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Central America

$119+ Cheap flights from Mississippi to Central America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/14. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — SJO
Apr 7 — Apr 141
Mon 4/7
Mon 4/14
1 adult, Economy
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Cheap flight deals from Mississippi to Central America

Keep the following information in mind while searching for Mississippi to Central America flight deals. Data was last updated April 2, 2025.

Round-trip from

$353
(Mytrip)

One-way from

$119
(Kiwi.com)
From Mississippi to Central America
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One-way flight from Mississippi to Central America
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Find flight deals from Mississippi to Central America

Cheapest flights from Mississippi to Central America
Explore the most affordable flight options available from Mississippi to Central America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 2, 2025.

This Mytrip deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/57:39 pmMEM - SAP
2 stops18h 21mSpirit Airlines
Sat 5/101:50 pmSAP - MEM
1 stop26h 39mSpirit Airlines
Deal found 4/1$353
This Mytrip deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/175:14 pmMEM - GUA
2 stops19h 19mMultiple Airlines
Sat 5/2412:33 pmGUA - MEM
1 stop18h 29mMultiple Airlines
Deal found 4/1$358
This United Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/136:00 amMEM - SAL
1 stop7h 06mUnited Airlines
Thu 5/226:00 amSAL - MEM
1 stop6h 56mUnited Airlines
Deal found 4/1$381
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/125:20 pmMEM - SAL
2 stops19h 49mAmerican Airlines
Thu 5/221:12 pmSAL - MEM
1 stop9h 45mAmerican Airlines
Deal found 4/1$385
This Cheapflightsfares deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/86:34 pmMEM - GUA
1 stop6h 20mSpirit Airlines
Wed 6/1812:50 amGUA - MEM
1 stop14h 54mSpirit Airlines
Deal found 4/1$389
This American Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/273:36 pmJAN - PTY
2 stops20h 39mAmerican Airlines
Wed 5/211:20 pmPTY - JAN
2 stops20h 21mAmerican Airlines
Deal found 4/2$392
This United Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/272:00 pmJAN - PTY
1 stop24h 14mUnited Airlines
Wed 5/217:55 amPTY - JAN
1 stop8h 10mUnited Airlines
Deal found 4/2$394
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/36:58 pmMEM - LIR
1 stop17h 22mAmerican Airlines
Fri 5/162:26 pmLIR - MEM
1 stop8h 31mAmerican Airlines
Deal found 4/1$405
This Kiwi.com deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/246:51 pmMEM - SAP
1 stop19h 09mMultiple Airlines
Tue 4/291:50 pmSAP - MEM
2 stops27h 52mMultiple Airlines
Deal found 4/1$405
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/275:01 pmMEM - BZE
2 stops18h 14mAmerican Airlines
Mon 10/133:08 pmBZE - MEM
1 stop16h 35mAmerican Airlines
Deal found 4/1$419
This United deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/226:30 amMEM - PTY
1 stop7h 44mUnited Airlines
Tue 4/297:55 amPTY - MEM
1 stop14h 20mUnited Airlines
Deal found 4/1$437
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/15:00 pmMEM - SAP
2 stops20h 56mAmerican Airlines
Tue 4/81:25 pmSAP - MEM
2 stops22h 27mAmerican Airlines
Deal found 4/1$442

Cheapflights Fare Finder

Customize your flight search to find flights from Mississippi to Central America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 2, 2025.
Use the filters below to find and compare flights from Mississippi to Central America that are best for you.

Fly from

Mississippi

Fly to

Central America

Route

Depart

Return

Price

MemphisSan Pedro Sula

MEM - SAP

MEMSAP

Memphis

Mon 5/5

7:39 pm-1:00 pm

2 stops18h 21m

San Pedro Sula Ramon Villeda

Sat 5/10

1:50 pm-5:29 pm

1 stop26h 39m

$353

MemphisGuatemala City

MEM - GUA

MEMGUA

Memphis

Sat 5/17

5:14 pm-11:33 am

2 stops19h 19m

Guatemala City La Aurora

Sat 5/24

12:33 pm-8:02 am

1 stop18h 29m

$358

MemphisSan Salvador

MEM - SAL

MEMSAL

Memphis

Tue 5/13

6:00 am-12:06 pm

1 stop7h 06m

San Salvador El Salvador Intl

Thu 5/22

6:00 am-1:56 pm

1 stop6h 56m

$381

MemphisSan Salvador

MEM - SAL

MEMSAL

Memphis

Mon 5/12

5:20 pm-12:09 pm

2 stops19h 49m

San Salvador El Salvador Intl

Thu 5/22

1:12 pm-8:40 am

2 stops18h 28m

$385

MemphisGuatemala City

MEM - GUA

MEMGUA

Memphis

Sun 6/8

6:34 pm-11:54 pm

1 stop6h 20m

Guatemala City La Aurora

Wed 6/18

12:50 am-4:44 pm

1 stop14h 54m

$389

JacksonPanama City

JAN - PTY

JANPTY

Jackson-Evers Intl

Sun 4/27

3:36 pm-12:15 pm

2 stops20h 39m

Panama City Tocumen Intl

Wed 5/21

1:20 pm-9:41 am

2 stops20h 21m

$392

JacksonPanama City

JAN - PTY

JANPTY

Jackson-Evers Intl

Sun 4/27

2:00 pm-2:14 pm

1 stop24h 14m

Panama City Tocumen Intl

Wed 5/21

7:55 am-4:05 pm

1 stop8h 10m

$394

MemphisSan Pedro Sula

MEM - SAP

MEMSAP

Memphis

Thu 4/24

6:51 pm-1:00 pm

1 stop19h 09m

San Pedro Sula Ramon Villeda

Tue 4/29

1:50 pm-6:42 pm

2 stops27h 52m

$405

MemphisLiberia

MEM - LIR

MEMLIR

Memphis

Sat 5/3

6:58 pm-11:20 am

1 stop17h 22m

Liberia

Fri 5/16

2:26 pm-11:57 pm

1 stop8h 31m

$405

MemphisBelize City

MEM - BZE

MEMBZE

Memphis

Sat 9/27

5:01 pm-10:15 am

2 stops18h 14m

Belize City Philip S.W.Goldson

Mon 10/13

3:08 pm-8:43 am

1 stop16h 35m

$419

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/1

Showing 1-10 of 46 results
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Best time to book a flight from Mississippi to Central America

Have a flexible travel schedule? Discover the best time to fly to Central America from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to Central America

What is the cheapest month to book a flight from Mississippi to Central America?

Currently, September is the cheapest month in which you can book a flight from Mississippi to Central America (average of $398). Flying from Mississippi to Central America in March is currently the most expensive (average of $555). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MS to CA?

Find hourly flight availability from Mississippi to Central America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 2, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Mississippi to Central America as you normally would.

Rainfall in Central America by month

Plan your trip to Central America by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Central America ranges from 0.0 - 13.0 inches per month. August is typically the wettest month, when rainfall can reach 13.0 in. February is typically the driest time to visit Central America when rainfall is around 0.0 in.

Temperature in Central America by month

Plan your trip to Central America by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Central America, use this chart to help with planning. For those seeking warmer temperatures, March is the ideal time of year to visit, when temperatures reach an average of 77.0 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 73.4 F).

Reviews of airlines servicing Central America

Get insights into the airlines that provide service to Central America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Central America. Reviews last updated April 2, 2025.
Delta
8.0
Very good
7,899 reviews

Crew

8.5

Entertainment

7.9

Boarding

8.2

Food

7.3

Comfort

8.0

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,899 reviews
Delta
8.0
Very good
7,899 reviews

Crew

8.5

Entertainment

7.9

Boarding

8.2

Food

7.3

Comfort

8.0

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
United Airlines
7.4
Good
8,615 reviews
Delta
8.0
Very good
7,899 reviews

Crew

8.5

Entertainment

7.9

Boarding

8.2

Food

7.3

Comfort

8.0

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,899 reviews

Crew

8.5

Entertainment

7.9

Boarding

8.2

Food

7.3

Comfort

8.0

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
WestJet
7.2
Good
2,789 reviews
Delta
8.0
Very good
7,899 reviews

Crew

8.5

Entertainment

7.9

Boarding

8.2

Food

7.3

Comfort

8.0

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Spirit Airlines
6.3
Okay
7,886 reviews
Delta
8.0
Very good
7,899 reviews

Crew

8.5

Entertainment

7.9

Boarding

8.2

Food

7.3

Comfort

8.0

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Mississippi to Central America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Mississippi to Central America one-way?

    To fly one-way, consider booking your trip with Spirit Airlines, which is currently one of the cheapest options available, starting at $119. United Airlines flights start at $179 while deals on American Airlines start at $185 one-way.

  • Can I find deals for flights from Mississippi to Central America that include hotel bookings?

    Yes. In addition to deals on Mississippi to Central America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to Central America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to Central America.

  • Can I find deals for business class flights from Mississippi to Central America?

    Yes. Cheapflights offers flight deals from Mississippi to Central America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mississippi to Central America?

    Currently, September is the cheapest month in which you can book a flight from Mississippi to Central America (average of $398). Flying from Mississippi to Central America in March is currently the most expensive (average of $555). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Mississippi to Central America

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Top 3 airlines flying from Mississippi to Central America

Discover the top 3 airlines that operate flights from Mississippi to Central America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 2, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$372Average$735FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$384Average$650FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$467Average$597FlexibilityNo cancel feeOn-time71%

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