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Des Moines

$89+ Cheap flights from Missouri to Des Moines (DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/18. Fares are subject to change and may not be available on all flights or dates of travel.
STL — DSM
Jan 26 — Feb 21
Sun 1/26
Sun 2/2
1 adult, Economy
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Cheap flight deals from Missouri to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Missouri (USMO) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 21, 2025.

Round-trip from

$137
(Southwest)

One-way from

$89
(Delta)

Good round-trip deal

$400 or less

Good one-way deal

$326 or less
From Missouri to Des Moines
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One-way flight from Missouri to Des Moines
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Price to beat on a round-trip flight from Missouri to Des Moines.
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Price to beat on a one-way flight from Missouri to Des Moines.
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Find flight deals from Missouri to Des Moines

Cheapest flights from Missouri to Des Moines
Explore the most affordable flight options available from Missouri to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 21, 2025.

This Southwest deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/1310:25 pmSTL - DSM
Nonstop1h 10mSouthwest
Mon 2/175:30 amDSM - STL
Nonstop1h 20mSouthwest
Deal found 1/21$137
This Delta deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/1310:22 amSTL - DSM
1 stop6h 08mDelta
Mon 2/175:55 pmDSM - STL
1 stop4h 22mDelta
Deal found 1/21$177
This Southwest deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/127:00 amMCI - DSM
1 stop5h 20mSouthwest
Wed 2/198:30 amDSM - MCI
1 stop8h 10mSouthwest
Deal found 1/21$255
This United Airlines deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/51:02 pmSTL - DSM
1 stop4h 52mUnited Airlines
Sun 2/98:00 amDSM - STL
1 stop6h 37mUnited Airlines
Deal found 1/21$453
This Mytrip deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/134:00 pmSTL - DSM
3 stops31h 31mMultiple Airlines
Mon 2/171:34 pmDSM - STL
3 stops25h 08mMultiple Airlines
Deal found 1/21$476
This United Airlines deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/55:15 pmMCI - DSM
1 stop22h 56mUnited Airlines
Sun 2/95:15 pmDSM - MCI
1 stop27h 16mUnited Airlines
Deal found 1/21$619

Find flights from Missouri to Des Moines within your budget

Customize your flight search to find flights from Missouri to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2025.

Fly from

Any airport

Fly to

Any airport

Route

Depart

Return

Price

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Thu 2/13

10:25 pm-11:35 pm

Nonstop1h 10m

Des Moines

Mon 2/17

5:30 am-6:50 am

Nonstop1h 20m

$137

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Thu 2/13

10:22 am-4:30 pm

1 stop6h 08m

Des Moines

Mon 2/17

5:55 pm-10:17 pm

1 stop4h 22m

$177

Kansas CityDes Moines

MCI - DSM

MCIDSM

Kansas City

Wed 2/12

7:00 am-12:20 pm

1 stop5h 20m

Des Moines

Wed 2/19

8:30 am-4:40 pm

1 stop8h 10m

$255

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Wed 2/5

1:02 pm-5:54 pm

1 stop4h 52m

Des Moines

Sun 2/9

8:00 am-2:37 pm

1 stop6h 37m

$453

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Thu 2/13

4:00 pm-11:31 pm

3 stops31h 31m

Des Moines

Mon 2/17

1:34 pm-2:42 pm

3 stops25h 08m

$476

Kansas CityDes Moines

MCI - DSM

MCIDSM

Kansas City

Wed 2/5

5:15 pm-4:11 pm

1 stop22h 56m

Des Moines

Sun 2/9

5:15 pm-8:31 pm

1 stop27h 16m

$619

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Tue 2/18

6:00 am-10:40 am

1 stop4h 40m

$89

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Fri 2/14

9:35 am-10:45 am

Nonstop1h 10m

$166

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Wed 4/23

9:39 am-11:42 pm

2 stops14h 03m

$268

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Sun 2/2

4:28 pm-6:22 pm

3 stops25h 54m

$270

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/21

Showing 1-10 of 11 results
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Best time to book a flight from Missouri to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Missouri to Des Moines

Get recent, data-driven insights about flights from Missouri to Des Moines including ideal travel times, pricing trends, and more.

What is the cheapest time of day to fly from MO to DSM?

Find hourly flight availability from Missouri to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 21, 2025.

When flying from Missouri to Des Moines, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Des Moines by month

Plan your trip to Des Moines by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Des Moines ranges from 1.0 - 4.9 inches per month. June is typically the wettest month, when rainfall can reach 4.9 in. January is typically the driest time to visit Des Moines when rainfall is around 1.0 in.

Temperature in Des Moines by month

Plan your trip to Des Moines by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Des Moines, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 77.0 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 23.0 F).

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated January 21, 2025.
Read through reviews of airlines operating flights from Missouri to Des Moines, such as Southwest and United Airlines. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
4,662 reviews

Food

7.2

Comfort

8.1

Crew

8.7

Boarding

8.2

Entertainment

7.7

Overall

8.1

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Southwest
8.1
Very good
4,662 reviews
Southwest
8.1
Very good
4,662 reviews

Food

7.2

Comfort

8.1

Crew

8.7

Boarding

8.2

Entertainment

7.7

Overall

8.1

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Delta
8.0
Very good
8,521 reviews
Southwest
8.1
Very good
4,662 reviews

Food

7.2

Comfort

8.1

Crew

8.7

Boarding

8.2

Entertainment

7.7

Overall

8.1

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

United Airlines
7.4
Good
8,984 reviews
Southwest
8.1
Very good
4,662 reviews

Food

7.2

Comfort

8.1

Crew

8.7

Boarding

8.2

Entertainment

7.7

Overall

8.1

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

American Airlines
7.2
Good
10,000 reviews
Southwest
8.1
Very good
4,662 reviews

Food

7.2

Comfort

8.1

Crew

8.7

Boarding

8.2

Entertainment

7.7

Overall

8.1

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Des Moines from Missouri?

    If you book a flight to Des Moines from Missouri, you will be flying to Des Moines, which is the city’s only airport. Des Moines (DSM) is located 3.6 mi from the center of Des Moines.

  • What are the cheapest airlines to fly from Missouri to Des Moines one-way?

    To fly one-way, consider booking your trip with Delta, which is currently one of the cheapest options available, starting at $89. Southwest flights start at $166 while deals on United Airlines start at $268 one-way.

  • What are the cheapest flights from Missouri to Des Moines?

    Looking for the cheapest flight from Missouri to Des Moines? While on average our users pay $405, our data indicates the cheapest price to be $154. The most popular route (Lambert-St Louis - Des Moines), is priced around $285.

  • Can I find deals for flights from Missouri to Des Moines that include hotel bookings?

    Yes. In addition to deals on Missouri to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Des Moines.

  • Can I find deals for business class flights from Missouri to Des Moines?

    Yes. Cheapflights offers flight deals from Missouri to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Des Moines?

    Currently, August is the cheapest month in which you can book a flight from Missouri to Des Moines (average of $336). Flying from Missouri to Des Moines in June is currently the most expensive (average of $422). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Missouri?

Book flights to Missouri if you plan to visit one of these locations
Ames
Altoona
Johnston
Boone
West Des Moines

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Alternative routes for Missouri to Des Moines

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Missouri to Des Moines

Discover the top 2 airlines that operate flights from Missouri to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2025.
AirlineCheapestAverageFlexibilityOn-time
SouthwestCheapest$229Average$363FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$232Average$388FlexibilityNo cancel feeOn-time71%
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