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$75+ Cheap flights from Knoxville (TYS) to Chicago (CHI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/6. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — CHI
Feb 25 — Mar 41
Tue 2/25
Tue 3/4
1 adult, Economy
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The best prices from Knoxville McGhee Tyson to Chicago are usually found in September or October, booked 64 days in advance, depart on a Friday or Thursday and return on a Monday

Cheap flight deals from Knoxville to Chicago

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Chicago (CHI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 20, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$189
(American Airlines)

One-way from

$75
(Frontier)

Popular in

March

Cheapest in

September

Average price

$206

Good round-trip deal

$287 or less

Good one-way deal

$278 or less
Provider with most accurate pricing for Knoxville McGhee Tyson-Chicago (CHI) flight deals.
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Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Chicago (CHI) flights.
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From Knoxville McGhee Tyson to Chicago (CHI)
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One-way flight from Knoxville McGhee Tyson to Chicago (CHI)
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Highest demand for flights based on searches. 6% potential increase in price ($18 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($9 potential savings vs. average RT price).
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Average for round-trip flights in February 2025
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Price to beat on a round-trip flight from Knoxville McGhee Tyson to Chicago (CHI).
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Price to beat on a one-way flight from Knoxville McGhee Tyson to Chicago (CHI).
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Find flight deals from Knoxville to Chicago

Cheapest flights from Knoxville to Chicago
Explore the most affordable flight options available from Knoxville to Chicago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 20, 2025.

This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/118:07 pmTYS - ORD
Nonstop2h 07mAmerican Airlines
Mon 4/144:56 pmORD - TYS
Nonstop1h 42mAmerican Airlines
Deal found 2/19$189
This Frontier deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/104:31 pmTYS - MDW
1 stop8h 50mFrontier
Sun 4/136:45 amMDW - TYS
1 stop8h 01mFrontier
Deal found 2/18$190
This United Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/237:00 amTYS - ORD
Nonstop2h 03mUnited Airlines
Sun 3/302:31 pmORD - TYS
Nonstop1h 52mUnited Airlines
Deal found 2/20$190
This Mytrip deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/127:15 amTYS - ORD
1 stop12h 11mMultiple Airlines
Tue 3/1812:31 pmORD - TYS
1 stop22h 29mMultiple Airlines
Deal found 2/18$194
This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/85:45 amTYS - MDW
1 stop4h 22mDelta
Tue 4/84:59 pmMDW - TYS
1 stop5h 43mDelta
Deal found 2/20$199
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/195:00 pmTYS - ORD
1 stop4h 58mDelta
Wed 3/268:25 amORD - TYS
1 stop7h 29mDelta
Deal found 2/19$199
This Frontier deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/204:23 pmTYS - ORD
1 stop9h 00mFrontier
Thu 3/276:45 amORD - TYS
1 stop7h 38mFrontier
Deal found 2/20$260
This Mytrip deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/176:15 pmTYS - MDW
1 stop24h 31mAllegiant Air
Thu 3/202:22 pmMDW - TYS
1 stop5h 32mAllegiant Air
Deal found 2/20$471

Find flights from Knoxville to Chicago within your budget

Customize your flight search to find flights from Knoxville to Chicago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.

Fly from

Knoxville

Fly to

Chicago

Route

Depart

Return

Price

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Fri 4/11

8:07 pm-9:14 pm

Nonstop2h 07m

Chicago O'Hare Intl

Mon 4/14

4:56 pm-7:38 pm

Nonstop1h 42m

$189

KnoxvilleChicago

TYS - MDW

TYSMDW

Knoxville McGhee Tyson

Thu 4/10

4:31 pm-12:21 am

1 stop8h 50m

Chicago Midway

Sun 4/13

6:45 am-3:46 pm

1 stop8h 01m

$190

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Sun 3/23

7:00 am-8:03 am

Nonstop2h 03m

Chicago O'Hare Intl

Sun 3/30

2:31 pm-5:23 pm

Nonstop1h 52m

$190

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Wed 3/12

7:15 am-6:26 pm

1 stop12h 11m

Chicago O'Hare Intl

Tue 3/18

12:31 pm-12:00 pm

1 stop22h 29m

$194

KnoxvilleChicago

TYS - MDW

TYSMDW

Knoxville McGhee Tyson

Tue 4/8

5:45 am-9:07 am

1 stop4h 22m

Chicago Midway

Tue 4/8

4:59 pm-11:42 pm

1 stop5h 43m

$199

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Wed 3/19

5:00 pm-8:58 pm

1 stop4h 58m

Chicago O'Hare Intl

Wed 3/26

8:25 am-4:54 pm

1 stop7h 29m

$199

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Thu 3/20

4:23 pm-12:23 am

1 stop9h 00m

Chicago O'Hare Intl

Thu 3/27

6:45 am-3:23 pm

1 stop7h 38m

$260

KnoxvilleChicago

TYS - MDW

TYSMDW

Knoxville McGhee Tyson

Mon 3/17

6:15 pm-5:46 pm

1 stop24h 31m

Chicago Midway

Thu 3/20

2:22 pm-8:54 pm

1 stop5h 32m

$471

KnoxvilleChicago

TYS - MDW

TYSMDW

Knoxville McGhee Tyson

Thu 3/6

4:23 pm-12:17 am

1 stop8h 54m

$75

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Thu 3/6

4:23 pm-12:23 am

1 stop9h 00m

$75

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/18

Showing 1-10 of 15 results
1
2

Compare providers for flights from Knoxville to Chicago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Chicago in February.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightnetworkPrice Accuracy-Trust Score*3 stars
MytripPrice Accuracy3 starsTrust Score*3 stars
CheapflightsfaresPrice Accuracy3 starsTrust Score*2 stars
Kiwi.comPrice Accuracy3 starsTrust Score*2 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Chicago flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Chicago flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Chicago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Chicago flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Chicago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Chicago

Have a flexible travel schedule? Discover the best time to fly to Chicago from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Knoxville to Chicago

Get recent, data-driven insights about flights from Knoxville to Chicago including ideal travel times, pricing trends, and more.

How far ahead should I book a flight from Knoxville to Chicago?

Use this chart to determine the optimal time to book a round-trip flight from Knoxville to Chicago. Price data was last updated on February 14, 2025.

The best time to book flights from Knoxville to Chicago is 64 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Knoxville to Chicago?

Currently, August is the cheapest month in which you can book a flight from Knoxville to Chicago (average of $245). Flying from Knoxville to Chicago in March is currently the most expensive (average of $321). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to CHI?

Find hourly flight availability from Knoxville to Chicago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 20, 2025.

It’s typically best to fly out from Knoxville to Chicago in the evening. Doing so could potentially save you 85% on the flight price compared to flying at noon, which is usually more expensive.

What is the cheapest day to fly from Knoxville to Chicago?

Use this chart to determine the cheapest time to fly round-trip from Knoxville to Chicago. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Knoxville to Chicago flight should consider departing on Friday evenings when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Knoxville to Chicago

Explore weekly flight availability from Knoxville to Chicago. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated February 20, 2025.

The most flights from TYS to CHI are scheduled on a Wednesday (24 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (13 on average).

Rainfall in Chicago by month

Plan your trip to Chicago by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Chicago ranges from 1.7 - 4.9 inches per month. August is typically the wettest month, when rainfall can reach 4.9 in. January is typically the driest time to visit Chicago when rainfall is around 1.7 in.

Temperature in Chicago by month

Plan your trip to Chicago by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Chicago, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 23.0 F).

Reviews of airlines servicing Chicago

Get insights into the airlines that provide service to Chicago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Chicago. Reviews last updated February 20, 2025.
Peruse reviews from past customers who have flown with Delta, United Airlines and Allegiant Air from Knoxville to Chicago to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
8,220 reviews

Entertainment

7.9

Overall

8.0

Food

7.3

Crew

8.5

Boarding

8.2

Comfort

8.0

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Delta
8.0
Very good
8,220 reviews
Delta
8.0
Very good
8,220 reviews

Entertainment

7.9

Overall

8.0

Food

7.3

Crew

8.5

Boarding

8.2

Comfort

8.0

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

United Airlines
7.4
Good
8,766 reviews
Delta
8.0
Very good
8,220 reviews

Entertainment

7.9

Overall

8.0

Food

7.3

Crew

8.5

Boarding

8.2

Comfort

8.0

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Allegiant Air
7.3
Good
765 reviews
Delta
8.0
Very good
8,220 reviews

Entertainment

7.9

Overall

8.0

Food

7.3

Crew

8.5

Boarding

8.2

Comfort

8.0

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
8,220 reviews

Entertainment

7.9

Overall

8.0

Food

7.3

Crew

8.5

Boarding

8.2

Comfort

8.0

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Frontier
6.0
Okay
3,355 reviews
Delta
8.0
Very good
8,220 reviews

Entertainment

7.9

Overall

8.0

Food

7.3

Crew

8.5

Boarding

8.2

Comfort

8.0

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Chicago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Chicago?

    If you book a flight to Chicago from Knoxville, you will be flying from McGhee Tyson, which is the city’s only airport. Knoxville McGhee Tyson (TYS) is located 11.3 mi from the center of Knoxville. There are 20 flights from McGhee Tyson to Chicago per day from 4 different airlines.

  • What are the cheapest airlines flying from Knoxville to Chicago round-trip?

    Our cheapest airline available from Knoxville to Chicago is American Airlines. Our recent data shows that you can find tickets from as low as $189 on this airline. Additional options worth looking into are Frontier and United Airlines, starting at $190 and $190 round-trip. American Airlines is currently priced 23% below the average price you’ll pay for this route.

  • What are the cheapest airlines to fly from Knoxville to Chicago one-way?

    The cheapest airline one-way is Frontier, with whom users have recently found tickets for as low as $75. However, be on the lookout for offers from American Airlines and Delta, as they are both options that can get you from Knoxville to Chicago for a low price.

  • What are the most reliable airlines from Knoxville to Chicago?

    The top 3 most reliable airlines when flying from Knoxville to Chicago are Emirates (100%), GoJet (100%) and United Airlines (93%).

  • What are the cheapest flights from Knoxville to Chicago?

    On average you can expect to pay $1,135 for a flight from Knoxville to Chicago. The cheapest flight overall is $114 while the most popular route, (Knoxville McGhee Tyson - Chicago O'Hare Intl) is currently priced at $179.

  • Can I find deals for flights from Knoxville to Chicago that include hotel bookings?

    Yes. In addition to deals on Knoxville to Chicago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Chicago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Chicago.

  • Can I find deals for business class flights from Knoxville to Chicago?

    Yes. Cheapflights offers flight deals from Knoxville to Chicago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Chicago?

    Currently, August is the cheapest month in which you can book a flight from Knoxville to Chicago (average of $245). Flying from Knoxville to Chicago in March is currently the most expensive (average of $321). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Merrillville
New Buffalo
Hammond
Benton Harbor
Porter
Lansing
Valparaiso
Chesterton

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Top 4 airlines flying from Knoxville to Chicago

Discover the top 4 airlines that operate flights from Knoxville to Chicago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$75Average$82FlexibilityNo cancel feeOn-time88%
American AirlinesCheapest$166Average$262FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$179Average$295FlexibilityNo cancel feeOn-time69%
DeltaCheapest$203Average$312FlexibilityNo cancel feeOn-timeN/A
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