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$159+ Cheap flights from Fort Myers to Des Moines (RSW - DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/15. Fares are subject to change and may not be available on all flights or dates of travel.
RSW — DSM
Mar 31 — Apr 71
Mon 3/31
Mon 4/7
1 adult, Economy
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Cheap flight deals from Fort Myers to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Fort Myers (RSW) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 26, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$317
(Delta)

One-way from

$159
(American Airlines)

Popular in

October

Cheapest in

February

Average price

$366
Provider with most accurate pricing for Fort Myers SW Florida Intl-Des Moines flight deals.
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Provider most trusted by Cheapflights users for Fort Myers SW Florida Intl-Des Moines flights.
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From Fort Myers SW Florida Intl to Des Moines
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One-way flight from Fort Myers SW Florida Intl to Des Moines
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Highest demand for flights based on searches. 19% potential increase in price ($108 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($22 potential savings vs. average RT price).
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Average for round-trip flights in March 2025
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Find flight deals from Fort Myers to Des Moines

Cheapest flights from Fort Myers to Des Moines
Explore the most affordable flight options available from Fort Myers to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 26, 2025.

This Delta deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/56:31 amRSW - DSM
1 stop8h 33mDelta
Tue 8/126:30 pmDSM - RSW
1 stop5h 07mDelta
Deal found 3/25$317
This American Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/54:07 pmRSW - DSM
1 stop7h 54mAmerican Airlines
Tue 8/126:00 amDSM - RSW
2 stops11h 17mAmerican Airlines
Deal found 3/25$322
This Southwest deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/27:25 pmRSW - DSM
1 stop4h 50mSouthwest
Mon 7/75:25 amDSM - RSW
1 stop4h 35mSouthwest
Deal found 3/25$352
This United Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/312:30 pmRSW - DSM
1 stop6h 21mUnited Airlines
Wed 5/71:40 pmDSM - RSW
1 stop8h 54mUnited Airlines
Deal found 3/25$397
This Mytrip deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/25:45 amRSW - DSM
2 stops17h 36mMultiple Airlines
Sun 5/43:59 pmDSM - RSW
2 stops28h 10mMultiple Airlines
Deal found 3/25$406

Cheapflights Fare Finder

Customize your flight search to find flights from Fort Myers to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 26, 2025.
Use the filters below to find and compare flights from Fort Myers to Des Moines that are best for you.

Fly from

Fort Myers

Fly to

Des Moines

Route

Depart

Return

Price

Fort MyersDes Moines

RSW - DSM

RSWDSM

Fort Myers SW Florida Intl

Tue 8/5

6:31 am-2:04 pm

1 stop8h 33m

Des Moines

Tue 8/12

6:30 pm-12:37 am

1 stop5h 07m

$317

Fort MyersDes Moines

RSW - DSM

RSWDSM

Fort Myers SW Florida Intl

Tue 8/5

4:07 pm-11:01 pm

1 stop7h 54m

Des Moines

Tue 8/12

6:00 am-6:17 pm

2 stops11h 17m

$322

Fort MyersDes Moines

RSW - DSM

RSWDSM

Fort Myers SW Florida Intl

Wed 7/2

7:25 pm-11:15 pm

1 stop4h 50m

Des Moines

Mon 7/7

5:25 am-11:00 am

1 stop4h 35m

$352

Fort MyersDes Moines

RSW - DSM

RSWDSM

Fort Myers SW Florida Intl

Sat 5/3

12:30 pm-5:51 pm

1 stop6h 21m

Des Moines

Wed 5/7

1:40 pm-11:34 pm

1 stop8h 54m

$397

Fort MyersDes Moines

RSW - DSM

RSWDSM

Fort Myers SW Florida Intl

Fri 5/2

5:45 am-10:21 pm

2 stops17h 36m

Des Moines

Sun 5/4

3:59 pm-9:09 pm

2 stops28h 10m

$406

Fort MyersDes Moines

RSW - DSM

RSWDSM

Fort Myers SW Florida Intl

Tue 4/15

3:53 pm-10:53 pm

1 stop8h 00m

$159

Fort MyersDes Moines

RSW - DSM

RSWDSM

Fort Myers SW Florida Intl

Sat 4/12

5:45 am-3:27 pm

2 stops34h 42m

$181

Fort MyersDes Moines

RSW - DSM

RSWDSM

Fort Myers SW Florida Intl

Wed 6/4

5:28 pm-10:22 pm

1 stop5h 54m

$199

Fort MyersDes Moines

RSW - DSM

RSWDSM

Fort Myers SW Florida Intl

Sun 3/30

6:36 pm-10:56 pm

1 stop5h 20m

$500

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/25

Compare providers for flights from Fort Myers to Des Moines

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Fort Myers to Des Moines in March.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Fort Myers-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Fort Myers-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Fort Myers-Des Moines flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Fort Myers-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Fort Myers-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Fort Myers to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Fort Myers with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Fort Myers to Des Moines

What is the cheapest month to book a flight from Fort Myers to Des Moines?

Currently, August is the cheapest month in which you can book a flight from Fort Myers to Des Moines (average of $336). Flying from Fort Myers to Des Moines in June is currently the most expensive (average of $422). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from RSW to DSM?

Find hourly flight availability from Fort Myers to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 26, 2025.

One of the essential ways to save on airfare from Fort Myers to Des Moines is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight at noon could potentially save you up to 20% on airfare.

Rainfall in Des Moines by month

Plan your trip to Des Moines by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Des Moines ranges from 1.0 - 4.9 inches per month. June is typically the wettest month, when rainfall can reach 4.9 in. January is typically the driest time to visit Des Moines when rainfall is around 1.0 in.

Temperature in Des Moines by month

Plan your trip to Des Moines by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Des Moines, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 77.0 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 23.0 F).

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated March 26, 2025.
Southwest
8.1
Very good
4,273 reviews

Comfort

8.1

Crew

8.6

Overall

8.1

Boarding

8.2

Food

7.1

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Southwest
8.1
Very good
4,273 reviews
Southwest
8.1
Very good
4,273 reviews

Comfort

8.1

Crew

8.6

Overall

8.1

Boarding

8.2

Food

7.1

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Delta
8.0
Very good
7,891 reviews
Southwest
8.1
Very good
4,273 reviews

Comfort

8.1

Crew

8.6

Overall

8.1

Boarding

8.2

Food

7.1

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
United Airlines
7.4
Good
8,608 reviews
Southwest
8.1
Very good
4,273 reviews

Comfort

8.1

Crew

8.6

Overall

8.1

Boarding

8.2

Food

7.1

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.1
Very good
4,273 reviews

Comfort

8.1

Crew

8.6

Overall

8.1

Boarding

8.2

Food

7.1

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.

Related info for your journey

Find useful and relevant information for your journey from Fort Myers to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Fort Myers to Des Moines round-trip?

    Delta, at $317, was found to be the cheapest airline from Fort Myers to Des Moines.Alternate airlines to your destination round-trip include American Airlines and Southwest. You may be able to fly from Fort Myers to Des Moines for 30% less than the average price by searching for these airlines.

  • What are the cheapest airlines to fly from Fort Myers to Des Moines one-way?

    $159 is the cheapest one-way deal found within the past few days, from American Airlines. You may also be able to find cheap deals on United Airlines and Delta, with prices starting from $199 and $500, respectively.

  • Can I find deals for flights from Fort Myers to Des Moines that include hotel bookings?

    Yes. In addition to deals on Fort Myers to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Fort Myers to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Fort Myers to Des Moines.

  • Can I find deals for business class flights from Fort Myers to Des Moines?

    Yes. Cheapflights offers flight deals from Fort Myers to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Fort Myers to Des Moines?

    Currently, August is the cheapest month in which you can book a flight from Fort Myers to Des Moines (average of $336). Flying from Fort Myers to Des Moines in June is currently the most expensive (average of $422). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Fort Myers?

Book flights to Fort Myers if you plan to visit one of these locations
Ames
Altoona
Johnston
Boone
West Des Moines

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Top 3 airlines flying from Fort Myers to Des Moines

Discover the top 3 airlines that operate flights from Fort Myers to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 26, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$286Average$407FlexibilityNo cancel feeOn-time71%
DeltaCheapest$288Average$509FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$366Average$456FlexibilityNo cancel feeOn-time63%
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