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$87+ Cheap flights from Knoxville (TYS) to Chicago (CHI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/26. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — CHI
Apr 20 — Apr 271
Sun 4/20
Sun 4/27
1 adult, Economy
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Cheapflights Tip: The best prices from Knoxville McGhee Tyson to Chicago are usually found in September or October, booked 73 days in advance, depart on a Friday or Thursday and return on a Monday

Cheap flight deals from Knoxville to Chicago

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Chicago (CHI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 15, 2025.

Most accurate provider

Mytrip
3 stars

Most trusted provider

Mytrip
3 stars

Round-trip from

$189
(American Airlines)

One-way from

$87
(Mytrip)

Popular in

July

Cheapest in

September

Average price

$284

Good round-trip deal

$83 or less

Good one-way deal

$57 or less
Provider with most accurate pricing for Knoxville McGhee Tyson-Chicago (CHI) flight deals.
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Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Chicago (CHI) flights.
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From Knoxville McGhee Tyson to Chicago (CHI)
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One-way flight from Knoxville McGhee Tyson to Chicago (CHI)
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Highest demand for flights based on searches. 7% potential increase in price ($19 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($5 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Price to beat on a round-trip flight from Knoxville McGhee Tyson to Chicago (CHI).
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Price to beat on a one-way flight from Knoxville McGhee Tyson to Chicago (CHI).
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Find flight deals from Knoxville to Chicago

Cheapest flights from Knoxville to Chicago
Explore the most affordable flight options available from Knoxville to Chicago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 15, 2025.

This United Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/157:00 amTYS - ORD
Nonstop1h 57mUnited Airlines
Sun 5/187:30 amORD - TYS
Nonstop1h 45mUnited Airlines
Deal found 4/14$189
This Delta deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/87:05 amTYS - MDW
1 stop3h 35mDelta
Thu 5/296:00 amMDW - TYS
1 stop6h 19mDelta
Deal found 4/14$204
This American Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/21:56 pmTYS - ORD
Nonstop1h 58mAmerican Airlines
Sat 7/511:40 amORD - TYS
Nonstop1h 47mAmerican Airlines
Deal found 4/14$205
This Delta deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/1111:26 amTYS - ORD
1 stop7h 26mDelta
Sun 6/155:35 amORD - TYS
1 stop4h 33mDelta
Deal found 4/14$209
This Frontier deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/174:31 pmTYS - MDW
1 stop8h 50mFrontier
Sun 4/206:45 amMDW - TYS
1 stop8h 01mFrontier
Deal found 4/14$221
This Frontier deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/174:31 pmTYS - ORD
1 stop8h 39mFrontier
Sun 4/206:45 amORD - TYS
1 stop8h 01mFrontier
Deal found 4/14$221
This Mytrip deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/125:15 pmTYS - ORD
1 stop16h 35mMultiple Airlines
Thu 5/154:35 pmORD - TYS
1 stop18h 41mMultiple Airlines
Deal found 4/14$228
This Mytrip deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1510:00 amTYS - MDW
1 stop23h 52mAllegiant Air
Thu 5/2911:03 amMDW - TYS
1 stop26h 52mAllegiant Air
Deal found 4/14$297

Cheapflights Fare Finder

Customize your flight search to find flights from Knoxville to Chicago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 15, 2025.
Use the filters below to find and compare flights from Knoxville to Chicago that are best for you.

Fly from

Knoxville

Fly to

Chicago

Route

Depart

Return

Price

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Thu 5/15

7:00 am-7:57 am

Nonstop1h 57m

Chicago O'Hare Intl

Sun 5/18

7:30 am-10:15 am

Nonstop1h 45m

$189

KnoxvilleChicago

TYS - MDW

TYSMDW

Knoxville McGhee Tyson

Thu 5/8

7:05 am-9:40 am

1 stop3h 35m

Chicago Midway

Thu 5/29

6:00 am-1:19 pm

1 stop6h 19m

$204

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Wed 7/2

1:56 pm-2:54 pm

Nonstop1h 58m

Chicago O'Hare Intl

Sat 7/5

11:40 am-2:27 pm

Nonstop1h 47m

$205

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Wed 6/11

7:46 am-12:55 pm

1 stop6h 09m

Chicago O'Hare Intl

Mon 6/16

7:10 am-1:47 pm

1 stop5h 37m

$209

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Mon 5/12

5:15 pm-8:50 am

1 stop16h 35m

Chicago O'Hare Intl

Thu 5/15

4:35 pm-12:16 pm

1 stop18h 41m

$228

KnoxvilleChicago

TYS - MDW

TYSMDW

Knoxville McGhee Tyson

Fri 4/18

12:46 pm-12:21 am

1 stop12h 35m

Chicago Midway

Sun 4/20

6:45 am-3:46 pm

1 stop8h 01m

$242

KnoxvilleChicago

TYS - MDW

TYSMDW

Knoxville McGhee Tyson

Thu 5/15

10:00 am-8:52 am

1 stop23h 52m

Chicago Midway

Thu 5/29

11:03 am-2:55 pm

1 stop26h 52m

$297

KnoxvilleChicago

TYS - MDW

TYSMDW

Knoxville McGhee Tyson

Mon 5/26

1:31 pm-2:04 pm

Nonstop1h 33m

$87

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Tue 7/1

6:40 pm-7:35 pm

Nonstop1h 55m

$90

KnoxvilleChicago

TYS - MDW

TYSMDW

Knoxville McGhee Tyson

Tue 7/1

7:46 am-12:29 pm

1 stop5h 43m

$100

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/15

Showing 1-10 of 15 results
1
2

Compare providers for flights from Knoxville to Chicago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Chicago in April.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*2 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightnetworkPrice Accuracy-Trust Score*3 stars
MytripPrice Accuracy3 starsTrust Score*3 stars
CheapflightsfaresPrice Accuracy3 starsTrust Score*2 stars
Kiwi.comPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Chicago flights, users find the pricing of Mytrip to be most consistent on Cheapflights vs. Mytrip Users can find the same prices on Knoxville-Chicago flight deals on Cheapflights vs. Mytrip >95% of the time. Price accuracy is based on data collected from Knoxville-Chicago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Chicago flights, Cheapflights users trust Mytrip the most. Mytrip has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Chicago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Chicago

Have a flexible travel schedule? Discover the best time to fly to Chicago from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Chicago

How far ahead should I book a flight from Knoxville to Chicago?

Use this chart to determine the optimal time to book a round-trip flight from Knoxville to Chicago. Price data was last updated on April 11, 2025.

The best time to book flights from Knoxville to Chicago is 73 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Knoxville to Chicago?

Currently, August is the cheapest month in which you can book a flight from Knoxville to Chicago (average of $245). Flying from Knoxville to Chicago in March is currently the most expensive (average of $321). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to CHI?

Find hourly flight availability from Knoxville to Chicago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 15, 2025.

It’s typically best to fly out from Knoxville to Chicago in the evening. Doing so could potentially save you 51% on the flight price compared to flying at noon, which is usually more expensive.

What is the cheapest day to fly from Knoxville to Chicago?

Use this chart to determine the cheapest time to fly round-trip from Knoxville to Chicago. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Knoxville to Chicago flight should consider departing on Friday evenings when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Knoxville to Chicago

Explore weekly flight availability from Knoxville to Chicago. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated April 15, 2025.

The most flights from TYS to CHI are scheduled on a Monday (29 on average). You will have fewer flight options on Sunday, which is when the least amount of flights are scheduled (15 on average).

Rainfall in Chicago by month

Plan your trip to Chicago by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Chicago ranges from 1.7 - 4.9 inches per month. August is typically the wettest month, when rainfall can reach 4.9 in. January is typically the driest time to visit Chicago when rainfall is around 1.7 in.

Temperature in Chicago by month

Plan your trip to Chicago by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Chicago, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 23.0 F).

Reviews of airlines servicing Chicago

Get insights into the airlines that provide service to Chicago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Chicago. Reviews last updated April 15, 2025.
Peruse reviews from past customers who have flown with Delta, United Airlines and Allegiant Air from Knoxville to Chicago to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,917 reviews

Entertainment

7.9

Overall

8.0

Comfort

7.9

Food

7.3

Boarding

8.2

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
8.0
Very good
7,917 reviews
Delta
8.0
Very good
7,917 reviews

Entertainment

7.9

Overall

8.0

Comfort

7.9

Food

7.3

Boarding

8.2

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
United Airlines
7.4
Good
8,658 reviews
Delta
8.0
Very good
7,917 reviews

Entertainment

7.9

Overall

8.0

Comfort

7.9

Food

7.3

Boarding

8.2

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Allegiant Air
7.3
Good
734 reviews
Delta
8.0
Very good
7,917 reviews

Entertainment

7.9

Overall

8.0

Comfort

7.9

Food

7.3

Boarding

8.2

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,917 reviews

Entertainment

7.9

Overall

8.0

Comfort

7.9

Food

7.3

Boarding

8.2

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Frontier
6.0
Okay
3,281 reviews
Delta
8.0
Very good
7,917 reviews

Entertainment

7.9

Overall

8.0

Comfort

7.9

Food

7.3

Boarding

8.2

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Chicago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Chicago?

    If you book a flight to Chicago from Knoxville, you will be flying from McGhee Tyson, which is the city’s only airport. Knoxville McGhee Tyson (TYS) is located 11.3 mi from the center of Knoxville. There are 25 flights from McGhee Tyson to Chicago per day from 4 different airlines.

  • What are the cheapest airlines flying from Knoxville to Chicago round-trip?

    Our cheapest airline available from Knoxville to Chicago is American Airlines. Our recent data shows that you can find tickets from as low as $189 on this airline. Additional options worth looking into are United Airlines and Delta, starting at $199 and $204 round-trip. American Airlines is currently priced 23% below the average price you’ll pay for this route.

  • What are the cheapest airlines to fly from Knoxville to Chicago one-way?

    The cheapest airline one-way is Allegiant Air, with whom users have recently found tickets for as low as $87. However, be on the lookout for offers from American Airlines and Delta, as they are both options that can get you from Knoxville to Chicago for a low price.

  • What are the most reliable airlines from Knoxville to Chicago?

    The top 3 most reliable airlines when flying from Knoxville to Chicago are Avianca (91%), ANA (87%) and Republic Airways (83%).

  • What are the cheapest flights from Knoxville to Chicago?

    On average you can expect to pay $1,031 for a flight from Knoxville to Chicago. The cheapest flight overall is $115 while the most popular route, (Knoxville McGhee Tyson - Chicago O'Hare Intl) is currently priced at $189.

  • Can I find deals for flights from Knoxville to Chicago that include hotel bookings?

    Yes. In addition to deals on Knoxville to Chicago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Chicago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Chicago.

  • Can I find deals for business class flights from Knoxville to Chicago?

    Yes. Cheapflights offers flight deals from Knoxville to Chicago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Chicago?

    Currently, August is the cheapest month in which you can book a flight from Knoxville to Chicago (average of $245). Flying from Knoxville to Chicago in March is currently the most expensive (average of $321). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Merrillville
Hammond
Benton Harbor
Porter
Lansing
Valparaiso
Chesterton

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Top 4 airlines flying from Knoxville to Chicago

Discover the top 4 airlines that operate flights from Knoxville to Chicago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$75Average$81FlexibilityNo cancel feeOn-time88%
American AirlinesCheapest$163Average$259FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$181Average$299FlexibilityNo cancel feeOn-time69%
DeltaCheapest$187Average$293FlexibilityNo cancel feeOn-timeN/A

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