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Des Moines

$81+ Cheap flights from Key Largo, FL to Des Moines (DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/19. Fares are subject to change and may not be available on all flights or dates of travel.
MIA — DSM
Feb 27 — Mar 61
Thu 2/27
Thu 3/6
1 adult, Economy
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Cheap flight deals from Key Largo to Des Moines

Keep the following information in mind while searching for Key Largo to Des Moines flight deals. Data was last updated February 22, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$257
(Delta)

One-way from

$81
(Frontier)

Popular in

June

Cheapest in

November

Average price

$492
Provider with most accurate pricing for Miami-Des Moines flight deals.
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Provider most trusted by Cheapflights users for Miami-Des Moines flights.
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From Key Largo to Des Moines
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One-way flight from Key Largo to Des Moines
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Highest demand for flights based on searches. 7% potential increase in price ($33 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($13 potential savings vs. average RT price).
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Average for round-trip flights in February 2025
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Find flight deals from Key Largo to Des Moines

Cheapest flights from Key Largo to Des Moines
Explore the most affordable flight options available from Key Largo to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 22, 2025.

This Delta deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1212:40 pmMIA - DSM
1 stop5h 39mDelta
Wed 3/196:30 pmDSM - MIA
1 stop5h 15mDelta
Deal found 2/21$257
This Mytrip deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/152:56 pmMIA - DSM
1 stop29h 49mFrontier
Sun 3/238:35 pmDSM - MIA
1 stop7h 41mFrontier
Deal found 2/20$258
This Mytrip deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/129:28 amMIA - DSM
2 stops38h 13mMultiple Airlines
Wed 3/196:23 pmDSM - MIA
2 stops20h 11mMultiple Airlines
Deal found 2/21$275
This United Airlines deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/228:00 amMIA - DSM
1 stop9h 29mUnited Airlines
Tue 7/296:20 amDSM - MIA
2 stops12h 12mUnited Airlines
Deal found 2/22$342
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/156:30 amMIA - DSM
1 stop8h 22mAmerican Airlines
Sun 3/236:00 amDSM - MIA
Nonstop3h 19mAmerican Airlines
Deal found 2/20$350
This Southwest deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/262:50 pmMIA - DSM
1 stop7h 40mSouthwest
Sun 4/277:35 amDSM - MIA
1 stop7h 50mSouthwest
Deal found 2/22$360

Find flights from Key Largo to Des Moines within your budget

Customize your flight search to find flights from Key Largo to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 22, 2025.

Fly from

Key Largo

Fly to

Des Moines

Route

Depart

Return

Price

MiamiDes Moines

MIA - DSM

MIADSM

Miami

Wed 3/12

12:40 pm-5:19 pm

1 stop5h 39m

Des Moines

Wed 3/19

6:30 pm-12:45 am

1 stop5h 15m

$257

MiamiDes Moines

MIA - DSM

MIADSM

Miami

Sat 3/15

2:56 pm-7:45 pm

1 stop29h 49m

Des Moines

Sun 3/23

8:35 pm-5:16 am

1 stop7h 41m

$258

MiamiDes Moines

MIA - DSM

MIADSM

Miami

Wed 3/12

9:28 am-10:41 pm

2 stops38h 13m

Des Moines

Wed 3/19

6:23 pm-3:34 pm

2 stops20h 11m

$275

MiamiDes Moines

MIA - DSM

MIADSM

Miami

Tue 7/22

8:00 am-4:29 pm

1 stop9h 29m

Des Moines

Tue 7/29

6:20 am-7:32 pm

2 stops12h 12m

$342

MiamiDes Moines

MIA - DSM

MIADSM

Miami

Sat 3/15

6:30 am-1:52 pm

1 stop8h 22m

Des Moines

Sun 3/23

6:00 am-10:19 am

Nonstop3h 19m

$350

MiamiDes Moines

MIA - DSM

MIADSM

Miami

Sat 4/26

2:50 pm-9:30 pm

1 stop7h 40m

Des Moines

Sun 4/27

7:35 am-4:25 pm

1 stop7h 50m

$360

MiamiDes Moines

MIA - DSM

MIADSM

Miami

Wed 3/19

6:25 am-7:17 pm

1 stop13h 52m

$81

MiamiDes Moines

MIA - DSM

MIADSM

Miami

Tue 3/18

6:00 am-10:40 am

1 stop5h 40m

$129

MiamiDes Moines

MIA - DSM

MIADSM

Miami

Wed 5/21

12:45 pm-10:05 pm

2 stops10h 20m

$134

MiamiDes Moines

MIA - DSM

MIADSM

Miami

Fri 3/28

7:40 pm-10:34 pm

Nonstop3h 54m

$144

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/21

Showing 1-10 of 12 results
1
2

Best time to book a flight from Key Largo to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Key Largo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Key Largo to Des Moines

Get recent, data-driven insights about flights from Key Largo to Des Moines including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Key Largo to Des Moines?

Currently, August is the cheapest month in which you can book a flight from Key Largo to Des Moines (average of $336). Flying from Key Largo to Des Moines in June is currently the most expensive (average of $422). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from KE9 to DSM?

Find hourly flight availability from Key Largo to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 22, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Key Largo to Des Moines as you normally would.

Weekly flight availability from Key Largo to Des Moines

Explore weekly flight availability from Key Largo to Des Moines. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated February 22, 2025.

The most flights from KE9 to DSM are scheduled on a Monday (2 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (2 on average).

Rainfall in Des Moines by month

Plan your trip to Des Moines by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Des Moines ranges from 1.0 - 4.9 inches per month. June is typically the wettest month, when rainfall can reach 4.9 in. January is typically the driest time to visit Des Moines when rainfall is around 1.0 in.

Temperature in Des Moines by month

Plan your trip to Des Moines by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Des Moines, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 77.0 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 23.0 F).

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated February 22, 2025.
Get a feel of what it's like to fly with Southwest, Delta and United Airlines from Key Largo to Des Moines by reading reviews from past customers. In addition to providing an overall rating, users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
4,395 reviews

Boarding

8.2

Crew

8.7

Comfort

8.1

Entertainment

7.6

Food

7.1

Overall

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Southwest
8.1
Very good
4,395 reviews
Southwest
8.1
Very good
4,395 reviews

Boarding

8.2

Crew

8.7

Comfort

8.1

Entertainment

7.6

Food

7.1

Overall

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Delta
8.0
Very good
8,203 reviews
Southwest
8.1
Very good
4,395 reviews

Boarding

8.2

Crew

8.7

Comfort

8.1

Entertainment

7.6

Food

7.1

Overall

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

United Airlines
7.4
Good
8,754 reviews
Southwest
8.1
Very good
4,395 reviews

Boarding

8.2

Crew

8.7

Comfort

8.1

Entertainment

7.6

Food

7.1

Overall

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

American Airlines
7.2
Good
10,000 reviews
Southwest
8.1
Very good
4,395 reviews

Boarding

8.2

Crew

8.7

Comfort

8.1

Entertainment

7.6

Food

7.1

Overall

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Frontier
6.0
Okay
3,352 reviews
Southwest
8.1
Very good
4,395 reviews

Boarding

8.2

Crew

8.7

Comfort

8.1

Entertainment

7.6

Food

7.1

Overall

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Related info for your journey

Find useful and relevant information for your journey from Key Largo to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Des Moines from Key Largo?

    Des Moines (DSM), located 3.6 mi from the city center, is the airport you fly into when you book flights from Key Largo to Des Moines. 3 airlines have flights to Des Moines from Key Largo on a regular basis. Booking flights from Key Largo to Des Moines should not be difficult; the airport handles an average of 2 inbound flights from Key Largo per day.

  • What are the cheapest airlines to fly from Key Largo to Des Moines one-way?

    The cheapest airlines for a one-way flight from Key Largo to Des Moines are Frontier ($81), Delta ($129), and Southwest ($134).

  • What are the most reliable airlines from Key Largo to Des Moines?

    Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Key Largo to Des Moines on time: American Airlines (77%), Qatar Airways (77%), Envoy Air (77%).

  • Can I find deals for flights from Key Largo to Des Moines that include hotel bookings?

    Yes. In addition to deals on Key Largo to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Key Largo to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Key Largo to Des Moines.

  • Can I find deals for business class flights from Key Largo to Des Moines?

    Yes. Cheapflights offers flight deals from Key Largo to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Key Largo to Des Moines?

    Currently, August is the cheapest month in which you can book a flight from Key Largo to Des Moines (average of $336). Flying from Key Largo to Des Moines in June is currently the most expensive (average of $422). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Key Largo?

Book flights to Key Largo if you plan to visit one of these locations
Ames
Altoona
Johnston
Boone
West Des Moines

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Top 3 airlines flying from Key Largo to Des Moines

Discover the top 3 airlines that operate flights from Key Largo to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 22, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$124Average$158FlexibilityNo cancel feeOn-time88%
DeltaCheapest$125Average$373FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$276Average$418FlexibilityNo cancel feeOn-time71%
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