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In terms of precipitation, rainfall in Cape Girardeau ranges from 3.0 - 5.5 inches per month. May is typically the wettest month, when rainfall can reach 5.5 in. August is typically the driest time to visit Cape Girardeau when rainfall is around 3.0 in.
If weather is an important factor for your trip to Cape Girardeau, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 33.8 F).