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Central America

$170+ Cheap flights from Des Moines (DSM) to Central America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/28. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — SJO
Apr 22 — Apr 291
Tue 4/22
Tue 4/29
1 adult, Economy
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Cheap flight deals from Des Moines to Central America

Keep the following information in mind while searching for Des Moines to Central America flight deals. Data was last updated April 17, 2025.

Most accurate provider

AranGrant
3 stars

Most trusted provider

AranGrant
3 stars

Round-trip from

$347
(Mytrip)

One-way from

$170
(Kiwi.com)

Popular in

December

Cheapest in

September

Average price

$670
Provider with most accurate pricing for Des Moines-San Salvador El Salvador Intl flight deals.
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Provider most trusted by Cheapflights users for Des Moines-San Salvador El Salvador Intl flights.
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From Des Moines to Central America
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One-way flight from Des Moines to Central America
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Highest demand for flights based on searches. 20% potential increase in price ($186 potential increase over avg. RT price).
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Cheapest flight prices on average. 8% potential price decrease ($58 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from Des Moines to Central America

Cheapest flights from Des Moines to Central America
Explore the most affordable flight options available from Des Moines to Central America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 17, 2025.

This Mytrip deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/168:30 amDSM - SJO
1 stop28h 03mMultiple Airlines
Sun 5/1812:28 pmSJO - DSM
1 stop26h 25mMultiple Airlines
Deal found 4/16$347
This Mytrip deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/312:54 pmDSM - GUA
2 stops21h 39mMultiple Airlines
Thu 6/512:59 amGUA - DSM
1 stop11h 56mMultiple Airlines
Deal found 4/16$387
This Kissandfly.com deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kissandfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/315:30 pmDSM - PTY
2 stops19h 18mKLM
Sat 6/72:13 pmPTY - DSM
2 stops19h 25mKLM
Deal found 4/16$428
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/315:35 amDSM - PTY
1 stop7h 13mDelta
Sat 6/72:13 pmPTY - DSM
1 stop8h 17mDelta
Deal found 4/16$441
This United Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/176:45 pmDSM - SAL
2 stops20h 38mUnited Airlines
Sat 5/241:25 pmSAL - DSM
2 stops20h 02mUnited Airlines
Deal found 4/17$458
This United Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/246:45 pmDSM - PTY
2 stops21h 27mUnited Airlines
Sat 5/313:20 pmPTY - DSM
2 stops30h 02mUnited Airlines
Deal found 4/16$461
This American Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/245:00 amDSM - SAL
2 stops15h 56mAmerican Airlines
Thu 8/211:10 pmSAL - DSM
2 stops18h 53mAmerican Airlines
Deal found 4/16$469
This American Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/314:04 pmDSM - PTY
2 stops20h 15mAmerican Airlines
Sat 6/73:20 pmPTY - DSM
2 stops17h 47mAmerican Airlines
Deal found 4/16$489
This American Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/15:26 amDSM - GUA
1 stop12h 33mAmerican Airlines
Mon 9/88:25 amGUA - DSM
1 stop23h 37mAmerican Airlines
Deal found 4/17$494
This American Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/117:43 pmDSM - SJO
2 stops18h 17mAmerican Airlines
Tue 10/2112:55 pmSJO - DSM
2 stops19h 12mAmerican Airlines
Deal found 4/16$510
This American Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/115:18 amDSM - BZE
1 stop10h 01mAmerican Airlines
Tue 11/184:15 pmBZE - DSM
1 stop7h 30mAmerican Airlines
Deal found 4/16$514
This American Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/285:00 amDSM - LIR
1 stop9h 05mAmerican Airlines
Tue 5/132:05 pmLIR - DSM
2 stops20h 08mAmerican Airlines
Deal found 4/17$517

Cheapflights Fare Finder

Customize your flight search to find flights from Des Moines to Central America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
Use the filters below to find and compare flights from Des Moines to Central America that are best for you.

Fly from

Des Moines

Fly to

Central America

Route

Depart

Return

Price

Des MoinesSan José

DSM - SJO

DSMSJO

Des Moines

Fri 5/16

8:30 am-11:33 am

1 stop28h 03m

San José Juan Santamaria Intl

Sun 5/18

12:28 pm-3:53 pm

1 stop26h 25m

$347

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Sat 5/31

2:54 pm-11:33 am

2 stops21h 39m

Guatemala City La Aurora

Thu 6/5

12:59 am-1:55 pm

1 stop11h 56m

$387

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Sat 5/31

5:30 pm-12:48 pm

2 stops19h 18m

Panama City Tocumen Intl

Sat 6/7

2:13 pm-9:38 am

2 stops19h 25m

$428

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Sat 5/31

5:35 am-12:48 pm

1 stop7h 13m

Panama City Tocumen Intl

Sat 6/7

2:13 pm-10:30 pm

1 stop8h 17m

$441

Des MoinesSan Salvador

DSM - SAL

DSMSAL

Des Moines

Sat 5/17

6:45 pm-2:23 pm

2 stops20h 38m

San Salvador El Salvador Intl

Sat 5/24

1:25 pm-10:27 am

2 stops20h 02m

$458

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Sat 5/24

6:45 pm-4:12 pm

2 stops21h 27m

Panama City Tocumen Intl

Sat 5/31

3:20 pm-9:22 pm

2 stops30h 02m

$461

Des MoinesSan Salvador

DSM - SAL

DSMSAL

Des Moines

Thu 7/24

5:00 am-7:56 pm

2 stops15h 56m

San Salvador El Salvador Intl

Thu 8/21

1:10 pm-9:03 am

2 stops18h 53m

$469

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Sat 5/31

4:04 pm-12:19 pm

2 stops20h 15m

Panama City Tocumen Intl

Sat 6/7

3:20 pm-9:07 am

2 stops17h 47m

$489

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Mon 9/1

5:26 am-4:59 pm

1 stop12h 33m

Guatemala City La Aurora

Mon 9/8

8:25 am-9:02 am

1 stop23h 37m

$494

Des MoinesSan José

DSM - SJO

DSMSJO

Des Moines

Sat 10/11

7:43 pm-1:00 pm

2 stops18h 17m

San José Juan Santamaria Intl

Tue 10/21

12:55 pm-9:07 am

2 stops19h 12m

$510

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/15

Showing 1-10 of 40 results
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Best time to book a flight from Des Moines to Central America

Have a flexible travel schedule? Discover the best time to fly to Central America from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Central America

What is the cheapest month to book a flight from Des Moines to Central America?

Currently, September is the cheapest month in which you can book a flight from Des Moines to Central America (average of $398). Flying from Des Moines to Central America in March is currently the most expensive (average of $555). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to CA?

Find hourly flight availability from Des Moines to Central America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 17, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Des Moines to Central America as you normally would.

Rainfall in Central America by month

Plan your trip to Central America by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Central America ranges from 0.0 - 13.0 inches per month. August is typically the wettest month, when rainfall can reach 13.0 in. February is typically the driest time to visit Central America when rainfall is around 0.0 in.

Temperature in Central America by month

Plan your trip to Central America by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Central America, use this chart to help with planning. For those seeking warmer temperatures, March is the ideal time of year to visit, when temperatures reach an average of 77.0 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 73.4 F).

Reviews of airlines servicing Central America

Get insights into the airlines that provide service to Central America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Central America. Reviews last updated April 17, 2025.
Delta
8.0
Very good
7,916 reviews

Boarding

8.2

Comfort

7.9

Overall

8.0

Food

7.3

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,916 reviews
Delta
8.0
Very good
7,916 reviews

Boarding

8.2

Comfort

7.9

Overall

8.0

Food

7.3

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
KLM
7.8
Good
1,327 reviews
Delta
8.0
Very good
7,916 reviews

Boarding

8.2

Comfort

7.9

Overall

8.0

Food

7.3

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Copa Airlines
7.6
Good
1,409 reviews
Delta
8.0
Very good
7,916 reviews

Boarding

8.2

Comfort

7.9

Overall

8.0

Food

7.3

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
United Airlines
7.4
Good
8,667 reviews
Delta
8.0
Very good
7,916 reviews

Boarding

8.2

Comfort

7.9

Overall

8.0

Food

7.3

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,916 reviews

Boarding

8.2

Comfort

7.9

Overall

8.0

Food

7.3

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Central America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Central America?

    Most people fly from Des Moines (DSM) if they book a flight from Des Moines to Central America. Des Moines is conveniently located just 3.6 mi from Des Moines’s city center.

  • What are the cheapest airlines to fly from Des Moines to Central America one-way?

    To fly one-way, consider booking your trip with Delta, which is currently one of the cheapest options available, starting at $188. American Airlines flights start at $258 while deals on United Airlines start at $279 one-way.

  • What are the most popular routes from Des Moines to Central America?

    The most popular flight routes from Des Moines to Central America are Des Moines - San José Juan Santamaria Intl, Des Moines - Belize City Philip S.W.Goldson and Des Moines - San Salvador El Salvador Intl.

  • Can I find deals for flights from Des Moines to Central America that include hotel bookings?

    Yes. In addition to deals on Des Moines to Central America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Central America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Central America.

  • Can I find deals for business class flights from Des Moines to Central America?

    Yes. Cheapflights offers flight deals from Des Moines to Central America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Central America?

    Currently, September is the cheapest month in which you can book a flight from Des Moines to Central America (average of $398). Flying from Des Moines to Central America in March is currently the most expensive (average of $555). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Alternative routes for Des Moines to Central America

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Des Moines to Central America

Discover the top 4 airlines that operate flights from Des Moines to Central America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$289Average$659FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$349Average$679FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$354Average$666FlexibilityNo cancel feeOn-time71%
AviancaCheapest$456Average$564FlexibilityNo cancel feeOn-time71%

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