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$117+ Cheap flights from Missouri to Buffalo (BUF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/3. Fares are subject to change and may not be available on all flights or dates of travel.
STL — BUF
Apr 2 — Apr 91
Wed 4/2
Wed 4/9
1 adult, Economy
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Cheap flight deals from Missouri to Buffalo

Keep the following information in mind while searching for Missouri to Buffalo flight deals. Data was last updated March 28, 2025.

Round-trip from

$199
(American Airlines)

One-way from

$117
(Trip.com)
From Missouri to Buffalo
Search Deals
One-way flight from Missouri to Buffalo
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Find flight deals from Missouri to Buffalo

Cheapest flights from Missouri to Buffalo
Explore the most affordable flight options available from Missouri to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 28, 2025.

This American Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/175:47 amSGF - BUF
1 stop3h 52mAmerican Airlines
Wed 9/245:27 amBUF - SGF
1 stop7h 01mAmerican Airlines
Deal found 3/27$199
This United Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/176:00 amSGF - BUF
2 stops9h 47mUnited Airlines
Wed 9/2410:57 amBUF - SGF
1 stop7h 48mUnited Airlines
Deal found 3/27$233
This Booking.com deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/25:55 pmSTL - BUF
1 stop15h 53mFrontier
Sun 5/49:51 amBUF - STL
1 stop15h 15mFrontier
Deal found 3/27$238
This Delta deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/253:30 pmSTL - BUF
1 stop6h 32mDelta
Mon 4/286:00 amBUF - STL
1 stop6h 45mDelta
Deal found 3/28$307
This American Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/126:00 amSTL - BUF
1 stop5h 03mAmerican Airlines
Sun 6/155:20 amBUF - STL
1 stop3h 45mAmerican Airlines
Deal found 3/27$317
This American Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/294:24 pmMCI - BUF
1 stop4h 44mAmerican Airlines
Sun 8/315:08 pmBUF - MCI
1 stop6h 14mAmerican Airlines
Deal found 3/27$332
This Southwest deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/136:20 amMCI - BUF
1 stop4h 40mSouthwest
Sun 8/176:00 amBUF - MCI
2 stops6h 05mSouthwest
Deal found 3/28$337
This United Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/23:43 pmSTL - BUF
1 stop4h 39mUnited Airlines
Sun 5/46:00 amBUF - STL
2 stops7h 20mUnited Airlines
Deal found 3/27$342
This Southwest deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/135:25 amSTL - BUF
1 stop4h 00mSouthwest
Mon 6/1612:35 pmBUF - STL
2 stops7h 35mSouthwest
Deal found 3/27$352
This United Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/295:47 pmMCI - BUF
1 stop4h 39mUnited Airlines
Sun 8/316:00 amBUF - MCI
2 stops9h 21mUnited Airlines
Deal found 3/26$407
This Delta deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/173:54 pmSGF - BUF
2 stops6h 16mDelta
Mon 6/236:04 amBUF - SGF
2 stops12h 59mDelta
Deal found 3/26$649

Cheapflights Fare Finder

Customize your flight search to find flights from Missouri to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 28, 2025.
Use the filters below to find and compare flights from Missouri to Buffalo that are best for you.

Fly from

Missouri

Fly to

Buffalo

Route

Depart

Return

Price

St. LouisBuffalo

STL - BUF

STLBUF

Lambert-St Louis

Fri 5/2

5:55 pm-10:48 am

1 stop15h 53m

Buffalo

Sun 5/4

9:51 am-12:06 am

1 stop15h 15m

$238

SpringfieldBuffalo

SGF - BUF

SGFBUF

Springfield-Branson

Thu 4/10

11:25 am-4:55 pm

1 stop4h 30m

Buffalo

Mon 4/14

5:51 pm-9:56 pm

1 stop5h 05m

$259

SpringfieldBuffalo

SGF - BUF

SGFBUF

Springfield-Branson

Tue 6/17

2:10 pm-7:51 pm

1 stop4h 41m

Buffalo

Mon 6/23

6:34 am-12:36 pm

1 stop7h 02m

$269

St. LouisBuffalo

STL - BUF

STLBUF

Lambert-St Louis

Fri 4/25

3:30 pm-11:02 pm

1 stop6h 32m

Buffalo

Mon 4/28

6:00 am-11:45 am

1 stop6h 45m

$307

St. LouisBuffalo

STL - BUF

STLBUF

Lambert-St Louis

Thu 6/12

6:00 am-12:03 pm

1 stop5h 03m

Buffalo

Sun 6/15

5:20 am-8:05 am

1 stop3h 45m

$317

Kansas CityBuffalo

MCI - BUF

MCIBUF

Kansas City

Fri 8/29

4:24 pm-10:08 pm

1 stop4h 44m

Buffalo

Sun 8/31

5:08 pm-10:22 pm

1 stop6h 14m

$332

Kansas CityBuffalo

MCI - BUF

MCIBUF

Kansas City

Thu 8/21

7:25 am-3:50 pm

2 stops7h 25m

Buffalo

Sat 8/30

12:15 pm-4:45 pm

1 stop5h 30m

$337

St. LouisBuffalo

STL - BUF

STLBUF

Lambert-St Louis

Fri 5/2

3:43 pm-9:22 pm

1 stop4h 39m

Buffalo

Sun 5/4

6:00 am-12:20 pm

2 stops7h 20m

$342

St. LouisBuffalo

STL - BUF

STLBUF

Lambert-St Louis

Fri 6/13

5:25 am-10:25 am

1 stop4h 00m

Buffalo

Mon 6/16

12:35 pm-7:10 pm

2 stops7h 35m

$352

Kansas CityBuffalo

MCI - BUF

MCIBUF

Kansas City

Fri 8/29

5:47 pm-11:26 pm

1 stop4h 39m

Buffalo

Sun 8/31

6:00 am-2:21 pm

2 stops9h 21m

$407

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/27

Showing 1-10 of 21 results
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2
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Best time to book a flight from Missouri to Buffalo

Have a flexible travel schedule? Discover the best time to fly to Buffalo from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Buffalo

What is the cheapest month to book a flight from Missouri to Buffalo?

Currently, January is the cheapest month in which you can book a flight from Missouri to Buffalo (average of $256). Flying from Missouri to Buffalo in December is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to BUF?

Find hourly flight availability from Missouri to Buffalo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 28, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Missouri to Buffalo as you normally would.

Rainfall in Buffalo by month

Plan your trip to Buffalo by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Buffalo ranges from 2.5 - 4.0 inches per month. November is typically the wettest month, when rainfall can reach 4.0 in. February is typically the driest time to visit Buffalo when rainfall is around 2.5 in.

Temperature in Buffalo by month

Plan your trip to Buffalo by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Buffalo, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 71.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 24.8 F).

Reviews of airlines servicing Buffalo

Get insights into the airlines that provide service to Buffalo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Buffalo. Reviews last updated March 28, 2025.
Read through reviews of airlines operating flights from Missouri to Buffalo, such as Southwest, Delta and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
4,274 reviews

Comfort

8.1

Crew

8.7

Food

7.1

Entertainment

7.6

Boarding

8.2

Overall

8.1

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Southwest
8.1
Very good
4,274 reviews
Southwest
8.1
Very good
4,274 reviews

Comfort

8.1

Crew

8.7

Food

7.1

Entertainment

7.6

Boarding

8.2

Overall

8.1

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Delta
8.0
Very good
7,897 reviews
Southwest
8.1
Very good
4,274 reviews

Comfort

8.1

Crew

8.7

Food

7.1

Entertainment

7.6

Boarding

8.2

Overall

8.1

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
United Airlines
7.4
Good
8,603 reviews
Southwest
8.1
Very good
4,274 reviews

Comfort

8.1

Crew

8.7

Food

7.1

Entertainment

7.6

Boarding

8.2

Overall

8.1

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.1
Very good
4,274 reviews

Comfort

8.1

Crew

8.7

Food

7.1

Entertainment

7.6

Boarding

8.2

Overall

8.1

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Frontier
6.0
Okay
3,271 reviews
Southwest
8.1
Very good
4,274 reviews

Comfort

8.1

Crew

8.7

Food

7.1

Entertainment

7.6

Boarding

8.2

Overall

8.1

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Buffalo from Missouri?

    Most people fly into Buffalo (BUF) if they book a flight to Buffalo from Missouri. Buffalo is conveniently located just 8.3 mi from Buffalo’s city center.

  • What are the cheapest airlines to fly from Missouri to Buffalo one-way?

    One-way options have recently been found by users for as low as $117 on Frontier. Other airlines that offer cheap prices include Delta from $119 and United Airlines from $140 one-way.

  • What are the most popular routes from Missouri to Buffalo?

    While some choose either Kansas City - Buffalo or Springfield-Branson - Buffalo, Lambert-St Louis - Buffalo is the most popular route from Missouri to Buffalo.

  • Can I find deals for flights from Missouri to Buffalo that include hotel bookings?

    Yes. In addition to deals on Missouri to Buffalo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Buffalo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Buffalo.

  • Can I find deals for business class flights from Missouri to Buffalo?

    Yes. Cheapflights offers flight deals from Missouri to Buffalo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Buffalo?

    Currently, January is the cheapest month in which you can book a flight from Missouri to Buffalo (average of $256). Flying from Missouri to Buffalo in December is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Missouri?

Book flights to Missouri if you plan to visit one of these locations
West Seneca
Williamsville
Amherst
Batavia
Orchard Park
Cheektowaga

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Top 4 airlines flying from Missouri to Buffalo

Discover the top 4 airlines that operate flights from Missouri to Buffalo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$200Average$391FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$248Average$438FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$298Average$430FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$306Average$401FlexibilityNo cancel feeOn-time63%
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