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Des Moines

$75+ Cheap flights from Mesa, AZ to Des Moines (DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/17. Fares are subject to change and may not be available on all flights or dates of travel.
PHX — DSM
Feb 28 — Mar 71
Fri 2/28
Fri 3/7
1 adult, Economy
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The best prices from Mesa to Des Moines are usually found in October or February, booked 85 days in advance, depart on a Saturday or Wednesday and return on a Tuesday

Cheap flight deals from Mesa to Des Moines

Keep the following information in mind while searching for Mesa to Des Moines flight deals. Data was last updated February 23, 2025.

Round-trip from

$160
(Frontier)

One-way from

$75
(Frontier)

Popular in

January

Cheapest in

October

Average price

$317
From Mesa to Des Moines
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One-way flight from Mesa to Des Moines
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Highest demand for flights based on searches. 4% potential increase in price ($19 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($12 potential savings vs. average RT price).
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Average for round-trip flights in February 2025
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Find flight deals from Mesa to Des Moines

Cheapest flights from Mesa to Des Moines
Explore the most affordable flight options available from Mesa to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 23, 2025.

This Frontier deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/176:00 amPHX - DSM
1 stop11h 17mFrontier
Mon 3/248:17 pmDSM - PHX
1 stop5h 42mFrontier
Deal found 2/21$150
This Southwest deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/210:00 amPHX - DSM
Nonstop2h 40mSouthwest
Mon 4/74:55 pmDSM - PHX
Nonstop3h 10mSouthwest
Deal found 2/20$222
This American Airlines deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/241:04 amPHX - DSM
1 stop8h 17mAmerican Airlines
Mon 4/286:20 pmDSM - PHX
Nonstop3h 17mAmerican Airlines
Deal found 2/21$257
This United Airlines deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2412:45 amPHX - DSM
1 stop7h 55mUnited Airlines
Mon 4/285:10 pmDSM - PHX
1 stop6h 24mUnited Airlines
Deal found 2/21$267
This Delta deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/3010:59 pmPHX - DSM
1 stop8h 38mDelta
Sat 5/37:00 amDSM - PHX
1 stop7h 47mDelta
Deal found 2/22$272
This Mytrip deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/73:38 pmPHX - DSM
1 stop5h 29mMultiple Airlines
Mon 3/101:32 pmDSM - PHX
3 stops30h 35mMultiple Airlines
Deal found 2/21$328

Find flights from Mesa to Des Moines within your budget

Customize your flight search to find flights from Mesa to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 23, 2025.

Fly from

Mesa

Fly to

Des Moines

Route

Depart

Return

Price

PhoenixDes Moines

PHX - DSM

PHXDSM

Phoenix Sky Harbor Intl

Mon 3/17

6:00 am-7:17 pm

1 stop11h 17m

Des Moines

Mon 3/24

8:17 pm-11:59 pm

1 stop5h 42m

$150

PhoenixDes Moines

PHX - DSM

PHXDSM

Phoenix Sky Harbor Intl

Wed 4/2

10:00 am-2:40 pm

Nonstop2h 40m

Des Moines

Mon 4/7

4:55 pm-6:05 pm

Nonstop3h 10m

$222

PhoenixDes Moines

PHX - DSM

PHXDSM

Phoenix Sky Harbor Intl

Thu 4/24

1:04 am-11:21 am

1 stop8h 17m

Des Moines

Mon 4/28

6:20 pm-7:37 pm

Nonstop3h 17m

$257

PhoenixDes Moines

PHX - DSM

PHXDSM

Phoenix Sky Harbor Intl

Thu 4/24

12:45 am-10:40 am

1 stop7h 55m

Des Moines

Mon 4/28

5:10 pm-9:34 pm

1 stop6h 24m

$267

PhoenixDes Moines

PHX - DSM

PHXDSM

Phoenix Sky Harbor Intl

Wed 4/30

10:59 pm-9:37 am

1 stop8h 38m

Des Moines

Sat 5/3

7:00 am-12:47 pm

1 stop7h 47m

$272

PhoenixDes Moines

PHX - DSM

PHXDSM

Phoenix Sky Harbor Intl

Fri 3/7

3:38 pm-10:07 pm

1 stop5h 29m

Des Moines

Mon 3/10

1:32 pm-6:07 pm

3 stops30h 35m

$328

PhoenixDes Moines

PHX - DSM

PHXDSM

Phoenix Sky Harbor Intl

Mon 3/17

11:08 am-7:17 pm

1 stop6h 09m

$75

PhoenixDes Moines

PHX - DSM

PHXDSM

Phoenix Sky Harbor Intl

Mon 5/12

8:35 am-1:20 pm

Nonstop2h 45m

$104

PhoenixDes Moines

PHX - DSM

PHXDSM

Phoenix Sky Harbor Intl

Mon 5/12

11:59 pm-10:30 am

1 stop8h 31m

$114

PhoenixDes Moines

PHX - DSM

PHXDSM

Phoenix Sky Harbor Intl

Tue 5/13

10:55 pm-9:19 am

1 stop8h 24m

$119

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/21

Showing 1-10 of 13 results
1
2

Best time to book a flight from Mesa to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Mesa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Mesa to Des Moines

Get recent, data-driven insights about flights from Mesa to Des Moines including ideal travel times, pricing trends, and more.

How far ahead should I book a flight from Mesa to Des Moines?

Use this chart to determine the optimal time to book a round-trip flight from Mesa to Des Moines. Price data was last updated on February 14, 2025.

The price you pay for your flight from Mesa to Des Moines may vary depending on when you book. For the best chance of a lower fare, look to book 85 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Mesa to Des Moines?

Currently, August is the cheapest month in which you can book a flight from Mesa to Des Moines (average of $336). Flying from Mesa to Des Moines in June is currently the most expensive (average of $422). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MS9 to DSM?

Find hourly flight availability from Mesa to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 23, 2025.

When flying from Mesa to Des Moines, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

What is the cheapest day to fly from Mesa to Des Moines?

Use this chart to determine the cheapest time to fly round-trip from Mesa to Des Moines. Price data was last updated on February 16, 2025.

Travelers seeking maximum savings on their Mesa to Des Moines flight should consider departing on Wednesday evenings when fares are most often at their lowest. Wednesday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Mesa to Des Moines

Explore weekly flight availability from Mesa to Des Moines. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated February 23, 2025.

The most flights from MS9 to DSM are scheduled on a Thursday (8 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (3 on average).

Rainfall in Des Moines by month

Plan your trip to Des Moines by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Des Moines ranges from 1.0 - 4.9 inches per month. June is typically the wettest month, when rainfall can reach 4.9 in. January is typically the driest time to visit Des Moines when rainfall is around 1.0 in.

Temperature in Des Moines by month

Plan your trip to Des Moines by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Des Moines, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 77.0 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 23.0 F).

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated February 23, 2025.
Read through reviews of airlines operating flights from Mesa to Des Moines, such as Southwest, Delta and United Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
4,396 reviews

Entertainment

7.6

Comfort

8.1

Food

7.1

Boarding

8.2

Crew

8.7

Overall

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Southwest
8.1
Very good
4,396 reviews
Southwest
8.1
Very good
4,396 reviews

Entertainment

7.6

Comfort

8.1

Food

7.1

Boarding

8.2

Crew

8.7

Overall

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Delta
8.0
Very good
8,203 reviews
Southwest
8.1
Very good
4,396 reviews

Entertainment

7.6

Comfort

8.1

Food

7.1

Boarding

8.2

Crew

8.7

Overall

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

United Airlines
7.4
Good
8,754 reviews
Southwest
8.1
Very good
4,396 reviews

Entertainment

7.6

Comfort

8.1

Food

7.1

Boarding

8.2

Crew

8.7

Overall

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Allegiant Air
7.3
Good
764 reviews
Southwest
8.1
Very good
4,396 reviews

Entertainment

7.6

Comfort

8.1

Food

7.1

Boarding

8.2

Crew

8.7

Overall

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

American Airlines
7.2
Good
10,000 reviews
Southwest
8.1
Very good
4,396 reviews

Entertainment

7.6

Comfort

8.1

Food

7.1

Boarding

8.2

Crew

8.7

Overall

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Related info for your journey

Find useful and relevant information for your journey from Mesa to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Des Moines from Mesa?

    For a flight from Mesa to Des Moines, you will be flying into Des Moines. Des Moines (DSM) is just 3.6 mi from the center of the city. Des Moines is the only Des Moines airport and it handles 6 inbound flights from Mesa per day. 6 airlines have flights to Des Moines from Mesa on a regular basis.

  • What are the cheapest airlines to fly from Mesa to Des Moines one-way?

    One-way options have recently been found by users for as low as $75 on Frontier. Other airlines that offer cheap prices include American Airlines from $104 and United Airlines from $114 one-way.

  • What are the most reliable airlines from Mesa to Des Moines?

    Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Mesa to Des Moines on time: American Airlines (95%), Alaska Airlines (95%), Envoy Air (95%).

  • What are the cheapest flights from Mesa to Des Moines?

    While on average a flight from Mesa to Des Moines is generally $284, our data shows the cheapest flight currently is $99. When looking at the most popular route, (Phoenix Sky Harbor Intl - Des Moines), you can expect to pay $204 for that flight.

  • Can I find deals for flights from Mesa to Des Moines that include hotel bookings?

    Yes. In addition to deals on Mesa to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mesa to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mesa to Des Moines.

  • Can I find deals for business class flights from Mesa to Des Moines?

    Yes. Cheapflights offers flight deals from Mesa to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mesa to Des Moines?

    Currently, August is the cheapest month in which you can book a flight from Mesa to Des Moines (average of $336). Flying from Mesa to Des Moines in June is currently the most expensive (average of $422). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Mesa?

Book flights to Mesa if you plan to visit one of these locations
Ames
Altoona
Johnston
Boone
West Des Moines

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Top 6 airlines flying from Mesa to Des Moines

Discover the top 6 airlines that operate flights from Mesa to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 23, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$100Average$201FlexibilityNo cancel feeOn-time88%
FrontierCheapest$104Average$171FlexibilityNo cancel feeOn-time62%
DeltaCheapest$216Average$318FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$216Average$568FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$218Average$359FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$219Average$379FlexibilityNo cancel feeOn-time71%
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