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Cayman Islands

$615+ Cheap flights from Knoxville (TYS) to the Cayman Islands

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/8. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — GCM
Apr 2 — Apr 91
Wed 4/2
Wed 4/9
1 adult, Economy
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Cheap flight deals from Knoxville to Cayman Islands

Keep the following information in mind while searching for Knoxville to Cayman Islands flight deals. Data was last updated March 28, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$615
(Delta)

Popular in

December

Cheapest in

January

Average price

$510
Provider with most accurate pricing for Knoxville McGhee Tyson-George Town Owen Roberts Intl flight deals.
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Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-George Town Owen Roberts Intl flights.
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From Knoxville McGhee Tyson to Cayman Islands
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Highest demand for flights based on searches. 18% potential increase in price ($145 potential increase over avg. RT price).
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Cheapest flight prices on average. 8% potential price decrease ($47 potential savings vs. average RT price).
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Average for round-trip flights in March 2025
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Find flight deals from Knoxville to Cayman Islands

Cheapest flights from Knoxville to Cayman Islands
Explore the most affordable flight options available from Knoxville to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 28, 2025.

This Delta deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/85:45 amTYS - GCM
1 stop6h 35mDelta
Mon 5/1212:35 pmGCM - TYS
1 stop8h 23mDelta
Deal found 3/26$615
This American Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/36:51 amTYS - GCM
1 stop5h 29mAmerican Airlines
Sat 6/710:55 amGCM - TYS
1 stop7h 35mAmerican Airlines
Deal found 3/27$635
This United deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/107:05 amTYS - GCM
1 stop6h 25mUnited Airlines
Sat 5/171:35 pmGCM - TYS
1 stop9h 11mUnited Airlines
Deal found 3/26$653
This Air Canada deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/25:45 amTYS - GCM
2 stops32h 45mAir Canada
Sun 4/62:35 pmGCM - TYS
2 stops32h 24mAir Canada
Deal found 3/25$900

Cheapflights Fare Finder

Customize your flight search to find flights from Knoxville to Cayman Islands that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 28, 2025.
Use the filters below to find and compare flights from Knoxville to the Cayman Islands that are best for you.

Fly from

Knoxville

Fly to

Cayman Islands

Route

Depart

Return

Price

KnoxvilleGeorge Town

TYS - GCM

TYSGCM

Knoxville McGhee Tyson

Thu 5/8

5:45 am-11:20 am

1 stop6h 35m

George Town Owen Roberts Intl

Mon 5/12

12:35 pm-9:58 pm

1 stop8h 23m

$615

KnoxvilleGeorge Town

TYS - GCM

TYSGCM

Knoxville McGhee Tyson

Tue 6/3

6:51 am-11:20 am

1 stop5h 29m

George Town Owen Roberts Intl

Sat 6/7

10:55 am-7:30 pm

1 stop7h 35m

$635

KnoxvilleGeorge Town

TYS - GCM

TYSGCM

Knoxville McGhee Tyson

Sat 5/10

7:05 am-12:30 pm

1 stop6h 25m

George Town Owen Roberts Intl

Sat 5/17

1:35 pm-11:46 pm

1 stop9h 11m

$653

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/26

Best time to book a flight from Knoxville to Cayman Islands

Have a flexible travel schedule? Discover the best time to fly to Cayman Islands from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to the Cayman Islands

What is the cheapest month to book a flight from Knoxville to Cayman Islands?

Currently, January is the cheapest month in which you can book a flight from Knoxville to Cayman Islands (average of $467). Flying from Knoxville to Cayman Islands in March is currently the most expensive (average of $594). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Cayman Islands

Get insights into the airlines that provide service to Cayman Islands. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cayman Islands. Reviews last updated March 28, 2025.
See what other customers who have flown with Delta, United Airlines and American Airlines from Knoxville to Cayman Islands have to say. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,897 reviews

Comfort

8.0

Crew

8.5

Food

7.3

Boarding

8.2

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,897 reviews
Delta
8.0
Very good
7,897 reviews

Comfort

8.0

Crew

8.5

Food

7.3

Boarding

8.2

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
United Airlines
7.4
Good
8,603 reviews
Delta
8.0
Very good
7,897 reviews

Comfort

8.0

Crew

8.5

Food

7.3

Boarding

8.2

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,897 reviews

Comfort

8.0

Crew

8.5

Food

7.3

Boarding

8.2

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Cayman Islands. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Cayman Islands?

    If you book a flight to Cayman Islands from Knoxville, you will be flying from McGhee Tyson, which is the city’s only airport. Knoxville McGhee Tyson (TYS) is located 11.3 mi from the center of Knoxville.

  • Can I find deals for flights from Knoxville to Cayman Islands that include hotel bookings?

    Yes. In addition to deals on Knoxville to Cayman Islands flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Cayman Islands?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Cayman Islands.

  • Can I find deals for business class flights from Knoxville to Cayman Islands?

    Yes. Cheapflights offers flight deals from Knoxville to Cayman Islands by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Cayman Islands?

    Currently, January is the cheapest month in which you can book a flight from Knoxville to Cayman Islands (average of $467). Flying from Knoxville to Cayman Islands in March is currently the most expensive (average of $594). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 2 airlines flying from Knoxville to Cayman Islands

Discover the top 2 airlines that operate flights from Knoxville to Cayman Islands. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$469Average$493FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$492Average$633FlexibilityNo cancel feeOn-time71%
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