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$33+ Cheap flights from South Carolina to Chicago (CHI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/10. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — CHI
Feb 28 — Mar 71
Fri 2/28
Fri 3/7
1 adult, Economy
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Cheap flight deals from South Carolina to Chicago

Keep the following information in mind while searching for South Carolina to Chicago flight deals. Data was last updated February 23, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$94
(FlightHub)

One-way from

$33
(Cheapflightsfares)

Popular in

December

Cheapest in

September

Average price

$321

Good round-trip deal

$349 or less

Good one-way deal

$149 or less
Provider with most accurate pricing for Myrtle Beach Intl-Chicago (CHI) flight deals.
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Provider most trusted by Cheapflights users for Myrtle Beach Intl-Chicago (CHI) flights.
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From South Carolina to Chicago (CHI)
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One-way flight from South Carolina to Chicago (CHI)
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Highest demand for flights based on searches. 22% potential increase in price ($81 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($15 potential savings vs. average RT price).
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Average for round-trip flights in February 2025
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Price to beat on a round-trip flight from South Carolina to Chicago (CHI).
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Price to beat on a one-way flight from South Carolina to Chicago (CHI).
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Find flight deals from South Carolina to Chicago

Cheapest flights from South Carolina to Chicago
Explore the most affordable flight options available from South Carolina to Chicago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 23, 2025.

This FlightHub deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/36:15 amMYR - ORD
1 stop5h 54mSpirit Airlines
Sun 4/69:08 pmORD - MYR
1 stop9h 46mSpirit Airlines
Deal found 2/21$94
This Cheapflightsfares deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/108:41 pmCLT - ORD
Nonstop2h 14mFrontier
Sun 4/134:40 pmORD - CLT
Nonstop2h 05mFrontier
Deal found 2/23$96
This FlightHub deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/47:17 amCLT - ORD
1 stop6h 20mMultiple Airlines
Thu 3/64:31 pmORD - CLT
Nonstop2h 10mMultiple Airlines
Deal found 2/21$100
This Expedia deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/86:00 amCLT - ORD
1 stop6h 36mSpirit Airlines
Tue 3/115:10 amORD - CLT
1 stop10h 57mSpirit Airlines
Deal found 2/22$102
This Frontier deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/812:55 pmCLT - MDW
1 stop7h 56mFrontier
Thu 4/1010:19 amMDW - CLT
1 stop9h 50mFrontier
Deal found 2/20$107
This American Airlines deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/2210:22 amMYR - ORD
1 stop6h 53mAmerican Airlines
Tue 3/256:05 amORD - MYR
1 stop6h 58mAmerican Airlines
Deal found 2/22$168
This American Airlines deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/117:20 amCLT - ORD
Nonstop2h 12mAmerican Airlines
Wed 3/125:00 amORD - CLT
Nonstop2h 01mAmerican Airlines
Deal found 2/23$177
This Southwest deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/276:20 amCLT - MDW
Nonstop2h 00mSouthwest
Mon 3/311:15 pmMDW - CLT
1 stop5h 25mSouthwest
Deal found 2/22$187
This United Airlines deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/1010:46 amCLT - ORD
Nonstop2h 17mUnited Airlines
Wed 3/121:00 pmORD - CLT
1 stop4h 46mUnited Airlines
Deal found 2/22$187
This Delta deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/166:04 amCLT - MDW
1 stop3h 36mDelta
Wed 4/239:52 amMDW - CLT
1 stop4h 02mDelta
Deal found 2/21$197
This United Airlines deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/106:11 amCAE - ORD
Nonstop2h 30mUnited Airlines
Thu 3/131:55 pmORD - CAE
Nonstop2h 00mUnited Airlines
Deal found 2/22$227
This United Airlines deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/216:00 amGSP - ORD
1 stop4h 38mUnited Airlines
Sat 3/295:50 pmORD - GSP
Nonstop1h 51mUnited Airlines
Deal found 2/22$237

Find flights from South Carolina to Chicago within your budget

Customize your flight search to find flights from South Carolina to Chicago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 23, 2025.

Fly from

South Carolina

Fly to

Chicago

Route

Depart

Return

Price

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Thu 4/3

6:15 am-11:09 am

1 stop5h 54m

Chicago O'Hare Intl

Sun 4/6

9:08 pm-7:54 am

1 stop9h 46m

$94

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

Thu 4/10

8:41 pm-9:55 pm

Nonstop2h 14m

Chicago O'Hare Intl

Sun 4/13

4:40 pm-7:45 pm

Nonstop2h 05m

$96

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

Wed 3/5

6:00 am-11:36 am

1 stop6h 36m

Chicago O'Hare Intl

Thu 3/6

4:31 pm-7:41 pm

Nonstop2h 10m

$100

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

Sat 3/8

6:00 am-11:36 am

1 stop6h 36m

Chicago O'Hare Intl

Tue 3/11

5:10 am-5:07 pm

1 stop10h 57m

$102

CharlotteChicago

CLT - MDW

CLTMDW

Charlotte Douglas

Tue 4/8

12:55 pm-7:51 pm

1 stop7h 56m

Chicago Midway

Thu 4/10

10:19 am-9:09 pm

1 stop9h 50m

$107

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Sat 3/22

10:22 am-4:15 pm

1 stop6h 53m

Chicago O'Hare Intl

Tue 3/25

6:05 am-2:03 pm

1 stop6h 58m

$168

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

Tue 3/11

7:20 am-8:32 am

Nonstop2h 12m

Chicago O'Hare Intl

Wed 3/12

5:00 am-8:01 am

Nonstop2h 01m

$177

CharlotteChicago

CLT - MDW

CLTMDW

Charlotte Douglas

Thu 3/27

6:20 am-7:20 am

Nonstop2h 00m

Chicago Midway

Mon 3/31

1:15 pm-7:40 pm

1 stop5h 25m

$187

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

Mon 3/10

10:46 am-12:03 pm

Nonstop2h 17m

Chicago O'Hare Intl

Wed 3/12

1:00 pm-6:46 pm

1 stop4h 46m

$187

CharlotteChicago

CLT - MDW

CLTMDW

Charlotte Douglas

Wed 4/16

6:04 am-8:40 am

1 stop3h 36m

Chicago Midway

Wed 4/23

9:52 am-2:54 pm

1 stop4h 02m

$197

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/22

Showing 1-10 of 60 results
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Best time to book a flight from South Carolina to Chicago

Have a flexible travel schedule? Discover the best time to fly to Chicago from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from South Carolina to Chicago

Get recent, data-driven insights about flights from South Carolina to Chicago including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from South Carolina to Chicago?

Currently, August is the cheapest month in which you can book a flight from South Carolina to Chicago (average of $245). Flying from South Carolina to Chicago in March is currently the most expensive (average of $321). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to CHI?

Find hourly flight availability from South Carolina to Chicago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 23, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from South Carolina to Chicago as you normally would.

Weekly flight availability from South Carolina to Chicago

Explore weekly flight availability from South Carolina to Chicago. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated February 23, 2025.

The most flights from USSC to CHI are scheduled on a Monday (19 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (14 on average).

Rainfall in Chicago by month

Plan your trip to Chicago by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Chicago ranges from 1.7 - 4.9 inches per month. August is typically the wettest month, when rainfall can reach 4.9 in. January is typically the driest time to visit Chicago when rainfall is around 1.7 in.

Temperature in Chicago by month

Plan your trip to Chicago by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Chicago, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 23.0 F).

Reviews of airlines servicing Chicago

Get insights into the airlines that provide service to Chicago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Chicago. Reviews last updated February 23, 2025.
Get a feel of what it's like to fly with Southwest, Delta and JetBlue from South Carolina to Chicago by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
4,387 reviews

Overall

8.1

Entertainment

7.6

Crew

8.7

Food

7.1

Boarding

8.2

Comfort

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Southwest
8.1
Very good
4,387 reviews
Southwest
8.1
Very good
4,387 reviews

Overall

8.1

Entertainment

7.6

Crew

8.7

Food

7.1

Boarding

8.2

Comfort

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Delta
8.0
Very good
8,203 reviews
Southwest
8.1
Very good
4,387 reviews

Overall

8.1

Entertainment

7.6

Crew

8.7

Food

7.1

Boarding

8.2

Comfort

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

JetBlue
7.4
Good
3,065 reviews
Southwest
8.1
Very good
4,387 reviews

Overall

8.1

Entertainment

7.6

Crew

8.7

Food

7.1

Boarding

8.2

Comfort

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

United Airlines
7.4
Good
8,754 reviews
Southwest
8.1
Very good
4,387 reviews

Overall

8.1

Entertainment

7.6

Crew

8.7

Food

7.1

Boarding

8.2

Comfort

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Allegiant Air
7.3
Good
764 reviews
Southwest
8.1
Very good
4,387 reviews

Overall

8.1

Entertainment

7.6

Crew

8.7

Food

7.1

Boarding

8.2

Comfort

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Chicago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from South Carolina to Chicago one-way?

    $33 is the cheapest one-way deal found within the past few days, from Spirit Airlines. You may also be able to find cheap deals on Frontier and Allegiant Air, with prices starting from $44 and $49, respectively.

  • What are the most popular routes from South Carolina to Chicago?

    While some choose either Charlotte Douglas - Chicago Midway or Charleston - Chicago O'Hare Intl, Charlotte Douglas - Chicago O'Hare Intl is the most popular route from South Carolina to Chicago.

  • What are the most reliable airlines from South Carolina to Chicago?

    Consider ANA (84%), Air New Zealand (81%) or Air Canada (81%) when booking your flight. These represent the most reliable airlines when flying from South Carolina to Chicago.

  • What are the cheapest flights from South Carolina to Chicago?

    The cheapest flight price from South Carolina to Chicago is $139. On average you can expect to pay $1,020. The most popular route, (Charlotte Douglas - Chicago O'Hare Intl), can usually be booked for $78.

  • Can I find deals for flights from South Carolina to Chicago that include hotel bookings?

    Yes. In addition to deals on South Carolina to Chicago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Chicago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Chicago.

  • Can I find deals for business class flights from South Carolina to Chicago?

    Yes. Cheapflights offers flight deals from South Carolina to Chicago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Chicago?

    Currently, August is the cheapest month in which you can book a flight from South Carolina to Chicago (average of $245). Flying from South Carolina to Chicago in March is currently the most expensive (average of $321). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near South Carolina?

Book flights to South Carolina if you plan to visit one of these locations
Merrillville
New Buffalo
Hammond
Benton Harbor
Porter
Lansing
Valparaiso
Chesterton

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Alternative routes for South Carolina to Chicago

See prices for flight routes from nearby airports that may be better suited for you.
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Dulles Intl to Midway flights
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Seattle to Midway flights
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Atlanta to Midway flights
Dallas/Fort Worth to Midway flights
Hobby to Midway flights
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San Francisco to Midway flights
Newark to St. Louis flights
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Minneapolis to Midway flights
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Top 5 airlines flying from South Carolina to Chicago

Discover the top 5 airlines that operate flights from South Carolina to Chicago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 23, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$61Average$156FlexibilityNo cancel feeOn-time65%
United AirlinesCheapest$173Average$374FlexibilityNo cancel feeOn-time69%
DeltaCheapest$176Average$388FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$194Average$354FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$266Average$417FlexibilityNo cancel feeOn-time63%
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