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Durham

$106+ Cheap flights from Mississippi to Durham, NC

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/20. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — RDU
Feb 4 — Feb 111
Tue 2/4
Tue 2/11
1 adult, Economy
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Cheap flight deals from Mississippi to Durham

Discover tips and strategies to find the most affordable flight options for your journey from Mississippi (USMS) to Durham (DU8). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 30, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$224
(American Airlines)

One-way from

$106
(Mytrip)

Popular in

October

Cheapest in

September

Average price

$341
Provider with most accurate pricing for Jackson-Evers Intl-Raleigh-Durham flight deals.
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Provider most trusted by Cheapflights users for Jackson-Evers Intl-Raleigh-Durham flights.
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From Mississippi to Durham
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One-way flight from Mississippi to Durham
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High demand for flights, 6% potential price rise
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Cheapest flight prices on average. 2% potential price decrease ($11 potential savings vs. average RT price).
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Average for round-trip flights in January 2025
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Find flight deals from Mississippi to Durham

Cheapest flights from Mississippi to Durham
Explore the most affordable flight options available from Mississippi to Durham. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 30, 2025.

This American Airlines deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/1512:50 pmGPT - RDU
1 stop5h 26mAmerican Airlines
Sun 2/234:18 pmRDU - GPT
1 stop6h 48mAmerican Airlines
Deal found 1/29$224
This Delta deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/156:30 amGPT - RDU
1 stop4h 06mDelta
Sat 2/225:45 pmRDU - GPT
1 stop4h 07mDelta
Deal found 1/30$237
This Southwest deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/135:50 pmMEM - RDU
1 stop4h 30mSouthwest
Mon 3/175:30 amRDU - MEM
1 stop3h 50mSouthwest
Deal found 1/30$257
This FlightHub deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/298:04 amMEM - RDU
1 stop11h 44mSpirit Airlines
Sun 3/3010:58 amRDU - MEM
1 stop13h 54mSpirit Airlines
Deal found 1/30$258
This Delta deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/136:05 amBTR - RDU
1 stop4h 31mDelta
Mon 2/176:47 pmRDU - BTR
1 stop4h 36mDelta
Deal found 1/29$259
This American Airlines deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/256:22 pmBTR - RDU
1 stop5h 11mAmerican Airlines
Sun 4/275:05 amRDU - BTR
1 stop5h 39mAmerican Airlines
Deal found 1/30$284
This American Airlines deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/95:03 amJAN - RDU
1 stop4h 22mAmerican Airlines
Mon 4/148:20 pmRDU - JAN
1 stop4h 34mAmerican Airlines
Deal found 1/30$287
This American Airlines deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/235:11 amMEM - RDU
1 stop5h 45mAmerican Airlines
Sun 4/278:20 pmRDU - MEM
1 stop4h 10mAmerican Airlines
Deal found 1/29$302
This United Airlines deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/19:15 amMOB - RDU
1 stop5h 45mUnited Airlines
Sat 4/51:20 pmRDU - MOB
1 stop7h 22mUnited Airlines
Deal found 1/29$314
This Delta deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/167:15 amJAN - RDU
1 stop5h 53mDelta
Sun 4/206:35 amRDU - JAN
1 stop5h 46mDelta
Deal found 1/30$317
This American Airlines deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/35:20 amMOB - RDU
1 stop4h 09mAmerican Airlines
Sun 4/64:18 pmRDU - MOB
1 stop6h 08mAmerican Airlines
Deal found 1/29$329
This Mytrip deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/38:41 pmMEM - RDU
2 stops20h 54mMultiple Airlines
Sun 4/69:53 pmRDU - MEM
2 stops22h 24mMultiple Airlines
Deal found 1/30$330

Find flights from Mississippi to Durham within your budget

Customize your flight search to find flights from Mississippi to Durham that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 30, 2025.

Fly from

Any airport

Fly to

Any airport

Route

Depart

Return

Price

GulfportRaleigh

GPT - RDU

GPTRDU

Gulfport Biloxi Regional

Sat 2/15

12:50 pm-7:16 pm

1 stop5h 26m

Raleigh-Durham

Sun 2/23

4:18 pm-10:06 pm

1 stop6h 48m

$224

GulfportRaleigh

GPT - RDU

GPTRDU

Gulfport Biloxi Regional

Sat 2/15

6:30 am-11:36 am

1 stop4h 06m

Raleigh-Durham

Sat 2/22

5:45 pm-8:52 pm

1 stop4h 07m

$237

MemphisRaleigh

MEM - RDU

MEMRDU

Memphis

Thu 3/13

5:50 pm-11:20 pm

1 stop4h 30m

Raleigh-Durham

Mon 3/17

5:30 am-8:20 am

1 stop3h 50m

$257

MemphisRaleigh

MEM - RDU

MEMRDU

Memphis

Sat 3/29

8:04 am-8:48 pm

1 stop11h 44m

Raleigh-Durham

Sun 3/30

10:58 am-11:52 pm

1 stop13h 54m

$258

Baton RougeRaleigh

BTR - RDU

BTRRDU

Baton Rouge Ryan

Thu 2/13

6:05 am-11:36 am

1 stop4h 31m

Raleigh-Durham

Mon 2/17

6:47 pm-10:23 pm

1 stop4h 36m

$259

Baton RougeRaleigh

BTR - RDU

BTRRDU

Baton Rouge Ryan

Fri 4/25

6:22 pm-12:33 am

1 stop5h 11m

Raleigh-Durham

Sun 4/27

5:05 am-9:44 am

1 stop5h 39m

$284

JacksonRaleigh

JAN - RDU

JANRDU

Jackson-Evers Intl

Wed 4/9

5:03 am-10:25 am

1 stop4h 22m

Raleigh-Durham

Mon 4/14

8:20 pm-11:54 pm

1 stop4h 34m

$287

MemphisRaleigh

MEM - RDU

MEMRDU

Memphis

Wed 4/23

5:11 am-11:56 am

1 stop5h 45m

Raleigh-Durham

Sun 4/27

8:20 pm-11:30 pm

1 stop4h 10m

$302

MobileRaleigh

MOB - RDU

MOBRDU

Mobile

Tue 4/1

9:15 am-4:00 pm

1 stop5h 45m

Raleigh-Durham

Sat 4/5

1:20 pm-7:42 pm

1 stop7h 22m

$314

JacksonRaleigh

JAN - RDU

JANRDU

Jackson-Evers Intl

Wed 4/16

7:15 am-2:08 pm

1 stop5h 53m

Raleigh-Durham

Sun 4/20

6:35 am-11:21 am

1 stop5h 46m

$317

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/30

Showing 1-10 of 34 results
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Best time to book a flight from Mississippi to Durham

Have a flexible travel schedule? Discover the best time to fly to Durham from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Mississippi to Durham

Get recent, data-driven insights about flights from Mississippi to Durham including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Mississippi to Durham?

Currently, August is the cheapest month in which you can book a flight from Mississippi to Durham (average of $206). Flying from Mississippi to Durham in March is currently the most expensive (average of $316). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MS to DU8?

Find hourly flight availability from Mississippi to Durham. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 30, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Mississippi to Durham as you normally would.

Rainfall in Durham by month

Plan your trip to Durham by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Durham ranges from 2.9 - 4.7 inches per month. July is typically the wettest month, when rainfall can reach 4.7 in. April is typically the driest time to visit Durham when rainfall is around 2.9 in.

Temperature in Durham by month

Plan your trip to Durham by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Durham, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 41.0 F).

Reviews of airlines servicing Durham

Get insights into the airlines that provide service to Durham. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Durham. Reviews last updated January 30, 2025.
See what other customers who have flown with Southwest, Delta and United Airlines from Mississippi to Durham have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
4,585 reviews

Boarding

8.2

Comfort

8.1

Entertainment

7.7

Crew

8.7

Overall

8.1

Food

7.1

Reviews

1 / 20

6.0
Good

Lauren,Dec 2024

MCI - DCA

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Southwest
8.1
Very good
4,585 reviews
Southwest
8.1
Very good
4,585 reviews

Boarding

8.2

Comfort

8.1

Entertainment

7.7

Crew

8.7

Overall

8.1

Food

7.1

Reviews

1 / 20

6.0
Good

Lauren,Dec 2024

MCI - DCA

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Delta
8.0
Very good
8,450 reviews
Southwest
8.1
Very good
4,585 reviews

Boarding

8.2

Comfort

8.1

Entertainment

7.7

Crew

8.7

Overall

8.1

Food

7.1

Reviews

1 / 20

6.0
Good

Lauren,Dec 2024

MCI - DCA

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

United Airlines
7.4
Good
8,906 reviews
Southwest
8.1
Very good
4,585 reviews

Boarding

8.2

Comfort

8.1

Entertainment

7.7

Crew

8.7

Overall

8.1

Food

7.1

Reviews

1 / 20

6.0
Good

Lauren,Dec 2024

MCI - DCA

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

American Airlines
7.2
Good
10,000 reviews
Southwest
8.1
Very good
4,585 reviews

Boarding

8.2

Comfort

8.1

Entertainment

7.7

Crew

8.7

Overall

8.1

Food

7.1

Reviews

1 / 20

6.0
Good

Lauren,Dec 2024

MCI - DCA

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Spirit Airlines
6.3
Okay
8,083 reviews
Southwest
8.1
Very good
4,585 reviews

Boarding

8.2

Comfort

8.1

Entertainment

7.7

Crew

8.7

Overall

8.1

Food

7.1

Reviews

1 / 20

6.0
Good

Lauren,Dec 2024

MCI - DCA

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Related info for your journey

Find useful and relevant information for your journey from Mississippi to Durham. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Mississippi to Durham one-way?

    To fly one-way, consider booking your trip with Delta, which is currently one of the cheapest options available, starting at $144. American Airlines flights start at $149 while deals on Southwest start at $169 one-way.

  • What are the most popular routes from Mississippi to Durham?

    The most popular route from Mississippi to Durham is Memphis - Raleigh-Durham. You may also consider Baton Rouge Ryan - Raleigh-Durham or Jackson-Evers Intl - Raleigh-Durham.

  • Can I find deals for flights from Mississippi to Durham that include hotel bookings?

    Yes. In addition to deals on Mississippi to Durham flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to Durham?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to Durham.

  • Can I find deals for business class flights from Mississippi to Durham?

    Yes. Cheapflights offers flight deals from Mississippi to Durham by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mississippi to Durham?

    Currently, August is the cheapest month in which you can book a flight from Mississippi to Durham (average of $206). Flying from Mississippi to Durham in March is currently the most expensive (average of $316). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Mississippi to Durham

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Mississippi to Durham

Discover the top 2 airlines that operate flights from Mississippi to Durham. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$196Average$366FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$198Average$445FlexibilityNo cancel feeOn-time71%
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