What are the cheapest airlines flying from Des Moines to Cancún round-trip?

According to our current data, American Airlines ($439), Delta ($453), and Aeromexico ($513) offers the cheapest pricing from Des Moines to Cancún. American Airlines is priced at 24% lower than the current average price of a flight leaving 3 months from now.

What are the cheapest airlines to fly from Des Moines to Cancún one-way?

$200 is the cheapest one-way deal found within the past few days, from Frontier. You may also be able to find cheap deals on Delta and American Airlines, with prices starting from $234 and $241, respectively.

What are the most popular airlines that fly from Des Moines to Cancún?

Consider American Airlines, Aeromexico or Delta when booking your flight. These represent the most popular airlines when flying from Des Moines to Cancún.

What is the cheapest day to fly round-trip from Des Moines to Cancún?

Leaving on a Monday is a viable option for saving on travel. Heavily demanded days of the week can typically drive up the prices you see. Booking your travel for a less competitive day can save up to 22% on the overall cost on flights from Des Moines to Cancún.

How far in advance should I book a flight from Des Moines to Cancún?

To save on the cost of your flight from Des Moines to Cancún, book at least 26 days before your planned departure. Booking around this time can save you about 32% on the cost of this flight compared to booking a flight leaving this week. We have found prices from $557 if you need a flight within two weeks. For flights within the next 72 hours, you can find tickets from as low as $863.

What is the cheapest month to fly from Des Moines to Cancún?

January is one of the best times of the year to fly to Cancún from Des Moines. Prices for January average $580 per person but you can even find prices for as low as $413. The most expensive prices can be found in the month of March. Opting for a January flight can save you 18% on your journey compared to booking in March

Most accurate provider : When it comes to deals on Des Moines-Cancún flights, users find the pricing of AranGrant to be most consistent on Cheapflights vs. AranGrant Users can find the same prices on Des Moines-Cancún flight deals on Cheapflights vs. AranGrant >95% of the time. Price accuracy is based on data collected from Des Moines-Cancún flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Des Moines-Cancún flights, Cheapflights users trust AranGrant the most. AranGrant has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Cancún flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from Des Moines to Cancún that include hotel bookings?

Yes. In addition to deals on Des Moines to Cancún flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Des Moines to Cancún?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Cancún.

Can I find deals for business class flights from Des Moines to Cancún?

Yes. Cheapflights offers flight deals from Des Moines to Cancún by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$159+ Flights from Des Moines to Cancún

Home Search by date Vacation packages Hotels Flight deals Car rental Travel tips & news

Find cheap flights from Des Moines to Cancún with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Des Moines to Cancún

Most accurate provider	AranGrant 3 stars
Most trusted provider	AranGrant 3 stars
Round-trip from	$413 (Mytrip)
One-way from	$159 (Mytrip)
Popular in	March
Cheapest in	January
Average price	$542

Provider with most accurate pricing for Des Moines-Cancun flight deals.

Search Deals

Provider most trusted by Cheapflights users for Des Moines-Cancun flights.

Search Deals

From Des Moines to Cancun

Search Deals

One-way flight from Des Moines to Cancun

Search Deals

Highest demand for flights based on searches. 3% potential increase in price ($21 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 1% potential price decrease ($10 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in April 2025

Search Deals

Find flight deals from Des Moines to Cancún

Cheapest flights from Des Moines to Cancún
Explore the most affordable flight options available from Des Moines to Cancún. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 15, 2025.

Fri 5/306:30 amDSM - CUN

2 stops25h 46mMultiple Airlines

Fri 6/69:12 amCUN - DSM

2 stops32h 06mMultiple Airlines

Deal found 4/15

$413

Mon 5/125:27 pmDSM - CUN

1 stop19h 48mAmerican Airlines

Sat 5/172:40 pmCUN - DSM

1 stop9h 18mAmerican Airlines

Deal found 4/14

$439

Wed 10/111:04 amDSM - CUN

1 stop8h 58mAeromexico

Wed 10/1512:23 pmCUN - DSM

1 stop8h 27mAeromexico

Deal found 4/14

$452

Tue 6/37:01 amDSM - CUN

2 stops12h 02mDelta

Tue 6/108:35 amCUN - DSM

2 stops14h 28mDelta

Deal found 4/14

$453

Mon 4/285:10 pmDSM - CUN

2 stops16h 54mUnited Airlines

Mon 5/53:46 pmCUN - DSM

1 stop7h 53mUnited Airlines

Deal found 4/14

$514

Thu 6/265:25 amDSM - CUN

2 stops10h 00mSouthwest

Mon 6/302:45 pmCUN - DSM

2 stops9h 05mSouthwest

Deal found 4/14

$676

Thu 5/2910:59 amDSM - CUN

3 stops30h 28mWestJet

Thu 6/56:30 pmCUN - DSM

3 stops22h 36mWestJet

Deal found 4/14

$860

Fri 11/72:14 pmDSM - CUN

2 stops27h 21mLATAM Airlines

Tue 11/111:20 amCUN - DSM

2 stops22h 03mLATAM Airlines

Deal found 4/14

$2,183

Best flights from Des Moines to Cancún
Discover carefully curated flight deals from Des Moines to Cancún that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 15, 2025.

Fri 5/306:30 amDSM - CUN

2 stops25h 46mMultiple Airlines

Fri 6/69:12 amCUN - DSM

2 stops32h 06mMultiple Airlines

Deal found 4/15

$413

Mon 5/125:27 pmDSM - CUN

1 stop19h 48mAmerican Airlines

Sat 5/172:40 pmCUN - DSM

1 stop9h 18mAmerican Airlines

Deal found 4/14

$439

Tue 6/37:01 amDSM - CUN

2 stops12h 02mDelta

Tue 6/108:35 amCUN - DSM

2 stops14h 28mDelta

Deal found 4/14

$453

Sat 6/212:25 pmDSM - CUN

1 stop5h 55mAeromexico

Wed 6/253:25 pmCUN - DSM

1 stop7h 38mAeromexico

Deal found 4/13

$513

Mon 4/285:10 pmDSM - CUN

2 stops16h 54mUnited Airlines

Mon 5/53:46 pmCUN - DSM

1 stop7h 53mUnited Airlines

Deal found 4/14

$514

Sun 7/66:00 amDSM - CUN

1 stop7h 15mSouthwest

Sun 7/131:40 pmCUN - DSM

2 stops10h 25mSouthwest

Deal found 4/15

$639

Thu 5/2910:59 amDSM - CUN

3 stops30h 28mWestJet

Thu 6/56:30 pmCUN - DSM

3 stops22h 36mWestJet

Deal found 4/14

$860

Thu 6/56:35 pmDSM - CUN

2 stops19h 40mLATAM Airlines

Sun 6/81:20 amCUN - DSM

2 stops21h 43mLATAM Airlines

Deal found 4/14

$2,441

Last-minute flights from Des Moines to Cancún
Discover last-minute flight deals from Des Moines to Cancún. Data last updated April 15, 2025 and is based on user searches.

Fri 4/255:29 pmDSM - CUN

1 stop18h 36mAmerican Airlines

Tue 4/291:20 pmCUN - DSM

1 stop8h 47mAmerican Airlines

Deal found 4/14

$484

Fri 4/256:47 pmDSM - CUN

2 stops17h 46mUnited Airlines

Tue 4/295:22 pmCUN - DSM

2 stops17h 18mUnited Airlines

Deal found 4/14

$569

Mon 4/285:10 pmDSM - CUN

2 stops16h 54mUnited Airlines

Mon 5/53:46 pmCUN - DSM

1 stop7h 53mUnited Airlines

Deal found 4/14

$514

Mon 5/125:27 pmDSM - CUN

1 stop19h 48mAmerican Airlines

Sat 5/172:40 pmCUN - DSM

1 stop9h 18mAmerican Airlines

Deal found 4/14

$439

Tue 5/137:01 amDSM - CUN

2 stops13h 28mDelta

Tue 5/208:31 amCUN - DSM

2 stops13h 59mDelta

Deal found 4/13

$453

Thu 5/292:15 pmDSM - CUN

1 stop6h 05mAeromexico

Thu 6/58:00 amCUN - DSM

1 stop9h 50mAeromexico

Deal found 4/15

$562

Thu 5/2910:59 amDSM - CUN

3 stops30h 28mWestJet

Thu 6/56:30 pmCUN - DSM

3 stops22h 36mWestJet

Deal found 4/14

$860

Fri 5/306:30 amDSM - CUN

2 stops25h 46mMultiple Airlines

Fri 6/69:12 amCUN - DSM

2 stops32h 06mMultiple Airlines

Deal found 4/15

$413

One-way flights from Des Moines to Cancún
Search for one-way flight options from Des Moines to Cancún. Find affordable one-way fares based on user searches. Data last updated April 15, 2025.

Sun 5/41:27 pmDSM - CUN

1 stop21h 47mMultiple Airlines

Deal found 4/15

$159

Fri 4/257:27 pmDSM - CUN

1 stop18h 53mFrontier

Deal found 4/15

$200

Thu 5/297:01 amDSM - CUN

2 stops13h 18mDelta

Deal found 4/14

$234

Sat 5/245:27 pmDSM - CUN

1 stop21h 32mAmerican Airlines

Deal found 4/14

$241

Thu 5/296:00 amDSM - CUN

1 stop16h 07mUnited Airlines

Deal found 4/14

$278

Cheapflights Fare Finder

Use the filters below to find and compare flights from Des Moines to Cancún that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Fri 5/30

6:30 am-8:16 am

2 stops25h 46m

Cancun

Fri 6/6

9:12 am-5:18 pm

2 stops32h 06m

$413

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Mon 5/12

5:27 pm-1:15 pm

1 stop19h 48m

Cancun

Sat 5/17

2:40 pm-11:58 pm

1 stop9h 18m

$439

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Tue 6/3

7:01 am-7:03 pm

2 stops12h 02m

Cancun

Tue 6/10

8:35 am-11:03 pm

2 stops14h 28m

$453

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Sat 6/21

2:25 pm-8:20 pm

1 stop5h 55m

Cancun

Wed 6/25

3:25 pm-11:03 pm

1 stop7h 38m

$513

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Mon 4/28

5:10 pm-10:04 am

2 stops16h 54m

Cancun

Mon 5/5

3:46 pm-11:39 pm

1 stop7h 53m

$514

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Thu 6/26

5:25 am-3:25 pm

2 stops10h 00m

Cancun

Mon 6/30

2:45 pm-11:50 pm

2 stops9h 05m

$676

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Thu 5/29

10:59 am-5:27 pm

3 stops30h 28m

Cancun

Thu 6/5

6:30 pm-5:06 pm

3 stops22h 36m

$860

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Thu 6/5

6:35 pm-2:15 pm

2 stops19h 40m

Cancun

Sun 6/8

1:20 am-11:03 pm

2 stops21h 43m

$2,441

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Sun 5/4

1:27 pm-11:14 am

1 stop21h 47m

$159

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Fri 4/25

7:27 pm-2:20 pm

1 stop18h 53m

$200

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/15

Showing 1-10 of 13 results

Compare providers for flights from Des Moines to Cancún

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Cancún in April.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy1 star	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*2 stars
eDreams	Price Accuracy3 stars	Trust Score*3 stars
AranGrant	Price Accuracy3 stars	Trust Score*3 stars
ScholarTrip	Price Accuracy3 stars	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Des Moines-Cancún flights, users find the pricing of AranGrant to be most consistent on Cheapflights vs. AranGrant Users can find the same prices on Des Moines-Cancún flight deals on Cheapflights vs. AranGrant >95% of the time. Price accuracy is based on data collected from Des Moines-Cancún flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Des Moines-Cancún flights, Cheapflights users trust AranGrant the most. AranGrant has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Cancún flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Cancún

Have a flexible travel schedule? Discover the best time to fly to Cancún from Des Moines with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Cancún

How far ahead should I book a flight from Des Moines to Cancún?

The best time to book flights from Des Moines to Cancún is 25 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Des Moines to Cancún?

Currently, January is the cheapest month in which you can book a flight from Des Moines to Cancún (average of $360). Flying from Des Moines to Cancún in March is currently the most expensive (average of $492). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to CUN?

One of the essential ways to save on airfare from Des Moines to Cancún is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the evening could potentially save you up to 11% on airfare.

What is the cheapest day to fly from Des Moines to Cancún?

Travelers seeking maximum savings on their Des Moines to Cancún flight should consider departing on Tuesday afternoons when fares are most often at their lowest. Wednesday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Rainfall in Cancún by month

In terms of precipitation, rainfall in Cancún ranges from 1.1 - 11.1 inches per month. October is typically the wettest month, when rainfall can reach 11.1 in. April is typically the driest time to visit Cancún when rainfall is around 1.1 in.

Temperature in Cancún by month

If weather is an important factor for your trip to Cancún, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 86.0 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 75.2 F).

Reviews of airlines servicing Cancún

To help decide which airline to fly from Des Moines to Cancún, see what other customers have to say about Southwest, Delta and LATAM Airlines. In addition to providing an overall rating, users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Southwest

8.0

Very good

4,279 reviews

Reviews

1 / 20

8.0

Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.

Southwest

8.0

Very good

4,279 reviews

Southwest

8.0

Very good

4,279 reviews

Reviews

1 / 20

8.0

Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.

Delta

8.0

Very good

7,917 reviews

Southwest

8.0

Very good

4,279 reviews

Reviews

1 / 20

8.0

Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.

LATAM Airlines

7.5

Good

1,758 reviews

Southwest

8.0

Very good

4,279 reviews

Reviews

1 / 20

8.0

Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.

Aeromexico

7.5

Good

1,698 reviews

Southwest

8.0

Very good

4,279 reviews

Reviews

1 / 20

8.0

Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.

United Airlines

7.4

Good

8,658 reviews

Southwest

8.0

Very good

4,279 reviews

Reviews

1 / 20

8.0

Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.

Related info for your journey

What are the cheapest airlines flying from Des Moines to Cancún round-trip?
According to our current data, American Airlines ($439), Delta ($453), and Aeromexico ($513) offers the cheapest pricing from Des Moines to Cancún. American Airlines is priced at 24% lower than the current average price of a flight leaving 3 months from now.
What are the cheapest airlines to fly from Des Moines to Cancún one-way?
$200 is the cheapest one-way deal found within the past few days, from Frontier. You may also be able to find cheap deals on Delta and American Airlines, with prices starting from $234 and $241, respectively.
Can I find deals for flights from Des Moines to Cancún that include hotel bookings?
Yes. In addition to deals on Des Moines to Cancún flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Des Moines to Cancún?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Cancún.
Can I find deals for business class flights from Des Moines to Cancún?
Yes. Cheapflights offers flight deals from Des Moines to Cancún by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Des Moines to Cancún?
Currently, January is the cheapest month in which you can book a flight from Des Moines to Cancún (average of $360). Flying from Des Moines to Cancún in March is currently the most expensive (average of $492). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Puerto Aventuras

Punta Sam

Holbox

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for Des Moines to Cancún

Cedar Rapids to Cancún flights

Omaha to Cancún flights

Des Moines to Cozumel flights

Cedar Rapids to Cozumel flights

Omaha to Cozumel flights

Moline to Cancún flights

Moline to Cozumel flights

Waterloo to Cancún flights

Sioux City to Cozumel flights

La Crosse to Cancún flights

Sioux City to Cancún flights

Dubuque to Cancún flights

Other flights to Cancún

Top 5 airlines flying from Des Moines to Cancún

Airline	Cheapest	Average	Flexibility	On-time
Aeromexico	Cheapest$350	Average$498	FlexibilityNo cancel fee	On-timeN/A
Delta	Cheapest$409	Average$529	FlexibilityNo cancel fee	On-timeN/A
United Airlines	Cheapest$449	Average$574	FlexibilityNo cancel fee	On-time69%
American Airlines	Cheapest$452	Average$588	FlexibilityNo cancel fee	On-time71%
Southwest	Cheapest$460	Average$690	FlexibilityNo cancel fee	On-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.

$159+ Cheap flights from Des Moines (DSM) to Cancún (CUN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/4. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Des Moines to Cancún with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Des Moines to Cancún

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Des Moines to Cancún

Cheapest flights from Des Moines to CancúnExplore the most affordable flight options available from Des Moines to Cancún. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 15, 2025.

Explore the most affordable flight options available from Des Moines to Cancún. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 15, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Des Moines to Cancún that are best for you.

Compare providers for flights from Des Moines to Cancún

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Cancún in April.

Best time to book a flight from Des Moines to Cancún

Have a flexible travel schedule? Discover the best time to fly to Cancún from Des Moines with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Cancún

How far ahead should I book a flight from Des Moines to Cancún?

Use this chart to determine the optimal time to book a round-trip flight from Des Moines to Cancún. Price data was last updated on April 11, 2025.

What is the cheapest month to book a flight from Des Moines to Cancún?

What is the cheapest time of day to fly from DSM to CUN?

Find hourly flight availability from Des Moines to Cancún. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 15, 2025.

What is the cheapest day to fly from Des Moines to Cancún?

Use this chart to determine the cheapest time to fly round-trip from Des Moines to Cancún. Price data was last updated on December 16, 2024.

Rainfall in Cancún by month

Plan your trip to Cancún by taking into account the average rainfall totals by month.

Temperature in Cancún by month

Plan your trip to Cancún by taking into account the average temperature totals by month.

Reviews of airlines servicing Cancún

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Cancún. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines flying from Des Moines to Cancún round-trip?

What are the cheapest airlines to fly from Des Moines to Cancún one-way?

Can I find deals for flights from Des Moines to Cancún that include hotel bookings?

How can I find direct flights from Des Moines to Cancún?

Can I find deals for business class flights from Des Moines to Cancún?

What is the cheapest month to book a flight from Des Moines to Cancún?

Traveling to a place near Des Moines?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Des Moines to Cancún

See prices for flight routes from nearby airports that may be better suited for you.

Top 5 airlines flying from Des Moines to Cancún

100% Free

Book with Flexibility

Travel Smart

Cheapest flights from Des Moines to Cancún
Explore the most affordable flight options available from Des Moines to Cancún. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 15, 2025.