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Cayman Islands

$356+ Cheap flights from Missouri to the Cayman Islands

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/10. Fares are subject to change and may not be available on all flights or dates of travel.
STL — GCM
Apr 8 — Apr 151
Tue 4/8
Tue 4/15
1 adult, Economy
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Cheap flight deals from Missouri to Cayman Islands

Keep the following information in mind while searching for Missouri to Cayman Islands flight deals. Data was last updated April 3, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$356
(American Airlines)

Popular in

December

Cheapest in

September

Average price

$582
Provider with most accurate pricing for Kansas City-George Town Owen Roberts Intl flight deals.
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Provider most trusted by Cheapflights users for Kansas City-George Town Owen Roberts Intl flights.
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From Missouri to Cayman Islands
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Highest demand for flights based on searches. 5% potential increase in price ($32 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($16 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from Missouri to Cayman Islands

Cheapest flights from Missouri to Cayman Islands
Explore the most affordable flight options available from Missouri to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 3, 2025.

This American Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/105:04 amMCI - GCM
1 stop6h 01mAmerican Airlines
Wed 9/173:15 pmGCM - MCI
1 stop8h 12mAmerican Airlines
Deal found 4/2$356
This Delta deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/106:00 amSTL - GCM
1 stop5h 25mDelta
Mon 4/1412:47 pmGCM - STL
1 stop7h 52mDelta
Deal found 4/2$484
This American Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/196:13 amSTL - GCM
2 stops8h 02mAmerican Airlines
Sat 5/310:55 amGCM - STL
2 stops8h 28mAmerican Airlines
Deal found 4/3$488
This Delta deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/146:00 amMCI - GCM
1 stop5h 31mDelta
Sat 7/191:00 pmGCM - MCI
1 stop10h 53mDelta
Deal found 4/2$578
This Mytrip deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/111:00 pmSTL - GCM
3 stops29h 04mMultiple Airlines
Mon 4/142:00 pmGCM - STL
2 stops27h 15mMultiple Airlines
Deal found 4/1$722
This United deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/106:15 amSTL - GCM
1 stop6h 15mUnited Airlines
Wed 4/161:35 pmGCM - STL
2 stops32h 13mUnited Airlines
Deal found 4/2$749
This Mytrip deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/237:58 pmMCI - GCM
3 stops18h 52mMultiple Airlines
Thu 5/2912:40 pmGCM - MCI
2 stops21h 51mMultiple Airlines
Deal found 4/1$799
This United deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/313:21 pmMCI - GCM
3 stops45h 09mUnited Airlines
Fri 6/61:35 pmGCM - MCI
2 stops21h 03mUnited Airlines
Deal found 4/2$1,079
This Southwest deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/268:40 pmSTL - GCM
2 stops15h 40mSouthwest
Sat 1/32:15 pmGCM - STL
2 stops11h 00mSouthwest
Deal found 4/2$1,930

Cheapflights Fare Finder

Customize your flight search to find flights from Missouri to Cayman Islands that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 3, 2025.
Use the filters below to find and compare flights from Missouri to the Cayman Islands that are best for you.

Fly from

Missouri

Fly to

Cayman Islands

Route

Depart

Return

Price

Kansas CityGeorge Town

MCI - GCM

MCIGCM

Kansas City

Wed 9/10

5:04 am-11:05 am

1 stop6h 01m

George Town Owen Roberts Intl

Wed 9/17

3:15 pm-11:27 pm

1 stop8h 12m

$356

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Sat 4/19

7:04 am-1:55 pm

1 stop6h 51m

George Town Owen Roberts Intl

Sat 5/3

11:55 am-7:23 pm

1 stop7h 28m

$484

Kansas CityGeorge Town

MCI - GCM

MCIGCM

Kansas City

Mon 7/14

6:00 am-11:31 am

1 stop5h 31m

George Town Owen Roberts Intl

Sat 7/19

1:00 pm-11:53 pm

1 stop10h 53m

$578

Kansas CityGeorge Town

MCI - GCM

MCIGCM

Kansas City

Fri 5/23

7:58 pm-2:50 pm

3 stops18h 52m

George Town Owen Roberts Intl

Thu 5/29

12:40 pm-10:31 am

2 stops21h 51m

$799

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Sat 6/21

5:27 pm-12:30 pm

2 stops19h 03m

George Town Owen Roberts Intl

Sat 6/28

4:45 pm-10:40 am

2 stops17h 55m

$861

Kansas CityGeorge Town

MCI - GCM

MCIGCM

Kansas City

Sat 5/31

3:21 pm-12:30 pm

3 stops45h 09m

George Town Owen Roberts Intl

Fri 6/6

1:35 pm-10:38 am

2 stops21h 03m

$1,079

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/2

Best time to book a flight from Missouri to Cayman Islands

Have a flexible travel schedule? Discover the best time to fly to Cayman Islands from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to the Cayman Islands

What is the cheapest month to book a flight from Missouri to Cayman Islands?

Currently, January is the cheapest month in which you can book a flight from Missouri to Cayman Islands (average of $467). Flying from Missouri to Cayman Islands in March is currently the most expensive (average of $594). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to KY?

Find hourly flight availability from Missouri to Cayman Islands. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 3, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Missouri to Cayman Islands as you normally would.

Reviews of airlines servicing Cayman Islands

Get insights into the airlines that provide service to Cayman Islands. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cayman Islands. Reviews last updated April 3, 2025.
To help decide which airline to fly from Missouri to Cayman Islands, see what other customers have to say about Delta, United Airlines and American Airlines. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,897 reviews

Overall

8.0

Entertainment

7.9

Crew

8.5

Comfort

7.9

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,897 reviews
Delta
8.0
Very good
7,897 reviews

Overall

8.0

Entertainment

7.9

Crew

8.5

Comfort

7.9

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
United Airlines
7.4
Good
8,619 reviews
Delta
8.0
Very good
7,897 reviews

Overall

8.0

Entertainment

7.9

Crew

8.5

Comfort

7.9

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,897 reviews

Overall

8.0

Entertainment

7.9

Crew

8.5

Comfort

7.9

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Cayman Islands. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • Can I find deals for flights from Missouri to Cayman Islands that include hotel bookings?

    Yes. In addition to deals on Missouri to Cayman Islands flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Cayman Islands?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Cayman Islands.

  • Can I find deals for business class flights from Missouri to Cayman Islands?

    Yes. Cheapflights offers flight deals from Missouri to Cayman Islands by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Cayman Islands?

    Currently, January is the cheapest month in which you can book a flight from Missouri to Cayman Islands (average of $467). Flying from Missouri to Cayman Islands in March is currently the most expensive (average of $594). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Missouri to Cayman Islands

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Missouri to Cayman Islands

Discover the top 4 airlines that operate flights from Missouri to Cayman Islands. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 3, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$426Average$580FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$439Average$627FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$440Average$587FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$486Average$636FlexibilityNo cancel feeOn-time63%

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