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Cayman Islands

$170+ Cheap flights from South Carolina to the Cayman Islands

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/1. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — GCM
Apr 8 — Apr 151
Tue 4/8
Tue 4/15
1 adult, Economy
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Cheap flight deals from South Carolina to Cayman Islands

Keep the following information in mind while searching for South Carolina to Cayman Islands flight deals. Data was last updated April 3, 2025.

Round-trip from

$395
(American Airlines)

One-way from

$170
(Kiwi.com)

Popular in

December

Cheapest in

May

Average price

$774
From South Carolina to Cayman Islands
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One-way flight from South Carolina to Cayman Islands
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Highest demand for flights based on searches. 25% potential increase in price ($212 potential increase over avg. RT price).
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Cheapest flight prices on average. 13% potential price decrease ($76 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from South Carolina to Cayman Islands

Cheapest flights from South Carolina to Cayman Islands
Explore the most affordable flight options available from South Carolina to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 3, 2025.

This American Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/198:48 pmCHS - GCM
2 stops16h 47mAmerican Airlines
Sun 9/2112:45 pmGCM - CHS
1 stop10h 28mAmerican Airlines
Deal found 4/2$395
This Mytrip deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/37:11 pmCLT - GCM
1 stop17h 29mMultiple Airlines
Thu 5/811:30 amGCM - CLT
1 stop22h 33mMultiple Airlines
Deal found 4/1$457
This Delta deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/156:30 amCHS - GCM
1 stop6h 01mDelta
Mon 9/1512:53 pmGCM - CHS
1 stop8h 11mDelta
Deal found 4/1$496
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/285:36 amGSP - GCM
1 stop6h 24mAmerican Airlines
Mon 9/112:45 pmGCM - GSP
1 stop7h 36mAmerican Airlines
Deal found 4/1$506
This Delta deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/66:52 amCLT - GCM
1 stop5h 33mDelta
Tue 7/1512:50 pmGCM - CLT
1 stop5h 34mDelta
Deal found 4/2$540
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/309:25 amCLT - GCM
Nonstop2h 50mAmerican Airlines
Mon 7/712:25 pmGCM - CLT
Nonstop3h 10mAmerican Airlines
Deal found 4/1$550
This United Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/66:00 amCHS - GCM
1 stop8h 35mUnited Airlines
Wed 4/912:55 pmGCM - CHS
1 stop9h 52mUnited Airlines
Deal found 4/2$553
This Air Canada deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/118:30 amCLT - GCM
1 stop28h 25mAir Canada
Thu 5/1512:50 pmGCM - CLT
1 stop7h 31mAir Canada
Deal found 4/2$553
This Delta deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/295:30 amSAV - GCM
1 stop7h 01mDelta
Sat 8/21:00 pmGCM - SAV
1 stop9h 46mDelta
Deal found 4/2$575
This Mytrip deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/110:25 amCHS - GCM
3 stops26h 15mMultiple Airlines
Thu 5/811:30 amGCM - CHS
2 stops33h 39mMultiple Airlines
Deal found 4/2$596
This United Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/107:00 amCLT - GCM
1 stop6h 30mUnited Airlines
Thu 7/171:35 pmGCM - CLT
1 stop7h 22mUnited Airlines
Deal found 4/2$630
This American Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/308:41 pmCAE - GCM
1 stop15h 19mAmerican Airlines
Sat 9/612:45 pmGCM - CAE
1 stop7h 43mAmerican Airlines
Deal found 4/2$635

Cheapflights Fare Finder

Customize your flight search to find flights from South Carolina to Cayman Islands that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 3, 2025.
Use the filters below to find and compare flights from South Carolina to the Cayman Islands that are best for you.

Fly from

South Carolina

Fly to

Cayman Islands

Route

Depart

Return

Price

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Fri 9/19

8:48 pm-12:35 pm

2 stops16h 47m

George Town Owen Roberts Intl

Sun 9/21

12:45 pm-12:13 am

1 stop10h 28m

$395

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Sat 5/3

7:11 pm-11:40 am

1 stop17h 29m

George Town Owen Roberts Intl

Thu 5/8

11:30 am-11:03 am

1 stop22h 33m

$457

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Fri 8/15

6:30 am-11:31 am

1 stop6h 01m

George Town Owen Roberts Intl

Mon 9/15

12:53 pm-10:04 pm

1 stop8h 11m

$496

GreenvilleGeorge Town

GSP - GCM

GSPGCM

Greenville

Thu 8/28

5:36 am-11:00 am

1 stop6h 24m

George Town Owen Roberts Intl

Mon 9/1

12:45 pm-9:21 pm

1 stop7h 36m

$506

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Sun 7/6

6:52 am-11:25 am

1 stop5h 33m

George Town Owen Roberts Intl

Wed 7/16

12:50 pm-9:06 pm

1 stop7h 16m

$540

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Mon 6/30

9:25 am-11:15 am

Nonstop2h 50m

George Town Owen Roberts Intl

Mon 7/7

12:25 pm-4:35 pm

Nonstop3h 10m

$550

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Sun 5/11

8:30 am-11:55 am

1 stop28h 25m

George Town Owen Roberts Intl

Thu 5/15

12:50 pm-9:21 pm

1 stop7h 31m

$553

SavannahGeorge Town

SAV - GCM

SAVGCM

Savannah/Hilton Head

Tue 7/29

5:30 am-11:31 am

1 stop7h 01m

George Town Owen Roberts Intl

Sat 8/2

1:00 pm-11:46 pm

1 stop9h 46m

$575

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Thu 5/1

10:25 am-11:40 am

3 stops26h 15m

George Town Owen Roberts Intl

Thu 5/8

11:30 am-10:09 pm

2 stops33h 39m

$596

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Thu 7/10

7:00 am-12:30 pm

1 stop6h 30m

George Town Owen Roberts Intl

Thu 7/17

1:35 pm-9:57 pm

1 stop7h 22m

$630

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/2

Showing 1-10 of 20 results
1
2

Best time to book a flight from South Carolina to Cayman Islands

Have a flexible travel schedule? Discover the best time to fly to Cayman Islands from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to the Cayman Islands

What is the cheapest month to book a flight from South Carolina to Cayman Islands?

Currently, January is the cheapest month in which you can book a flight from South Carolina to Cayman Islands (average of $467). Flying from South Carolina to Cayman Islands in March is currently the most expensive (average of $594). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Cayman Islands

Get insights into the airlines that provide service to Cayman Islands. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cayman Islands. Reviews last updated April 3, 2025.
Read reviews from past customers who have flown Delta, United Airlines and American Airlines from South Carolina to Cayman Islands. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,897 reviews

Food

7.3

Comfort

7.9

Crew

8.5

Overall

8.0

Entertainment

7.9

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,897 reviews
Delta
8.0
Very good
7,897 reviews

Food

7.3

Comfort

7.9

Crew

8.5

Overall

8.0

Entertainment

7.9

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
United Airlines
7.4
Good
8,619 reviews
Delta
8.0
Very good
7,897 reviews

Food

7.3

Comfort

7.9

Crew

8.5

Overall

8.0

Entertainment

7.9

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,897 reviews

Food

7.3

Comfort

7.9

Crew

8.5

Overall

8.0

Entertainment

7.9

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
WestJet
7.2
Good
2,795 reviews
Delta
8.0
Very good
7,897 reviews

Food

7.3

Comfort

7.9

Crew

8.5

Overall

8.0

Entertainment

7.9

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Air Canada
7.0
Good
9,028 reviews
Delta
8.0
Very good
7,897 reviews

Food

7.3

Comfort

7.9

Crew

8.5

Overall

8.0

Entertainment

7.9

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Cayman Islands. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from South Carolina to Cayman Islands one-way?

    One-way options have recently been found by users for as low as $215 on Air Canada. Other airlines that offer cheap prices include American Airlines from $303 and Delta from $308 one-way.

  • Can I find deals for flights from South Carolina to Cayman Islands that include hotel bookings?

    Yes. In addition to deals on South Carolina to Cayman Islands flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Cayman Islands?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Cayman Islands.

  • Can I find deals for business class flights from South Carolina to Cayman Islands?

    Yes. Cheapflights offers flight deals from South Carolina to Cayman Islands by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Cayman Islands?

    Currently, January is the cheapest month in which you can book a flight from South Carolina to Cayman Islands (average of $467). Flying from South Carolina to Cayman Islands in March is currently the most expensive (average of $594). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for South Carolina to Cayman Islands

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from South Carolina to Cayman Islands

Discover the top 2 airlines that operate flights from South Carolina to Cayman Islands. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 3, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$375Average$578FlexibilityNo cancel feeOn-time71%
DeltaCheapest$460Average$602FlexibilityNo cancel feeOn-timeN/A

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