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Cayman Islands

$228+ Cheap flights from Missouri to the Cayman Islands

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/1. Fares are subject to change and may not be available on all flights or dates of travel.
STL — GCM
Feb 25 — Mar 41
Tue 2/25
Tue 3/4
1 adult, Economy
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Cheap flight deals from Missouri to Cayman Islands

Keep the following information in mind while searching for Missouri to Cayman Islands flight deals. Data was last updated February 20, 2025.

Round-trip from

$484
(Delta)

One-way from

$228
(United Airlines)
From Missouri to Cayman Islands
Search Deals
One-way flight from Missouri to Cayman Islands
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Find flight deals from Missouri to Cayman Islands

Cheapest flights from Missouri to Cayman Islands
Explore the most affordable flight options available from Missouri to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 20, 2025.

This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/135:35 amMCI - GCM
1 stop6h 03mDelta
Tue 3/181:03 pmGCM - MCI
1 stop7h 04mDelta
Deal found 2/20$484
This Delta deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/186:00 amSTL - GCM
1 stop5h 38mDelta
Tue 3/251:03 pmGCM - STL
1 stop10h 28mDelta
Deal found 2/18$484
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/206:24 pmSTL - GCM
2 stops17h 21mAmerican Airlines
Mon 3/243:34 pmGCM - STL
2 stops18h 08mAmerican Airlines
Deal found 2/19$488
This United Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/296:15 amSTL - GCM
1 stop9h 35mUnited Airlines
Tue 4/11:35 pmGCM - STL
1 stop8h 34mUnited Airlines
Deal found 2/19$511
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/256:30 amMCI - GCM
1 stop6h 55mAmerican Airlines
Wed 4/212:45 pmGCM - MCI
2 stops9h 45mAmerican Airlines
Deal found 2/20$515
This Southwest deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/299:10 pmSTL - GCM
2 stops14h 40mSouthwest
Tue 4/112:45 pmGCM - STL
2 stops7h 45mSouthwest
Deal found 2/19$515
This United Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/196:05 amMCI - GCM
1 stop9h 20mUnited Airlines
Thu 3/204:40 pmGCM - MCI
1 stop16h 55mUnited Airlines
Deal found 2/20$526
This Southwest deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/239:20 pmMCI - GCM
2 stops14h 35mSouthwest
Tue 2/251:50 pmGCM - MCI
1 stop9h 20mSouthwest
Deal found 2/19$730
This Mytrip deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/1612:15 pmSTL - GCM
3 stops33h 05mMultiple Airlines
Fri 3/214:45 pmGCM - STL
3 stops43h 00mMultiple Airlines
Deal found 2/19$763
This Kiwi.com deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/138:05 pmMCI - GCM
1 stop19h 40mMultiple Airlines
Mon 3/172:00 pmGCM - MCI
2 stops20h 35mMultiple Airlines
Deal found 2/20$769
This Justfly.com deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/196:25 pmMCI - GCM
2 stops19h 35mAir Canada
Fri 3/213:00 pmGCM - MCI
2 stops23h 26mAir Canada
Deal found 2/20$2,050

Find flights from Missouri to Cayman Islands within your budget

Customize your flight search to find flights from Missouri to Cayman Islands that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.

Fly from

Missouri

Fly to

Cayman Islands

Route

Depart

Return

Price

Kansas CityGeorge Town

MCI - GCM

MCIGCM

Kansas City

Thu 3/13

5:35 am-11:38 am

1 stop6h 03m

George Town Owen Roberts Intl

Tue 3/18

1:03 pm-12:04 am

1 stop11h 01m

$484

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Tue 3/18

6:00 am-11:38 am

1 stop5h 38m

George Town Owen Roberts Intl

Tue 3/25

1:03 pm-11:31 pm

1 stop10h 28m

$484

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Thu 3/20

7:13 am-1:25 pm

1 stop6h 12m

George Town Owen Roberts Intl

Mon 3/24

3:34 pm-8:09 am

2 stops16h 35m

$488

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Sat 3/29

6:15 am-3:50 pm

1 stop9h 35m

George Town Owen Roberts Intl

Tue 4/1

1:35 pm-10:09 pm

1 stop8h 34m

$511

Kansas CityGeorge Town

MCI - GCM

MCIGCM

Kansas City

Fri 3/28

5:09 am-2:34 pm

1 stop9h 25m

George Town Owen Roberts Intl

Tue 4/1

3:34 pm-10:53 pm

1 stop7h 19m

$511

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Sat 3/29

9:10 pm-11:50 am

2 stops14h 40m

George Town Owen Roberts Intl

Tue 4/1

12:45 pm-8:30 pm

2 stops7h 45m

$515

Kansas CityGeorge Town

MCI - GCM

MCIGCM

Kansas City

Wed 4/23

6:20 am-12:30 pm

1 stop6h 10m

George Town Owen Roberts Intl

Mon 4/28

1:35 pm-10:19 pm

1 stop8h 44m

$524

Kansas CityGeorge Town

MCI - GCM

MCIGCM

Kansas City

Wed 4/23

2:04 pm-9:20 pm

3 stops31h 16m

George Town Owen Roberts Intl

Mon 4/28

2:00 pm-12:59 pm

3 stops46h 59m

$639

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Sun 3/16

12:15 pm-9:20 pm

3 stops33h 05m

George Town Owen Roberts Intl

Fri 3/21

4:45 pm-11:45 am

3 stops43h 00m

$763

Kansas CityGeorge Town

MCI - GCM

MCIGCM

Kansas City

Wed 3/19

6:25 pm-2:00 pm

2 stops19h 35m

George Town Owen Roberts Intl

Fri 3/21

3:00 pm-2:26 pm

2 stops23h 26m

$2,050

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/19

Showing 1-10 of 12 results
1
2

Best time to book a flight from Missouri to Cayman Islands

Have a flexible travel schedule? Discover the best time to fly to Cayman Islands from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Missouri to Cayman Islands

Get recent, data-driven insights about flights from Missouri to Cayman Islands including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Missouri to Cayman Islands?

Currently, January is the cheapest month in which you can book a flight from Missouri to Cayman Islands (average of $467). Flying from Missouri to Cayman Islands in March is currently the most expensive (average of $594). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to KY?

Find hourly flight availability from Missouri to Cayman Islands. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 20, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Missouri to Cayman Islands as you normally would.

Reviews of airlines servicing Cayman Islands

Get insights into the airlines that provide service to Cayman Islands. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cayman Islands. Reviews last updated February 20, 2025.
To help decide which airline to fly from Missouri to Cayman Islands, see what other customers have to say about Southwest, Delta and United Airlines. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
4,411 reviews

Comfort

8.1

Overall

8.1

Crew

8.7

Food

7.1

Boarding

8.2

Entertainment

7.6

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Southwest
8.1
Very good
4,411 reviews
Southwest
8.1
Very good
4,411 reviews

Comfort

8.1

Overall

8.1

Crew

8.7

Food

7.1

Boarding

8.2

Entertainment

7.6

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Delta
8.0
Very good
8,220 reviews
Southwest
8.1
Very good
4,411 reviews

Comfort

8.1

Overall

8.1

Crew

8.7

Food

7.1

Boarding

8.2

Entertainment

7.6

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

United Airlines
7.4
Good
8,766 reviews
Southwest
8.1
Very good
4,411 reviews

Comfort

8.1

Overall

8.1

Crew

8.7

Food

7.1

Boarding

8.2

Entertainment

7.6

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

American Airlines
7.2
Good
10,000 reviews
Southwest
8.1
Very good
4,411 reviews

Comfort

8.1

Overall

8.1

Crew

8.7

Food

7.1

Boarding

8.2

Entertainment

7.6

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Air Canada
7.0
Good
8,748 reviews
Southwest
8.1
Very good
4,411 reviews

Comfort

8.1

Overall

8.1

Crew

8.7

Food

7.1

Boarding

8.2

Entertainment

7.6

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Cayman Islands. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • Can I find deals for flights from Missouri to Cayman Islands that include hotel bookings?

    Yes. In addition to deals on Missouri to Cayman Islands flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Cayman Islands?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Cayman Islands.

  • Can I find deals for business class flights from Missouri to Cayman Islands?

    Yes. Cheapflights offers flight deals from Missouri to Cayman Islands by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Cayman Islands?

    Currently, January is the cheapest month in which you can book a flight from Missouri to Cayman Islands (average of $467). Flying from Missouri to Cayman Islands in March is currently the most expensive (average of $594). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Missouri to Cayman Islands

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Missouri to Cayman Islands

Discover the top 3 airlines that operate flights from Missouri to Cayman Islands. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$439Average$596FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$440Average$602FlexibilityNo cancel feeOn-time69%
DeltaCheapest$471Average$585FlexibilityNo cancel feeOn-timeN/A
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