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Cayman Islands

$228+ Cheap flights from St. Louis (STL) to the Cayman Islands

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/1. Fares are subject to change and may not be available on all flights or dates of travel.
STL — GCM
Feb 25 — Mar 41
Tue 2/25
Tue 3/4
1 adult, Economy
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Cheap flight deals from St. Louis to Cayman Islands

Keep the following information in mind while searching for St. Louis to Cayman Islands flight deals. Data was last updated February 20, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$484
(Delta)

One-way from

$228
(United Airlines)

Popular in

March

Cheapest in

April

Average price

$607
Provider with most accurate pricing for Lambert-St Louis-George Town Owen Roberts Intl flight deals.
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Provider most trusted by Cheapflights users for Lambert-St Louis-George Town Owen Roberts Intl flights.
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From Lambert-St Louis to Cayman Islands
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One-way flight from Lambert-St Louis to Cayman Islands
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Highest demand for flights based on searches. 7% potential increase in price ($49 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($21 potential savings vs. average RT price).
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Average for round-trip flights in February 2025
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Find flight deals from St. Louis to Cayman Islands

Cheapest flights from St. Louis to Cayman Islands
Explore the most affordable flight options available from St. Louis to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 20, 2025.

This Delta deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/186:00 amSTL - GCM
1 stop5h 38mDelta
Tue 3/251:03 pmGCM - STL
1 stop10h 28mDelta
Deal found 2/18$484
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/206:24 pmSTL - GCM
2 stops17h 21mAmerican Airlines
Mon 3/243:34 pmGCM - STL
2 stops18h 08mAmerican Airlines
Deal found 2/19$488
This United Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/296:15 amSTL - GCM
1 stop9h 35mUnited Airlines
Tue 4/11:35 pmGCM - STL
1 stop8h 34mUnited Airlines
Deal found 2/19$511
This Southwest deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/299:10 pmSTL - GCM
2 stops14h 40mSouthwest
Tue 4/112:45 pmGCM - STL
2 stops7h 45mSouthwest
Deal found 2/19$515
This Mytrip deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/1612:15 pmSTL - GCM
3 stops33h 05mMultiple Airlines
Fri 3/214:45 pmGCM - STL
3 stops43h 00mMultiple Airlines
Deal found 2/19$763

Find flights from St. Louis to Cayman Islands within your budget

Customize your flight search to find flights from St. Louis to Cayman Islands that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.

Fly from

St. Louis

Fly to

Cayman Islands

Route

Depart

Return

Price

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Tue 3/18

6:00 am-11:38 am

1 stop5h 38m

George Town Owen Roberts Intl

Tue 3/25

1:03 pm-11:31 pm

1 stop10h 28m

$484

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Thu 3/20

7:13 am-1:25 pm

1 stop6h 12m

George Town Owen Roberts Intl

Mon 3/24

3:34 pm-8:09 am

2 stops16h 35m

$488

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Sat 3/29

6:15 am-3:50 pm

1 stop9h 35m

George Town Owen Roberts Intl

Tue 4/1

1:35 pm-10:09 pm

1 stop8h 34m

$511

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Sat 3/29

9:10 pm-11:50 am

2 stops14h 40m

George Town Owen Roberts Intl

Tue 4/1

12:45 pm-8:30 pm

2 stops7h 45m

$515

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Sun 3/16

12:15 pm-9:20 pm

3 stops33h 05m

George Town Owen Roberts Intl

Fri 3/21

4:45 pm-11:45 am

3 stops43h 00m

$763

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Sat 3/1

8:40 am-4:50 pm

1 stop7h 10m

$228

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Sat 3/1

9:50 am-7:03 pm

3 stops32h 13m

$285

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/19

Best time to book a flight from St. Louis to Cayman Islands

Have a flexible travel schedule? Discover the best time to fly to Cayman Islands from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from St. Louis to Cayman Islands

Get recent, data-driven insights about flights from St. Louis to Cayman Islands including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from St. Louis to Cayman Islands?

Currently, January is the cheapest month in which you can book a flight from St. Louis to Cayman Islands (average of $467). Flying from St. Louis to Cayman Islands in March is currently the most expensive (average of $594). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Cayman Islands

Get insights into the airlines that provide service to Cayman Islands. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cayman Islands. Reviews last updated February 20, 2025.
Southwest
8.1
Very good
4,411 reviews

Entertainment

7.6

Boarding

8.2

Overall

8.1

Comfort

8.1

Food

7.1

Crew

8.7

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Southwest
8.1
Very good
4,411 reviews
Southwest
8.1
Very good
4,411 reviews

Entertainment

7.6

Boarding

8.2

Overall

8.1

Comfort

8.1

Food

7.1

Crew

8.7

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Delta
8.0
Very good
8,219 reviews
Southwest
8.1
Very good
4,411 reviews

Entertainment

7.6

Boarding

8.2

Overall

8.1

Comfort

8.1

Food

7.1

Crew

8.7

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

United Airlines
7.4
Good
8,765 reviews
Southwest
8.1
Very good
4,411 reviews

Entertainment

7.6

Boarding

8.2

Overall

8.1

Comfort

8.1

Food

7.1

Crew

8.7

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

American Airlines
7.2
Good
10,000 reviews
Southwest
8.1
Very good
4,411 reviews

Entertainment

7.6

Boarding

8.2

Overall

8.1

Comfort

8.1

Food

7.1

Crew

8.7

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Cayman Islands. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from St. Louis to Cayman Islands?

    Located just 12.7 mi from the city center, Lambert-St Louis (STL) is the airport most travelers will use when flying to Cayman Islands from St. Louis.

  • Can I find deals for flights from St. Louis to Cayman Islands that include hotel bookings?

    Yes. In addition to deals on St. Louis to Cayman Islands flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Cayman Islands?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Cayman Islands.

  • Can I find deals for business class flights from St. Louis to Cayman Islands?

    Yes. Cheapflights offers flight deals from St. Louis to Cayman Islands by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from St. Louis to Cayman Islands?

    Currently, January is the cheapest month in which you can book a flight from St. Louis to Cayman Islands (average of $467). Flying from St. Louis to Cayman Islands in March is currently the most expensive (average of $594). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for St. Louis to Cayman Islands

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from St. Louis to Cayman Islands

Discover the top 3 airlines that operate flights from St. Louis to Cayman Islands. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$439Average$555FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$456Average$659FlexibilityNo cancel feeOn-time69%
DeltaCheapest$471Average$597FlexibilityNo cancel feeOn-timeN/A
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