HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Des Moines

$110+ Cheap flights from Spartanburg, SC to Des Moines (DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/29. Fares are subject to change and may not be available on all flights or dates of travel.
CLT — DSM
abr. 7 — abr. 141
lun. 4/7
lun. 4/14
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Spartanburg to Des Moines with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Spartanburg to Des Moines are usually found in September or October, booked 43 days in advance, depart on a Tuesday or Thursday and return on a Tuesday

Cheap flight deals from Spartanburg to Des Moines

Keep the following information in mind while searching for Spartanburg to Des Moines flight deals. Data was last updated abril 2, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$259
(Mytrip)

One-way from

$110
(Booking.com)

Popular in

June

Cheapest in

September

Average price

$399
Provider with most accurate pricing for Charlotte Douglas-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Charlotte Douglas-Des Moines flights.
Search Deals
From Spartanburg to Des Moines
Search Deals
One-way flight from Spartanburg to Des Moines
Search Deals
Highest demand for flights based on searches. 4% potential increase in price ($20 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 0% potential price decrease ($5 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2025
Search Deals

Find flight deals from Spartanburg to Des Moines

Cheapest flights from Spartanburg to Des Moines
Explore the most affordable flight options available from Spartanburg to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on abril 2, 2025.

This Mytrip deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 5/2211:58 amCLT - DSM
1 stop25h 48mMultiple Airlines
lun. 5/265:25 pmDSM - CLT
2 stops27h 35mMultiple Airlines
Deal found 4/1$259
This Mytrip deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 6/105:34 pmCLT - DSM
1 stop27h 19mFrontier
sáb. 6/148:38 pmDSM - CLT
1 stop18h 56mFrontier
Deal found 3/31$263
This Delta deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 5/145:40 amCLT - DSM
1 stop6h 01mDelta
mié. 5/215:35 amDSM - CLT
1 stop5h 59mDelta
Deal found 3/31$307
This Southwest deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 5/13:15 pmCLT - DSM
2 stops8h 50mSouthwest
mar. 5/66:40 amDSM - CLT
1 stop10h 05mSouthwest
Deal found 3/31$337
This United Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 4/245:32 pmCLT - DSM
1 stop5h 20mUnited Airlines
vie. 4/258:00 amDSM - CLT
1 stop6h 48mUnited Airlines
Deal found 4/1$358
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 5/1410:27 pmCLT - DSM
Nonstop2h 31mAmerican Airlines
mié. 5/216:45 amDSM - CLT
Nonstop2h 20mAmerican Airlines
Deal found 4/1$373

Cheapflights Fare Finder

Customize your flight search to find flights from Spartanburg to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated abril 2, 2025.
Use the filters below to find and compare flights from Spartanburg to Des Moines that are best for you.

Fly from

Spartanburg

Fly to

Des Moines

Route

Depart

Return

Price

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

jue. 5/22

11:58 am-12:46 pm

1 stop25h 48m

Des Moines

lun. 5/26

5:25 pm-10:00 pm

2 stops27h 35m

$259

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

mar. 6/10

5:34 pm-7:53 pm

1 stop27h 19m

Des Moines

sáb. 6/14

8:38 pm-4:34 pm

1 stop18h 56m

$263

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

mié. 5/14

5:40 am-10:41 am

1 stop6h 01m

Des Moines

mié. 5/21

5:35 am-12:34 pm

1 stop5h 59m

$307

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

jue. 5/1

3:15 pm-11:05 pm

2 stops8h 50m

Des Moines

mar. 5/6

6:40 am-5:45 pm

1 stop10h 05m

$337

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

jue. 4/24

5:32 pm-9:52 pm

1 stop5h 20m

Des Moines

vie. 4/25

8:00 am-3:48 pm

1 stop6h 48m

$358

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

mié. 5/14

10:27 pm-11:58 pm

Nonstop2h 31m

Des Moines

mié. 5/21

6:45 am-10:05 am

Nonstop2h 20m

$373

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

mar. 4/29

4:52 pm-6:37 pm

1 stop26h 45m

$110

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

dom. 5/18

9:02 pm-3:53 pm

1 stop19h 51m

$117

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

lun. 4/28

6:04 am-9:37 am

1 stop4h 33m

$173

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

sáb. 5/17

10:27 pm-11:58 pm

Nonstop2h 31m

$200

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/30

Showing 1-10 of 12 results
1
2

Best time to book a flight from Spartanburg to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Spartanburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Spartanburg to Des Moines

How far ahead should I book a flight from Spartanburg to Des Moines?

Use this chart to determine the optimal time to book a round-trip flight from Spartanburg to Des Moines. Price data was last updated on March 28, 2025.

To ensure you get the cheapest price possible for a flight from Spartanburg to Des Moines, you should look to book at least 43 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Spartanburg to Des Moines?

Currently, August is the cheapest month in which you can book a flight from Spartanburg to Des Moines (average of $336). Flying from Spartanburg to Des Moines in June is currently the most expensive (average of $422). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SB1 to DSM?

Find hourly flight availability from Spartanburg to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated abril 2, 2025.

When flying from Spartanburg to Des Moines, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

What is the cheapest day to fly from Spartanburg to Des Moines?

Use this chart to determine the cheapest time to fly round-trip from Spartanburg to Des Moines. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Spartanburg to Des Moines flight should consider departing on Tuesday mornings when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Rainfall in Des Moines by month

Plan your trip to Des Moines by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Des Moines ranges from 1.0 - 4.9 inches per month. June is typically the wettest month, when rainfall can reach 4.9 in. January is typically the driest time to visit Des Moines when rainfall is around 1.0 in.

Temperature in Des Moines by month

Plan your trip to Des Moines by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Des Moines, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 77.0 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 23.0 F).

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated abril 2, 2025.
Southwest
8.0
Very good
4,275 reviews

Food

7.1

Entertainment

7.6

Overall

8.0

Boarding

8.2

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Southwest
8.0
Very good
4,275 reviews
Southwest
8.0
Very good
4,275 reviews

Food

7.1

Entertainment

7.6

Overall

8.0

Boarding

8.2

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Delta
8.0
Very good
7,897 reviews
Southwest
8.0
Very good
4,275 reviews

Food

7.1

Entertainment

7.6

Overall

8.0

Boarding

8.2

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
United Airlines
7.4
Good
8,616 reviews
Southwest
8.0
Very good
4,275 reviews

Food

7.1

Entertainment

7.6

Overall

8.0

Boarding

8.2

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,275 reviews

Food

7.1

Entertainment

7.6

Overall

8.0

Boarding

8.2

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Frontier
6.0
Okay
3,277 reviews
Southwest
8.0
Very good
4,275 reviews

Food

7.1

Entertainment

7.6

Overall

8.0

Boarding

8.2

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.

Related info for your journey

Find useful and relevant information for your journey from Spartanburg to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Des Moines from Spartanburg?

    Located just 3.6 mi from the city center, Des Moines is the airport most travelers will use when flying to Des Moines from Spartanburg. Booking flights from Spartanburg to Des Moines (DSM) should be relatively easy as there is 1 daily inbound flight from Spartanburg from 3 different airlines.

  • What are the cheapest airlines to fly from Spartanburg to Des Moines one-way?

    The cheapest airline one-way is Frontier, with whom users have recently found tickets for as low as $110. However, be on the lookout for offers from Delta and American Airlines, as they are both options that can get you from Spartanburg to Des Moines for a low price.

  • What are the cheapest flights from Spartanburg to Des Moines?

    The cheapest flight price from Spartanburg to Des Moines is $121. On average you can expect to pay $315. The most popular route, (Charlotte Douglas - Des Moines), can usually be booked for $259.

  • Can I find deals for flights from Spartanburg to Des Moines that include hotel bookings?

    Yes. In addition to deals on Spartanburg to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Spartanburg to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Spartanburg to Des Moines.

  • Can I find deals for business class flights from Spartanburg to Des Moines?

    Yes. Cheapflights offers flight deals from Spartanburg to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Spartanburg to Des Moines?

    Currently, August is the cheapest month in which you can book a flight from Spartanburg to Des Moines (average of $336). Flying from Spartanburg to Des Moines in June is currently the most expensive (average of $422). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Spartanburg?

Book flights to Spartanburg if you plan to visit one of these locations
Ames
Altoona
Johnston
Boone
West Des Moines

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Spartanburg to Des Moines

See prices for flight routes from nearby airports that may be better suited for you.
Charlotte to Omaha flights
Charlotte to Des Moines flights
Greenville to Des Moines flights
Charleston to Cedar Rapids flights
Greenville to Omaha flights
Charlotte to Cedar Rapids flights
Charlotte to Moline flights
Charleston to Omaha flights
Savannah to Omaha flights
Charleston to Des Moines flights
Savannah to Des Moines flights
Greenville to Cedar Rapids flights
Columbia to Des Moines flights
Myrtle Beach to Omaha flights
Columbia to Omaha flights
Columbia to Moline flights
Columbia to Cedar Rapids flights
Myrtle Beach to Des Moines flights
Savannah to Cedar Rapids flights
Augusta to Moline flights
Charlotte to Waterloo flights
Greenville to Moline flights
Myrtle Beach to Cedar Rapids flights
Charlotte to Sioux City flights
Augusta to Omaha flights
Charlotte to Dubuque flights
Augusta to Cedar Rapids flights
Charleston to La Crosse flights
Hilton Head Island to Omaha flights
Hilton Head Island to Moline flights
Savannah to Sioux City flights
Savannah to Dubuque flights
Charlotte to La Crosse flights
Myrtle Beach to Moline flights
Charleston to Moline flights
Charleston to Dubuque flights
Columbia to Dubuque flights
Augusta to Des Moines flights

Top 3 airlines flying from Spartanburg to Des Moines

Discover the top 3 airlines that operate flights from Spartanburg to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated abril 2, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$198Average$370FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$228Average$390FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$323Average$479FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.