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$269+ Cheap flights from Panama to Chicago (CHI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/19. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — CHI
Apr 29 — May 61
Tue 4/29
Tue 5/6
1 adult, Economy
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Cheap flight deals from Panama to Chicago

Keep the following information in mind while searching for Panama to Chicago flight deals. Data was last updated April 24, 2025.

Round-trip from

$414
(Kiwi.com)

One-way from

$269
(Mytrip)

Popular in

July

Cheapest in

April

Average price

$479

Good round-trip deal

$495 or less

Good one-way deal

$881 or less
From Panama to Chicago (CHI)
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One-way flight from Panama to Chicago (CHI)
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Highest demand for flights based on searches. 4% potential increase in price ($25 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Price to beat on a round-trip flight from Panama to Chicago (CHI).
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Price to beat on a one-way flight from Panama to Chicago (CHI).
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Find flight deals from Panama to Chicago

Cheapest flights from Panama to Chicago
Explore the most affordable flight options available from Panama to Chicago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 24, 2025.

This Priceline deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/53:20 amPTY - ORD
1 stop9h 55mAvianca
Wed 7/163:45 pmORD - PTY
2 stops23h 00mAvianca
Deal found 4/23$403
This eDestinos deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/17:55 amPTY - ORD
1 stop16h 18mUnited Airlines
Mon 6/306:00 amORD - PTY
1 stop12h 37mUnited Airlines
Deal found 4/23$427
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/1210:05 pmPTY - ORD
2 stops19h 36mMultiple Airlines
Thu 5/152:35 pmORD - PTY
1 stop9h 35mMultiple Airlines
Deal found 4/23$459
This Copa Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/277:55 amPTY - ORD
Nonstop5h 52mCopa Airlines
Mon 7/141:07 amORD - PTY
Nonstop5h 16mCopa Airlines
Deal found 4/23$480
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/62:20 pmPTY - MDW
1 stop8h 02mDelta
Tue 5/136:00 amMDW - PTY
1 stop6h 48mDelta
Deal found 4/23$485
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/293:16 pmPTY - ORD
1 stop17h 46mAmerican Airlines
Sun 9/78:37 pmORD - PTY
2 stops15h 48mAmerican Airlines
Deal found 4/23$587
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/167:55 amPTY - MDW
2 stops12h 22mMultiple Airlines
Sun 6/226:20 amMDW - PTY
1 stop13h 13mMultiple Airlines
Deal found 4/23$743
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/288:10 amPTY - ORD
2 stops13h 44mDelta
Sat 1/37:00 amORD - PTY
2 stops12h 02mDelta
Deal found 4/23$841

Cheapflights Fare Finder

Customize your flight search to find flights from Panama to Chicago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2025.
Use the filters below to find and compare flights from Panama to Chicago that are best for you.

Fly from

Panama

Fly to

Chicago

Route

Depart

Return

Price

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Sun 6/8

3:20 am-1:15 pm

1 stop9h 55m

Chicago O'Hare Intl

Wed 6/11

3:45 pm-2:45 pm

2 stops23h 00m

$414

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Sun 6/1

7:55 am-12:13 am

1 stop16h 18m

Chicago O'Hare Intl

Mon 6/30

6:00 am-6:37 pm

1 stop12h 37m

$427

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Mon 5/12

10:05 pm-5:41 pm

2 stops19h 36m

Chicago O'Hare Intl

Thu 5/15

2:35 pm-12:10 am

1 stop9h 35m

$459

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Fri 6/27

7:55 am-1:47 pm

Nonstop5h 52m

Chicago O'Hare Intl

Tue 7/15

7:54 am-1:22 pm

Nonstop5h 28m

$480

Panama CityChicago

PTY - MDW

PTYMDW

Panama City Tocumen Intl

Tue 5/6

2:20 pm-10:22 pm

1 stop8h 02m

Chicago Midway

Tue 5/13

6:00 am-12:48 pm

1 stop6h 48m

$485

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Sat 6/21

1:50 pm-10:29 pm

1 stop8h 39m

Chicago O'Hare Intl

Sun 7/20

5:15 am-2:15 pm

2 stops9h 00m

$600

Panama CityChicago

PTY - MDW

PTYMDW

Panama City Tocumen Intl

Mon 6/16

7:55 am-8:17 pm

2 stops12h 22m

Chicago Midway

Sun 6/22

6:20 am-7:33 pm

1 stop13h 13m

$743

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Tue 6/17

3:06 pm-2:10 pm

1 stop23h 04m

Chicago O'Hare Intl

Sat 6/21

1:57 am-1:47 pm

1 stop11h 50m

$1,141

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Sat 7/19

3:20 am-1:15 pm

1 stop9h 55m

$269

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Tue 7/22

11:20 am-8:51 am

2 stops21h 31m

$313

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/23

Showing 1-10 of 15 results
1
2

Best time to book a flight from Panama to Chicago

Have a flexible travel schedule? Discover the best time to fly to Chicago from Panama with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to Chicago

What is the cheapest month to book a flight from Panama to Chicago?

Currently, August is the cheapest month in which you can book a flight from Panama to Chicago (average of $245). Flying from Panama to Chicago in March is currently the most expensive (average of $321). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PA to CHI?

Find hourly flight availability from Panama to Chicago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 24, 2025.

Unlike in the morning, when flights are generally more expensive, you can save up to 25% on flights from Panama to Chicago by exploring options for tickets at noon.

Weekly flight availability from Panama to Chicago

Explore weekly flight availability from Panama to Chicago. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated April 24, 2025.

The most flights from PA0 to CHI are scheduled on a Monday (2 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (2 on average).

Rainfall in Chicago by month

Plan your trip to Chicago by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Chicago ranges from 1.7 - 4.9 inches per month. August is typically the wettest month, when rainfall can reach 4.9 in. January is typically the driest time to visit Chicago when rainfall is around 1.7 in.

Temperature in Chicago by month

Plan your trip to Chicago by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Chicago, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 23.0 F).

Reviews of airlines servicing Chicago

Get insights into the airlines that provide service to Chicago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Chicago. Reviews last updated April 24, 2025.
To help decide which airline to fly from Panama to Chicago, see what other customers have to say about Delta, Copa Airlines and Aeromexico. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,920 reviews

Comfort

7.9

Entertainment

7.9

Overall

8.0

Boarding

8.2

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
8.0
Very good
7,920 reviews
Delta
8.0
Very good
7,920 reviews

Comfort

7.9

Entertainment

7.9

Overall

8.0

Boarding

8.2

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Copa Airlines
7.6
Good
1,411 reviews
Delta
8.0
Very good
7,920 reviews

Comfort

7.9

Entertainment

7.9

Overall

8.0

Boarding

8.2

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Aeromexico
7.5
Good
1,700 reviews
Delta
8.0
Very good
7,920 reviews

Comfort

7.9

Entertainment

7.9

Overall

8.0

Boarding

8.2

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
United Airlines
7.4
Good
8,685 reviews
Delta
8.0
Very good
7,920 reviews

Comfort

7.9

Entertainment

7.9

Overall

8.0

Boarding

8.2

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,920 reviews

Comfort

7.9

Entertainment

7.9

Overall

8.0

Boarding

8.2

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Panama to Chicago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Panama to Chicago one-way?

    To fly one-way, consider booking your trip with Avianca, which is currently one of the cheapest options available, starting at $269. United Airlines flights start at $796 while deals on Copa Airlines start at $892 one-way.

  • What are the most popular routes from Panama to Chicago?

    The most popular flight routes from Panama to Chicago are Panama City Tocumen Intl - Chicago O'Hare Intl, Panama City Tocumen Intl - Chicago Midway and Panama City Marcos A. Gelabert Intl - Chicago O'Hare Intl.

  • What are the most reliable airlines from Panama to Chicago?

    No one likes to see their flight delayed. When booking a flight from Panama to Chicago consider choosing EVA Air (89%), Copa Airlines (82%) or United Airlines (82%) as they are the most reliable in getting you off to your destination on time.

  • What are the cheapest flights from Panama to Chicago?

    The cheapest flight price from Panama to Chicago is $280. On average you can expect to pay $1,654. The most popular route, (Panama City Tocumen Intl - Chicago O'Hare Intl), can usually be booked for $472.

  • Can I find deals for flights from Panama to Chicago that include hotel bookings?

    Yes. In addition to deals on Panama to Chicago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama to Chicago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to Chicago.

  • Can I find deals for business class flights from Panama to Chicago?

    Yes. Cheapflights offers flight deals from Panama to Chicago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to Chicago?

    Currently, August is the cheapest month in which you can book a flight from Panama to Chicago (average of $245). Flying from Panama to Chicago in March is currently the most expensive (average of $321). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Panama?

Book flights to Panama if you plan to visit one of these locations
Merrillville
Hammond
Benton Harbor
Porter
Lansing
Valparaiso
Chesterton

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Alternative routes for Panama to Chicago

See prices for flight routes from nearby airports that may be better suited for you.
Guatemala City to O'Hare Intl flights
San José to O'Hare Intl flights
Guatemala City to Midway flights
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San Salvador to O'Hare Intl flights
San José to Midway flights
San José to St. Louis flights
San Pedro Sula to O'Hare Intl flights
Philip S.W.Goldson to O'Hare Intl flights
San Pedro Sula to Midway flights
Managua to O'Hare Intl flights
Managua to St. Louis flights
Panama City to St. Louis flights
Philip S.W.Goldson to Midway flights
Coxen Hole to O'Hare Intl flights
Liberia to O'Hare Intl flights
San Pedro Sula to St. Louis flights
Tegucigalpa to O'Hare Intl flights
Guatemala City to St. Louis flights
Tegucigalpa to St. Louis flights
Tegucigalpa to Midway flights
Managua to Midway flights

Top 3 airlines flying from Panama to Chicago

Discover the top 3 airlines that operate flights from Panama to Chicago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$450Average$559FlexibilityNo cancel feeOn-time70%
United AirlinesCheapest$485Average$692FlexibilityNo cancel feeOn-time69%
DeltaCheapest$492Average$671FlexibilityNo cancel feeOn-timeN/A

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