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Des Moines

$95+ Cheap flights from Key Largo, FL to Des Moines (DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/7. Fares are subject to change and may not be available on all flights or dates of travel.
MIA — DSM
Apr 22 — Apr 291
Tue 4/22
Tue 4/29
1 adult, Economy
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Cheap flight deals from Key Largo to Des Moines

Keep the following information in mind while searching for Key Largo to Des Moines flight deals. Data was last updated April 17, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$247
(Delta)

One-way from

$95
(Frontier)

Popular in

April

Cheapest in

November

Average price

$486
Provider with most accurate pricing for Miami-Des Moines flight deals.
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Provider most trusted by Cheapflights users for Miami-Des Moines flights.
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From Key Largo to Des Moines
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One-way flight from Key Largo to Des Moines
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High demand for flights, 3% potential price rise
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Cheapest flight prices on average. 1% potential price decrease ($8 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from Key Largo to Des Moines

Cheapest flights from Key Largo to Des Moines
Explore the most affordable flight options available from Key Largo to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 17, 2025.

This Mytrip deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2912:28 pmMIA - DSM
1 stop11h 59mMultiple Airlines
Sun 6/17:15 pmDSM - MIA
2 stops23h 57mMultiple Airlines
Deal found 4/16$199
This Frontier deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/26:00 amMIA - DSM
1 stop13h 30mFrontier
Wed 5/77:30 pmDSM - MIA
1 stop8h 52mFrontier
Deal found 4/16$208
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2812:05 pmMIA - DSM
1 stop6h 45mDelta
Sat 5/316:35 pmDSM - MIA
1 stop5h 02mDelta
Deal found 4/16$247
This American Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/15:18 amMIA - DSM
1 stop7h 44mAmerican Airlines
Mon 5/511:53 amDSM - MIA
1 stop6h 32mAmerican Airlines
Deal found 4/16$349
This Southwest deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/223:15 pmMIA - DSM
2 stops7h 35mSouthwest
Sat 11/13:50 pmDSM - MIA
1 stop4h 45mSouthwest
Deal found 4/16$364
This United Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/251:21 pmMIA - DSM
2 stops9h 01mUnited Airlines
Mon 6/306:24 amDSM - MIA
1 stop7h 46mUnited Airlines
Deal found 4/17$461

Cheapflights Fare Finder

Customize your flight search to find flights from Key Largo to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
Use the filters below to find and compare flights from Key Largo to Des Moines that are best for you.

Fly from

Key Largo

Fly to

Des Moines

Route

Depart

Return

Price

MiamiDes Moines

MIA - DSM

MIADSM

Miami

Thu 5/29

12:28 pm-11:27 pm

1 stop11h 59m

Des Moines

Sun 6/1

7:15 pm-8:12 pm

2 stops23h 57m

$199

MiamiDes Moines

MIA - DSM

MIADSM

Miami

Fri 5/2

6:00 am-6:30 pm

1 stop13h 30m

Des Moines

Wed 5/7

7:30 pm-5:22 am

1 stop8h 52m

$208

MiamiDes Moines

MIA - DSM

MIADSM

Miami

Wed 5/28

12:05 pm-5:50 pm

1 stop6h 45m

Des Moines

Sat 5/31

6:35 pm-12:37 am

1 stop5h 02m

$247

MiamiDes Moines

MIA - DSM

MIADSM

Miami

Thu 5/1

5:18 am-12:02 pm

1 stop7h 44m

Des Moines

Mon 5/5

11:53 am-7:25 pm

1 stop6h 32m

$349

MiamiDes Moines

MIA - DSM

MIADSM

Miami

Sat 5/3

9:40 am-9:30 pm

2 stops12h 50m

Des Moines

Tue 5/6

6:40 am-8:55 pm

2 stops13h 15m

$400

MiamiDes Moines

MIA - DSM

MIADSM

Miami

Wed 6/25

1:21 pm-9:22 pm

2 stops9h 01m

Des Moines

Mon 6/30

6:24 am-3:10 pm

1 stop7h 46m

$461

MiamiDes Moines

MIA - DSM

MIADSM

Miami

Wed 7/16

6:50 am-1:00 pm

1 stop7h 10m

$119

MiamiDes Moines

MIA - DSM

MIADSM

Miami

Thu 5/1

7:22 am-6:54 pm

1 stop12h 32m

$121

MiamiDes Moines

MIA - DSM

MIADSM

Miami

Mon 5/19

6:00 am-6:30 pm

1 stop13h 30m

$125

MiamiDes Moines

MIA - DSM

MIADSM

Miami

Tue 6/17

1:21 pm-10:45 pm

2 stops10h 24m

$179

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/16

Showing 1-10 of 12 results
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Best time to book a flight from Key Largo to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Key Largo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Key Largo to Des Moines

What is the cheapest month to book a flight from Key Largo to Des Moines?

Currently, August is the cheapest month in which you can book a flight from Key Largo to Des Moines (average of $336). Flying from Key Largo to Des Moines in June is currently the most expensive (average of $422). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from KE9 to DSM?

Find hourly flight availability from Key Largo to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 17, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Key Largo to Des Moines as you normally would.

Rainfall in Des Moines by month

Plan your trip to Des Moines by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Des Moines ranges from 1.0 - 4.9 inches per month. June is typically the wettest month, when rainfall can reach 4.9 in. January is typically the driest time to visit Des Moines when rainfall is around 1.0 in.

Temperature in Des Moines by month

Plan your trip to Des Moines by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Des Moines, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 77.0 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 23.0 F).

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated April 17, 2025.
Get a feel of what it's like to fly with Southwest, Delta and United Airlines from Key Largo to Des Moines by reading reviews from past customers. In addition to providing an overall rating, users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,280 reviews

Comfort

8.0

Overall

8.0

Food

7.1

Crew

8.6

Boarding

8.2

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Southwest
8.0
Very good
4,280 reviews
Southwest
8.0
Very good
4,280 reviews

Comfort

8.0

Overall

8.0

Food

7.1

Crew

8.6

Boarding

8.2

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Delta
8.0
Very good
7,917 reviews
Southwest
8.0
Very good
4,280 reviews

Comfort

8.0

Overall

8.0

Food

7.1

Crew

8.6

Boarding

8.2

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
United Airlines
7.4
Good
8,667 reviews
Southwest
8.0
Very good
4,280 reviews

Comfort

8.0

Overall

8.0

Food

7.1

Crew

8.6

Boarding

8.2

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,280 reviews

Comfort

8.0

Overall

8.0

Food

7.1

Crew

8.6

Boarding

8.2

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Frontier
6.0
Okay
3,281 reviews
Southwest
8.0
Very good
4,280 reviews

Comfort

8.0

Overall

8.0

Food

7.1

Crew

8.6

Boarding

8.2

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.

Related info for your journey

Find useful and relevant information for your journey from Key Largo to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Des Moines from Key Largo?

    Des Moines (DSM), located 3.6 mi from the city center, is the airport you fly into when you book flights from Key Largo to Des Moines. 4 airlines have flights to Des Moines from Key Largo on a regular basis. Booking flights from Key Largo to Des Moines should not be difficult; the airport handles an average of 0 inbound flights from Key Largo per day.

  • What are the cheapest airlines to fly from Key Largo to Des Moines one-way?

    The cheapest airlines for a one-way flight from Key Largo to Des Moines are Frontier ($95), Southwest ($100), and United Airlines ($174).

  • What are the most reliable airlines from Key Largo to Des Moines?

    Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Key Largo to Des Moines on time: American Airlines (82%), Qatar Airways (82%), Envoy Air (82%).

  • Can I find deals for flights from Key Largo to Des Moines that include hotel bookings?

    Yes. In addition to deals on Key Largo to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Key Largo to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Key Largo to Des Moines.

  • Can I find deals for business class flights from Key Largo to Des Moines?

    Yes. Cheapflights offers flight deals from Key Largo to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Key Largo to Des Moines?

    Currently, August is the cheapest month in which you can book a flight from Key Largo to Des Moines (average of $336). Flying from Key Largo to Des Moines in June is currently the most expensive (average of $422). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Key Largo?

Book flights to Key Largo if you plan to visit one of these locations
Ames
Altoona
Johnston
Boone
West Des Moines
Ankeny

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Top 4 airlines flying from Key Largo to Des Moines

Discover the top 4 airlines that operate flights from Key Largo to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$108Average$177FlexibilityNo cancel feeOn-time88%
DeltaCheapest$236Average$377FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$271Average$419FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$331Average$453FlexibilityNo cancel feeOn-time69%

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