What are the cheapest airlines to fly from Key Largo to Des Moines one-way?

The cheapest airlines for a one-way flight from Key Largo to Des Moines are United Airlines ($150), American Airlines ($154), and Frontier ($185).

What is the cheapest day to fly from Key Largo to Des Moines?

Travelers seeking maximum savings on their Key Largo to Des Moines flight should consider departing on Friday at noon when fares are most often at their lowest. Sunday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

What are the cheapest flights from Key Largo to Des Moines?

While on average a flight from Key Largo to Des Moines is generally $736, our data shows the cheapest flight currently is $457. When looking at the most popular route, (Miami - Des Moines), you can expect to pay $229 for that flight.

What are the most reliable airlines from Key Largo to Des Moines?

Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Key Largo to Des Moines on time: American Airlines (82%), Qatar Airways (82%), Envoy Air (82%).

What are the most popular airlines that fly from Key Largo to Des Moines?

Consider American Airlines, Delta or United Airlines when booking your flight. These represent the most popular airlines when flying from Key Largo to Des Moines.

What is the cheapest month to fly from Key Largo to Des Moines?

November is one of the best times of the year to fly to Des Moines from Key Largo. Prices for November average $400 per person but you can even find prices for as low as $250. The most expensive prices can be found in the month of June. Opting for a November flight can save you 18% on your journey compared to booking in June

What airport do you fly into for flights to Des Moines from Key Largo?

Des Moines (DSM), located 3.6 mi from the city center, is the airport you fly into when you book flights from Key Largo to Des Moines. 4 airlines have flights to Des Moines from Key Largo on a regular basis. Booking flights from Key Largo to Des Moines should not be difficult; the airport handles an average of 1 inbound flight from Key Largo per day.

Can I find deals for flights from Key Largo to Des Moines that include hotel bookings?

Yes. In addition to deals on Key Largo to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Key Largo to Des Moines?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Key Largo to Des Moines.

Can I find deals for business class flights from Key Largo to Des Moines?

Yes. Cheapflights offers flight deals from Key Largo to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$150+ Flights from Key Largo to Des Moines

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Cheap flight deals from Key Largo to Des Moines

Most accurate provider	FlightHub 3 stars
Most trusted provider	FlightHub 3 stars
Round-trip from	$219 (United Airlines)
One-way from	$150 (United)
Popular in	June
Cheapest in	November
Average price	$397

Provider with most accurate pricing for Miami-Des Moines flight deals.

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Provider most trusted by Cheapflights users for Miami-Des Moines flights.

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From Key Largo to Des Moines

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One-way flight from Key Largo to Des Moines

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High demand for flights, 1% potential price rise

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Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).

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Average for round-trip flights in March 2025

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Find flight deals from Key Largo to Des Moines

Cheapest flights from Key Largo to Des Moines
Explore the most affordable flight options available from Key Largo to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 28, 2025.

Fri 4/49:20 amMIA - DSM

1 stop7h 54mUnited Airlines

Sun 4/67:45 amDSM - MIA

1 stop6h 10mUnited Airlines

Deal found 3/26

$219

Fri 8/297:25 amMIA - DSM

1 stop7h 39mDelta

Mon 9/81:31 pmDSM - MIA

1 stop8h 24mDelta

Deal found 3/26

$229

Wed 3/267:40 pmMIA - DSM

Nonstop3h 54mAmerican Airlines

Tue 4/16:00 amDSM - MIA

Nonstop3h 19mAmerican Airlines

Deal found 3/25

$271

Fri 8/111:30 amMIA - DSM

2 stops13h 20mSouthwest

Tue 8/58:25 amDSM - MIA

1 stop4h 40mSouthwest

Deal found 3/26

$307

Thu 4/178:58 amMIA - DSM

2 stops30h 02mMultiple Airlines

Sun 4/207:47 pmDSM - MIA

3 stops35h 06mMultiple Airlines

Deal found 3/27

$357

Best flights from Key Largo to Des Moines
Discover carefully curated flight deals from Key Largo to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 28, 2025.

Fri 4/49:20 amMIA - DSM

1 stop7h 54mUnited Airlines

Sun 4/67:45 amDSM - MIA

1 stop6h 10mUnited Airlines

Deal found 3/26

$219

Fri 5/211:25 amMIA - DSM

1 stop8h 49mDelta

Wed 5/77:11 amDSM - MIA

1 stop8h 29mDelta

Deal found 3/26

$262

Thu 4/178:58 amMIA - DSM

2 stops30h 02mMultiple Airlines

Sun 4/207:47 pmDSM - MIA

3 stops35h 06mMultiple Airlines

Deal found 3/27

$357

Thu 4/37:39 pmMIA - DSM

Nonstop3h 54mAmerican Airlines

Sun 4/62:12 pmDSM - MIA

1 stop8h 17mAmerican Airlines

Deal found 3/26

$360

Thu 6/1211:30 amMIA - DSM

2 stops13h 20mSouthwest

Sat 6/146:00 amDSM - MIA

1 stop11h 05mSouthwest

Deal found 3/27

$458

Last-minute flights from Key Largo to Des Moines
Discover last-minute flight deals from Key Largo to Des Moines. Data last updated March 28, 2025 and is based on user searches.

Thu 4/37:39 pmMIA - DSM

Nonstop3h 54mAmerican Airlines

Sun 4/62:12 pmDSM - MIA

1 stop8h 17mAmerican Airlines

Deal found 3/26

$360

Thu 4/36:00 amMIA - DSM

1 stop5h 37mDelta

Sun 4/66:35 pmDSM - MIA

1 stop5h 17mDelta

Deal found 3/27

$521

Fri 4/49:20 amMIA - DSM

1 stop7h 54mUnited Airlines

Sun 4/67:45 amDSM - MIA

1 stop6h 10mUnited Airlines

Deal found 3/26

$219

Fri 4/47:20 amMIA - DSM

1 stop15h 30mMultiple Airlines

Sun 4/61:27 pmDSM - MIA

1 stop19h 03mMultiple Airlines

Deal found 3/27

$386

Thu 4/1710:25 amMIA - DSM

1 stop8h 12mDelta

Sun 4/2011:30 amDSM - MIA

1 stop5h 57mDelta

Deal found 3/27

$268

Thu 4/178:58 amMIA - DSM

2 stops30h 02mMultiple Airlines

Sun 4/207:47 pmDSM - MIA

3 stops35h 06mMultiple Airlines

Deal found 3/27

$357

One-way flights from Key Largo to Des Moines
Search for one-way flight options from Key Largo to Des Moines. Find affordable one-way fares based on user searches. Data last updated March 28, 2025.

Sat 4/129:20 amMIA - DSM

1 stop7h 49mUnited Airlines

Deal found 3/26

$150

Fri 5/167:20 pmMIA - DSM

1 stop5h 38mAmerican Airlines

Deal found 3/26

$154

Mon 4/216:21 amMIA - DSM

1 stop13h 58mFrontier

Deal found 3/26

$185

Sun 4/2010:51 pmMIA - DSM

3 stops20h 07mMultiple Airlines

Deal found 3/27

$225

Mon 6/912:45 pmMIA - DSM

2 stops12h 05mSouthwest

Deal found 3/27

$263

Mon 3/311:38 pmMIA - DSM

2 stops8h 42mDelta

Deal found 3/25

$773

Cheapflights Fare Finder

Use the filters below to find and compare flights from Key Largo to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MiamiDes Moines

MIA - DSM

MIADSM

Miami

Fri 4/4

9:20 am-4:14 pm

1 stop7h 54m

Des Moines

Sun 4/6

7:45 am-2:55 pm

1 stop6h 10m

$219

MiamiDes Moines

MIA - DSM

MIADSM

Miami

Fri 5/2

11:25 am-7:14 pm

1 stop8h 49m

Des Moines

Wed 5/7

7:11 am-4:40 pm

1 stop8h 29m

$262

MiamiDes Moines

MIA - DSM

MIADSM

Miami

Thu 4/17

8:58 am-2:00 pm

2 stops30h 02m

Des Moines

Sun 4/20

7:47 pm-7:53 am

3 stops35h 06m

$357

MiamiDes Moines

MIA - DSM

MIADSM

Miami

Thu 4/3

7:39 pm-10:33 pm

Nonstop3h 54m

Des Moines

Sun 4/6

2:12 pm-11:29 pm

1 stop8h 17m

$360

MiamiDes Moines

MIA - DSM

MIADSM

Miami

Thu 6/12

11:30 am-11:50 pm

2 stops13h 20m

Des Moines

Sat 6/14

6:00 am-6:05 pm

1 stop11h 05m

$458

MiamiDes Moines

MIA - DSM

MIADSM

Miami

Sat 4/12

9:20 am-4:09 pm

1 stop7h 49m

$150

MiamiDes Moines

MIA - DSM

MIADSM

Miami

Fri 5/16

7:20 pm-11:58 pm

1 stop5h 38m

$154

MiamiDes Moines

MIA - DSM

MIADSM

Miami

Mon 4/21

6:21 am-7:19 pm

1 stop13h 58m

$185

MiamiDes Moines

MIA - DSM

MIADSM

Miami

Sun 4/20

10:51 pm-5:58 pm

3 stops20h 07m

$225

MiamiDes Moines

MIA - DSM

MIADSM

Miami

Mon 6/9

12:45 pm-11:50 pm

2 stops12h 05m

$263

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/26

Showing 1-10 of 11 results

Best time to book a flight from Key Largo to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Key Largo with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Key Largo to Des Moines

What is the cheapest month to book a flight from Key Largo to Des Moines?

Currently, August is the cheapest month in which you can book a flight from Key Largo to Des Moines (average of $336). Flying from Key Largo to Des Moines in June is currently the most expensive (average of $422). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from KE9 to DSM?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Key Largo to Des Moines as you normally would.

Rainfall in Des Moines by month

In terms of precipitation, rainfall in Des Moines ranges from 1.0 - 4.9 inches per month. June is typically the wettest month, when rainfall can reach 4.9 in. January is typically the driest time to visit Des Moines when rainfall is around 1.0 in.

Temperature in Des Moines by month

If weather is an important factor for your trip to Des Moines, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 77.0 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 23.0 F).

Reviews of airlines servicing Des Moines

Southwest

8.1

Very good

4,273 reviews

Reviews

1 / 20

8.0

Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.

Southwest

8.1

Very good

4,273 reviews

Southwest

8.1

Very good

4,273 reviews

Reviews

1 / 20

8.0

Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.

Delta

8.0

Very good

7,896 reviews

Southwest

8.1

Very good

4,273 reviews

Reviews

1 / 20

8.0

Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.

United Airlines

7.4

Good

8,603 reviews

Southwest

8.1

Very good

4,273 reviews

Reviews

1 / 20

8.0

Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.

American Airlines

7.2

Good

10,000 reviews

Southwest

8.1

Very good

4,273 reviews

Reviews

1 / 20

8.0

Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.

Frontier

6.0

Okay

3,271 reviews

Southwest

8.1

Very good

4,273 reviews

Reviews

1 / 20

8.0

Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.

Related info for your journey

What airport do you fly into for flights to Des Moines from Key Largo?
Des Moines (DSM), located 3.6 mi from the city center, is the airport you fly into when you book flights from Key Largo to Des Moines. 4 airlines have flights to Des Moines from Key Largo on a regular basis. Booking flights from Key Largo to Des Moines should not be difficult; the airport handles an average of 1 inbound flight from Key Largo per day.
What are the cheapest airlines to fly from Key Largo to Des Moines one-way?
The cheapest airlines for a one-way flight from Key Largo to Des Moines are United Airlines ($150), American Airlines ($154), and Frontier ($185).
What are the most reliable airlines from Key Largo to Des Moines?
Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Key Largo to Des Moines on time: American Airlines (82%), Qatar Airways (82%), Envoy Air (82%).
What are the cheapest flights from Key Largo to Des Moines?
While on average a flight from Key Largo to Des Moines is generally $736, our data shows the cheapest flight currently is $457. When looking at the most popular route, (Miami - Des Moines), you can expect to pay $229 for that flight.
Can I find deals for flights from Key Largo to Des Moines that include hotel bookings?
Yes. In addition to deals on Key Largo to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Key Largo to Des Moines?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Key Largo to Des Moines.
Can I find deals for business class flights from Key Largo to Des Moines?
Yes. Cheapflights offers flight deals from Key Largo to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Key Largo to Des Moines?
Currently, August is the cheapest month in which you can book a flight from Key Largo to Des Moines (average of $336). Flying from Key Largo to Des Moines in June is currently the most expensive (average of $422). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Ames

Altoona

Johnston

Boone

West Des Moines

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Other flights to Des Moines

Top 4 airlines flying from Key Largo to Des Moines

Airline	Cheapest	Average	Flexibility	On-time
Allegiant Air	Cheapest$124	Average$176	FlexibilityNo cancel fee	On-time88%
Delta	Cheapest$125	Average$375	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$271	Average$418	FlexibilityNo cancel fee	On-time71%
United Airlines	Cheapest$278	Average$453	FlexibilityNo cancel fee	On-time69%

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$150+ Cheap flights from Key Largo, FL to Des Moines (DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/12. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Key Largo to Des Moines with Cheapflights

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Cheap flight deals from Key Largo to Des Moines

Keep the following information in mind while searching for Key Largo to Des Moines flight deals. Data was last updated March 28, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Key Largo to Des Moines

Cheapest flights from Key Largo to Des MoinesExplore the most affordable flight options available from Key Largo to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 28, 2025.

Explore the most affordable flight options available from Key Largo to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 28, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Key Largo to Des Moines that are best for you.

Best time to book a flight from Key Largo to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Key Largo with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Key Largo to Des Moines

What is the cheapest month to book a flight from Key Largo to Des Moines?

What is the cheapest time of day to fly from KE9 to DSM?

Find hourly flight availability from Key Largo to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 28, 2025.

Rainfall in Des Moines by month

Plan your trip to Des Moines by taking into account the average rainfall totals by month.

Temperature in Des Moines by month

Plan your trip to Des Moines by taking into account the average temperature totals by month.

Reviews of airlines servicing Des Moines

Related info for your journey

Find useful and relevant information for your journey from Key Largo to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to Des Moines from Key Largo?

What are the cheapest airlines to fly from Key Largo to Des Moines one-way?

What are the most reliable airlines from Key Largo to Des Moines?

What are the cheapest flights from Key Largo to Des Moines?

Can I find deals for flights from Key Largo to Des Moines that include hotel bookings?

How can I find direct flights from Key Largo to Des Moines?

Can I find deals for business class flights from Key Largo to Des Moines?

What is the cheapest month to book a flight from Key Largo to Des Moines?

Traveling to a place near Key Largo?

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Alternative routes for Key Largo to Des Moines

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Top 4 airlines flying from Key Largo to Des Moines

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Cheapest flights from Key Largo to Des Moines
Explore the most affordable flight options available from Key Largo to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 28, 2025.