Cayman Islands

$159+ Cheap flights from South Carolina to the Cayman Islands

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/20. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — GCM
Feb 25 — Mar 41
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Cheap flight deals from South Carolina to Cayman Islands

Keep the following information in mind while searching for South Carolina to Cayman Islands flight deals. Data was last updated February 20, 2025.

Round-trip from

$458
(American Airlines)

One-way from

$159
(Kiwi.com)

Popular in

December

Cheapest in

July

Average price

$609
From South Carolina to Cayman Islands
One-way flight from South Carolina to Cayman Islands
Highest demand for flights based on searches. 25% potential increase in price ($223 potential increase over avg. RT price).
Cheapest flight prices on average. 13% potential price decrease ($81 potential savings vs. average RT price).
Average for round-trip flights in February 2025

Find flight deals from South Carolina to Cayman Islands

Cheapest flights from South Carolina to Cayman Islands
Explore the most affordable flight options available from South Carolina to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 20, 2025.

This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/228:25 pmCHS - GCM
1 stop16h 20mAmerican Airlines
Thu 3/273:34 pmGCM - CHS
1 stop7h 12mAmerican Airlines
Deal found 2/19$458
This Kiwi.com deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/2010:20 pmCLT - GCM
1 stop14h 20mMultiple Airlines
Mon 3/247:00 amGCM - CLT
1 stop9h 16mMultiple Airlines
Deal found 2/20$467
This United Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/226:52 amCHS - GCM
1 stop6h 38mUnited Airlines
Sat 4/264:15 pmGCM - CHS
1 stop17h 01mUnited Airlines
Deal found 2/20$498
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/89:00 amCLT - GCM
Nonstop3h 05mAmerican Airlines
Thu 7/1712:45 pmGCM - CLT
Nonstop3h 00mAmerican Airlines
Deal found 2/19$535
This Mytrip deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/107:00 amCHS - GCM
3 stops15h 20mMultiple Airlines
Fri 3/2811:05 amGCM - CHS
2 stops28h 29mMultiple Airlines
Deal found 2/20$573
This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/207:00 amCLT - GCM
1 stop5h 31mDelta
Sat 7/261:00 pmGCM - CLT
1 stop7h 06mDelta
Deal found 2/20$575
This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/265:40 amSAV - GCM
1 stop6h 58mDelta
Mon 3/311:03 pmGCM - SAV
1 stop9h 54mDelta
Deal found 2/20$575
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/228:35 pmGSP - GCM
1 stop15h 45mAmerican Airlines
Thu 5/2912:25 pmGCM - GSP
1 stop10h 22mAmerican Airlines
Deal found 2/20$582
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/258:44 pmCAE - GCM
1 stop15h 21mAmerican Airlines
Tue 9/3012:45 pmGCM - CAE
1 stop10h 19mAmerican Airlines
Deal found 2/20$635
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/269:08 amSAV - GCM
1 stop5h 17mAmerican Airlines
Mon 3/3112:00 pmGCM - SAV
2 stops10h 50mAmerican Airlines
Deal found 2/20$689
This United deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/116:13 amCLT - GCM
1 stop7h 17mUnited Airlines
Sun 4/201:35 pmGCM - CLT
1 stop7h 24mUnited Airlines
Deal found 2/19$690
This Southwest deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/158:20 pmCLT - GCM
2 stops16h 30mSouthwest
Fri 6/2012:45 pmGCM - CLT
2 stops9h 50mSouthwest
Deal found 2/20$790

Find flights from South Carolina to Cayman Islands within your budget

Customize your flight search to find flights from South Carolina to Cayman Islands that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.

Fly from

South Carolina

Fly to

Cayman Islands

Route

Depart

Return

Price

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Sat 3/22

8:25 pm-11:45 am

1 stop16h 20m

George Town Owen Roberts Intl

Thu 3/27

3:34 pm-11:46 pm

1 stop7h 12m

$458

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Thu 3/20

10:20 pm-11:40 am

1 stop14h 20m

George Town Owen Roberts Intl

Mon 3/24

7:00 am-5:16 pm

1 stop9h 16m

$467

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Tue 4/22

6:52 am-12:30 pm

1 stop6h 38m

George Town Owen Roberts Intl

Sat 4/26

4:15 pm-10:16 am

1 stop17h 01m

$498

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Tue 7/8

9:00 am-11:05 am

Nonstop3h 05m

George Town Owen Roberts Intl

Thu 7/17

12:45 pm-4:45 pm

Nonstop3h 00m

$535

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Mon 3/10

7:00 am-9:20 pm

3 stops15h 20m

George Town Owen Roberts Intl

Fri 3/28

11:05 am-4:34 pm

2 stops28h 29m

$573

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Sun 7/20

7:00 am-11:31 am

1 stop5h 31m

George Town Owen Roberts Intl

Sat 7/26

1:00 pm-9:06 pm

1 stop7h 06m

$575

SavannahGeorge Town

SAV - GCM

SAVGCM

Savannah/Hilton Head

Wed 3/26

5:40 am-11:38 am

1 stop6h 58m

George Town Owen Roberts Intl

Mon 3/31

1:03 pm-11:57 pm

1 stop9h 54m

$575

GreenvilleGeorge Town

GSP - GCM

GSPGCM

Greenville

Thu 5/22

8:35 pm-11:20 am

1 stop15h 45m

George Town Owen Roberts Intl

Thu 5/29

12:25 pm-11:47 pm

1 stop10h 22m

$582

SavannahGeorge Town

SAV - GCM

SAVGCM

Savannah/Hilton Head

Wed 3/26

9:08 am-1:25 pm

1 stop5h 17m

George Town Owen Roberts Intl

Mon 3/31

12:00 pm-11:50 pm

2 stops10h 50m

$689

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Fri 4/11

6:13 am-12:30 pm

1 stop7h 17m

George Town Owen Roberts Intl

Sun 4/20

1:35 pm-9:59 pm

1 stop7h 24m

$690

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/18

Showing 1-10 of 23 results
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Best time to book a flight from South Carolina to Cayman Islands

Have a flexible travel schedule? Discover the best time to fly to Cayman Islands from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from South Carolina to Cayman Islands

Get recent, data-driven insights about flights from South Carolina to Cayman Islands including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from South Carolina to Cayman Islands?

Currently, January is the cheapest month in which you can book a flight from South Carolina to Cayman Islands (average of $467). Flying from South Carolina to Cayman Islands in March is currently the most expensive (average of $594). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to KY?

Find hourly flight availability from South Carolina to Cayman Islands. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 20, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from South Carolina to Cayman Islands as you normally would.

Reviews of airlines servicing Cayman Islands

Get insights into the airlines that provide service to Cayman Islands. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cayman Islands. Reviews last updated February 20, 2025.
Read reviews from past customers who have flown Southwest, Delta and United Airlines from South Carolina to Cayman Islands. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Food

7.1

Overall

8.1

Comfort

8.1

Crew

8.7

Entertainment

7.6

Boarding

8.2

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Food

7.1

Overall

8.1

Comfort

8.1

Crew

8.7

Entertainment

7.6

Boarding

8.2

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

8.0
Very good

Food

7.1

Overall

8.1

Comfort

8.1

Crew

8.7

Entertainment

7.6

Boarding

8.2

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Food

7.1

Overall

8.1

Comfort

8.1

Crew

8.7

Entertainment

7.6

Boarding

8.2

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Food

7.1

Overall

8.1

Comfort

8.1

Crew

8.7

Entertainment

7.6

Boarding

8.2

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Food

7.1

Overall

8.1

Comfort

8.1

Crew

8.7

Entertainment

7.6

Boarding

8.2

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Cayman Islands. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What are the cheapest airlines to fly from South Carolina to Cayman Islands one-way?

    One-way options have recently been found by users for as low as $211 on Air Canada. Other airlines that offer cheap prices include Southwest from $251 and American Airlines from $308 one-way.

  • Can I find deals for flights from South Carolina to Cayman Islands that include hotel bookings?

    Yes. In addition to deals on South Carolina to Cayman Islands flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Cayman Islands?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Cayman Islands.

  • Can I find deals for business class flights from South Carolina to Cayman Islands?

    Yes. Cheapflights offers flight deals from South Carolina to Cayman Islands by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Cayman Islands?

    Currently, January is the cheapest month in which you can book a flight from South Carolina to Cayman Islands (average of $467). Flying from South Carolina to Cayman Islands in March is currently the most expensive (average of $594). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for South Carolina to Cayman Islands

See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from South Carolina to Cayman Islands

Discover the top 2 airlines that operate flights from South Carolina to Cayman Islands. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$375Average$544FlexibilityNo cancel feeOn-time71%
DeltaCheapest$469Average$674FlexibilityNo cancel feeOn-timeN/A
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