mSpirit Airlines
Deal found 4/2$224
This Delta deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/104:37 pmBTR - RDU
1 stop6h 42mDelta
Sun 5/256:29 amRDU - BTR
1 stop4h 05mDelta
Deal found 4/2$243
This Delta deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/27:16 pmMEM - RDU
1 stop3h 43mDelta
Sun 5/45:20 amRDU - MEM
1 stop5h 13mDelta
Deal found 4/2$249
This Delta deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/1211:00 amGPT - RDU
1 stop3h 43mDelta
Sat 7/195:25 amRDU - GPT
1 stop5h 39mDelta
Deal found 4/2$249
This American Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/167:09 amBTR - RDU
1 stop4h 36mAmerican Airlines
Wed 4/233:24 pmRDU - BTR
1 stop8h 21mAmerican Airlines
Deal found 4/2$254
This American Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/186:36 pmMOB - RDU
1 stop4h 22mAmerican Airlines
Tue 4/224:18 pmRDU - MOB
1 stop6h 07mAmerican Airlines
Deal found 4/2$255
This United Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/162:05 pmBTR - RDU
1 stop7h 08mUnited Airlines
Sun 4/206:10 amRDU - BTR
1 stop6h 02mUnited Airlines
Deal found 4/1$259
This Southwest deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/254:25 pmMEM - RDU
1 stop5h 25mSouthwest
Tue 5/276:15 amRDU - MEM
1 stop4h 55mSouthwest
Deal found 4/2$274
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/92:26 pmMEM - RDU
1 stop6h 34mAmerican Airlines
Sun 5/115:00 amRDU - MEM
1 stop4h 40mAmerican Airlines
Deal found 4/1$283
This United Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/287:30 amMEM - RDU
1 stop5h 42mUnited Airlines
Mon 9/16:30 amRDU - MEM
1 stop5h 28mUnited Airlines
Deal found 4/2$287

Cheapflights Fare Finder

Customize your flight search to find flights from Mississippi to Durham that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 3, 2025.
Use the filters below to find and compare flights from Mississippi to Durham that are best for you.

Fly from

Mississippi

Fly to

Durham

Route

Depart

Return

Price

MemphisRaleigh

MEM - RDU

MEMRDU

Memphis

Thu 5/15

1:14 pm-6:50 pm

1 stop4h 36m

Raleigh-Durham

Mon 5/19

8:33 am-9:43 am

Nonstop2h 10m

$161

GulfportRaleigh

GPT - RDU

GPTRDU

Gulfport Biloxi Regional

Fri 5/30

6:21 pm-11:58 pm

1 stop4h 37m

Raleigh-Durham

Sat 5/31

8:27 pm-11:58 pm

1 stop4h 31m

$199

MemphisRaleigh

MEM - RDU

MEMRDU

Memphis

Thu 5/15

6:34 pm-9:12 am

1 stop13h 38m

Raleigh-Durham

Mon 5/19

10:17 am-4:19 pm

2 stops31h 02m

$224

Baton RougeRaleigh

BTR - RDU

BTRRDU

Baton Rouge Ryan

Sat 5/10

4:37 pm-12:19 am

1 stop6h 42m

Raleigh-Durham

Sun 5/25

6:29 am-9:34 am

1 stop4h 05m

$243

MemphisRaleigh

MEM - RDU

MEMRDU

Memphis

Fri 5/2

7:16 pm-11:59 pm

1 stop3h 43m

Raleigh-Durham

Mon 5/5

7:59 pm-11:17 pm

1 stop4h 18m

$249

GulfportRaleigh

GPT - RDU

GPTRDU

Gulfport Biloxi Regional

Sat 7/12

11:00 am-3:43 pm

1 stop3h 43m

Raleigh-Durham

Sat 7/19

5:25 am-10:04 am

1 stop5h 39m

$249

Baton RougeRaleigh

BTR - RDU

BTRRDU

Baton Rouge Ryan

Wed 4/16

7:09 am-12:45 pm

1 stop4h 36m

Raleigh-Durham

Wed 4/23

3:24 pm-10:45 pm

1 stop8h 21m

$254

MobileRaleigh

MOB - RDU

MOBRDU

Mobile

Fri 4/18

6:36 pm-11:58 pm

1 stop4h 22m

Raleigh-Durham

Tue 4/22

4:18 pm-9:25 pm

1 stop6h 07m

$255

Baton RougeRaleigh

BTR - RDU

BTRRDU

Baton Rouge Ryan

Wed 4/16

2:05 pm-10:13 pm

1 stop7h 08m

Raleigh-Durham

Sun 4/20

6:10 am-11:12 am

1 stop6h 02m

$259

MemphisRaleigh

MEM - RDU

MEMRDU

Memphis

Fri 4/25

4:25 pm-10:50 pm

1 stop5h 25m

Raleigh-Durham

Tue 5/27

6:15 am-10:10 am

1 stop4h 55m

$274

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/2

Showing 1-10 of 35 results
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Best time to book a flight from Mississippi to Durham

Have a flexible travel schedule? Discover the best time to fly to Durham from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to Durham

What is the cheapest month to book a flight from Mississippi to Durham?

Currently, August is the cheapest month in which you can book a flight from Mississippi to Durham (average of $206). Flying from Mississippi to Durham in March is currently the most expensive (average of $295). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MS to DU8?

Find hourly flight availability from Mississippi to Durham. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 3, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Mississippi to Durham as you normally would.

Rainfall in Durham by month

Plan your trip to Durham by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Durham ranges from 2.9 - 4.7 inches per month. July is typically the wettest month, when rainfall can reach 4.7 in. April is typically the driest time to visit Durham when rainfall is around 2.9 in.

Temperature in Durham by month

Plan your trip to Durham by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Durham, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 41.0 F).

Reviews of airlines servicing Durham

Get insights into the airlines that provide service to Durham. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Durham. Reviews last updated April 3, 2025.
See what other customers who have flown with Breeze Airways, Southwest and Delta from Mississippi to Durham have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Breeze Airways
8.1
Very good
157 reviews

Crew

8.8

Overall

8.1

Entertainment

6.6

Comfort

8.2

Food

6.7

Boarding

8.3

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!
Breeze Airways
8.1
Very good
157 reviews
Breeze Airways
8.1
Very good
157 reviews

Crew

8.8

Overall

8.1

Entertainment

6.6

Comfort

8.2

Food

6.7

Boarding

8.3

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!
Southwest
8.0
Very good
4,274 reviews
Breeze Airways
8.1
Very good
157 reviews

Crew

8.8

Overall

8.1

Entertainment

6.6

Comfort

8.2

Food

6.7

Boarding

8.3

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!
Delta
8.0
Very good
7,897 reviews
Breeze Airways
8.1
Very good
157 reviews

Crew

8.8

Overall

8.1

Entertainment

6.6

Comfort

8.2

Food

6.7

Boarding

8.3

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!
United Airlines
7.4
Good
8,619 reviews
Breeze Airways
8.1
Very good
157 reviews

Crew

8.8

Overall

8.1

Entertainment

6.6

Comfort

8.2

Food

6.7

Boarding

8.3

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!
American Airlines
7.2
Good
10,000 reviews
Breeze Airways
8.1
Very good
157 reviews

Crew

8.8

Overall

8.1

Entertainment

6.6

Comfort

8.2

Food

6.7

Boarding

8.3

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!

Related info for your journey

Find useful and relevant information for your journey from Mississippi to Durham. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Mississippi to Durham one-way?

    To fly one-way, consider booking your trip with Spirit Airlines, which is currently one of the cheapest options available, starting at $85. American Airlines flights start at $125 while deals on Delta start at $249 one-way.

  • What are the most popular routes from Mississippi to Durham?

    The most popular route from Mississippi to Durham is Memphis - Raleigh-Durham. You may also consider Mobile - Raleigh-Durham or Baton Rouge Ryan - Raleigh-Durham.

  • Can I find deals for flights from Mississippi to Durham that include hotel bookings?

    Yes. In addition to deals on Mississippi to Durham flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to Durham?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to Durham.

  • Can I find deals for business class flights from Mississippi to Durham?

    Yes. Cheapflights offers flight deals from Mississippi to Durham by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mississippi to Durham?

    Currently, August is the cheapest month in which you can book a flight from Mississippi to Durham (average of $206). Flying from Mississippi to Durham in March is currently the most expensive (average of $295). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Mississippi to Durham

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Mississippi to Durham

Discover the top 2 airlines that operate flights from Mississippi to Durham. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 3, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$196Average$361FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$198Average$430FlexibilityNo cancel feeOn-time71%

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