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Central America

$128+ Cheap flights from Missouri to Central America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/8. Fares are subject to change and may not be available on all flights or dates of travel.
STL — SJO
Apr 5 — Apr 121
Sat 4/5
Sat 4/12
1 adult, Economy
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Cheap flight deals from Missouri to Central America

Keep the following information in mind while searching for Missouri to Central America flight deals. Data was last updated March 31, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$311
(Kiwi.com)

One-way from

$128
(CheapOair)

Popular in

December

Cheapest in

September

Average price

$499
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From Missouri to Central America
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One-way flight from Missouri to Central America
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Highest demand for flights based on searches. 23% potential increase in price ($187 potential increase over avg. RT price).
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Cheapest flight prices on average. 9% potential price decrease ($53 potential savings vs. average RT price).
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Average for round-trip flights in March 2025
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Find flight deals from Missouri to Central America

Cheapest flights from Missouri to Central America
Explore the most affordable flight options available from Missouri to Central America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 31, 2025.

This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/226:10 pmSTL - SJO
1 stop18h 08mMultiple Airlines
Fri 4/2511:35 amSJO - STL
1 stop11h 29mMultiple Airlines
Deal found 3/30$311
This FlightHub deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/264:23 pmMCI - SJO
2 stops19h 55mSpirit Airlines
Sat 5/1011:32 amSJO - MCI
1 stop8h 58mSpirit Airlines
Deal found 3/30$312
This Delta deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/16:00 amSTL - SJO
1 stop6h 59mDelta
Tue 6/101:25 pmSJO - STL
1 stop9h 17mDelta
Deal found 3/29$342
This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/55:15 amSTL - SJO
1 stop18h 02mAmerican Airlines
Tue 5/136:03 amSJO - STL
2 stops14h 49mAmerican Airlines
Deal found 3/30$343
This Mytrip deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/276:10 pmSTL - SJO
3 stops41h 14mSpirit Airlines
Mon 5/512:55 amSJO - STL
1 stop15h 20mSpirit Airlines
Deal found 3/31$358
This Delta deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/15:45 amMCI - SJO
1 stop7h 14mDelta
Thu 6/121:25 pmSJO - MCI
1 stop9h 42mDelta
Deal found 3/30$368
This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/145:36 amMCI - SJO
1 stop8h 41mAmerican Airlines
Tue 10/2111:35 amSJO - MCI
2 stops20h 12mAmerican Airlines
Deal found 3/30$372
This United Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/55:20 amSTL - LIR
1 stop11h 05mUnited Airlines
Tue 5/133:25 pmLIR - STL
1 stop17h 31mUnited Airlines
Deal found 3/30$385
This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/276:20 pmSTL - LIR
1 stop18h 25mAmerican Airlines
Tue 6/312:45 pmLIR - STL
1 stop8h 34mAmerican Airlines
Deal found 3/30$394
This United Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/286:20 amMCI - SAL
1 stop6h 46mUnited Airlines
Mon 6/911:45 pmSAL - MCI
2 stops20h 38mUnited Airlines
Deal found 3/30$402
This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/85:09 amMCI - GUA
1 stop14h 21mAmerican Airlines
Tue 4/156:25 amGUA - MCI
1 stop15h 37mAmerican Airlines
Deal found 3/30$416
This Southwest deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/276:15 amSTL - SJO
1 stop6h 55mSouthwest
Tue 5/61:10 pmSJO - STL
1 stop8h 05mSouthwest
Deal found 3/31$422

Cheapflights Fare Finder

Customize your flight search to find flights from Missouri to Central America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 31, 2025.
Use the filters below to find and compare flights from Missouri to Central America that are best for you.

Fly from

Missouri

Fly to

Central America

Route

Depart

Return

Price

St. LouisSan José

STL - SJO

STLSJO

Lambert-St Louis

Tue 4/22

6:10 pm-11:18 am

1 stop18h 08m

San José Juan Santamaria Intl

Fri 4/25

11:35 am-12:04 am

1 stop11h 29m

$311

Kansas CitySan José

MCI - SJO

MCISJO

Kansas City

Sat 4/26

4:23 pm-11:18 am

2 stops19h 55m

San José Juan Santamaria Intl

Sat 5/10

11:32 am-9:30 pm

1 stop8h 58m

$312

St. LouisSan José

STL - SJO

STLSJO

Lambert-St Louis

Sun 6/1

6:00 am-11:59 am

1 stop6h 59m

San José Juan Santamaria Intl

Tue 6/10

1:25 pm-11:42 pm

1 stop9h 17m

$342

St. LouisSan José

STL - SJO

STLSJO

Lambert-St Louis

Mon 5/5

5:15 am-10:17 pm

1 stop18h 02m

San José Juan Santamaria Intl

Tue 5/13

6:03 am-9:52 pm

2 stops14h 49m

$343

St. LouisSan José

STL - SJO

STLSJO

Lambert-St Louis

Sun 4/27

6:10 pm-10:24 am

3 stops41h 14m

San José Juan Santamaria Intl

Mon 5/5

12:55 am-5:15 pm

1 stop15h 20m

$358

Kansas CitySan José

MCI - SJO

MCISJO

Kansas City

Sun 6/1

5:45 am-11:59 am

1 stop7h 14m

San José Juan Santamaria Intl

Thu 6/12

1:25 pm-12:07 am

1 stop9h 42m

$368

Kansas CitySan José

MCI - SJO

MCISJO

Kansas City

Sun 6/1

6:33 pm-1:09 pm

1 stop19h 36m

San José Juan Santamaria Intl

Wed 6/11

11:59 pm-8:51 am

1 stop7h 52m

$376

St. LouisLiberia

STL - LIR

STLLIR

Lambert-St Louis

Mon 5/5

5:20 am-3:25 pm

1 stop11h 05m

Liberia

Tue 5/13

3:25 pm-9:56 am

1 stop17h 31m

$385

St. LouisLiberia

STL - LIR

STLLIR

Lambert-St Louis

Tue 5/27

6:20 pm-11:45 am

1 stop18h 25m

Liberia

Tue 6/3

12:45 pm-10:19 pm

1 stop8h 34m

$394

Kansas CitySan Salvador

MCI - SAL

MCISAL

Kansas City

Mon 4/28

6:20 am-12:06 pm

1 stop6h 46m

San Salvador El Salvador Intl

Mon 6/9

11:45 pm-9:23 pm

2 stops20h 38m

$402

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/30

Showing 1-10 of 45 results
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Best time to book a flight from Missouri to Central America

Have a flexible travel schedule? Discover the best time to fly to Central America from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Central America

What is the cheapest month to book a flight from Missouri to Central America?

Currently, September is the cheapest month in which you can book a flight from Missouri to Central America (average of $398). Flying from Missouri to Central America in March is currently the most expensive (average of $555). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to CA?

Find hourly flight availability from Missouri to Central America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 31, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Missouri to Central America as you normally would.

Rainfall in Central America by month

Plan your trip to Central America by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Central America ranges from 0.0 - 13.0 inches per month. August is typically the wettest month, when rainfall can reach 13.0 in. February is typically the driest time to visit Central America when rainfall is around 0.0 in.

Temperature in Central America by month

Plan your trip to Central America by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Central America, use this chart to help with planning. For those seeking warmer temperatures, March is the ideal time of year to visit, when temperatures reach an average of 77.0 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 73.4 F).

Reviews of airlines servicing Central America

Get insights into the airlines that provide service to Central America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Central America. Reviews last updated March 31, 2025.
Alaska Airlines
8.0
Very good
9,818 reviews

Comfort

7.9

Crew

8.5

Entertainment

7.1

Boarding

8.2

Overall

8.0

Food

7.1

Reviews

1 / 20
10.0
Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them
Alaska Airlines
8.0
Very good
9,818 reviews
Alaska Airlines
8.0
Very good
9,818 reviews

Comfort

7.9

Crew

8.5

Entertainment

7.1

Boarding

8.2

Overall

8.0

Food

7.1

Reviews

1 / 20
10.0
Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them
Southwest
8.0
Very good
4,276 reviews
Alaska Airlines
8.0
Very good
9,818 reviews

Comfort

7.9

Crew

8.5

Entertainment

7.1

Boarding

8.2

Overall

8.0

Food

7.1

Reviews

1 / 20
10.0
Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them
Delta
8.0
Very good
7,899 reviews
Alaska Airlines
8.0
Very good
9,818 reviews

Comfort

7.9

Crew

8.5

Entertainment

7.1

Boarding

8.2

Overall

8.0

Food

7.1

Reviews

1 / 20
10.0
Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them
Copa Airlines
7.6
Good
1,400 reviews
Alaska Airlines
8.0
Very good
9,818 reviews

Comfort

7.9

Crew

8.5

Entertainment

7.1

Boarding

8.2

Overall

8.0

Food

7.1

Reviews

1 / 20
10.0
Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them
United Airlines
7.4
Good
8,614 reviews
Alaska Airlines
8.0
Very good
9,818 reviews

Comfort

7.9

Crew

8.5

Entertainment

7.1

Boarding

8.2

Overall

8.0

Food

7.1

Reviews

1 / 20
10.0
Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them

Related info for your journey

Find useful and relevant information for your journey from Missouri to Central America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Missouri to Central America one-way?

    To fly one-way, consider booking your trip with Spirit Airlines, which is currently one of the cheapest options available, starting at $128. American Airlines flights start at $155 while deals on Delta start at $175 one-way.

  • Can I find deals for flights from Missouri to Central America that include hotel bookings?

    Yes. In addition to deals on Missouri to Central America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Central America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Central America.

  • Can I find deals for business class flights from Missouri to Central America?

    Yes. Cheapflights offers flight deals from Missouri to Central America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Central America?

    Currently, September is the cheapest month in which you can book a flight from Missouri to Central America (average of $398). Flying from Missouri to Central America in March is currently the most expensive (average of $555). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Missouri to Central America

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Missouri to Central America

Discover the top 5 airlines that operate flights from Missouri to Central America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$242Average$421FlexibilityNo cancel feeOn-time65%
DeltaCheapest$250Average$589FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$309Average$621FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$330Average$643FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$418Average$621FlexibilityNo cancel feeOn-time63%
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