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Cayman Islands

$187+ Cheap flights from South Carolina to the Cayman Islands

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/23. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — GCM
Apr 29 — May 61
Tue 4/29
Tue 5/6
1 adult, Economy
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Cheap flight deals from South Carolina to Cayman Islands

Keep the following information in mind while searching for South Carolina to Cayman Islands flight deals. Data was last updated April 24, 2025.

Round-trip from

$462
(American Airlines)

One-way from

$187
(Kiwi.com)
From South Carolina to Cayman Islands
Search Deals
One-way flight from South Carolina to Cayman Islands
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Find flight deals from South Carolina to Cayman Islands

Cheapest flights from South Carolina to Cayman Islands
Explore the most affordable flight options available from South Carolina to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 24, 2025.

This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/198:43 pmCHS - GCM
1 stop15h 37mAmerican Airlines
Thu 5/2212:25 pmGCM - CHS
1 stop8h 39mAmerican Airlines
Deal found 4/23$462
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/133:19 pmCLT - GCM
1 stop7h 01mMultiple Airlines
Wed 6/1811:30 amGCM - CLT
1 stop19h 39mMultiple Airlines
Deal found 4/23$489
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/75:50 amCHS - GCM
1 stop10h 20mUnited Airlines
Sat 6/144:15 pmGCM - CHS
1 stop16h 59mUnited Airlines
Deal found 4/23$506
This Delta deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/297:00 amSAV - GCM
1 stop5h 31mDelta
Sat 8/21:00 pmGCM - SAV
1 stop9h 46mDelta
Deal found 4/24$513
This American Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/226:26 amGSP - GCM
1 stop5h 54mAmerican Airlines
Thu 5/2912:10 pmGCM - GSP
1 stop10h 08mAmerican Airlines
Deal found 4/24$545
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/179:00 amCLT - GCM
Nonstop3h 05mAmerican Airlines
Fri 10/2412:45 pmGCM - CLT
Nonstop3h 00mAmerican Airlines
Deal found 4/23$550
This Air Canada deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/188:30 amCLT - GCM
1 stop28h 25mAir Canada
Thu 6/2612:50 pmGCM - CLT
1 stop7h 31mAir Canada
Deal found 4/22$559
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/299:36 pmCHS - GCM
1 stop20h 44mMultiple Airlines
Sun 7/612:40 pmGCM - CHS
1 stop20h 50mMultiple Airlines
Deal found 4/23$570
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/87:00 amCLT - GCM
1 stop5h 31mDelta
Thu 7/1712:50 pmGCM - CLT
1 stop5h 34mDelta
Deal found 4/22$590
This Southwest deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/137:45 pmCLT - GCM
2 stops15h 50mSouthwest
Wed 6/1812:45 pmGCM - CLT
2 stops8h 55mSouthwest
Deal found 4/23$595
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/185:40 amCAE - GCM
1 stop6h 51mDelta
Mon 9/2212:53 pmGCM - CAE
1 stop7h 55mDelta
Deal found 4/23$633
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/308:41 pmCAE - GCM
1 stop15h 19mAmerican Airlines
Sat 9/612:45 pmGCM - CAE
1 stop5h 19mAmerican Airlines
Deal found 4/23$635

Cheapflights Fare Finder

Customize your flight search to find flights from South Carolina to Cayman Islands that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2025.
Use the filters below to find and compare flights from South Carolina to the Cayman Islands that are best for you.

Fly from

South Carolina

Fly to

Cayman Islands

Route

Depart

Return

Price

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Mon 5/19

8:43 pm-11:20 am

1 stop15h 37m

George Town Owen Roberts Intl

Thu 5/22

12:25 pm-10:04 pm

1 stop8h 39m

$462

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Fri 6/13

3:19 pm-9:20 pm

1 stop7h 01m

George Town Owen Roberts Intl

Wed 6/18

11:30 am-8:09 am

1 stop19h 39m

$489

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Sat 6/7

5:50 am-3:10 pm

1 stop10h 20m

George Town Owen Roberts Intl

Sat 6/14

4:15 pm-10:14 am

1 stop16h 59m

$506

SavannahGeorge Town

SAV - GCM

SAVGCM

Savannah/Hilton Head

Tue 7/29

7:00 am-11:31 am

1 stop5h 31m

George Town Owen Roberts Intl

Sat 8/2

1:00 pm-11:46 pm

1 stop9h 46m

$513

GreenvilleGeorge Town

GSP - GCM

GSPGCM

Greenville

Thu 5/22

6:26 am-11:20 am

1 stop5h 54m

George Town Owen Roberts Intl

Thu 5/29

12:10 pm-11:18 pm

1 stop10h 08m

$545

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Fri 10/17

9:00 am-11:05 am

Nonstop3h 05m

George Town Owen Roberts Intl

Fri 10/24

12:45 pm-4:45 pm

Nonstop3h 00m

$550

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Wed 6/18

8:30 am-11:55 am

1 stop28h 25m

George Town Owen Roberts Intl

Thu 6/26

12:50 pm-9:21 pm

1 stop7h 31m

$559

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Sun 6/29

9:36 pm-5:20 pm

1 stop20h 44m

George Town Owen Roberts Intl

Sun 7/6

12:40 pm-10:30 am

1 stop20h 50m

$570

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Tue 7/8

5:30 am-11:31 am

1 stop7h 01m

George Town Owen Roberts Intl

Fri 7/18

12:50 pm-10:25 pm

1 stop8h 35m

$590

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Fri 6/13

7:45 pm-10:35 am

2 stops15h 50m

George Town Owen Roberts Intl

Wed 6/18

12:45 pm-10:40 pm

2 stops8h 55m

$595

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/22

Showing 1-10 of 22 results
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Best time to book a flight from South Carolina to Cayman Islands

Have a flexible travel schedule? Discover the best time to fly to Cayman Islands from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to the Cayman Islands

What is the cheapest month to book a flight from South Carolina to Cayman Islands?

Currently, January is the cheapest month in which you can book a flight from South Carolina to Cayman Islands (average of $467). Flying from South Carolina to Cayman Islands in March is currently the most expensive (average of $594). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Cayman Islands

Get insights into the airlines that provide service to Cayman Islands. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cayman Islands. Reviews last updated April 24, 2025.
Read reviews from past customers who have flown Southwest, Delta and United Airlines from South Carolina to Cayman Islands. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,286 reviews

Overall

8.0

Food

7.1

Comfort

8.0

Entertainment

7.6

Crew

8.6

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
Southwest
8.0
Very good
4,286 reviews
Southwest
8.0
Very good
4,286 reviews

Overall

8.0

Food

7.1

Comfort

8.0

Entertainment

7.6

Crew

8.6

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
Delta
8.0
Very good
7,920 reviews
Southwest
8.0
Very good
4,286 reviews

Overall

8.0

Food

7.1

Comfort

8.0

Entertainment

7.6

Crew

8.6

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
United Airlines
7.4
Good
8,685 reviews
Southwest
8.0
Very good
4,286 reviews

Overall

8.0

Food

7.1

Comfort

8.0

Entertainment

7.6

Crew

8.6

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,286 reviews

Overall

8.0

Food

7.1

Comfort

8.0

Entertainment

7.6

Crew

8.6

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
WestJet
7.2
Good
2,816 reviews
Southwest
8.0
Very good
4,286 reviews

Overall

8.0

Food

7.1

Comfort

8.0

Entertainment

7.6

Crew

8.6

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Cayman Islands. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from South Carolina to Cayman Islands one-way?

    One-way options have recently been found by users for as low as $218 on Air Canada. Other airlines that offer cheap prices include American Airlines from $303 and Delta from $308 one-way.

  • Can I find deals for flights from South Carolina to Cayman Islands that include hotel bookings?

    Yes. In addition to deals on South Carolina to Cayman Islands flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Cayman Islands?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Cayman Islands.

  • Can I find deals for business class flights from South Carolina to Cayman Islands?

    Yes. Cheapflights offers flight deals from South Carolina to Cayman Islands by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Cayman Islands?

    Currently, January is the cheapest month in which you can book a flight from South Carolina to Cayman Islands (average of $467). Flying from South Carolina to Cayman Islands in March is currently the most expensive (average of $594). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from South Carolina to Cayman Islands

Discover the top 2 airlines that operate flights from South Carolina to Cayman Islands. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$375Average$579FlexibilityNo cancel feeOn-time71%
DeltaCheapest$460Average$627FlexibilityNo cancel feeOn-timeN/A

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