What are the cheapest airlines flying from San Antonio to Des Moines round-trip?

Currently priced at $284, Delta will fly you from San Antonio to Des Moines and back. In addition to Delta, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from American Airlines and United Airlines - these airlines can fly you to your destination from $289 and $303, respectively. Delta is priced at 36% lower than the current average price of a flight leaving 3 months from now.

What are the cheapest airlines to fly from San Antonio to Des Moines one-way?

$136 is the cheapest one-way deal found within the past few days, from American Airlines. You may also be able to find cheap deals on Delta and United Airlines, with prices starting from $152 and $263, respectively.

What is the cheapest day to fly from San Antonio to Des Moines?

Travelers seeking maximum savings on their San Antonio to Des Moines flight should consider departing on Tuesday mornings when fares are most often at their lowest. Friday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

What are the most popular airlines that fly from San Antonio to Des Moines?

Before booking your flight from San Antonio to Des Moines check out the most popular airlines for this route: American Airlines, Delta or Frontier.

What is the cheapest day to fly round-trip from San Antonio to Des Moines?

Monday is generally a great day to depart. Flying on this day could help you save up to 81%.

What is the cheapest month to fly from San Antonio to Des Moines?

July can be a great time to fly to Des Moines from San Antonio with a flight ticket averaging about $444. Cheapflights users have found deals in the month of July for as cheap as $220. The most expensive prices can be found in the month of December.

Most accurate provider : When it comes to deals on San Antonio-Des Moines flights, users find the pricing of Mytrip to be most consistent on Cheapflights vs. Mytrip Users can find the same prices on San Antonio-Des Moines flight deals on Cheapflights vs. Mytrip >95% of the time. Price accuracy is based on data collected from San Antonio-Des Moines flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on San Antonio-Des Moines flights, Cheapflights users trust Mytrip the most. Mytrip has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Antonio-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from San Antonio to Des Moines that include hotel bookings?

Yes. In addition to deals on San Antonio to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from San Antonio to Des Moines?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Antonio to Des Moines.

Can I find deals for business class flights from San Antonio to Des Moines?

Yes. Cheapflights offers flight deals from San Antonio to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$128+ Flights from San Antonio to Des Moines

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1. Tell us where you want to go

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Cheap flight deals from San Antonio to Des Moines

Most accurate provider	Mytrip 3 stars
Most trusted provider	Mytrip 3 stars
Round-trip from	$284 (Delta)
One-way from	$128 (eDestinos)
Popular in	December
Cheapest in	July
Average price	$368

Provider with most accurate pricing for San Antonio-Des Moines flight deals.

Search Deals

Provider most trusted by Cheapflights users for San Antonio-Des Moines flights.

Search Deals

From San Antonio to Des Moines

Search Deals

One-way flight from San Antonio to Des Moines

Search Deals

Highest demand for flights based on searches. 15% potential increase in price ($84 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 5% potential price decrease ($23 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in April 2025

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Find flight deals from San Antonio to Des Moines

Cheapest flights from San Antonio to Des Moines
Explore the most affordable flight options available from San Antonio to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 15, 2025.

Sat 5/172:38 pmSAT - DSM

1 stop6h 28mDelta

Sun 5/256:30 amDSM - SAT

1 stop6h 06mDelta

Deal found 4/15

$284

Sat 5/174:46 pmSAT - DSM

2 stops6h 53mAmerican Airlines

Sun 5/255:27 pmDSM - SAT

1 stop6h 31mAmerican Airlines

Deal found 4/15

$289

Mon 8/115:56 pmSAT - DSM

1 stop4h 21mUnited Airlines

Thu 8/146:24 amDSM - SAT

1 stop5h 21mUnited Airlines

Deal found 4/15

$303

Sat 5/172:37 pmSAT - DSM

2 stops24h 18mMultiple Airlines

Sun 5/257:00 amDSM - SAT

2 stops22h 04mMultiple Airlines

Deal found 4/15

$325

Thu 5/15:00 amSAT - DSM

1 stop6h 20mSouthwest

Tue 5/66:40 amDSM - SAT

2 stops11h 05mSouthwest

Deal found 4/15

$360

Best flights from San Antonio to Des Moines
Discover carefully curated flight deals from San Antonio to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 15, 2025.

Sat 5/172:38 pmSAT - DSM

1 stop6h 28mDelta

Sun 5/256:30 amDSM - SAT

1 stop6h 06mDelta

Deal found 4/15

$284

Sat 5/174:46 pmSAT - DSM

2 stops6h 53mAmerican Airlines

Sun 5/255:27 pmDSM - SAT

1 stop6h 31mAmerican Airlines

Deal found 4/15

$289

Mon 8/115:56 pmSAT - DSM

1 stop4h 21mUnited Airlines

Thu 8/146:24 amDSM - SAT

1 stop5h 21mUnited Airlines

Deal found 4/15

$303

Sat 5/172:37 pmSAT - DSM

2 stops24h 18mMultiple Airlines

Sun 5/257:00 amDSM - SAT

2 stops22h 04mMultiple Airlines

Deal found 4/15

$325

Thu 5/15:00 amSAT - DSM

1 stop6h 20mSouthwest

Tue 5/66:40 amDSM - SAT

2 stops11h 05mSouthwest

Deal found 4/15

$360

Last-minute flights from San Antonio to Des Moines
Discover last-minute flight deals from San Antonio to Des Moines. Data last updated April 15, 2025 and is based on user searches.

Wed 4/237:25 pmSAT - DSM

1 stop27h 16mMultiple Airlines

Sun 4/273:44 pmDSM - SAT

1 stop17h 48mMultiple Airlines

Deal found 4/15

$341

Fri 4/256:30 amSAT - DSM

1 stop4h 49mDelta

Mon 4/284:45 pmDSM - SAT

1 stop5h 55mDelta

Deal found 4/15

$647

Fri 4/259:35 amSAT - DSM

2 stops11h 04mUnited Airlines

Mon 4/288:00 amDSM - SAT

1 stop5h 22mUnited Airlines

Deal found 4/15

$652

Thu 5/15:00 amSAT - DSM

1 stop6h 20mSouthwest

Tue 5/66:40 amDSM - SAT

2 stops11h 05mSouthwest

Deal found 4/15

$360

Sat 5/172:38 pmSAT - DSM

1 stop6h 28mDelta

Sun 5/256:30 amDSM - SAT

1 stop6h 06mDelta

Deal found 4/15

$284

Sat 5/174:46 pmSAT - DSM

2 stops6h 53mAmerican Airlines

Sun 5/255:27 pmDSM - SAT

1 stop6h 31mAmerican Airlines

Deal found 4/15

$289

Sat 5/172:37 pmSAT - DSM

2 stops24h 18mMultiple Airlines

Sun 5/257:00 amDSM - SAT

2 stops22h 04mMultiple Airlines

Deal found 4/15

$325

Sat 5/242:10 pmSAT - DSM

1 stop7h 12mUnited Airlines

Mon 5/266:25 amDSM - SAT

1 stop5h 58mUnited Airlines

Deal found 4/15

$401

One-way flights from San Antonio to Des Moines
Search for one-way flight options from San Antonio to Des Moines. Find affordable one-way fares based on user searches. Data last updated April 15, 2025.

Thu 5/11:43 pmSAT - DSM

1 stop8h 58mMultiple Airlines

Deal found 4/15

$128

Tue 6/36:15 amSAT - DSM

1 stop7h 33mAmerican Airlines

Deal found 4/15

$136

Mon 6/26:25 amSAT - DSM

1 stop6h 02mDelta

Deal found 4/15

$152

Tue 6/37:00 pmSAT - DSM

2 stops19h 42mUnited Airlines

Deal found 4/15

$263

Thu 5/17:02 amSAT - DSM

3 stops16h 52mAlaska Airlines

Deal found 4/15

$1,224

Cheapflights Fare Finder

Use the filters below to find and compare flights from San Antonio to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

San AntonioDes Moines

SAT - DSM

SATDSM

San Antonio

Sat 5/17

2:38 pm-9:06 pm

1 stop6h 28m

Des Moines

Sun 5/25

6:30 am-12:36 pm

1 stop6h 06m

$284

San AntonioDes Moines

SAT - DSM

SATDSM

San Antonio

Sat 5/17

4:46 pm-11:39 pm

2 stops6h 53m

Des Moines

Sun 5/25

5:27 pm-11:58 pm

1 stop6h 31m

$289

San AntonioDes Moines

SAT - DSM

SATDSM

San Antonio

Mon 8/11

5:56 pm-10:17 pm

1 stop4h 21m

Des Moines

Thu 8/14

6:24 am-11:45 am

1 stop5h 21m

$303

San AntonioDes Moines

SAT - DSM

SATDSM

San Antonio

Sat 5/17

2:37 pm-2:55 pm

2 stops24h 18m

Des Moines

Sun 5/25

7:00 am-5:04 am

2 stops22h 04m

$325

San AntonioDes Moines

SAT - DSM

SATDSM

San Antonio

Thu 5/1

5:00 am-11:20 am

1 stop6h 20m

Des Moines

Tue 5/6

6:40 am-5:45 pm

2 stops11h 05m

$360

San AntonioDes Moines

SAT - DSM

SATDSM

San Antonio

Thu 5/1

1:43 pm-10:41 pm

1 stop8h 58m

$128

San AntonioDes Moines

SAT - DSM

SATDSM

San Antonio

Tue 6/3

6:15 am-1:48 pm

1 stop7h 33m

$136

San AntonioDes Moines

SAT - DSM

SATDSM

San Antonio

Mon 6/2

6:25 am-12:27 pm

1 stop6h 02m

$152

San AntonioDes Moines

SAT - DSM

SATDSM

San Antonio

Tue 6/3

7:00 pm-2:42 pm

2 stops19h 42m

$263

San AntonioDes Moines

SAT - DSM

SATDSM

San Antonio

Thu 5/1

7:02 am-11:54 pm

3 stops16h 52m

$1,224

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/15

Compare providers for flights from San Antonio to Des Moines

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Antonio to Des Moines in April.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy1 star	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*2 stars
eDreams	Price Accuracy3 stars	Trust Score*3 stars
Priceline	Price Accuracy1 star	Trust Score*3 stars
Mytrip	Price Accuracy3 stars	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on San Antonio-Des Moines flights, users find the pricing of Mytrip to be most consistent on Cheapflights vs. Mytrip Users can find the same prices on San Antonio-Des Moines flight deals on Cheapflights vs. Mytrip >95% of the time. Price accuracy is based on data collected from San Antonio-Des Moines flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on San Antonio-Des Moines flights, Cheapflights users trust Mytrip the most. Mytrip has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Antonio-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from San Antonio to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from San Antonio with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Antonio to Des Moines

What is the cheapest month to book a flight from San Antonio to Des Moines?

Currently, August is the cheapest month in which you can book a flight from San Antonio to Des Moines (average of $336). Flying from San Antonio to Des Moines in June is currently the most expensive (average of $422). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SAT to DSM?

One of the essential ways to save on airfare from San Antonio to Des Moines is to remain as flexible as possible. Flights that are in the afternoon tend to be the most expensive. A flight in the evening could potentially save you up to 40% on airfare.

Rainfall in Des Moines by month

In terms of precipitation, rainfall in Des Moines ranges from 1.0 - 4.9 inches per month. June is typically the wettest month, when rainfall can reach 4.9 in. January is typically the driest time to visit Des Moines when rainfall is around 1.0 in.

Temperature in Des Moines by month

If weather is an important factor for your trip to Des Moines, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 77.0 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 23.0 F).

Reviews of airlines servicing Des Moines

To help decide which airline to fly from San Antonio to Des Moines, see what other customers have to say about Alaska Airlines, Southwest and Delta. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Alaska Airlines

8.0

Very good

9,871 reviews

Reviews

1 / 20

4.0

Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >

Alaska Airlines

8.0

Very good

9,871 reviews

Alaska Airlines

8.0

Very good

9,871 reviews

Reviews

1 / 20

4.0

Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >

Southwest

8.0

Very good

4,279 reviews

Alaska Airlines

8.0

Very good

9,871 reviews

Reviews

1 / 20

4.0

Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >

Delta

8.0

Very good

7,918 reviews

Alaska Airlines

8.0

Very good

9,871 reviews

Reviews

1 / 20

4.0

Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >

United Airlines

7.4

Good

8,658 reviews

Alaska Airlines

8.0

Very good

9,871 reviews

Reviews

1 / 20

4.0

Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >

American Airlines

7.2

Good

10,000 reviews

Alaska Airlines

8.0

Very good

9,871 reviews

Reviews

1 / 20

4.0

Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >

Related info for your journey

What are the cheapest airlines flying from San Antonio to Des Moines round-trip?
Currently priced at $284, Delta will fly you from San Antonio to Des Moines and back. In addition to Delta, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from American Airlines and United Airlines - these airlines can fly you to your destination from $289 and $303, respectively. Delta is priced at 36% lower than the current average price of a flight leaving 3 months from now.
What are the cheapest airlines to fly from San Antonio to Des Moines one-way?
$136 is the cheapest one-way deal found within the past few days, from American Airlines. You may also be able to find cheap deals on Delta and United Airlines, with prices starting from $152 and $263, respectively.
Can I find deals for flights from San Antonio to Des Moines that include hotel bookings?
Yes. In addition to deals on San Antonio to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from San Antonio to Des Moines?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Antonio to Des Moines.
Can I find deals for business class flights from San Antonio to Des Moines?
Yes. Cheapflights offers flight deals from San Antonio to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from San Antonio to Des Moines?
Currently, August is the cheapest month in which you can book a flight from San Antonio to Des Moines (average of $336). Flying from San Antonio to Des Moines in June is currently the most expensive (average of $422). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Ames

Altoona

Johnston

Boone

West Des Moines

Ankeny

Browse thousands of different options on Cheapflights for your next trip

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Other flights to Des Moines

Top 4 airlines flying from San Antonio to Des Moines

Airline	Cheapest	Average	Flexibility	On-time
Frontier	Cheapest$208	Average$364	FlexibilityNo cancel fee	On-time62%
Delta	Cheapest$247	Average$336	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$291	Average$415	FlexibilityNo cancel fee	On-time71%
United Airlines	Cheapest$369	Average$557	FlexibilityNo cancel fee	On-time69%

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$128+ Cheap flights from San Antonio to Des Moines (SAT - DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/1. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from San Antonio to Des Moines with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

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Cheap flight deals from San Antonio to Des Moines

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from San Antonio to Des Moines

Cheapest flights from San Antonio to Des MoinesExplore the most affordable flight options available from San Antonio to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 15, 2025.

Explore the most affordable flight options available from San Antonio to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 15, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from San Antonio to Des Moines that are best for you.

Compare providers for flights from San Antonio to Des Moines

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Antonio to Des Moines in April.

Best time to book a flight from San Antonio to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from San Antonio with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from San Antonio to Des Moines

What is the cheapest month to book a flight from San Antonio to Des Moines?

What is the cheapest time of day to fly from SAT to DSM?

Find hourly flight availability from San Antonio to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 15, 2025.

Rainfall in Des Moines by month

Plan your trip to Des Moines by taking into account the average rainfall totals by month.

Temperature in Des Moines by month

Plan your trip to Des Moines by taking into account the average temperature totals by month.

Reviews of airlines servicing Des Moines

To help decide which airline to fly from San Antonio to Des Moines, see what other customers have to say about Alaska Airlines, Southwest and Delta. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from San Antonio to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines flying from San Antonio to Des Moines round-trip?

What are the cheapest airlines to fly from San Antonio to Des Moines one-way?

Can I find deals for flights from San Antonio to Des Moines that include hotel bookings?

How can I find direct flights from San Antonio to Des Moines?

Can I find deals for business class flights from San Antonio to Des Moines?

What is the cheapest month to book a flight from San Antonio to Des Moines?

Traveling to a place near San Antonio?

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Alternative routes for San Antonio to Des Moines

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Top 4 airlines flying from San Antonio to Des Moines

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Cheapest flights from San Antonio to Des Moines
Explore the most affordable flight options available from San Antonio to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 15, 2025.