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$129+ Cheap flights from Charleston to Des Moines (CHS - DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/14. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — DSM
Feb 27 — Mar 61
Thu 2/27
Thu 3/6
1 adult, Economy
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Cheap flight deals from Charleston to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Charleston (CHS) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 22, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$257
(Delta)

One-way from

$129
(American Airlines)

Popular in

February

Cheapest in

September

Average price

$646
Provider with most accurate pricing for Charleston-Des Moines flight deals.
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Provider most trusted by Cheapflights users for Charleston-Des Moines flights.
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From Charleston to Des Moines
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One-way flight from Charleston to Des Moines
Search Deals
Highest demand for flights based on searches. 15% potential increase in price ($88 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($18 potential savings vs. average RT price).
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Average for round-trip flights in February 2025
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Find flight deals from Charleston to Des Moines

Cheapest flights from Charleston to Des Moines
Explore the most affordable flight options available from Charleston to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 22, 2025.

This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/286:00 amCHS - DSM
1 stop9h 10mDelta
Mon 3/316:30 pmDSM - CHS
1 stop4h 27mDelta
Deal found 2/20$257
This Mytrip deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/157:00 amCHS - DSM
1 stop12h 05mMultiple Airlines
Fri 3/217:30 amDSM - CHS
2 stops28h 49mMultiple Airlines
Deal found 2/21$273
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/712:46 pmCHS - DSM
2 stops7h 35mAmerican Airlines
Tue 3/111:00 pmDSM - CHS
1 stop8h 02mAmerican Airlines
Deal found 2/20$282
This Southwest deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/287:40 amCHS - DSM
2 stops16h 20mSouthwest
Mon 3/315:45 amDSM - CHS
2 stops12h 35mSouthwest
Deal found 2/20$345
This United Airlines deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/244:00 pmCHS - DSM
1 stop25h 09mUnited Airlines
Mon 3/313:34 pmDSM - CHS
1 stop4h 53mUnited Airlines
Deal found 2/21$483

Find flights from Charleston to Des Moines within your budget

Customize your flight search to find flights from Charleston to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 22, 2025.

Fly from

Charleston

Fly to

Des Moines

Route

Depart

Return

Price

CharlestonDes Moines

CHS - DSM

CHSDSM

Charleston

Fri 3/28

6:00 am-2:10 pm

1 stop9h 10m

Des Moines

Mon 3/31

6:30 pm-11:57 pm

1 stop4h 27m

$257

CharlestonDes Moines

CHS - DSM

CHSDSM

Charleston

Sat 3/15

7:00 am-6:05 pm

1 stop12h 05m

Des Moines

Fri 3/21

7:30 am-1:19 pm

2 stops28h 49m

$273

CharlestonDes Moines

CHS - DSM

CHSDSM

Charleston

Fri 3/7

12:46 pm-7:21 pm

2 stops7h 35m

Des Moines

Tue 3/11

1:00 pm-10:02 pm

1 stop8h 02m

$282

CharlestonDes Moines

CHS - DSM

CHSDSM

Charleston

Fri 3/28

7:40 am-11:00 pm

2 stops16h 20m

Des Moines

Mon 3/31

5:45 am-7:20 pm

2 stops12h 35m

$345

CharlestonDes Moines

CHS - DSM

CHSDSM

Charleston

Mon 3/24

4:00 pm-4:09 pm

1 stop25h 09m

Des Moines

Mon 3/31

3:34 pm-9:27 pm

1 stop4h 53m

$483

CharlestonDes Moines

CHS - DSM

CHSDSM

Charleston

Fri 3/14

6:08 pm-10:04 pm

1 stop4h 56m

$129

CharlestonDes Moines

CHS - DSM

CHSDSM

Charleston

Fri 3/14

10:48 am-5:40 pm

3 stops31h 52m

$162

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/20

Compare providers for flights from Charleston to Des Moines

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Charleston to Des Moines in February.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Charleston-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Charleston-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Charleston-Des Moines flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Charleston-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Charleston-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Charleston to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Charleston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Charleston to Des Moines

Get recent, data-driven insights about flights from Charleston to Des Moines including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Charleston to Des Moines?

Currently, August is the cheapest month in which you can book a flight from Charleston to Des Moines (average of $336). Flying from Charleston to Des Moines in June is currently the most expensive (average of $422). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CHS to DSM?

Find hourly flight availability from Charleston to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 22, 2025.

When flying from Charleston to Des Moines, the time of day you fly usually plays a role in the price. Save by searching for a flight in the afternoon, which can drop the price by up to 16% versus a flight at noon.

Rainfall in Des Moines by month

Plan your trip to Des Moines by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Des Moines ranges from 1.0 - 4.9 inches per month. June is typically the wettest month, when rainfall can reach 4.9 in. January is typically the driest time to visit Des Moines when rainfall is around 1.0 in.

Temperature in Des Moines by month

Plan your trip to Des Moines by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Des Moines, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 77.0 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 23.0 F).

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated February 22, 2025.
Southwest
8.1
Very good
4,401 reviews

Entertainment

7.6

Crew

8.7

Boarding

8.2

Overall

8.1

Comfort

8.1

Food

7.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Southwest
8.1
Very good
4,401 reviews
Southwest
8.1
Very good
4,401 reviews

Entertainment

7.6

Crew

8.7

Boarding

8.2

Overall

8.1

Comfort

8.1

Food

7.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Delta
8.0
Very good
8,212 reviews
Southwest
8.1
Very good
4,401 reviews

Entertainment

7.6

Crew

8.7

Boarding

8.2

Overall

8.1

Comfort

8.1

Food

7.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

United Airlines
7.4
Good
8,759 reviews
Southwest
8.1
Very good
4,401 reviews

Entertainment

7.6

Crew

8.7

Boarding

8.2

Overall

8.1

Comfort

8.1

Food

7.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

American Airlines
7.2
Good
10,000 reviews
Southwest
8.1
Very good
4,401 reviews

Entertainment

7.6

Crew

8.7

Boarding

8.2

Overall

8.1

Comfort

8.1

Food

7.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Related info for your journey

Find useful and relevant information for your journey from Charleston to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Charleston to Des Moines round-trip?

    Currently priced at $257, Delta will fly you from Charleston to Des Moines and back. In addition to Delta, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from American Airlines and Southwest - these airlines can fly you to your destination from $282 and $345, respectively. Delta is 45% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Charleston to Des Moines that include hotel bookings?

    Yes. In addition to deals on Charleston to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charleston to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charleston to Des Moines.

  • Can I find deals for business class flights from Charleston to Des Moines?

    Yes. Cheapflights offers flight deals from Charleston to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Charleston to Des Moines?

    Currently, August is the cheapest month in which you can book a flight from Charleston to Des Moines (average of $336). Flying from Charleston to Des Moines in June is currently the most expensive (average of $422). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Charleston?

Book flights to Charleston if you plan to visit one of these locations
Ames
Altoona
Johnston
Boone
West Des Moines

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Top 2 airlines flying from Charleston to Des Moines

Discover the top 2 airlines that operate flights from Charleston to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 22, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$188Average$449FlexibilityNo cancel feeOn-time71%
DeltaCheapest$258Average$407FlexibilityNo cancel feeOn-timeN/A
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