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$85+ Cheap flights from South Carolina to Buffalo (BUF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/16. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — BUF
Apr 2 — Apr 91
Wed 4/2
Wed 4/9
1 adult, Economy
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Cheap flight deals from South Carolina to Buffalo

Keep the following information in mind while searching for South Carolina to Buffalo flight deals. Data was last updated March 28, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$169
(American Airlines)

One-way from

$85
(American Airlines)

Popular in

February

Cheapest in

September

Average price

$361
Provider with most accurate pricing for Myrtle Beach Intl-Buffalo flight deals.
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From South Carolina to Buffalo
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One-way flight from South Carolina to Buffalo
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Highest demand for flights based on searches. 7% potential increase in price ($26 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).
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Average for round-trip flights in March 2025
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Find flight deals from South Carolina to Buffalo

Cheapest flights from South Carolina to Buffalo
Explore the most affordable flight options available from South Carolina to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 28, 2025.

This American Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/1310:45 pmCLT - BUF
Nonstop1h 53mAmerican Airlines
Sun 6/156:34 amBUF - CLT
Nonstop1h 51mAmerican Airlines
Deal found 3/27$169
This Southwest deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/167:00 amCLT - BUF
1 stop3h 20mSouthwest
Sun 4/207:30 pmBUF - CLT
1 stop4h 45mSouthwest
Deal found 3/26$184
This CheapOair deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1510:36 pmCLT - BUF
1 stop19h 52mFrontier
Sun 5/187:28 pmBUF - CLT
1 stop13h 29mFrontier
Deal found 3/27$190
This Delta deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/137:29 pmCLT - BUF
1 stop5h 20mDelta
Sun 6/156:04 amBUF - CLT
1 stop4h 59mDelta
Deal found 3/26$197
This American Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/126:16 pmSAV - BUF
1 stop5h 56mAmerican Airlines
Tue 8/191:54 pmBUF - SAV
1 stop5h 18mAmerican Airlines
Deal found 3/27$199
This Southwest deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/17:15 amSAV - BUF
1 stop6h 25mSouthwest
Sun 5/46:25 amBUF - SAV
1 stop4h 55mSouthwest
Deal found 3/27$214
This Delta deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/286:49 pmGSP - BUF
1 stop4h 11mDelta
Thu 5/12:59 pmBUF - GSP
1 stop6h 39mDelta
Deal found 3/26$217
This Delta deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/176:59 pmSAV - BUF
1 stop4h 54mDelta
Mon 5/196:30 amBUF - SAV
1 stop4h 07mDelta
Deal found 3/28$217
This American Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/248:18 pmCHS - BUF
1 stop4h 13mAmerican Airlines
Wed 4/303:01 pmBUF - CHS
1 stop3h 59mAmerican Airlines
Deal found 3/26$218
This United Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/710:41 amCLT - BUF
2 stops8h 10mUnited Airlines
Tue 5/136:00 amBUF - CLT
1 stop3h 45mUnited Airlines
Deal found 3/26$221
This Delta deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/15:35 amCHS - BUF
1 stop5h 25mDelta
Sat 5/36:45 pmBUF - CHS
1 stop5h 13mDelta
Deal found 3/27$222
This Delta deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/166:50 pmCAE - BUF
1 stop5h 09mDelta
Tue 9/233:30 pmBUF - CAE
1 stop6h 23mDelta
Deal found 3/27$227

Cheapflights Fare Finder

Customize your flight search to find flights from South Carolina to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 28, 2025.
Use the filters below to find and compare flights from South Carolina to Buffalo that are best for you.

Fly from

South Carolina

Fly to

Buffalo

Route

Depart

Return

Price

CharlotteBuffalo

CLT - BUF

CLTBUF

Charlotte Douglas

Fri 6/13

10:45 pm-12:38 am

Nonstop1h 53m

Buffalo

Sun 6/15

6:34 am-8:25 am

Nonstop1h 51m

$169

CharlotteBuffalo

CLT - BUF

CLTBUF

Charlotte Douglas

Wed 4/16

7:00 am-10:20 am

1 stop3h 20m

Buffalo

Sun 4/20

7:30 pm-12:15 am

1 stop4h 45m

$184

CharlotteBuffalo

CLT - BUF

CLTBUF

Charlotte Douglas

Thu 5/15

10:36 pm-6:28 pm

1 stop19h 52m

Buffalo

Sun 5/18

7:28 pm-8:57 am

1 stop13h 29m

$190

CharlotteBuffalo

CLT - BUF

CLTBUF

Charlotte Douglas

Fri 6/13

7:29 pm-12:49 am

1 stop5h 20m

Buffalo

Sun 6/15

6:04 am-11:03 am

1 stop4h 59m

$197

SavannahBuffalo

SAV - BUF

SAVBUF

Savannah/Hilton Head

Tue 8/12

6:16 pm-12:12 am

1 stop5h 56m

Buffalo

Tue 8/19

1:54 pm-7:12 pm

1 stop5h 18m

$199

SavannahBuffalo

SAV - BUF

SAVBUF

Savannah/Hilton Head

Thu 5/1

7:15 am-1:40 pm

1 stop6h 25m

Buffalo

Sun 5/4

6:25 am-11:20 am

1 stop4h 55m

$214

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

Mon 4/28

6:49 pm-11:00 pm

1 stop4h 11m

Buffalo

Thu 5/1

2:59 pm-9:38 pm

1 stop6h 39m

$217

SavannahBuffalo

SAV - BUF

SAVBUF

Savannah/Hilton Head

Sat 5/17

6:59 pm-11:53 pm

1 stop4h 54m

Buffalo

Mon 5/19

6:30 am-10:37 am

1 stop4h 07m

$217

CharlestonBuffalo

CHS - BUF

CHSBUF

Charleston

Thu 4/24

8:18 pm-12:31 am

1 stop4h 13m

Buffalo

Wed 4/30

3:01 pm-7:00 pm

1 stop3h 59m

$218

CharlotteBuffalo

CLT - BUF

CLTBUF

Charlotte Douglas

Wed 5/7

10:41 am-6:51 pm

2 stops8h 10m

Buffalo

Tue 5/13

6:00 am-9:45 am

1 stop3h 45m

$221

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/26

Showing 1-10 of 49 results
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Best time to book a flight from South Carolina to Buffalo

Have a flexible travel schedule? Discover the best time to fly to Buffalo from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Buffalo

What is the cheapest month to book a flight from South Carolina to Buffalo?

Currently, January is the cheapest month in which you can book a flight from South Carolina to Buffalo (average of $256). Flying from South Carolina to Buffalo in December is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to BUF?

Find hourly flight availability from South Carolina to Buffalo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 28, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from South Carolina to Buffalo as you normally would.

Rainfall in Buffalo by month

Plan your trip to Buffalo by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Buffalo ranges from 2.5 - 4.0 inches per month. November is typically the wettest month, when rainfall can reach 4.0 in. February is typically the driest time to visit Buffalo when rainfall is around 2.5 in.

Temperature in Buffalo by month

Plan your trip to Buffalo by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Buffalo, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 71.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 24.8 F).

Reviews of airlines servicing Buffalo

Get insights into the airlines that provide service to Buffalo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Buffalo. Reviews last updated March 28, 2025.
To help decide which airline to fly from South Carolina to Buffalo, see what other customers have to say about Southwest, Delta and United Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
4,274 reviews

Entertainment

7.6

Boarding

8.2

Comfort

8.1

Crew

8.7

Food

7.1

Overall

8.1

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Southwest
8.1
Very good
4,274 reviews
Southwest
8.1
Very good
4,274 reviews

Entertainment

7.6

Boarding

8.2

Comfort

8.1

Crew

8.7

Food

7.1

Overall

8.1

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Delta
8.0
Very good
7,897 reviews
Southwest
8.1
Very good
4,274 reviews

Entertainment

7.6

Boarding

8.2

Comfort

8.1

Crew

8.7

Food

7.1

Overall

8.1

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
United Airlines
7.4
Good
8,603 reviews
Southwest
8.1
Very good
4,274 reviews

Entertainment

7.6

Boarding

8.2

Comfort

8.1

Crew

8.7

Food

7.1

Overall

8.1

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
JetBlue
7.3
Good
2,923 reviews
Southwest
8.1
Very good
4,274 reviews

Entertainment

7.6

Boarding

8.2

Comfort

8.1

Crew

8.7

Food

7.1

Overall

8.1

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.1
Very good
4,274 reviews

Entertainment

7.6

Boarding

8.2

Comfort

8.1

Crew

8.7

Food

7.1

Overall

8.1

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Buffalo from South Carolina?

    Most people fly into Buffalo (BUF) if they book a flight to Buffalo from South Carolina. Buffalo is conveniently located just 8.3 mi from Buffalo’s city center.

  • What are the cheapest airlines to fly from South Carolina to Buffalo one-way?

    $85 is the cheapest one-way deal found within the past few days, from American Airlines. You may also be able to find cheap deals on Southwest and Frontier, with prices starting from $90 and $98, respectively.

  • What are the most popular routes from South Carolina to Buffalo?

    The most popular flight routes from South Carolina to Buffalo are Charlotte Douglas - Buffalo, Columbia Metropolitan - Buffalo and Charleston - Buffalo.

  • Can I find deals for flights from South Carolina to Buffalo that include hotel bookings?

    Yes. In addition to deals on South Carolina to Buffalo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Buffalo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Buffalo.

  • Can I find deals for business class flights from South Carolina to Buffalo?

    Yes. Cheapflights offers flight deals from South Carolina to Buffalo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Buffalo?

    Currently, January is the cheapest month in which you can book a flight from South Carolina to Buffalo (average of $256). Flying from South Carolina to Buffalo in December is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near South Carolina?

Book flights to South Carolina if you plan to visit one of these locations
West Seneca
Williamsville
Amherst
Batavia
Orchard Park
Cheektowaga

Browse thousands of different options on Cheapflights for your next trip

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Top 5 airlines flying from South Carolina to Buffalo

Discover the top 5 airlines that operate flights from South Carolina to Buffalo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$197Average$352FlexibilityNo cancel feeOn-time71%
JetBlueCheapest$201Average$290FlexibilityNo cancel feeOn-time62%
United AirlinesCheapest$202Average$373FlexibilityNo cancel feeOn-time69%
DeltaCheapest$207Average$316FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$233Average$380FlexibilityNo cancel feeOn-time63%
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