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Central America

$146+ Cheap flights from Mississippi to Central America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/28. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — SJO
Feb 27 — Mrz 61
Do 2/27
Do 3/6
1 adult, Economy
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Cheap flight deals from Mississippi to Central America

Keep the following information in mind while searching for Mississippi to Central America flight deals. Data was last updated Februar 22, 2025.

Round-trip from

$226
(eDestinos)

One-way from

$146
(Booking.com)
From Mississippi to Central America
Search Deals
One-way flight from Mississippi to Central America
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Find flight deals from Mississippi to Central America

Cheapest flights from Mississippi to Central America
Explore the most affordable flight options available from Mississippi to Central America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on Februar 22, 2025.

This eDestinos deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mo 3/248:56 amMEM - SJO
1 stop15h 54mSpirit Airlines
Mi 4/212:26 pmSJO - MEM
1 stop10h 33mSpirit Airlines
Deal found 2/22$226
This eDestinos deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sa 3/228:16 pmMEM - SAP
2 stops17h 37mSpirit Airlines
Sa 3/291:48 pmSAP - MEM
1 stop9h 11mSpirit Airlines
Deal found 2/20$283
This FlightHub deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mo 5/57:39 pmMEM - GUA
2 stops16h 55mSpirit Airlines
Mo 5/121:28 amGUA - MEM
1 stop13h 37mSpirit Airlines
Deal found 2/21$307
This Kiwi.com deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mo 4/78:16 pmMEM - SJO
1 stop15h 34mMultiple Airlines
Mo 4/148:46 amSJO - MEM
2 stops32h 10mMultiple Airlines
Deal found 2/21$313
This Kiwi.com deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Di 4/88:57 amMEM - SAL
2 stops15h 39mMultiple Airlines
Mo 4/1412:54 amSAL - MEM
1 stop16h 02mMultiple Airlines
Deal found 2/22$343
This American Airlines deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mo 9/155:42 amMEM - GUA
1 stop7h 52mAmerican Airlines
Mo 9/292:45 pmGUA - MEM
1 stop17h 02mAmerican Airlines
Deal found 2/21$431
This Mytrip deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sa 3/86:04 pmMEM - GUA
2 stops17h 37mMultiple Airlines
So 3/163:44 pmGUA - MEM
3 stops20h 36mMultiple Airlines
Deal found 2/20$438
This United Airlines deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 5/283:26 pmMEM - SAL
1 stop9h 32mUnited Airlines
Mi 6/113:30 pmSAL - MEM
1 stop16h 42mUnited Airlines
Deal found 2/21$440
This Kiwi.com deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Di 4/18:57 amMEM - PTY
1 stop11h 22mMultiple Airlines
Sa 4/512:03 pmPTY - MEM
1 stop11h 56mMultiple Airlines
Deal found 2/21$446
This Delta deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 3/136:00 amMEM - SAP
1 stop6h 00mDelta
Mi 3/2612:15 pmSAP - MEM
1 stop8h 01mDelta
Deal found 2/21$471
This Delta deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mo 5/57:05 amMEM - GUA
1 stop5h 36mDelta
Di 5/131:06 pmGUA - MEM
1 stop8h 45mDelta
Deal found 2/21$474
This American Airlines deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 3/135:11 amMEM - SAP
2 stops8h 45mAmerican Airlines
Mi 3/261:56 pmSAP - MEM
1 stop9h 00mAmerican Airlines
Deal found 2/21$476

Find flights from Mississippi to Central America within your budget

Customize your flight search to find flights from Mississippi to Central America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated Februar 22, 2025.

Fly from

Mississippi

Fly to

Central America

Route

Depart

Return

Price

MemphisSan José

MEM - SJO

MEMSJO

Memphis

Mo 3/24

8:56 am-11:50 pm

1 stop15h 54m

San José Juan Santamaria Intl

Mi 4/2

12:26 pm-11:59 pm

1 stop10h 33m

$226

MemphisSan Pedro Sula

MEM - SAP

MEMSAP

Memphis

Sa 3/22

8:16 pm-12:53 pm

2 stops17h 37m

San Pedro Sula Ramon Villeda

Sa 3/29

1:48 pm-11:59 pm

1 stop9h 11m

$283

MemphisGuatemala City

MEM - GUA

MEMGUA

Memphis

Mo 5/5

7:39 pm-11:34 am

2 stops16h 55m

Guatemala City La Aurora

Mo 5/12

1:28 am-4:05 pm

1 stop13h 37m

$307

MemphisSan José

MEM - SJO

MEMSJO

Memphis

Mo 4/7

8:16 pm-10:50 am

1 stop15h 34m

San José Juan Santamaria Intl

Mo 4/14

8:46 am-5:56 pm

2 stops32h 10m

$313

MemphisSan Salvador

MEM - SAL

MEMSAL

Memphis

Di 4/8

8:57 am-11:36 pm

2 stops15h 39m

San Salvador El Salvador Intl

Mo 4/14

12:54 am-5:56 pm

1 stop16h 02m

$343

MemphisGuatemala City

MEM - GUA

MEMGUA

Memphis

Sa 3/8

6:04 pm-11:41 am

2 stops17h 37m

Guatemala City La Aurora

So 3/16

3:44 pm-1:20 pm

3 stops20h 36m

$438

MemphisSan Salvador

MEM - SAL

MEMSAL

Memphis

Mi 5/28

3:26 pm-11:58 pm

1 stop9h 32m

San Salvador El Salvador Intl

Mi 6/11

3:30 pm-9:12 am

1 stop16h 42m

$440

MemphisPanama City

MEM - PTY

MEMPTY

Memphis

Di 4/1

8:57 am-8:19 pm

1 stop11h 22m

Panama City Tocumen Intl

Sa 4/5

12:03 pm-11:59 pm

1 stop11h 56m

$446

MemphisSan Pedro Sula

MEM - SAP

MEMSAP

Memphis

Do 3/13

6:00 am-11:00 am

1 stop6h 00m

San Pedro Sula Ramon Villeda

Mi 3/26

12:15 pm-9:16 pm

1 stop8h 01m

$471

MemphisGuatemala City

MEM - GUA

MEMGUA

Memphis

Mo 5/5

7:05 am-11:41 am

1 stop5h 36m

Guatemala City La Aurora

Di 5/13

1:06 pm-10:51 pm

1 stop8h 45m

$474

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/21

Showing 1-10 of 42 results
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Best time to book a flight from Mississippi to Central America

Have a flexible travel schedule? Discover the best time to fly to Central America from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Mississippi to Central America

Get recent, data-driven insights about flights from Mississippi to Central America including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Mississippi to Central America?

Currently, September is the cheapest month in which you can book a flight from Mississippi to Central America (average of $398). Flying from Mississippi to Central America in March is currently the most expensive (average of $555). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MS to CA?

Find hourly flight availability from Mississippi to Central America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated Februar 22, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Mississippi to Central America as you normally would.

Rainfall in Central America by month

Plan your trip to Central America by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Central America ranges from 0.0 - 13.0 inches per month. August is typically the wettest month, when rainfall can reach 13.0 in. February is typically the driest time to visit Central America when rainfall is around 0.0 in.

Temperature in Central America by month

Plan your trip to Central America by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Central America, use this chart to help with planning. For those seeking warmer temperatures, March is the ideal time of year to visit, when temperatures reach an average of 77.0 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 73.4 F).

Reviews of airlines servicing Central America

Get insights into the airlines that provide service to Central America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Central America. Reviews last updated Februar 22, 2025.
Southwest
8.1
Very good
4,395 reviews

Comfort

8.1

Entertainment

7.6

Overall

8.1

Crew

8.7

Boarding

8.2

Food

7.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Southwest
8.1
Very good
4,395 reviews
Southwest
8.1
Very good
4,395 reviews

Comfort

8.1

Entertainment

7.6

Overall

8.1

Crew

8.7

Boarding

8.2

Food

7.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Delta
8.0
Very good
8,203 reviews
Southwest
8.1
Very good
4,395 reviews

Comfort

8.1

Entertainment

7.6

Overall

8.1

Crew

8.7

Boarding

8.2

Food

7.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

United Airlines
7.4
Good
8,754 reviews
Southwest
8.1
Very good
4,395 reviews

Comfort

8.1

Entertainment

7.6

Overall

8.1

Crew

8.7

Boarding

8.2

Food

7.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

American Airlines
7.2
Good
10,000 reviews
Southwest
8.1
Very good
4,395 reviews

Comfort

8.1

Entertainment

7.6

Overall

8.1

Crew

8.7

Boarding

8.2

Food

7.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

WestJet
7.2
Good
2,800 reviews
Southwest
8.1
Very good
4,395 reviews

Comfort

8.1

Entertainment

7.6

Overall

8.1

Crew

8.7

Boarding

8.2

Food

7.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Related info for your journey

Find useful and relevant information for your journey from Mississippi to Central America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Mississippi to Central America one-way?

    To fly one-way, consider booking your trip with Spirit Airlines, which is currently one of the cheapest options available, starting at $146. Delta flights start at $197 while deals on American Airlines start at $203 one-way.

  • Can I find deals for flights from Mississippi to Central America that include hotel bookings?

    Yes. In addition to deals on Mississippi to Central America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to Central America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to Central America.

  • Can I find deals for business class flights from Mississippi to Central America?

    Yes. Cheapflights offers flight deals from Mississippi to Central America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mississippi to Central America?

    Currently, September is the cheapest month in which you can book a flight from Mississippi to Central America (average of $398). Flying from Mississippi to Central America in March is currently the most expensive (average of $555). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Mississippi to Central America

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Mississippi to Central America

Discover the top 3 airlines that operate flights from Mississippi to Central America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated Februar 22, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$338Average$613FlexibilityNo cancel feeOn-time71%
DeltaCheapest$364Average$635FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$413Average$649FlexibilityNo cancel feeOn-time69%
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