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Des Moines

$60+ Cheap flights from South Carolina to Des Moines (DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/24. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — DSM
Dec 27 — Jan 31
Fri 12/27
Fri 1/3
1 adult, Economy
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Cheap flight deals from South Carolina to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from South Carolina (USSC) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 22, 2024.

Round-trip from

$218
(Frontier)

One-way from

$60
(Frontier)
From South Carolina to Des Moines
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One-way flight from South Carolina to Des Moines
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Find flight deals from South Carolina to Des Moines

Cheapest flights from South Carolina to Des Moines
Explore the most affordable flight options available from South Carolina to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 22, 2024.

This Delta deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/256:00 amCLT - DSM
1 stop7h 25mDelta
Wed 12/255:35 pmDSM - CLT
1 stop4h 53mDelta
Deal found 12/21$392
This American Airlines deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/257:10 amCLT - DSM
1 stop6h 01mAmerican Airlines
Wed 12/251:58 pmDSM - CLT
Nonstop2h 32mAmerican Airlines
Deal found 12/21$467
This Delta deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/2410:56 amCAE - DSM
2 stops11h 20mDelta
Sat 1/46:30 pmDSM - CAE
1 stop4h 29mDelta
Deal found 12/21$518
This Southwest deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/234:05 pmCLT - DSM
1 stop7h 55mSouthwest
Mon 12/305:30 amDSM - CLT
2 stops13h 00mSouthwest
Deal found 12/22$574
This Mytrip deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/268:53 amCLT - DSM
1 stop14h 05mMultiple Airlines
Tue 12/313:16 pmDSM - CLT
2 stops18h 59mMultiple Airlines
Deal found 12/22$591
This United Airlines deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/245:15 pmCAE - DSM
1 stop5h 37mUnited Airlines
Sat 1/43:11 pmDSM - CAE
1 stop6h 57mUnited Airlines
Deal found 12/21$623
This Delta deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/247:27 amAGS - DSM
1 stop5h 58mDelta
Sat 1/46:30 pmDSM - AGS
1 stop4h 26mDelta
Deal found 12/21$685
This American Airlines deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/242:56 pmCHS - DSM
2 stops9h 30mAmerican Airlines
Mon 12/302:02 pmDSM - CHS
1 stop4h 38mAmerican Airlines
Deal found 12/21$755
This Delta deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/236:40 amCHS - DSM
1 stop5h 20mDelta
Fri 1/36:30 pmDSM - CHS
1 stop4h 28mDelta
Deal found 12/21$756
This United deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/265:25 pmCLT - DSM
1 stop5h 27mUnited Airlines
Mon 12/306:40 pmDSM - CLT
2 stops26h 34mUnited Airlines
Deal found 12/22$758
This Southwest deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/232:10 pmCHS - DSM
2 stops10h 45mSouthwest
Fri 1/35:50 amDSM - CHS
2 stops8h 35mSouthwest
Deal found 12/21$766
This American Airlines deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/245:00 amAGS - DSM
2 stops7h 33mAmerican Airlines
Sat 1/411:58 amDSM - AGS
2 stops9h 16mAmerican Airlines
Deal found 12/21$767

Find flights from South Carolina to Des Moines within your budget

Customize your flight search to find flights from South Carolina to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 22, 2024.

Fly from

Any airport

Fly to

Any airport

Route

Depart

Return

Price

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Fri 2/28

8:08 am-6:17 pm

1 stop11h 09m

Des Moines

Mon 3/3

7:17 pm-7:08 am

1 stop10h 51m

$218

ColumbiaDes Moines

CAE - DSM

CAEDSM

Columbia Metropolitan

Fri 2/21

7:20 am-12:21 pm

1 stop6h 01m

Des Moines

Mon 3/3

7:25 am-4:27 pm

1 stop8h 02m

$248

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Tue 3/25

6:00 am-10:23 am

1 stop5h 23m

Des Moines

Thu 3/27

6:30 pm-11:51 pm

1 stop4h 21m

$287

SavannahDes Moines

SAV - DSM

SAVDSM

Savannah/Hilton Head

Wed 1/8

4:55 pm-10:30 pm

1 stop6h 35m

Des Moines

Tue 1/14

8:00 am-5:49 pm

1 stop8h 49m

$296

SavannahDes Moines

SAV - DSM

SAVDSM

Savannah/Hilton Head

Tue 1/7

12:59 pm-7:05 pm

1 stop7h 06m

Des Moines

Wed 1/15

10:32 am-8:40 pm

2 stops9h 08m

$301

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Wed 1/8

8:29 pm-10:05 pm

Nonstop2h 36m

Des Moines

Thu 1/9

2:06 pm-5:26 pm

Nonstop2h 20m

$357

CharlestonDes Moines

CHS - DSM

CHSDSM

Charleston

Sat 1/4

6:58 am-10:22 am

1 stop4h 24m

Des Moines

Sat 1/11

2:06 pm-10:03 pm

1 stop6h 57m

$381

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Wed 1/8

6:20 am-7:00 pm

2 stops13h 40m

Des Moines

Thu 1/9

8:30 am-7:45 pm

2 stops10h 15m

$386

GreenvilleDes Moines

GSP - DSM

GSPDSM

Greenville

Thu 3/20

12:30 pm-5:49 pm

1 stop6h 19m

Des Moines

Tue 3/25

1:00 pm-10:00 pm

1 stop8h 00m

$386

CharlestonDes Moines

CHS - DSM

CHSDSM

Charleston

Fri 1/3

1:16 pm-2:11 pm

2 stops25h 55m

Des Moines

Sun 1/19

8:00 am-4:21 pm

1 stop7h 21m

$406

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/21

Showing 1-10 of 28 results
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Best time to book a flight from South Carolina to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from South Carolina to Des Moines

Get recent, data-driven insights about flights from South Carolina to Des Moines including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from South Carolina to Des Moines?

Currently, August is the cheapest month in which you can book a flight from South Carolina to Des Moines (average of $336). Flying from South Carolina to Des Moines in June is currently the most expensive (average of $422). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to DSM?

Find hourly flight availability from South Carolina to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 22, 2024.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from South Carolina to Des Moines as you normally would.

Rainfall in Des Moines by month

Plan your trip to Des Moines by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Des Moines ranges from 1.0 - 4.9 inches per month. June is typically the wettest month, when rainfall can reach 4.9 in. January is typically the driest time to visit Des Moines when rainfall is around 1.0 in.

Temperature in Des Moines by month

Plan your trip to Des Moines by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Des Moines, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 77.0 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 23.0 F).

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated December 22, 2024.
See what other customers who have flown with American Airlines, United Airlines and Delta from South Carolina to Des Moines have to say. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
4,804 reviews

Overall

8.1

Crew

8.7

Entertainment

7.7

Food

7.2

Boarding

8.2

Comfort

8.1

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Southwest
8.1
Very good
4,804 reviews
Southwest
8.1
Very good
4,804 reviews

Overall

8.1

Crew

8.7

Entertainment

7.7

Food

7.2

Boarding

8.2

Comfort

8.1

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Delta
8.0
Very good
8,594 reviews
Southwest
8.1
Very good
4,804 reviews

Overall

8.1

Crew

8.7

Entertainment

7.7

Food

7.2

Boarding

8.2

Comfort

8.1

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

United Airlines
7.4
Good
9,028 reviews
Southwest
8.1
Very good
4,804 reviews

Overall

8.1

Crew

8.7

Entertainment

7.7

Food

7.2

Boarding

8.2

Comfort

8.1

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

American Airlines
7.2
Good
10,000 reviews
Southwest
8.1
Very good
4,804 reviews

Overall

8.1

Crew

8.7

Entertainment

7.7

Food

7.2

Boarding

8.2

Comfort

8.1

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Frontier
6.1
Okay
3,472 reviews
Southwest
8.1
Very good
4,804 reviews

Overall

8.1

Crew

8.7

Entertainment

7.7

Food

7.2

Boarding

8.2

Comfort

8.1

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Des Moines from South Carolina?

    Des Moines (DSM) is the airport you will fly into if you book a flight from South Carolina to Des Moines. It is only a 3.6 mi journey from Des Moines (DSM) to Des Moines’s city center.

  • What are the cheapest airlines to fly from South Carolina to Des Moines one-way?

    One-way options have recently been found by users for as low as $60 on Frontier. Other airlines that offer cheap prices include American Airlines from $142 and Delta from $151 one-way.

  • What are the most popular routes from South Carolina to Des Moines?

    When deciding which route to take from South Carolina to Des Moines consider Charlotte Douglas - Des Moines, Columbia Metropolitan - Des Moines or Charleston - Des Moines as they are the most popular.

  • Can I find deals for flights from South Carolina to Des Moines that include hotel bookings?

    Yes. In addition to deals on South Carolina to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Des Moines.

  • Can I find deals for business class flights from South Carolina to Des Moines?

    Yes. Cheapflights offers flight deals from South Carolina to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Des Moines?

    Currently, August is the cheapest month in which you can book a flight from South Carolina to Des Moines (average of $336). Flying from South Carolina to Des Moines in June is currently the most expensive (average of $422). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Alternative routes for South Carolina to Des Moines

See prices for flight routes from nearby airports that may be better suited for you.
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LaGuardia to Cedar Rapids flights
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Newark to Moline flights
Boston to Des Moines flights
Raleigh to Moline flights
Hobby to Des Moines flights

Top 2 airlines flying from South Carolina to Des Moines

Discover the top 2 airlines that operate flights from South Carolina to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 22, 2024.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$188Average$424FlexibilityNo cancel feeOn-time71%
DeltaCheapest$198Average$370FlexibilityNo cancel feeOn-timeN/A
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