HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Central America

$222+ Cheap flights from Knoxville (TYS) to Central America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/8. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — SJO
Dec 28 — Jan 41
Sat 12/28
Sat 1/4
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Knoxville to Central America with Cheapflights

1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”
2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.
3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Knoxville to Central America

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Central America (0CA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 23, 2024.

Round-trip from

$419
(American Airlines)

One-way from

$222
(American Airlines)
From Knoxville McGhee Tyson to Central America
Search Deals
One-way flight from Knoxville McGhee Tyson to Central America
Search Deals

Find flight deals from Knoxville to Central America

Cheapest flights from Knoxville to Central America
Explore the most affordable flight options available from Knoxville to Central America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 23, 2024.

This United Airlines deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/249:10 amTYS - PTY
1 stop10h 28mUnited Airlines
Tue 12/318:55 amPTY - TYS
1 stop11h 05mUnited Airlines
Deal found 12/22$508
This American Airlines deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/2410:58 amTYS - PTY
2 stops26h 22mAmerican Airlines
Tue 12/312:40 pmPTY - TYS
1 stop9h 32mAmerican Airlines
Deal found 12/22$609
This Delta deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/236:25 amTYS - BZE
1 stop6h 58mDelta
Fri 12/271:38 pmBZE - TYS
1 stop7h 33mDelta
Deal found 12/22$711
This United Airlines deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/249:10 amTYS - BZE
1 stop6h 18mUnited Airlines
Tue 12/313:00 pmBZE - TYS
1 stop28h 48mUnited Airlines
Deal found 12/22$791
This American Airlines deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/246:00 amTYS - BZE
1 stop7h 21mAmerican Airlines
Tue 12/314:30 pmBZE - TYS
2 stops20h 36mAmerican Airlines
Deal found 12/22$805
This Kiwi.com deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/285:55 pmTYS - PTY
2 stops22h 53mMultiple Airlines
Tue 12/3112:03 pmPTY - TYS
1 stop9h 23mMultiple Airlines
Deal found 12/22$1,030
This Delta deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/256:25 amTYS - PTY
1 stop7h 30mDelta
Sat 12/288:10 amPTY - TYS
1 stop10h 02mDelta
Deal found 12/22$1,341
This United deal was found by Cheapflights users on 12/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/284:55 pmTYS - LIR
1 stop26h 02mUnited Airlines
Sat 1/44:00 pmLIR - TYS
1 stop21h 00mUnited Airlines
Deal found 12/23$1,643
This Mytrip deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/258:15 amTYS - BZE
3 stops29h 05mMultiple Airlines
Sat 12/284:20 pmBZE - TYS
2 stops30h 11mMultiple Airlines
Deal found 12/22$1,666
This American Airlines deal was found by Cheapflights users on 12/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/284:07 pmTYS - LIR
2 stops19h 34mAmerican Airlines
Sat 1/43:30 pmLIR - TYS
2 stops17h 37mAmerican Airlines
Deal found 12/23$1,929
This United Airlines deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/222:45 pmTYS - SAL
1 stop27h 01mUnited Airlines
Sun 12/291:10 amSAL - TYS
1 stop12h 33mUnited Airlines
Deal found 12/22$2,060
This Kiwi.com deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/259:50 amTYS - PTY
1 stop10h 44mCopa Airlines
Mon 12/309:13 amPTY - TYS
1 stop10h 09mCopa Airlines
Deal found 12/22$2,289

Find flights from Knoxville to Central America within your budget

Customize your flight search to find flights from Knoxville to Central America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 23, 2024.

Fly from

Any airport

Fly to

Any airport

Route

Depart

Return

Price

KnoxvilleSan José

TYS - SJO

TYSSJO

Knoxville McGhee Tyson

Thu 2/27

9:16 pm-12:20 pm

1 stop16h 04m

San José Juan Santamaria Intl

Tue 3/4

1:25 pm-2:01 pm

1 stop23h 36m

$367

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Tue 4/15

6:55 am-1:45 pm

1 stop8h 50m

Guatemala City La Aurora

Tue 4/29

2:55 pm-11:30 pm

1 stop6h 35m

$419

KnoxvilleBelize City

TYS - BZE

TYSBZE

Knoxville McGhee Tyson

Tue 4/1

5:45 am-11:07 am

1 stop7h 22m

Belize City Philip S.W.Goldson

Wed 4/9

12:30 pm-11:43 pm

1 stop9h 13m

$442

KnoxvilleCoxen Hole

TYS - RTB

TYSRTB

Knoxville McGhee Tyson

Sat 5/31

6:03 pm-12:25 pm

2 stops20h 22m

Coxen Hole Roatan

Sat 6/7

1:38 pm-10:19 am

2 stops18h 41m

$445

KnoxvilleBelize City

TYS - BZE

TYSBZE

Knoxville McGhee Tyson

Tue 4/1

5:53 pm-11:15 am

2 stops19h 22m

Belize City Philip S.W.Goldson

Wed 4/9

3:15 pm-10:05 am

2 stops16h 50m

$446

KnoxvillePanama City

TYS - PTY

TYSPTY

Knoxville McGhee Tyson

Mon 1/20

6:45 am-2:45 pm

1 stop8h 00m

Panama City Tocumen Intl

Mon 3/17

7:55 am-11:30 pm

1 stop14h 35m

$456

KnoxvilleSan Salvador

TYS - SAL

TYSSAL

Knoxville McGhee Tyson

Sun 3/9

6:53 am-7:05 pm

1 stop14h 12m

San Salvador El Salvador Intl

Fri 3/14

6:00 am-10:54 pm

1 stop14h 54m

$468

KnoxvilleLiberia

TYS - LIR

TYSLIR

Knoxville McGhee Tyson

Mon 6/16

6:22 pm-11:20 am

2 stops18h 58m

Liberia

Mon 6/23

2:25 pm-12:08 pm

2 stops19h 43m

$485

KnoxvilleManagua

TYS - MGA

TYSMGA

Knoxville McGhee Tyson

Mon 5/26

8:28 pm-10:50 am

2 stops16h 22m

Managua Augusto C Sandino

Mon 6/9

1:10 pm-10:19 am

2 stops19h 09m

$493

KnoxvillePanama City

TYS - PTY

TYSPTY

Knoxville McGhee Tyson

Mon 1/20

8:05 pm-3:49 pm

2 stops19h 44m

Panama City Tocumen Intl

Tue 3/18

1:05 pm-10:54 pm

1 stop8h 49m

$497

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/23

Showing 1-10 of 29 results
1
2
3

Best time to book a flight from Knoxville to Central America

Have a flexible travel schedule? Discover the best time to fly to Central America from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Knoxville to Central America

Get recent, data-driven insights about flights from Knoxville to Central America including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Knoxville to Central America?

Currently, September is the cheapest month in which you can book a flight from Knoxville to Central America (average of $398). Flying from Knoxville to Central America in March is currently the most expensive (average of $555). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to CA?

Find hourly flight availability from Knoxville to Central America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 23, 2024.

When flying from Knoxville to Central America, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Central America by month

Plan your trip to Central America by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Central America ranges from 0.0 - 13.0 inches per month. August is typically the wettest month, when rainfall can reach 13.0 in. February is typically the driest time to visit Central America when rainfall is around 0.0 in.

Temperature in Central America by month

Plan your trip to Central America by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Central America, use this chart to help with planning. For those seeking warmer temperatures, March is the ideal time of year to visit, when temperatures reach an average of 77.0 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 73.4 F).

Reviews of airlines servicing Central America

Get insights into the airlines that provide service to Central America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Central America. Reviews last updated December 23, 2024.
Delta
8.0
Very good
8,588 reviews

Boarding

8.2

Comfort

8.0

Crew

8.6

Food

7.3

Entertainment

7.9

Overall

8.0

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Delta
8.0
Very good
8,588 reviews
Delta
8.0
Very good
8,588 reviews

Boarding

8.2

Comfort

8.0

Crew

8.6

Food

7.3

Entertainment

7.9

Overall

8.0

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Copa Airlines
7.7
Good
1,710 reviews
Delta
8.0
Very good
8,588 reviews

Boarding

8.2

Comfort

8.0

Crew

8.6

Food

7.3

Entertainment

7.9

Overall

8.0

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

United Airlines
7.4
Good
9,022 reviews
Delta
8.0
Very good
8,588 reviews

Boarding

8.2

Comfort

8.0

Crew

8.6

Food

7.3

Entertainment

7.9

Overall

8.0

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
8,588 reviews

Boarding

8.2

Comfort

8.0

Crew

8.6

Food

7.3

Entertainment

7.9

Overall

8.0

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Avianca
7.0
Good
2,651 reviews
Delta
8.0
Very good
8,588 reviews

Boarding

8.2

Comfort

8.0

Crew

8.6

Food

7.3

Entertainment

7.9

Overall

8.0

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Central America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Central America?

    Knoxville McGhee Tyson (TYS) is the airport you will fly out of if you book a flight from Knoxville to Central America. It is only a 11.3 mi journey to McGhee Tyson (TYS) from Knoxville’s city center.

  • What are the cheapest airlines to fly from Knoxville to Central America one-way?

    To fly one-way, consider booking your trip with American Airlines, which is currently one of the cheapest options available, starting at $222. Copa Airlines flights start at $365 while deals on United Airlines start at $958 one-way.

  • What are the most popular routes from Knoxville to Central America?

    While some choose either Knoxville McGhee Tyson - San José Juan Santamaria Intl or Knoxville McGhee Tyson - Belize City Philip S.W.Goldson, Knoxville McGhee Tyson - Liberia is the most popular route from Knoxville to Central America.

  • Can I find deals for flights from Knoxville to Central America that include hotel bookings?

    Yes. In addition to deals on Knoxville to Central America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Central America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Central America.

  • Can I find deals for business class flights from Knoxville to Central America?

    Yes. Cheapflights offers flight deals from Knoxville to Central America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Central America?

    Currently, September is the cheapest month in which you can book a flight from Knoxville to Central America (average of $398). Flying from Knoxville to Central America in March is currently the most expensive (average of $555). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Knoxville to Central America

See prices for flight routes from nearby airports that may be better suited for you.
Nashville to Los Angeles flights
Nashville to LaGuardia flights
Nashville to John F Kennedy Intl flights
Nashville to Newark flights
Nashville to Orlando flights
Nashville to Denver flights
Nashville to Miami flights
Nashville to Seattle flights
Nashville to Salt Lake City flights
Nashville to O'Hare Intl flights
Memphis to Las Vegas flights
Nashville to Las Vegas flights
Nashville to Fort Lauderdale flights
Nashville to Hobby flights
Nashville to San Francisco flights
Nashville to Cancún flights
Memphis to Los Angeles flights
Nashville to Heathrow flights
Nashville to Dallas/Fort Worth flights
Memphis to Denver flights
Nashville to Ontario flights
Nashville to Boston flights
Nashville to Burbank flights
Memphis to LaGuardia flights
Memphis to Miami flights
Memphis to Orlando flights
Nashville to Honolulu flights
Nashville to George Bush Intcntl flights
Knoxville to Los Angeles flights
Nashville to Sky Harbor Intl flights
Memphis to John F Kennedy Intl flights
Nashville to Reagan-National flights
Nashville to Tampa flights
Memphis to Hobby flights
Memphis to Salt Lake City flights
Nashville to Luis Munoz Marin Intl flights
Chattanooga to LaGuardia flights
Memphis to Newark flights
Memphis to Cancún flights
Chattanooga to John F Kennedy Intl flights
Memphis to Dallas/Fort Worth flights
Nashville to Vancouver Intl flights
Nashville to Cozumel flights
Nashville to Portland flights
Nashville to San Diego flights
Memphis to Atlanta flights
Knoxville to Las Vegas flights
Knoxville to Orlando Sanford Intl flights
Memphis to O'Hare Intl flights
Nashville to Santa Ana flights

Top 3 airlines flying from Knoxville to Central America

Discover the top 3 airlines that operate flights from Knoxville to Central America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 23, 2024.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$281Average$608FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$299Average$639FlexibilityNo cancel feeOn-time71%
DeltaCheapest$390Average$644FlexibilityNo cancel feeOn-timeN/A
100% Free
Cheapflights is completely free to use, so you can start saving the moment you arrive.
Book with Flexibility
Our users can plan ahead with confidence and find flights with no change fees
Travel Smart
Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.