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$91+ Cheap flights from Missouri to Buffalo (BUF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/3. Fares are subject to change and may not be available on all flights or dates of travel.
STL — BUF
Apr 29 — May 61
Tue 4/29
Tue 5/6
1 adult, Economy
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Cheap flight deals from Missouri to Buffalo

Keep the following information in mind while searching for Missouri to Buffalo flight deals. Data was last updated April 24, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$171
(American Airlines)

One-way from

$91
(American Airlines)

Popular in

November

Cheapest in

January

Average price

$416
Provider with most accurate pricing for Kansas City-Buffalo flight deals.
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Provider most trusted by Cheapflights users for Kansas City-Buffalo flights.
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From Missouri to Buffalo
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One-way flight from Missouri to Buffalo
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Highest demand for flights based on searches. 3% potential increase in price ($14 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from Missouri to Buffalo

Cheapest flights from Missouri to Buffalo
Explore the most affordable flight options available from Missouri to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 24, 2025.

This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/226:00 amSTL - BUF
1 stop10h 24mAmerican Airlines
Thu 5/293:00 pmBUF - STL
1 stop9h 51mAmerican Airlines
Deal found 4/23$171
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/235:00 amMCI - BUF
1 stop10h 10mAmerican Airlines
Wed 6/255:04 pmBUF - MCI
1 stop7h 55mAmerican Airlines
Deal found 4/23$171
This Booking.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/85:45 pmSTL - BUF
1 stop14h 16mFrontier
Mon 5/129:51 amBUF - STL
1 stop15h 15mFrontier
Deal found 4/23$208
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/266:40 amSTL - BUF
1 stop4h 30mDelta
Sun 6/296:30 amBUF - STL
1 stop4h 07mDelta
Deal found 4/23$251
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/83:20 pmSGF - BUF
1 stop5h 02mUnited Airlines
Mon 5/126:45 amBUF - SGF
1 stop5h 08mUnited Airlines
Deal found 4/23$259
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/276:36 pmMCI - BUF
1 stop14h 20mUnited Airlines
Mon 6/27:00 amBUF - MCI
1 stop17h 15mUnited Airlines
Deal found 4/23$263
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/205:48 pmMCI - BUF
1 stop3h 58mDelta
Wed 5/286:30 amBUF - MCI
1 stop4h 12mDelta
Deal found 4/23$271
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1510:39 amSTL - BUF
1 stop5h 16mUnited Airlines
Wed 5/216:00 amBUF - STL
2 stops7h 19mUnited Airlines
Deal found 4/23$292
This Southwest deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/235:45 pmSTL - BUF
1 stop5h 35mSouthwest
Mon 7/285:35 amBUF - STL
2 stops7h 45mSouthwest
Deal found 4/24$304
This Southwest deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/156:20 amMCI - BUF
1 stop8h 05mSouthwest
Sun 8/248:55 pmBUF - MCI
1 stop3h 55mSouthwest
Deal found 4/23$360

Cheapflights Fare Finder

Customize your flight search to find flights from Missouri to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2025.
Use the filters below to find and compare flights from Missouri to Buffalo that are best for you.

Fly from

Missouri

Fly to

Buffalo

Route

Depart

Return

Price

St. LouisBuffalo

STL - BUF

STLBUF

Lambert-St Louis

Thu 5/22

6:00 am-5:24 pm

1 stop10h 24m

Buffalo

Thu 5/29

3:00 pm-11:51 pm

1 stop9h 51m

$171

Kansas CityBuffalo

MCI - BUF

MCIBUF

Kansas City

Mon 6/23

5:00 am-4:10 pm

1 stop10h 10m

Buffalo

Wed 6/25

5:04 pm-11:59 pm

1 stop7h 55m

$171

St. LouisBuffalo

STL - BUF

STLBUF

Lambert-St Louis

Thu 5/8

5:45 pm-9:01 am

1 stop14h 16m

Buffalo

Mon 5/12

9:51 am-12:06 am

1 stop15h 15m

$208

St. LouisBuffalo

STL - BUF

STLBUF

Lambert-St Louis

Thu 6/26

6:40 am-12:10 pm

1 stop4h 30m

Buffalo

Sun 6/29

6:30 am-9:37 am

1 stop4h 07m

$251

SpringfieldBuffalo

SGF - BUF

SGFBUF

Springfield-Branson

Thu 5/8

3:20 pm-9:22 pm

1 stop5h 02m

Buffalo

Mon 5/12

6:45 am-10:53 am

1 stop5h 08m

$259

Kansas CityBuffalo

MCI - BUF

MCIBUF

Kansas City

Tue 5/27

6:36 pm-9:56 am

1 stop14h 20m

Buffalo

Mon 6/2

7:00 am-11:15 pm

1 stop17h 15m

$263

Kansas CityBuffalo

MCI - BUF

MCIBUF

Kansas City

Tue 5/20

5:48 pm-10:46 pm

1 stop3h 58m

Buffalo

Wed 5/28

6:30 am-9:42 am

1 stop4h 12m

$271

St. LouisBuffalo

STL - BUF

STLBUF

Lambert-St Louis

Thu 5/15

10:39 am-4:55 pm

1 stop5h 16m

Buffalo

Wed 5/21

6:00 am-12:19 pm

2 stops7h 19m

$292

St. LouisBuffalo

STL - BUF

STLBUF

Lambert-St Louis

Wed 7/23

5:45 pm-12:20 am

1 stop5h 35m

Buffalo

Mon 7/28

5:35 am-12:20 pm

2 stops7h 45m

$304

Kansas CityBuffalo

MCI - BUF

MCIBUF

Kansas City

Fri 8/15

6:20 am-3:25 pm

1 stop8h 05m

Buffalo

Sun 8/24

8:55 pm-11:50 pm

1 stop3h 55m

$360

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/23

Showing 1-10 of 20 results
1
2

Best time to book a flight from Missouri to Buffalo

Have a flexible travel schedule? Discover the best time to fly to Buffalo from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Buffalo

What is the cheapest month to book a flight from Missouri to Buffalo?

Currently, January is the cheapest month in which you can book a flight from Missouri to Buffalo (average of $256). Flying from Missouri to Buffalo in December is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to BUF?

Find hourly flight availability from Missouri to Buffalo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 24, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Missouri to Buffalo as you normally would.

Rainfall in Buffalo by month

Plan your trip to Buffalo by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Buffalo ranges from 2.5 - 4.0 inches per month. November is typically the wettest month, when rainfall can reach 4.0 in. February is typically the driest time to visit Buffalo when rainfall is around 2.5 in.

Temperature in Buffalo by month

Plan your trip to Buffalo by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Buffalo, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 71.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 24.8 F).

Reviews of airlines servicing Buffalo

Get insights into the airlines that provide service to Buffalo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Buffalo. Reviews last updated April 24, 2025.
Read through reviews of airlines operating flights from Missouri to Buffalo, such as Southwest, Delta and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,286 reviews

Crew

8.6

Food

7.1

Boarding

8.2

Entertainment

7.6

Overall

8.0

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
Southwest
8.0
Very good
4,286 reviews
Southwest
8.0
Very good
4,286 reviews

Crew

8.6

Food

7.1

Boarding

8.2

Entertainment

7.6

Overall

8.0

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
Delta
8.0
Very good
7,920 reviews
Southwest
8.0
Very good
4,286 reviews

Crew

8.6

Food

7.1

Boarding

8.2

Entertainment

7.6

Overall

8.0

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
United Airlines
7.4
Good
8,685 reviews
Southwest
8.0
Very good
4,286 reviews

Crew

8.6

Food

7.1

Boarding

8.2

Entertainment

7.6

Overall

8.0

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,286 reviews

Crew

8.6

Food

7.1

Boarding

8.2

Entertainment

7.6

Overall

8.0

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
Frontier
6.0
Okay
3,283 reviews
Southwest
8.0
Very good
4,286 reviews

Crew

8.6

Food

7.1

Boarding

8.2

Entertainment

7.6

Overall

8.0

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!

Related info for your journey

Find useful and relevant information for your journey from Missouri to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Buffalo from Missouri?

    Most people fly into Buffalo (BUF) if they book a flight to Buffalo from Missouri. Buffalo is conveniently located just 8.3 mi from Buffalo’s city center.

  • What are the cheapest airlines to fly from Missouri to Buffalo one-way?

    One-way options have recently been found by users for as low as $91 on American Airlines. Other airlines that offer cheap prices include Delta from $126 and Southwest from $173 one-way.

  • What are the most popular routes from Missouri to Buffalo?

    While some choose either Kansas City - Buffalo or Columbia Regional - Buffalo, Lambert-St Louis - Buffalo is the most popular route from Missouri to Buffalo.

  • Can I find deals for flights from Missouri to Buffalo that include hotel bookings?

    Yes. In addition to deals on Missouri to Buffalo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Buffalo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Buffalo.

  • Can I find deals for business class flights from Missouri to Buffalo?

    Yes. Cheapflights offers flight deals from Missouri to Buffalo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Buffalo?

    Currently, January is the cheapest month in which you can book a flight from Missouri to Buffalo (average of $256). Flying from Missouri to Buffalo in December is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Missouri?

Book flights to Missouri if you plan to visit one of these locations
West Seneca
Williamsville
Amherst
Batavia
Orchard Park
Cheektowaga

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Top 4 airlines flying from Missouri to Buffalo

Discover the top 4 airlines that operate flights from Missouri to Buffalo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$179Average$433FlexibilityNo cancel feeOn-time69%
DeltaCheapest$200Average$388FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$226Average$431FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$306Average$402FlexibilityNo cancel feeOn-time63%

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