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$59+ Cheap flights from South Carolina to Chicago (CHI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/1. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — CHI
Apr 5 — Apr 121
Sat 4/5
Sat 4/12
1 adult, Economy
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Cheap flight deals from South Carolina to Chicago

Keep the following information in mind while searching for South Carolina to Chicago flight deals. Data was last updated March 31, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$128
(Cheapflightsfares)

One-way from

$59
(Frontier)

Popular in

December

Cheapest in

September

Average price

$405

Good round-trip deal

$340 or less

Good one-way deal

$134 or less
Provider with most accurate pricing for Myrtle Beach Intl-Chicago (CHI) flight deals.
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Provider most trusted by Cheapflights users for Myrtle Beach Intl-Chicago (CHI) flights.
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From South Carolina to Chicago (CHI)
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One-way flight from South Carolina to Chicago (CHI)
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Highest demand for flights based on searches. 18% potential increase in price ($67 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($13 potential savings vs. average RT price).
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Average for round-trip flights in March 2025
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Price to beat on a round-trip flight from South Carolina to Chicago (CHI).
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Price to beat on a one-way flight from South Carolina to Chicago (CHI).
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Find flight deals from South Carolina to Chicago

Cheapest flights from South Carolina to Chicago
Explore the most affordable flight options available from South Carolina to Chicago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 31, 2025.

This Gotogate deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2311:10 amSAV - MDW
Nonstop2h 15mAllegiant Air
Mon 5/261:15 pmMDW - SAV
Nonstop2h 05mAllegiant Air
Deal found 3/31$122
This Kiwi.com deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/204:46 pmCLT - ORD
1 stop7h 18mMultiple Airlines
Sun 5/255:59 pmORD - CLT
Nonstop2h 10mMultiple Airlines
Deal found 3/31$128
This Cheapflightsfares deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/152:53 pmCLT - ORD
1 stop6h 15mSpirit Airlines
Tue 5/2012:41 pmORD - CLT
1 stop8h 19mSpirit Airlines
Deal found 3/29$129
This Cheapflightsfares deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/912:01 pmCLT - ORD
Nonstop2h 33mFrontier
Thu 5/226:03 pmORD - CLT
Nonstop2h 16mFrontier
Deal found 3/30$136
This Cheapflightsfares deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/97:44 amCLT - MDW
1 stop5h 40mFrontier
Sun 5/1110:55 amMDW - CLT
1 stop6h 01mFrontier
Deal found 3/30$156
This Southwest deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/286:25 amCLT - MDW
Nonstop2h 00mSouthwest
Tue 6/36:30 pmMDW - CLT
Nonstop1h 50mSouthwest
Deal found 3/30$177
This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1510:51 pmCLT - ORD
Nonstop2h 20mAmerican Airlines
Wed 6/116:25 pmORD - CLT
Nonstop2h 15mAmerican Airlines
Deal found 3/30$187
This Delta deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/288:20 amCLT - MDW
1 stop4h 33mDelta
Sat 5/316:00 amMDW - CLT
1 stop3h 50mDelta
Deal found 3/30$208
This Booking.com deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/233:12 pmSAV - MDW
1 stop5h 43mMultiple Airlines
Mon 5/261:15 pmMDW - SAV
Nonstop2h 05mMultiple Airlines
Deal found 3/31$212
This United Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/710:26 amCAE - ORD
1 stop5h 08mUnited Airlines
Sat 5/106:30 pmORD - CAE
Nonstop2h 09mUnited Airlines
Deal found 3/30$219
This Delta deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/267:10 amGSP - ORD
1 stop6h 29mDelta
Sat 5/311:10 amORD - GSP
1 stop5h 17mDelta
Deal found 3/30$222
This Delta deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/37:20 amGSP - MDW
1 stop6h 15mDelta
Sun 5/43:02 pmMDW - GSP
1 stop6h 21mDelta
Deal found 3/30$222

Cheapflights Fare Finder

Customize your flight search to find flights from South Carolina to Chicago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 31, 2025.
Use the filters below to find and compare flights from South Carolina to Chicago that are best for you.

Fly from

South Carolina

Fly to

Chicago

Route

Depart

Return

Price

SavannahChicago

SAV - MDW

SAVMDW

Savannah/Hilton Head

Fri 5/23

11:10 am-12:25 pm

Nonstop2h 15m

Chicago Midway

Mon 5/26

1:15 pm-4:20 pm

Nonstop2h 05m

$122

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

Wed 4/23

4:20 pm-9:26 pm

1 stop6h 06m

Chicago O'Hare Intl

Fri 4/25

8:00 am-11:05 am

Nonstop2h 05m

$128

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

Thu 5/15

9:40 am-2:06 pm

1 stop5h 26m

Chicago O'Hare Intl

Tue 5/20

12:41 pm-10:00 pm

1 stop8h 19m

$129

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

Fri 5/9

12:01 pm-1:34 pm

Nonstop2h 33m

Chicago O'Hare Intl

Thu 5/22

6:03 pm-9:19 pm

Nonstop2h 16m

$136

CharlotteChicago

CLT - MDW

CLTMDW

Charlotte Douglas

Fri 5/9

7:44 am-12:24 pm

1 stop5h 40m

Chicago Midway

Sun 5/11

10:55 am-5:56 pm

1 stop6h 01m

$156

CharlotteChicago

CLT - MDW

CLTMDW

Charlotte Douglas

Wed 5/28

6:25 am-7:25 am

Nonstop2h 00m

Chicago Midway

Tue 6/3

6:30 pm-9:20 pm

Nonstop1h 50m

$177

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

Thu 5/15

10:51 pm-12:11 am

Nonstop2h 20m

Chicago O'Hare Intl

Wed 6/11

6:25 pm-9:40 pm

Nonstop2h 15m

$187

CharlotteChicago

CLT - MDW

CLTMDW

Charlotte Douglas

Wed 5/28

8:20 am-11:53 am

1 stop4h 33m

Chicago Midway

Sat 5/31

6:00 am-10:50 am

1 stop3h 50m

$208

SavannahChicago

SAV - MDW

SAVMDW

Savannah/Hilton Head

Fri 5/23

3:12 pm-7:55 pm

1 stop5h 43m

Chicago Midway

Mon 5/26

1:15 pm-4:20 pm

Nonstop2h 05m

$212

ColumbiaChicago

CAE - ORD

CAEORD

Columbia Metropolitan

Wed 5/7

10:26 am-2:34 pm

1 stop5h 08m

Chicago O'Hare Intl

Sat 5/10

6:30 pm-9:39 pm

Nonstop2h 09m

$219

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/31

Showing 1-10 of 60 results
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Best time to book a flight from South Carolina to Chicago

Have a flexible travel schedule? Discover the best time to fly to Chicago from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Chicago

What is the cheapest month to book a flight from South Carolina to Chicago?

Currently, August is the cheapest month in which you can book a flight from South Carolina to Chicago (average of $245). Flying from South Carolina to Chicago in March is currently the most expensive (average of $323). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to CHI?

Find hourly flight availability from South Carolina to Chicago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 31, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from South Carolina to Chicago as you normally would.

Weekly flight availability from South Carolina to Chicago

Explore weekly flight availability from South Carolina to Chicago. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated March 31, 2025.

The most flights from USSC to CHI are scheduled on a Monday (20 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (7 on average).

Rainfall in Chicago by month

Plan your trip to Chicago by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Chicago ranges from 1.7 - 4.9 inches per month. August is typically the wettest month, when rainfall can reach 4.9 in. January is typically the driest time to visit Chicago when rainfall is around 1.7 in.

Temperature in Chicago by month

Plan your trip to Chicago by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Chicago, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 23.0 F).

Reviews of airlines servicing Chicago

Get insights into the airlines that provide service to Chicago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Chicago. Reviews last updated March 31, 2025.
Get a feel of what it's like to fly with Alaska Airlines, Southwest and Delta from South Carolina to Chicago by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
9,818 reviews

Crew

8.5

Entertainment

7.1

Overall

8.0

Comfort

7.9

Boarding

8.2

Food

7.1

Reviews

1 / 20
10.0
Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them
Alaska Airlines
8.0
Very good
9,818 reviews
Alaska Airlines
8.0
Very good
9,818 reviews

Crew

8.5

Entertainment

7.1

Overall

8.0

Comfort

7.9

Boarding

8.2

Food

7.1

Reviews

1 / 20
10.0
Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them
Southwest
8.0
Very good
4,275 reviews
Alaska Airlines
8.0
Very good
9,818 reviews

Crew

8.5

Entertainment

7.1

Overall

8.0

Comfort

7.9

Boarding

8.2

Food

7.1

Reviews

1 / 20
10.0
Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them
Delta
8.0
Very good
7,899 reviews
Alaska Airlines
8.0
Very good
9,818 reviews

Crew

8.5

Entertainment

7.1

Overall

8.0

Comfort

7.9

Boarding

8.2

Food

7.1

Reviews

1 / 20
10.0
Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them
United Airlines
7.4
Good
8,614 reviews
Alaska Airlines
8.0
Very good
9,818 reviews

Crew

8.5

Entertainment

7.1

Overall

8.0

Comfort

7.9

Boarding

8.2

Food

7.1

Reviews

1 / 20
10.0
Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them
JetBlue
7.3
Good
2,924 reviews
Alaska Airlines
8.0
Very good
9,818 reviews

Crew

8.5

Entertainment

7.1

Overall

8.0

Comfort

7.9

Boarding

8.2

Food

7.1

Reviews

1 / 20
10.0
Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Chicago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from South Carolina to Chicago one-way?

    $59 is the cheapest one-way deal found within the past few days, from Frontier. You may also be able to find cheap deals on Spirit Airlines and Allegiant Air, with prices starting from $63 and $81, respectively.

  • What are the most popular routes from South Carolina to Chicago?

    While some choose either Charleston - Chicago O'Hare Intl or Savannah/Hilton Head - Chicago O'Hare Intl, Charlotte Douglas - Chicago O'Hare Intl is the most popular route from South Carolina to Chicago.

  • What are the most reliable airlines from South Carolina to Chicago?

    Consider Emirates (100%), ANA (90%) or United Airlines (87%) when booking your flight. These represent the most reliable airlines when flying from South Carolina to Chicago.

  • What are the cheapest flights from South Carolina to Chicago?

    The cheapest flight price from South Carolina to Chicago is $137. On average you can expect to pay $1,367. The most popular route, (Charlotte Douglas - Chicago O'Hare Intl), can usually be booked for $102.

  • Can I find deals for flights from South Carolina to Chicago that include hotel bookings?

    Yes. In addition to deals on South Carolina to Chicago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Chicago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Chicago.

  • Can I find deals for business class flights from South Carolina to Chicago?

    Yes. Cheapflights offers flight deals from South Carolina to Chicago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Chicago?

    Currently, August is the cheapest month in which you can book a flight from South Carolina to Chicago (average of $245). Flying from South Carolina to Chicago in March is currently the most expensive (average of $323). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near South Carolina?

Book flights to South Carolina if you plan to visit one of these locations
Merrillville
New Buffalo
Hammond
Benton Harbor
Porter
Lansing
Valparaiso
Chesterton

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Alternative routes for South Carolina to Chicago

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from South Carolina to Chicago

Discover the top 5 airlines that operate flights from South Carolina to Chicago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$59Average$152FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$167Average$349FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$173Average$371FlexibilityNo cancel feeOn-time69%
DeltaCheapest$176Average$393FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$285Average$405FlexibilityNo cancel feeOn-time63%
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