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$96+ Cheap flights from Mississippi to Des Moines (DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/24. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — DSM
Mar 13 — Mar 201
Thu 3/13
Thu 3/20
1 adult, Economy
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Cheap flight deals from Mississippi to Des Moines

Keep the following information in mind while searching for Mississippi to Des Moines flight deals. Data was last updated March 8, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$247
(Delta)

One-way from

$96
(Booking.com)

Popular in

March

Cheapest in

January

Average price

$691
Provider with most accurate pricing for Jackson-Evers Intl-Des Moines flight deals.
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Provider most trusted by Cheapflights users for Jackson-Evers Intl-Des Moines flights.
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From Mississippi to Des Moines
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One-way flight from Mississippi to Des Moines
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Highest demand for flights based on searches. 6% potential increase in price ($31 potential increase over avg. RT price).
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Cheapest flight prices on average. 6% potential price decrease ($26 potential savings vs. average RT price).
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Average for round-trip flights in March 2025
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Find flight deals from Mississippi to Des Moines

Cheapest flights from Mississippi to Des Moines
Explore the most affordable flight options available from Mississippi to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 8, 2025.

This Delta deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/304:42 pmMEM - DSM
1 stop5h 56mDelta
Wed 5/76:35 pmDSM - MEM
1 stop4h 41mDelta
Deal found 3/6$247
This Delta deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/271:06 pmGPT - DSM
1 stop4h 39mDelta
Sun 3/305:45 amDSM - GPT
1 stop6h 36mDelta
Deal found 3/5$249
This American Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/32:40 pmMEM - DSM
2 stops7h 37mAmerican Airlines
Sat 5/1011:53 amDSM - MEM
1 stop5h 11mAmerican Airlines
Deal found 3/6$252
This United Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/34:55 pmGPT - DSM
1 stop5h 50mUnited Airlines
Thu 4/108:00 amDSM - GPT
1 stop5h 26mUnited Airlines
Deal found 3/6$279
This American Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/312:48 pmGPT - DSM
2 stops11h 03mAmerican Airlines
Thu 4/1012:49 pmDSM - GPT
1 stop6h 22mAmerican Airlines
Deal found 3/6$284
This Southwest deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/38:25 amMEM - DSM
2 stops7h 25mSouthwest
Sat 5/108:30 amDSM - MEM
2 stops10h 35mSouthwest
Deal found 3/6$293
This Mytrip deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/36:48 pmGPT - DSM
2 stops28h 20mMultiple Airlines
Thu 4/107:30 amDSM - GPT
3 stops25h 15mMultiple Airlines
Deal found 3/6$425
This American Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/136:26 pmBTR - DSM
1 stop5h 23mAmerican Airlines
Sat 7/195:00 amDSM - BTR
1 stop6h 32mAmerican Airlines
Deal found 3/7$488
This United Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/1312:06 pmBTR - DSM
2 stops10h 40mUnited Airlines
Sat 7/1911:23 amDSM - BTR
2 stops11h 36mUnited Airlines
Deal found 3/7$554
This United Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/216:15 pmMEM - DSM
1 stop27h 23mUnited Airlines
Tue 3/251:41 pmDSM - MEM
1 stop7h 44mUnited Airlines
Deal found 3/6$838
This United Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/228:50 amMEI - DSM
1 stop13h 40mUnited Airlines
Wed 3/267:45 amDSM - MEI
1 stop5h 15mUnited Airlines
Deal found 3/6$1,045

Find flights from Mississippi to Des Moines within your budget

Customize your flight search to find flights from Mississippi to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 8, 2025.

Fly from

Mississippi

Fly to

Des Moines

Route

Depart

Return

Price

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

Wed 4/30

4:42 pm-10:38 pm

1 stop5h 56m

Des Moines

Wed 5/7

6:35 pm-11:16 pm

1 stop4h 41m

$247

GulfportDes Moines

GPT - DSM

GPTDSM

Gulfport Biloxi Regional

Thu 3/27

1:06 pm-5:45 pm

1 stop4h 39m

Des Moines

Sun 3/30

5:45 am-12:21 pm

1 stop6h 36m

$249

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

Sat 5/3

2:40 pm-10:17 pm

2 stops7h 37m

Des Moines

Sat 5/10

11:53 am-5:04 pm

1 stop5h 11m

$252

GulfportDes Moines

GPT - DSM

GPTDSM

Gulfport Biloxi Regional

Thu 4/3

4:55 pm-10:45 pm

1 stop5h 50m

Des Moines

Thu 4/10

8:00 am-1:26 pm

1 stop5h 26m

$279

GulfportDes Moines

GPT - DSM

GPTDSM

Gulfport Biloxi Regional

Thu 4/3

12:48 pm-11:51 pm

2 stops11h 03m

Des Moines

Thu 4/10

12:49 pm-7:11 pm

1 stop6h 22m

$284

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

Sat 5/3

8:25 am-3:50 pm

2 stops7h 25m

Des Moines

Sat 5/10

8:30 am-7:05 pm

2 stops10h 35m

$293

GulfportDes Moines

GPT - DSM

GPTDSM

Gulfport Biloxi Regional

Thu 4/3

6:48 pm-11:08 pm

2 stops28h 20m

Des Moines

Thu 4/10

7:30 am-8:45 am

3 stops25h 15m

$425

Baton RougeDes Moines

BTR - DSM

BTRDSM

Baton Rouge Ryan

Sun 7/13

6:26 pm-11:49 pm

1 stop5h 23m

Des Moines

Sat 7/19

5:00 am-11:32 am

1 stop6h 32m

$488

Baton RougeDes Moines

BTR - DSM

BTRDSM

Baton Rouge Ryan

Sun 7/13

12:06 pm-10:46 pm

2 stops10h 40m

Des Moines

Sat 7/19

11:23 am-10:59 pm

2 stops11h 36m

$554

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

Fri 3/21

6:15 pm-9:38 pm

1 stop27h 23m

Des Moines

Tue 3/25

1:41 pm-9:25 pm

1 stop7h 44m

$838

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/5

Showing 1-10 of 15 results
1
2

Best time to book a flight from Mississippi to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Mississippi to Des Moines

Get recent, data-driven insights about flights from Mississippi to Des Moines including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Mississippi to Des Moines?

Currently, August is the cheapest month in which you can book a flight from Mississippi to Des Moines (average of $336). Flying from Mississippi to Des Moines in June is currently the most expensive (average of $422). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MS to DSM?

Find hourly flight availability from Mississippi to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 8, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Mississippi to Des Moines as you normally would.

Rainfall in Des Moines by month

Plan your trip to Des Moines by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Des Moines ranges from 1.0 - 4.9 inches per month. June is typically the wettest month, when rainfall can reach 4.9 in. January is typically the driest time to visit Des Moines when rainfall is around 1.0 in.

Temperature in Des Moines by month

Plan your trip to Des Moines by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Des Moines, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 77.0 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 23.0 F).

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated March 8, 2025.
Get a feel of what it's like to fly with Southwest, Delta and United Airlines from Mississippi to Des Moines by reading reviews from past customers. In addition to providing an overall rating, users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
4,314 reviews

Entertainment

7.6

Food

7.1

Overall

8.1

Boarding

8.2

Crew

8.7

Comfort

8.1

Reviews

1 / 20

8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.

Southwest
8.1
Very good
4,314 reviews
Southwest
8.1
Very good
4,314 reviews

Entertainment

7.6

Food

7.1

Overall

8.1

Boarding

8.2

Crew

8.7

Comfort

8.1

Reviews

1 / 20

8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.

Delta
8.0
Very good
8,024 reviews
Southwest
8.1
Very good
4,314 reviews

Entertainment

7.6

Food

7.1

Overall

8.1

Boarding

8.2

Crew

8.7

Comfort

8.1

Reviews

1 / 20

8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.

United Airlines
7.4
Good
8,649 reviews
Southwest
8.1
Very good
4,314 reviews

Entertainment

7.6

Food

7.1

Overall

8.1

Boarding

8.2

Crew

8.7

Comfort

8.1

Reviews

1 / 20

8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.

American Airlines
7.2
Good
10,000 reviews
Southwest
8.1
Very good
4,314 reviews

Entertainment

7.6

Food

7.1

Overall

8.1

Boarding

8.2

Crew

8.7

Comfort

8.1

Reviews

1 / 20

8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.

Frontier
6.0
Okay
3,314 reviews
Southwest
8.1
Very good
4,314 reviews

Entertainment

7.6

Food

7.1

Overall

8.1

Boarding

8.2

Crew

8.7

Comfort

8.1

Reviews

1 / 20

8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.

Related info for your journey

Find useful and relevant information for your journey from Mississippi to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Des Moines from Mississippi?

    Des Moines (DSM) is the airport you will fly into if you book a flight from Mississippi to Des Moines. It is only a 3.6 mi journey from Des Moines (DSM) to Des Moines’s city center.

  • What are the cheapest airlines to fly from Mississippi to Des Moines one-way?

    The cheapest airline one-way is Frontier, with whom users have recently found tickets for as low as $96. However, be on the lookout for offers from Delta and Southwest, as they are both options that can get you from Mississippi to Des Moines for a low price.

  • What are the most popular routes from Mississippi to Des Moines?

    The most popular flight routes from Mississippi to Des Moines are Baton Rouge Ryan - Des Moines, Memphis - Des Moines and Gulfport Biloxi Regional - Des Moines.

  • Can I find deals for flights from Mississippi to Des Moines that include hotel bookings?

    Yes. In addition to deals on Mississippi to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to Des Moines.

  • Can I find deals for business class flights from Mississippi to Des Moines?

    Yes. Cheapflights offers flight deals from Mississippi to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mississippi to Des Moines?

    Currently, August is the cheapest month in which you can book a flight from Mississippi to Des Moines (average of $336). Flying from Mississippi to Des Moines in June is currently the most expensive (average of $422). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Mississippi?

Book flights to Mississippi if you plan to visit one of these locations
Ames
Altoona
Johnston
Boone
West Des Moines

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Alternative routes for Mississippi to Des Moines

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Mississippi to Des Moines

Discover the top 2 airlines that operate flights from Mississippi to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 8, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$205Average$340FlexibilityNo cancel feeOn-time71%
DeltaCheapest$256Average$449FlexibilityNo cancel feeOn-timeN/A
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