HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Cayman Islands

$570+ Cheap flights from Knoxville (TYS) to the Cayman Islands

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/8. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — GCM
Feb 27 — Mar 61
Thu 2/27
Thu 3/6
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Knoxville to Cayman Islands with Cheapflights

1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”
2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.
3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Knoxville to Cayman Islands

Keep the following information in mind while searching for Knoxville to Cayman Islands flight deals. Data was last updated February 22, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$570
(United)

Popular in

December

Cheapest in

January

Average price

$558
Provider with most accurate pricing for Knoxville McGhee Tyson-George Town Owen Roberts Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-George Town Owen Roberts Intl flights.
Search Deals
From Knoxville McGhee Tyson to Cayman Islands
Search Deals
Highest demand for flights based on searches. 18% potential increase in price ($140 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 8% potential price decrease ($47 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2025
Search Deals

Find flight deals from Knoxville to Cayman Islands

Cheapest flights from Knoxville to Cayman Islands
Explore the most affordable flight options available from Knoxville to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 22, 2025.

This United deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/87:05 amTYS - GCM
1 stop6h 25mUnited Airlines
Mon 5/121:35 pmGCM - TYS
1 stop9h 10mUnited Airlines
Deal found 2/22$570
This American Airlines deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/37:00 amTYS - GCM
1 stop7h 10mAmerican Airlines
Sat 6/712:30 pmGCM - TYS
1 stop10h 53mAmerican Airlines
Deal found 2/21$635
This Air Canada deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/25:45 amTYS - GCM
2 stops32h 45mAir Canada
Sun 4/62:35 pmGCM - TYS
2 stops32h 24mAir Canada
Deal found 2/21$691

Find flights from Knoxville to Cayman Islands within your budget

Customize your flight search to find flights from Knoxville to Cayman Islands that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 22, 2025.

Fly from

Knoxville

Fly to

Cayman Islands

Route

Depart

Return

Price

KnoxvilleGeorge Town

TYS - GCM

TYSGCM

Knoxville McGhee Tyson

Thu 5/8

7:05 am-12:30 pm

1 stop6h 25m

George Town Owen Roberts Intl

Mon 5/12

1:35 pm-11:45 pm

1 stop9h 10m

$570

KnoxvilleGeorge Town

TYS - GCM

TYSGCM

Knoxville McGhee Tyson

Tue 6/3

7:00 am-1:10 pm

1 stop7h 10m

George Town Owen Roberts Intl

Sat 6/7

12:30 pm-12:23 am

1 stop10h 53m

$635

KnoxvilleGeorge Town

TYS - GCM

TYSGCM

Knoxville McGhee Tyson

Wed 4/2

5:45 am-1:30 pm

2 stops32h 45m

George Town Owen Roberts Intl

Sun 4/6

2:35 pm-11:59 pm

2 stops32h 24m

$691

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/22

Best time to book a flight from Knoxville to Cayman Islands

Have a flexible travel schedule? Discover the best time to fly to Cayman Islands from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Knoxville to Cayman Islands

Get recent, data-driven insights about flights from Knoxville to Cayman Islands including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Knoxville to Cayman Islands?

Currently, January is the cheapest month in which you can book a flight from Knoxville to Cayman Islands (average of $467). Flying from Knoxville to Cayman Islands in March is currently the most expensive (average of $594). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Cayman Islands

Get insights into the airlines that provide service to Cayman Islands. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cayman Islands. Reviews last updated February 22, 2025.
United Airlines
7.4
Good
8,754 reviews

Comfort

7.3

Food

6.7

Crew

8.1

Boarding

7.7

Entertainment

7.1

Overall

7.4

Reviews

1 / 20

2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!

United Airlines
7.4
Good
8,754 reviews
United Airlines
7.4
Good
8,754 reviews

Comfort

7.3

Food

6.7

Crew

8.1

Boarding

7.7

Entertainment

7.1

Overall

7.4

Reviews

1 / 20

2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!

American Airlines
7.2
Good
10,000 reviews
United Airlines
7.4
Good
8,754 reviews

Comfort

7.3

Food

6.7

Crew

8.1

Boarding

7.7

Entertainment

7.1

Overall

7.4

Reviews

1 / 20

2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!

Air Canada
7.0
Good
8,757 reviews
United Airlines
7.4
Good
8,754 reviews

Comfort

7.3

Food

6.7

Crew

8.1

Boarding

7.7

Entertainment

7.1

Overall

7.4

Reviews

1 / 20

2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Cayman Islands. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Cayman Islands?

    If you book a flight to Cayman Islands from Knoxville, you will be flying from McGhee Tyson, which is the city’s only airport. Knoxville McGhee Tyson (TYS) is located 11.3 mi from the center of Knoxville.

  • Can I find deals for flights from Knoxville to Cayman Islands that include hotel bookings?

    Yes. In addition to deals on Knoxville to Cayman Islands flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Cayman Islands?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Cayman Islands.

  • Can I find deals for business class flights from Knoxville to Cayman Islands?

    Yes. Cheapflights offers flight deals from Knoxville to Cayman Islands by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Cayman Islands?

    Currently, January is the cheapest month in which you can book a flight from Knoxville to Cayman Islands (average of $467). Flying from Knoxville to Cayman Islands in March is currently the most expensive (average of $594). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Knoxville to Cayman Islands

See prices for flight routes from nearby airports that may be better suited for you.
Nashville to Luis Munoz Marin Intl flights
Nashville to Punta Cana flights
Nashville to Montego Bay flights
Nashville to Saint Thomas Island flights
Nashville to Nassau flights
Memphis to Montego Bay flights
Memphis to Luis Munoz Marin Intl flights
Memphis to Punta Cana flights
Knoxville to Luis Munoz Marin Intl flights
Memphis to Nassau flights
Nashville to Simpson Bay flights
Nashville to Oranjestad flights
Memphis to Saint Thomas Island flights
Knoxville to Saint Thomas Island flights
Knoxville to Montego Bay flights
Nashville to Castries flights
Knoxville to Punta Cana flights
Knoxville to Providenciales flights
Memphis to Simpson Bay flights
Knoxville to Nassau flights
Knoxville to Oranjestad flights
Nashville to Santo Domingo flights
Nashville to Bridgetown flights
Nashville to Providenciales flights
Memphis to Oranjestad flights
Chattanooga to Punta Cana flights
Memphis to Castries flights
Nashville to Puerto Plata flights
Nashville to Christiansted flights
Memphis to Christiansted flights
Blountville to Luis Munoz Marin Intl flights
Chattanooga to Nassau flights
Nashville to Willemstad flights
Nashville to George Town flights
Chattanooga to Luis Munoz Marin Intl flights
Nashville to Gregory Town flights
Nashville to St. George's flights
Chattanooga to Oranjestad flights
Nashville to Basseterre flights
Nashville to Havana flights
Memphis to Puerto Plata flights
Memphis to Providenciales flights
Memphis to Santo Domingo flights
Nashville to Kingston flights
Chattanooga to Montego Bay flights
Nashville to Port of Spain flights
Nashville to St. John's flights
Memphis to Georgetown flights
Nashville to Georgetown flights
Memphis to Freeport flights

Top 2 airlines flying from Knoxville to Cayman Islands

Discover the top 2 airlines that operate flights from Knoxville to Cayman Islands. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 22, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$469Average$493FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$492Average$621FlexibilityNo cancel feeOn-time71%
100% Free
Cheapflights is completely free to use, so you can start saving the moment you arrive.
Book with Flexibility
Our users can plan ahead with confidence and find flights with no change fees
Travel Smart
Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.