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Des Moines

$81+ Cheap flights from Ohio to Des Moines (DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/11. Fares are subject to change and may not be available on all flights or dates of travel.
CVG — DSM
Jan 14 — Jan 211
Wed 1/14
Wed 1/21
1 adult, Economy
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Cheap flight deals from Ohio to Des Moines

Cheapest flights from Ohio to Des Moines
Explore the most affordable flight options available from Ohio to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 15, 2025.

This Kiwi.com deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/265:30 amCLE - DSM
1 stop10h 28mMultiple Airlines
Thu 1/88:30 amDSM - CLE
2 stops15h 02mMultiple Airlines
Deal found 12/13$350
This Kiwi.com deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/247:00 amPIT - DSM
1 stop13h 40mMultiple Airlines
Sun 12/287:30 pmDSM - PIT
1 stop26h 12mMultiple Airlines
Deal found 12/14$440
This Delta deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/296:00 amCMH - DSM
1 stop5h 38mDelta
Fri 1/26:15 amDSM - CMH
1 stop4h 05mDelta
Deal found 12/13$447
This American Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/298:11 pmPIT - DSM
1 stop5h 26mAmerican Airlines
Fri 1/23:27 pmDSM - PIT
1 stop4h 33mAmerican Airlines
Deal found 12/14$447
This Delta deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/296:29 amCLE - DSM
1 stop4h 20mDelta
Fri 1/25:55 pmDSM - CLE
1 stop5h 00mDelta
Deal found 12/14$447
This United Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/292:19 pmCVG - DSM
1 stop4h 46mUnited Airlines
Fri 1/26:46 pmDSM - CVG
1 stop3h 58mUnited Airlines
Deal found 12/14$447
This Southwest deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/269:15 pmCLE - DSM
1 stop3h 50mSouthwest
Thu 1/86:10 amDSM - CLE
1 stop3h 35mSouthwest
Deal found 12/13$449
This American Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/296:00 amCLE - DSM
2 stops7h 54mAmerican Airlines
Fri 1/26:40 amDSM - CLE
1 stop7h 00mAmerican Airlines
Deal found 12/14$452
This American Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/288:04 amPIT - DSM
1 stop5h 22mAmerican Airlines
Thu 1/11:25 pmDSM - PIT
1 stop6h 35mAmerican Airlines
Deal found 12/13$490
This United Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/301:59 pmCAK - DSM
1 stop5h 06mUnited Airlines
Sat 1/36:46 pmDSM - CAK
1 stop24h 43mUnited Airlines
Deal found 12/14$493
This Delta deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/308:44 amDTW - DSM
Nonstop2h 05mDelta
Sat 1/36:15 amDSM - DTW
Nonstop1h 52mDelta
Deal found 12/14$499
This Delta deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/236:20 amPIT - DSM
1 stop4h 29mDelta
Sun 12/285:55 pmDSM - PIT
1 stop4h 41mDelta
Deal found 12/14$512

Find flight deals from Ohio to Des Moines

Keep the following information in mind while searching for Ohio to Des Moines flight deals. Data was last updated December 15, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$261
(Kiwi.com)

One-way from

$81
(Frontier)

Popular in

January

Cheapest in

November

Average price

$462
Provider with most accurate pricing for Cleveland Hopkins Intl-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Cleveland Hopkins Intl-Des Moines flights.
Search Deals
From Ohio to Des Moines
Search Deals
One-way flight from Ohio to Des Moines
Search Deals
Highest demand for flights based on searches. 29% potential increase in price ($170 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 7% potential price decrease ($29 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Ohio to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 15, 2025.
Use the filters below to find and compare flights from Ohio to Des Moines that are best for you.

Fly from

Ohio

Fly to

Des Moines

Route

Depart

Return

Price

CincinnatiDes Moines

CVG - DSM

CVGDSM

Cincinnati Cinci./N. Kentucky

Thu 2/19

1:07 pm-11:12 pm

2 stops11h 05m

Des Moines

Sat 2/21

6:14 pm-8:17 pm

1 stop25h 03m

$261

DaytonDes Moines

DAY - DSM

DAYDSM

Dayton

Thu 2/19

6:00 am-1:17 pm

2 stops8h 17m

Des Moines

Sat 2/21

2:02 pm-8:12 pm

1 stop5h 10m

$274

CincinnatiDes Moines

CVG - DSM

CVGDSM

Cincinnati Cinci./N. Kentucky

Sat 1/10

7:00 am-10:55 am

1 stop4h 55m

Des Moines

Sat 1/17

11:30 am-4:43 pm

1 stop4h 13m

$276

CincinnatiDes Moines

CVG - DSM

CVGDSM

Cincinnati Cinci./N. Kentucky

Sat 1/10

8:54 am-4:24 pm

2 stops8h 30m

Des Moines

Sat 1/17

11:42 am-11:45 pm

2 stops11h 03m

$286

ClevelandDes Moines

CLE - DSM

CLEDSM

Cleveland Hopkins Intl

Wed 1/7

3:52 pm-8:54 pm

1 stop6h 02m

Des Moines

Sat 1/10

12:25 pm-6:56 pm

1 stop5h 31m

$297

ClevelandDes Moines

CLE - DSM

CLEDSM

Cleveland Hopkins Intl

Wed 1/7

2:16 pm-5:47 pm

1 stop4h 31m

Des Moines

Sat 1/10

7:50 am-3:26 pm

1 stop6h 36m

$297

DetroitDes Moines

DTW - DSM

DTWDSM

Detroit Metropolitan Wayne County

Thu 1/15

11:00 am-10:46 pm

2 stops12h 46m

Des Moines

Sun 1/18

2:58 pm-11:59 pm

1 stop8h 01m

$298

ClevelandDes Moines

CLE - DSM

CLEDSM

Cleveland Hopkins Intl

Wed 1/7

4:13 pm-11:08 pm

2 stops7h 55m

Des Moines

Sat 1/10

4:00 pm-10:43 pm

1 stop5h 43m

$302

DetroitDes Moines

DTW - DSM

DTWDSM

Detroit Metropolitan Wayne County

Fri 1/9

10:43 am-9:21 pm

1 stop11h 38m

Des Moines

Sun 1/11

2:58 pm-10:05 am

1 stop18h 07m

$305

ColumbusDes Moines

CMH - DSM

CMHDSM

Columbus

Thu 1/1

5:53 pm-12:37 am

1 stop7h 44m

Des Moines

Sun 1/4

6:52 pm-2:30 am

1 stop6h 38m

$305

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/13

Showing 1-10 of 60 results
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Best time to book a flight from Ohio to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Ohio with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Ohio to Des Moines

What is the cheapest month to book a flight from Ohio to Des Moines?

Currently, April is the cheapest month in which you can book a flight from Ohio to Des Moines (average of $143). Flying from Ohio to Des Moines in January is currently the most expensive (average of $299). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from OH to DSM?

Find hourly flight availability from Ohio to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 15, 2025.

It’s typically best to fly out from Ohio to Des Moines in the evening. Doing so could potentially save you 25% on the flight price compared to flying at noon, which is usually more expensive.

What is the cheapest day to fly from Ohio to Des Moines?

Use this chart to determine the cheapest time to fly round-trip from Ohio to Des Moines. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Ohio to Des Moines flight should consider departing on Saturday evenings when fares are most often at their lowest. Monday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Related info for your journey

Find useful and relevant information for your journey from Ohio to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Des Moines from Ohio?

    If you book a flight to Des Moines from Ohio, you will be flying to Des Moines, which is the city’s only airport. Des Moines (DSM) is located 3.6 mi from the center of Des Moines.

  • How long is the flight from Ohio to Des Moines?

    There are many flights that can get you from Ohio to Des Moines in 4h 55m. Fly via American Airlines, United Airlines, or Delta to get the fastest option. The distance between Ohio and Des Moines is about 504 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Ohio to Des Moines one-way?

    To fly one-way, consider booking your trip with United Airlines, which is currently one of the cheapest options available, starting at $118. American Airlines flights start at $118 while deals on Delta start at $121 one-way.

  • What are the most popular routes from Ohio to Des Moines?

    While some choose either Cleveland Hopkins Intl - Des Moines or Pittsburgh - Des Moines, Detroit Metropolitan Wayne County - Des Moines is the most popular route from Ohio to Des Moines.

  • Can I find deals for flights from Ohio to Des Moines that include hotel bookings?

    Yes. In addition to deals on Ohio to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Ohio to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Ohio to Des Moines.

  • Can I find deals for business class flights from Ohio to Des Moines?

    Yes. Cheapflights offers flight deals from Ohio to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Ohio to Des Moines?

    Currently, April is the cheapest month in which you can book a flight from Ohio to Des Moines (average of $143). Flying from Ohio to Des Moines in January is currently the most expensive (average of $299). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Johnston
Boone
Ames
Clive
West Des Moines
Ankeny

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Alternative routes for Ohio to Des Moines

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Top 4 airlines flying from Ohio to Des Moines

Discover the top 4 airlines that operate flights from Ohio to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$163Average$362FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$236Average$372FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$243Average$373FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$286Average$391FlexibilityNo cancel feeOn-time63%

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