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Central America

$204+ Cheap flights from Knoxville (TYS) to Central America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/27. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — SJO
Feb 3 — Feb 101
Mon 2/3
Mon 2/10
1 adult, Economy
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Cheap flight deals from Knoxville to Central America

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Central America (0CA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 29, 2025.

Round-trip from

$346
(Kiwi.com)

One-way from

$210
(Delta)
From Knoxville McGhee Tyson to Central America
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One-way flight from Knoxville McGhee Tyson to Central America
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Find flight deals from Knoxville to Central America

Cheapest flights from Knoxville to Central America
Explore the most affordable flight options available from Knoxville to Central America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2025.

This Kiwi.com deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/52:51 pmTYS - SJO
1 stop10h 59mMultiple Airlines
Tue 3/1812:50 amSJO - TYS
1 stop11h 11mMultiple Airlines
Deal found 1/29$346
This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/129:00 amTYS - GUA
1 stop16h 58mMultiple Airlines
Tue 3/1812:53 amGUA - TYS
1 stop11h 08mMultiple Airlines
Deal found 1/28$396
This American Airlines deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/256:53 amTYS - MGA
1 stop14h 56mAmerican Airlines
Wed 4/26:14 amMGA - TYS
1 stop14h 40mAmerican Airlines
Deal found 1/29$460
This American Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/307:55 pmTYS - RTB
2 stops18h 50mAmerican Airlines
Sat 6/71:38 pmRTB - TYS
2 stops18h 41mAmerican Airlines
Deal found 1/28$477
This Mytrip deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/277:13 pmTYS - MGA
2 stops19h 32mMultiple Airlines
Mon 3/311:40 pmMGA - TYS
2 stops26h 00mMultiple Airlines
Deal found 1/29$489
This American Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/253:54 pmTYS - SAL
1 stop22h 51mAmerican Airlines
Tue 3/186:00 amSAL - TYS
1 stop14h 54mAmerican Airlines
Deal found 1/28$489
This American Airlines deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/68:41 pmTYS - LIR
2 stops18h 19mAmerican Airlines
Sat 7/121:00 pmLIR - TYS
2 stops19h 24mAmerican Airlines
Deal found 1/29$496
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/94:59 pmTYS - PTY
1 stop24h 13mUnited Airlines
Sun 4/133:20 pmPTY - TYS
1 stop27h 46mUnited Airlines
Deal found 1/27$506
This American Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/36:55 amTYS - PTY
1 stop6h 35mAmerican Airlines
Mon 3/311:05 pmPTY - TYS
1 stop8h 49mAmerican Airlines
Deal found 1/28$507
This American Airlines deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/67:54 pmTYS - BZE
2 stops17h 21mAmerican Airlines
Sun 4/133:15 pmBZE - TYS
2 stops17h 22mAmerican Airlines
Deal found 1/29$522
This United Airlines deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/307:00 amTYS - RTB
1 stop6h 28mUnited Airlines
Mon 6/912:30 pmRTB - TYS
1 stop8h 49mUnited Airlines
Deal found 1/29$528
This American Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/227:17 amTYS - GUA
2 stops13h 13mAmerican Airlines
Tue 4/2912:40 pmGUA - TYS
1 stop8h 50mAmerican Airlines
Deal found 1/28$528

Find flights from Knoxville to Central America within your budget

Customize your flight search to find flights from Knoxville to Central America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2025.

Fly from

Any airport

Fly to

Any airport

Route

Depart

Return

Price

KnoxvilleSan José

TYS - SJO

TYSSJO

Knoxville McGhee Tyson

Wed 3/5

2:51 pm-12:50 am

1 stop10h 59m

San José Juan Santamaria Intl

Tue 3/18

12:50 am-2:01 pm

1 stop11h 11m

$346

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Wed 3/12

9:00 am-11:58 pm

1 stop16h 58m

Guatemala City La Aurora

Tue 3/18

12:53 am-2:01 pm

1 stop11h 08m

$396

KnoxvilleManagua

TYS - MGA

TYSMGA

Knoxville McGhee Tyson

Tue 3/25

6:53 am-7:49 pm

1 stop14h 56m

Managua Augusto C Sandino

Wed 4/2

6:14 am-10:54 pm

1 stop14h 40m

$460

KnoxvilleCoxen Hole

TYS - RTB

TYSRTB

Knoxville McGhee Tyson

Fri 5/30

7:55 pm-12:45 pm

2 stops18h 50m

Coxen Hole Roatan

Sat 6/7

1:38 pm-10:19 am

2 stops18h 41m

$477

KnoxvilleManagua

TYS - MGA

TYSMGA

Knoxville McGhee Tyson

Thu 3/27

7:13 pm-12:45 pm

2 stops19h 32m

Managua Augusto C Sandino

Mon 3/31

1:40 pm-5:40 pm

2 stops26h 00m

$489

KnoxvilleSan Salvador

TYS - SAL

TYSSAL

Knoxville McGhee Tyson

Tue 2/25

3:54 pm-1:45 pm

1 stop22h 51m

San Salvador El Salvador Intl

Tue 3/18

6:00 am-10:54 pm

1 stop14h 54m

$489

KnoxvilleLiberia

TYS - LIR

TYSLIR

Knoxville McGhee Tyson

Sun 7/6

8:41 pm-1:00 pm

2 stops18h 19m

Liberia

Sat 7/12

1:00 pm-10:24 am

2 stops19h 24m

$496

KnoxvillePanama City

TYS - PTY

TYSPTY

Knoxville McGhee Tyson

Wed 4/9

4:59 pm-4:12 pm

1 stop24h 13m

Panama City Tocumen Intl

Sun 4/13

3:20 pm-8:06 pm

1 stop27h 46m

$506

KnoxvillePanama City

TYS - PTY

TYSPTY

Knoxville McGhee Tyson

Mon 3/3

6:55 am-1:30 pm

1 stop6h 35m

Panama City Tocumen Intl

Mon 3/31

1:05 pm-10:54 pm

1 stop8h 49m

$507

KnoxvilleBelize City

TYS - BZE

TYSBZE

Knoxville McGhee Tyson

Sun 4/6

7:54 pm-11:15 am

2 stops17h 21m

Belize City Philip S.W.Goldson

Sun 4/13

3:15 pm-10:37 am

2 stops17h 22m

$522

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/29

Showing 1-10 of 36 results
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Best time to book a flight from Knoxville to Central America

Have a flexible travel schedule? Discover the best time to fly to Central America from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Knoxville to Central America

Get recent, data-driven insights about flights from Knoxville to Central America including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Knoxville to Central America?

Currently, September is the cheapest month in which you can book a flight from Knoxville to Central America (average of $398). Flying from Knoxville to Central America in March is currently the most expensive (average of $555). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to CA?

Find hourly flight availability from Knoxville to Central America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 29, 2025.

When flying from Knoxville to Central America, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Central America by month

Plan your trip to Central America by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Central America ranges from 0.0 - 13.0 inches per month. August is typically the wettest month, when rainfall can reach 13.0 in. February is typically the driest time to visit Central America when rainfall is around 0.0 in.

Temperature in Central America by month

Plan your trip to Central America by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Central America, use this chart to help with planning. For those seeking warmer temperatures, March is the ideal time of year to visit, when temperatures reach an average of 77.0 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 73.4 F).

Reviews of airlines servicing Central America

Get insights into the airlines that provide service to Central America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Central America. Reviews last updated January 29, 2025.
Delta
8.0
Very good
8,456 reviews

Comfort

8.0

Entertainment

7.9

Food

7.3

Boarding

8.2

Overall

8.0

Crew

8.5

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Delta
8.0
Very good
8,456 reviews
Delta
8.0
Very good
8,456 reviews

Comfort

8.0

Entertainment

7.9

Food

7.3

Boarding

8.2

Overall

8.0

Crew

8.5

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

United Airlines
7.4
Good
8,916 reviews
Delta
8.0
Very good
8,456 reviews

Comfort

8.0

Entertainment

7.9

Food

7.3

Boarding

8.2

Overall

8.0

Crew

8.5

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
8,456 reviews

Comfort

8.0

Entertainment

7.9

Food

7.3

Boarding

8.2

Overall

8.0

Crew

8.5

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Air Canada
7.0
Good
8,638 reviews
Delta
8.0
Very good
8,456 reviews

Comfort

8.0

Entertainment

7.9

Food

7.3

Boarding

8.2

Overall

8.0

Crew

8.5

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Avianca
6.9
Okay
2,542 reviews
Delta
8.0
Very good
8,456 reviews

Comfort

8.0

Entertainment

7.9

Food

7.3

Boarding

8.2

Overall

8.0

Crew

8.5

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Central America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Central America?

    Knoxville McGhee Tyson (TYS) is the airport you will fly out of if you book a flight from Knoxville to Central America. It is only a 11.3 mi journey to McGhee Tyson (TYS) from Knoxville’s city center.

  • What are the cheapest airlines to fly from Knoxville to Central America one-way?

    To fly one-way, consider booking your trip with Delta, which is currently one of the cheapest options available, starting at $210. American Airlines flights start at $220 while deals on United Airlines start at $275 one-way.

  • What are the most popular routes from Knoxville to Central America?

    While some choose either Knoxville McGhee Tyson - Liberia or Knoxville McGhee Tyson - Panama City Tocumen Intl, Knoxville McGhee Tyson - San José Juan Santamaria Intl is the most popular route from Knoxville to Central America.

  • Can I find deals for flights from Knoxville to Central America that include hotel bookings?

    Yes. In addition to deals on Knoxville to Central America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Central America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Central America.

  • Can I find deals for business class flights from Knoxville to Central America?

    Yes. Cheapflights offers flight deals from Knoxville to Central America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Central America?

    Currently, September is the cheapest month in which you can book a flight from Knoxville to Central America (average of $398). Flying from Knoxville to Central America in March is currently the most expensive (average of $555). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Top 3 airlines flying from Knoxville to Central America

Discover the top 3 airlines that operate flights from Knoxville to Central America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$281Average$628FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$388Average$657FlexibilityNo cancel feeOn-time71%
DeltaCheapest$390Average$602FlexibilityNo cancel feeOn-timeN/A
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