Cayman Islands

$212+ Cheap flights from Missouri to the Cayman Islands

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/7. Fares are subject to change and may not be available on all flights or dates of travel.
STL — GCM
Jan 26 — Feb 21
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Cheap flight deals from Missouri to Cayman Islands

Discover tips and strategies to find the most affordable flight options for your journey from Missouri (USMO) to Cayman Islands (KY0). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 21, 2025.

Round-trip from

$510
(American Airlines)

One-way from

$212
(American Airlines)
From Missouri to Cayman Islands
One-way flight from Missouri to Cayman Islands

Find flight deals from Missouri to Cayman Islands

Cheapest flights from Missouri to Cayman Islands
Explore the most affordable flight options available from Missouri to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 21, 2025.

This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/145:13 amSTL - GCM
1 stop10h 07mAmerican Airlines
Tue 2/184:00 pmGCM - STL
1 stop7h 43mAmerican Airlines
Deal found 1/20$510
This Delta deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/46:32 amMCI - GCM
1 stop6h 50mDelta
Wed 4/912:50 pmGCM - MCI
1 stop8h 51mDelta
Deal found 1/21$528
This United Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/55:36 pmSTL - GCM
2 stops21h 49mUnited Airlines
Wed 3/124:40 pmGCM - STL
1 stop17h 11mUnited Airlines
Deal found 1/20$528
This American Airlines deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/43:49 pmMCI - GCM
2 stops18h 06mAmerican Airlines
Tue 4/812:35 pmGCM - MCI
1 stop10h 28mAmerican Airlines
Deal found 1/21$532
This United Airlines deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/76:00 amMCI - GCM
1 stop7h 30mUnited Airlines
Sat 6/144:45 pmGCM - MCI
2 stops17h 44mUnited Airlines
Deal found 1/21$554
This Delta deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/316:00 amSTL - GCM
1 stop7h 35mDelta
Tue 2/112:04 pmGCM - STL
1 stop10h 32mDelta
Deal found 1/21$572
This Mytrip deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/34:04 pmMCI - GCM
3 stops23h 06mMultiple Airlines
Fri 3/147:00 amGCM - MCI
3 stops30h 46mMultiple Airlines
Deal found 1/20$701
This Mytrip deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/512:15 pmSTL - GCM
3 stops24h 25mMultiple Airlines
Wed 3/1211:30 amGCM - STL
3 stops32h 40mMultiple Airlines
Deal found 1/20$874
This Air Canada deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/129:55 amMCI - GCM
2 stops26h 45mAir Canada
Sun 2/164:00 pmGCM - MCI
2 stops30h 32mAir Canada
Deal found 1/21$1,180

Find flights from Missouri to Cayman Islands within your budget

Customize your flight search to find flights from Missouri to Cayman Islands that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2025.

Fly from

Any airport

Fly to

Any airport

Route

Depart

Return

Price

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Fri 2/14

5:13 am-4:20 pm

1 stop10h 07m

George Town Owen Roberts Intl

Tue 2/18

4:00 pm-10:43 pm

1 stop7h 43m

$510

Kansas CityGeorge Town

MCI - GCM

MCIGCM

Kansas City

Fri 4/4

6:32 am-1:22 pm

1 stop6h 50m

George Town Owen Roberts Intl

Tue 4/8

12:50 pm-7:52 pm

1 stop7h 02m

$528

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Wed 3/5

5:36 pm-4:25 pm

2 stops21h 49m

George Town Owen Roberts Intl

Wed 3/12

4:40 pm-9:51 am

1 stop17h 11m

$528

Kansas CityGeorge Town

MCI - GCM

MCIGCM

Kansas City

Fri 4/4

7:41 pm-11:20 am

2 stops15h 39m

George Town Owen Roberts Intl

Wed 4/9

12:35 pm-10:55 pm

2 stops10h 20m

$532

Kansas CityGeorge Town

MCI - GCM

MCIGCM

Kansas City

Sat 6/7

6:00 am-1:30 pm

1 stop7h 30m

George Town Owen Roberts Intl

Sat 6/14

4:45 pm-10:29 am

2 stops17h 44m

$554

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Fri 1/31

6:00 am-2:35 pm

1 stop7h 35m

George Town Owen Roberts Intl

Tue 2/11

2:04 pm-11:36 pm

1 stop10h 32m

$572

Kansas CityGeorge Town

MCI - GCM

MCIGCM

Kansas City

Mon 2/3

4:04 pm-4:10 pm

3 stops23h 06m

George Town Owen Roberts Intl

Fri 3/14

7:00 am-1:46 pm

3 stops30h 46m

$701

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Wed 3/5

12:15 pm-1:40 pm

3 stops24h 25m

George Town Owen Roberts Intl

Wed 3/12

11:30 am-8:10 pm

3 stops32h 40m

$874

Kansas CityGeorge Town

MCI - GCM

MCIGCM

Kansas City

Wed 2/12

9:55 am-1:40 pm

2 stops26h 45m

George Town Owen Roberts Intl

Sun 2/16

4:00 pm-9:32 pm

2 stops30h 32m

$1,180

Kansas CityGeorge Town

MCI - GCM

MCIGCM

Kansas City

Sat 6/7

5:59 pm-11:00 am

2 stops17h 01m

$212

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/21

Showing 1-10 of 14 results
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Best time to book a flight from Missouri to Cayman Islands

Have a flexible travel schedule? Discover the best time to fly to Cayman Islands from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Missouri to Cayman Islands

Get recent, data-driven insights about flights from Missouri to Cayman Islands including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Missouri to Cayman Islands?

Currently, January is the cheapest month in which you can book a flight from Missouri to Cayman Islands (average of $467). Flying from Missouri to Cayman Islands in March is currently the most expensive (average of $594). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to KY?

Find hourly flight availability from Missouri to Cayman Islands. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 21, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Missouri to Cayman Islands as you normally would.

Reviews of airlines servicing Cayman Islands

Get insights into the airlines that provide service to Cayman Islands. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cayman Islands. Reviews last updated January 21, 2025.
To help decide which airline to fly from Missouri to Cayman Islands, see what other customers have to say about United Airlines, American Airlines and Delta. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
8.0
Very good
8,521 reviews

Comfort

8.0

Crew

8.6

Food

7.3

Overall

8.0

Boarding

8.2

Entertainment

7.9

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

8.0
Very good
8,521 reviews
8.0
Very good
8,521 reviews

Comfort

8.0

Crew

8.6

Food

7.3

Overall

8.0

Boarding

8.2

Entertainment

7.9

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

7.4
Good
8,984 reviews
8.0
Very good
8,521 reviews

Comfort

8.0

Crew

8.6

Food

7.3

Overall

8.0

Boarding

8.2

Entertainment

7.9

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

7.2
Good
10,000 reviews
8.0
Very good
8,521 reviews

Comfort

8.0

Crew

8.6

Food

7.3

Overall

8.0

Boarding

8.2

Entertainment

7.9

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

7.0
Good
8,633 reviews
8.0
Very good
8,521 reviews

Comfort

8.0

Crew

8.6

Food

7.3

Overall

8.0

Boarding

8.2

Entertainment

7.9

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Cayman Islands. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What are the cheapest airlines to fly from Missouri to Cayman Islands one-way?

    One-way options have recently been found by users for as low as $212 on American Airlines. Other airlines that offer cheap prices include Delta from $256 and United Airlines from $9,388 one-way.

  • Can I find deals for flights from Missouri to Cayman Islands that include hotel bookings?

    Yes. In addition to deals on Missouri to Cayman Islands flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Cayman Islands?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Cayman Islands.

  • Can I find deals for business class flights from Missouri to Cayman Islands?

    Yes. Cheapflights offers flight deals from Missouri to Cayman Islands by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Cayman Islands?

    Currently, January is the cheapest month in which you can book a flight from Missouri to Cayman Islands (average of $467). Flying from Missouri to Cayman Islands in March is currently the most expensive (average of $594). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Alternative routes for Missouri to Cayman Islands

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Missouri to Cayman Islands

Discover the top 3 airlines that operate flights from Missouri to Cayman Islands. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$440Average$593FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$440Average$594FlexibilityNo cancel feeOn-time71%
DeltaCheapest$453Average$555FlexibilityNo cancel feeOn-timeN/A
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