HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Des Moines

$134+ Cheap flights from South Carolina to Des Moines (DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/12. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — DSM
Nov 19 — Nov 261
Tue 11/19
Tue 11/26
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from South Carolina to Des Moines with Cheapflights

1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”
2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.
3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from South Carolina to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from South Carolina (USSC) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 14, 2024.

Find flight deals from South Carolina to Des Moines

Cheapest flights from South Carolina to Des Moines
Explore the most affordable flight options available from South Carolina to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 14, 2024.

This American Airlines deal was found by Cheapflights users on 11/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2111:54 amCLT - DSM
Nonstop2h 46mAmerican Airlines
Thu 11/286:55 amDSM - CLT
Nonstop2h 17mAmerican Airlines
Deal found 11/14$283
This Delta deal was found by Cheapflights users on 11/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2110:00 amCLT - DSM
1 stop4h 33mDelta
Thu 11/2812:12 pmDSM - CLT
1 stop5h 46mDelta
Deal found 11/14$302
This Delta deal was found by Cheapflights users on 11/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/65:15 amCHS - DSM
1 stop6h 18mDelta
Tue 12/105:50 amDSM - CHS
1 stop4h 29mDelta
Deal found 11/14$326
This Delta deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/62:21 pmGSP - DSM
1 stop4h 17mDelta
Tue 12/176:35 amDSM - GSP
1 stop4h 21mDelta
Deal found 11/13$331
This American Airlines deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/68:01 amGSP - DSM
1 stop6h 26mAmerican Airlines
Tue 12/174:00 pmDSM - GSP
2 stops6h 53mAmerican Airlines
Deal found 11/13$336
This Mytrip deal was found by Cheapflights users on 11/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/65:55 amCLT - DSM
1 stop17h 05mMultiple Airlines
Mon 12/96:42 pmDSM - CLT
2 stops26h 31mMultiple Airlines
Deal found 11/14$339
This United deal was found by Cheapflights users on 11/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/155:40 pmCLT - DSM
1 stop5h 06mUnited Airlines
Sat 1/181:49 pmDSM - CLT
1 stop8h 05mUnited Airlines
Deal found 11/14$374
This Mytrip deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/168:00 amSAV - DSM
1 stop6h 39mAllegiant Air
Sun 12/229:52 amDSM - SAV
1 stop11h 22mAllegiant Air
Deal found 11/12$379
This Southwest deal was found by Cheapflights users on 11/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/611:20 amCLT - DSM
2 stops8h 50mSouthwest
Sun 12/85:50 amDSM - CLT
2 stops10h 35mSouthwest
Deal found 11/14$450
This American Airlines deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/241:31 pmAGS - DSM
1 stop5h 53mAmerican Airlines
Sat 1/42:02 pmDSM - AGS
1 stop7h 12mAmerican Airlines
Deal found 11/13$450
This Southwest deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/241:50 pmSAV - DSM
2 stops8h 35mSouthwest
Sat 12/285:30 amDSM - SAV
2 stops10h 35mSouthwest
Deal found 11/13$460
This Delta deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/245:10 pmSAV - DSM
1 stop4h 36mDelta
Wed 12/255:50 amDSM - SAV
1 stop4h 34mDelta
Deal found 11/13$467

Find flights from South Carolina to Des Moines within your budget

Customize your flight search to find flights from South Carolina to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,752,363 searches. Data last updated November 14, 2024.

Fly from

Any airport

Fly to

Any airport

Route

Depart

Return

Price

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Sun 11/24

11:54 am-1:40 pm

Nonstop2h 46m

Des Moines

Fri 11/29

6:55 am-10:12 am

Nonstop2h 17m

$283

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Sun 11/24

2:14 pm-5:35 pm

1 stop4h 21m

Des Moines

Fri 11/29

10:26 am-5:47 pm

1 stop6h 21m

$302

CharlestonDes Moines

CHS - DSM

CHSDSM

Charleston

Fri 12/6

5:15 am-10:33 am

1 stop6h 18m

Des Moines

Tue 12/10

5:50 am-11:19 am

1 stop4h 29m

$326

GreenvilleDes Moines

GSP - DSM

GSPDSM

Greenville

Fri 12/6

2:21 pm-5:38 pm

1 stop4h 17m

Des Moines

Tue 12/17

6:35 am-11:56 am

1 stop4h 21m

$331

GreenvilleDes Moines

GSP - DSM

GSPDSM

Greenville

Fri 12/6

8:01 am-1:27 pm

1 stop6h 26m

Des Moines

Tue 12/17

4:00 pm-11:53 pm

2 stops6h 53m

$336

AugustaDes Moines

AGS - DSM

AGSDSM

Augusta Bush Field

Mon 2/3

7:21 pm-10:51 pm

1 stop4h 30m

Des Moines

Wed 2/5

6:30 pm-11:49 pm

1 stop4h 19m

$336

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Fri 12/6

5:55 am-10:00 pm

1 stop17h 05m

Des Moines

Mon 12/9

6:42 pm-10:13 pm

2 stops26h 31m

$339

AugustaDes Moines

AGS - DSM

AGSDSM

Augusta Bush Field

Mon 2/3

2:36 pm-11:01 pm

2 stops9h 25m

Des Moines

Wed 2/5

1:01 pm-9:33 pm

2 stops7h 32m

$346

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Sat 1/4

6:30 am-10:41 am

1 stop5h 11m

Des Moines

Sat 1/11

3:05 pm-10:15 pm

1 stop6h 10m

$355

Myrtle BeachDes Moines

MYR - DSM

MYRDSM

Myrtle Beach Intl

Mon 2/10

12:45 pm-7:18 pm

2 stops7h 33m

Des Moines

Thu 2/13

6:00 am-2:18 pm

1 stop7h 18m

$366

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/14

Showing 1-10 of 31 results
1
2
3
4

Best time to book a flight from South Carolina to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from South Carolina to Des Moines

Get recent, data-driven insights about flights from South Carolina to Des Moines including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from South Carolina to Des Moines?

Currently, September is the cheapest month in which you can book a flight from South Carolina to Des Moines (average of $311). Flying from South Carolina to Des Moines in June is currently the most expensive (average of $422). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to DSM?

Find hourly flight availability from South Carolina to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 14, 2024.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from South Carolina to Des Moines as you normally would.

Rainfall in Des Moines by month

Plan your trip to Des Moines by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Des Moines ranges from 1.0 - 4.9 inches per month. June is typically the wettest month, when rainfall can reach 4.9 in. January is typically the driest time to visit Des Moines when rainfall is around 1.0 in.

Temperature in Des Moines by month

Plan your trip to Des Moines by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Des Moines, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 77.0 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 23.0 F).

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated November 14, 2024.
See what other customers who have flown with Southwest, American Airlines and Delta from South Carolina to Des Moines have to say. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
5,045 reviews

Entertainment

7.7

Crew

8.7

Overall

8.1

Comfort

8.1

Food

7.2

Boarding

8.3

Reviews

1 / 10

Great service throughout our flight. Easy boarding with early bird check in

Southwest
8.1
Very good
5,045 reviews
Southwest
8.1
Very good
5,045 reviews

Entertainment

7.7

Crew

8.7

Overall

8.1

Comfort

8.1

Food

7.2

Boarding

8.3

Reviews

1 / 10

Great service throughout our flight. Easy boarding with early bird check in

Delta
8.0
Very good
8,788 reviews
Southwest
8.1
Very good
5,045 reviews

Entertainment

7.7

Crew

8.7

Overall

8.1

Comfort

8.1

Food

7.2

Boarding

8.3

Reviews

1 / 10

Great service throughout our flight. Easy boarding with early bird check in

United Airlines
7.4
Good
9,194 reviews
Southwest
8.1
Very good
5,045 reviews

Entertainment

7.7

Crew

8.7

Overall

8.1

Comfort

8.1

Food

7.2

Boarding

8.3

Reviews

1 / 10

Great service throughout our flight. Easy boarding with early bird check in

Allegiant Air
7.4
Good
856 reviews
Southwest
8.1
Very good
5,045 reviews

Entertainment

7.7

Crew

8.7

Overall

8.1

Comfort

8.1

Food

7.2

Boarding

8.3

Reviews

1 / 10

Great service throughout our flight. Easy boarding with early bird check in

American Airlines
7.2
Good
10,000 reviews
Southwest
8.1
Very good
5,045 reviews

Entertainment

7.7

Crew

8.7

Overall

8.1

Comfort

8.1

Food

7.2

Boarding

8.3

Reviews

1 / 10

Great service throughout our flight. Easy boarding with early bird check in

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Des Moines from South Carolina?

    Des Moines (DSM) is the airport you will fly into if you book a flight from South Carolina to Des Moines. It is only a 3.6 mi journey from Des Moines (DSM) to Des Moines’s city center.

  • What are the cheapest airlines to fly from South Carolina to Des Moines one-way?

    One-way options have recently been found by users for as low as $134 on United Airlines. Other airlines that offer cheap prices include Delta from $148 and American Airlines from $159 one-way.

  • What are the most popular routes from South Carolina to Des Moines?

    When deciding which route to take from South Carolina to Des Moines consider Charlotte Douglas - Des Moines, Charleston - Des Moines or Columbia Metropolitan - Des Moines as they are the most popular.

  • Can I find deals for flights from South Carolina to Des Moines that include hotel bookings?

    Yes. In addition to deals on South Carolina to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Des Moines.

  • Can I find deals for business class flights from South Carolina to Des Moines?

    Yes. Cheapflights offers flight deals from South Carolina to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Des Moines?

    Currently, September is the cheapest month in which you can book a flight from South Carolina to Des Moines (average of $311). Flying from South Carolina to Des Moines in June is currently the most expensive (average of $422). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for South Carolina to Des Moines

See prices for flight routes from nearby airports that may be better suited for you.
LaGuardia to Omaha flights
Denver to Des Moines flights
Denver to Cedar Rapids flights
John F Kennedy Intl to Omaha flights
O'Hare Intl to Omaha flights
Denver to Omaha flights
Los Angeles to Omaha flights
Reagan-National to Omaha flights
Minneapolis to Omaha flights
Newark to Omaha flights
Seattle to Des Moines flights
Atlanta to Omaha flights
LaGuardia to Des Moines flights
Hobby to Des Moines flights
Sky Harbor Intl to Des Moines flights
John F Kennedy Intl to Des Moines flights
Dallas/Fort Worth to Omaha flights
Atlanta to Des Moines flights
O'Hare Intl to Des Moines flights
Orlando to Des Moines flights
Dulles Intl to Omaha flights
Dallas/Fort Worth to Cedar Rapids flights
Salt Lake City to Omaha flights
San Francisco to Omaha flights
George Bush Intcntl to Des Moines flights
Portland to Omaha flights
Hobby to Omaha flights
Dallas/Fort Worth to Des Moines flights
O'Hare Intl to Cedar Rapids flights
Baltimore to Omaha flights
Ontario to Omaha flights
Dulles Intl to Cedar Rapids flights
Los Angeles to Cedar Rapids flights
Reagan-National to Cedar Rapids flights
Charlotte to Omaha flights
Boston to Cedar Rapids flights
Seattle to Omaha flights
San Diego to Omaha flights
Baltimore to Cedar Rapids flights
Sky Harbor Intl to Cedar Rapids flights
Boston to Omaha flights
Denver to Moline flights
Reagan-National to Des Moines flights
George Bush Intcntl to Omaha flights
Ontario to Cedar Rapids flights
Sky Harbor Intl to Omaha flights
Miami to Omaha flights
Raleigh to Des Moines flights
Salt Lake City to Des Moines flights
John F Kennedy Intl to Cedar Rapids flights

Top 2 airlines flying from South Carolina to Des Moines

Discover the top 2 airlines that operate flights from South Carolina to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,752,363 searches. Data last updated November 14, 2024.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$189Average$410FlexibilityNo cancel feeOn-time71%
DeltaCheapest$198Average$372FlexibilityNo cancel feeOn-timeN/A
100% Free
Cheapflights is completely free to use, so you can start saving the moment you arrive.
Book with Flexibility
Our users can plan ahead with confidence and find flights with no change fees
Travel Smart
Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.
View all available airlines