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$148+ Cheap flights from Missouri to Buffalo (BUF)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/7. Fares are subject to change and may not be available on all flights or dates of travel.
STL — BUF
Feb 25 — Mar 41
Tue 2/25
Tue 3/4
1 adult, Economy
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Cheap flight deals from Missouri to Buffalo

Keep the following information in mind while searching for Missouri to Buffalo flight deals. Data was last updated February 20, 2025.

Round-trip from

$148
(Mytrip)
From Missouri to Buffalo
Search Deals

Find flight deals from Missouri to Buffalo

Cheapest flights from Missouri to Buffalo
Explore the most affordable flight options available from Missouri to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 20, 2025.

This Mytrip deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/75:24 pmSTL - BUF
1 stop16h 00mFrontier
Tue 3/1111:24 amBUF - STL
1 stop13h 25mFrontier
Deal found 2/20$148
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/612:15 pmSGF - BUF
1 stop4h 29mDelta
Mon 3/1012:17 pmBUF - SGF
1 stop6h 52mDelta
Deal found 2/19$259
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/65:36 amSGF - BUF
2 stops8h 52mAmerican Airlines
Mon 3/103:46 pmBUF - SGF
2 stops9h 06mAmerican Airlines
Deal found 2/19$269
This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/611:00 amMCI - BUF
1 stop5h 44mDelta
Wed 3/127:48 pmBUF - MCI
1 stop19h 22mDelta
Deal found 2/20$291
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/75:06 amSTL - BUF
1 stop5h 08mAmerican Airlines
Tue 3/114:20 pmBUF - STL
2 stops6h 58mAmerican Airlines
Deal found 2/20$312
This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/236:50 amSTL - BUF
1 stop4h 20mDelta
Sat 3/295:48 pmBUF - STL
1 stop4h 52mDelta
Deal found 2/20$317
This Southwest deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/315:30 pmMCI - BUF
1 stop6h 25mSouthwest
Fri 4/45:50 pmBUF - MCI
2 stops7h 50mSouthwest
Deal found 2/19$322
This Southwest deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/314:55 pmSTL - BUF
2 stops6h 10mSouthwest
Fri 4/49:10 pmBUF - STL
2 stops13h 55mSouthwest
Deal found 2/19$323
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/63:55 pmMCI - BUF
1 stop7h 15mAmerican Airlines
Wed 3/124:20 pmBUF - MCI
2 stops7h 10mAmerican Airlines
Deal found 2/20$333
This United Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/263:20 pmSGF - BUF
1 stop4h 35mUnited Airlines
Wed 3/55:36 pmBUF - SGF
1 stop5h 08mUnited Airlines
Deal found 2/19$360
This United Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/710:03 amSTL - BUF
1 stop5h 47mUnited Airlines
Tue 3/116:00 amBUF - STL
1 stop6h 22mUnited Airlines
Deal found 2/20$378
This United Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/712:15 pmMCI - BUF
1 stop5h 47mUnited Airlines
Tue 3/112:00 pmBUF - MCI
1 stop6h 34mUnited Airlines
Deal found 2/20$388

Find flights from Missouri to Buffalo within your budget

Customize your flight search to find flights from Missouri to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.

Fly from

Missouri

Fly to

Buffalo

Route

Depart

Return

Price

St. LouisBuffalo

STL - BUF

STLBUF

Lambert-St Louis

Fri 3/7

5:24 pm-10:24 am

1 stop16h 00m

Buffalo

Tue 3/11

11:24 am-11:49 pm

1 stop13h 25m

$148

SpringfieldBuffalo

SGF - BUF

SGFBUF

Springfield-Branson

Thu 3/6

12:15 pm-5:44 pm

1 stop4h 29m

Buffalo

Mon 3/10

12:17 pm-6:09 pm

1 stop6h 52m

$259

SpringfieldBuffalo

SGF - BUF

SGFBUF

Springfield-Branson

Thu 3/6

5:36 am-3:28 pm

2 stops8h 52m

Buffalo

Mon 3/10

3:46 pm-11:52 pm

2 stops9h 06m

$269

Kansas CityBuffalo

MCI - BUF

MCIBUF

Kansas City

Thu 3/6

11:00 am-5:44 pm

1 stop5h 44m

Buffalo

Wed 3/12

7:48 pm-2:10 pm

1 stop19h 22m

$291

St. LouisBuffalo

STL - BUF

STLBUF

Lambert-St Louis

Fri 3/7

5:06 am-11:14 am

1 stop5h 08m

Buffalo

Tue 3/11

4:20 pm-10:18 pm

2 stops6h 58m

$312

St. LouisBuffalo

STL - BUF

STLBUF

Lambert-St Louis

Sun 3/23

6:50 am-12:10 pm

1 stop4h 20m

Buffalo

Sat 3/29

5:48 pm-9:40 pm

1 stop4h 52m

$317

Kansas CityBuffalo

MCI - BUF

MCIBUF

Kansas City

Mon 3/31

5:30 pm-12:55 am

1 stop6h 25m

Buffalo

Fri 4/4

5:50 pm-12:40 am

2 stops7h 50m

$322

St. LouisBuffalo

STL - BUF

STLBUF

Lambert-St Louis

Mon 3/31

4:55 pm-12:05 am

2 stops6h 10m

Buffalo

Fri 4/4

9:10 pm-10:05 am

2 stops13h 55m

$323

Kansas CityBuffalo

MCI - BUF

MCIBUF

Kansas City

Thu 3/6

3:55 pm-12:10 am

1 stop7h 15m

Buffalo

Wed 3/12

4:20 pm-10:30 pm

2 stops7h 10m

$333

St. LouisBuffalo

STL - BUF

STLBUF

Lambert-St Louis

Fri 3/7

10:03 am-4:50 pm

1 stop5h 47m

Buffalo

Tue 3/11

6:00 am-11:22 am

1 stop6h 22m

$378

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/19

Showing 1-10 of 18 results
1
2

Best time to book a flight from Missouri to Buffalo

Have a flexible travel schedule? Discover the best time to fly to Buffalo from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Missouri to Buffalo

Get recent, data-driven insights about flights from Missouri to Buffalo including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Missouri to Buffalo?

Currently, January is the cheapest month in which you can book a flight from Missouri to Buffalo (average of $256). Flying from Missouri to Buffalo in December is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to BUF?

Find hourly flight availability from Missouri to Buffalo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 20, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Missouri to Buffalo as you normally would.

Rainfall in Buffalo by month

Plan your trip to Buffalo by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Buffalo ranges from 2.5 - 4.0 inches per month. November is typically the wettest month, when rainfall can reach 4.0 in. February is typically the driest time to visit Buffalo when rainfall is around 2.5 in.

Temperature in Buffalo by month

Plan your trip to Buffalo by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Buffalo, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 71.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 24.8 F).

Reviews of airlines servicing Buffalo

Get insights into the airlines that provide service to Buffalo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Buffalo. Reviews last updated February 20, 2025.
Read through reviews of airlines operating flights from Missouri to Buffalo, such as Southwest, Delta and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
4,411 reviews

Food

7.1

Boarding

8.2

Comfort

8.1

Overall

8.1

Crew

8.7

Entertainment

7.6

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Southwest
8.1
Very good
4,411 reviews
Southwest
8.1
Very good
4,411 reviews

Food

7.1

Boarding

8.2

Comfort

8.1

Overall

8.1

Crew

8.7

Entertainment

7.6

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Delta
8.0
Very good
8,219 reviews
Southwest
8.1
Very good
4,411 reviews

Food

7.1

Boarding

8.2

Comfort

8.1

Overall

8.1

Crew

8.7

Entertainment

7.6

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

United Airlines
7.4
Good
8,765 reviews
Southwest
8.1
Very good
4,411 reviews

Food

7.1

Boarding

8.2

Comfort

8.1

Overall

8.1

Crew

8.7

Entertainment

7.6

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

American Airlines
7.2
Good
10,000 reviews
Southwest
8.1
Very good
4,411 reviews

Food

7.1

Boarding

8.2

Comfort

8.1

Overall

8.1

Crew

8.7

Entertainment

7.6

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Frontier
6.0
Okay
3,355 reviews
Southwest
8.1
Very good
4,411 reviews

Food

7.1

Boarding

8.2

Comfort

8.1

Overall

8.1

Crew

8.7

Entertainment

7.6

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Buffalo from Missouri?

    Most people fly into Buffalo (BUF) if they book a flight to Buffalo from Missouri. Buffalo is conveniently located just 8.3 mi from Buffalo’s city center.

  • What are the cheapest airlines to fly from Missouri to Buffalo one-way?

    One-way options have recently been found by users for as low as $149 on Delta. Other airlines that offer cheap prices include American Airlines from $154 and United Airlines from $224 one-way.

  • What are the most popular routes from Missouri to Buffalo?

    While some choose either Kansas City - Buffalo or Springfield-Branson - Buffalo, Lambert-St Louis - Buffalo is the most popular route from Missouri to Buffalo.

  • Can I find deals for flights from Missouri to Buffalo that include hotel bookings?

    Yes. In addition to deals on Missouri to Buffalo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Buffalo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Buffalo.

  • Can I find deals for business class flights from Missouri to Buffalo?

    Yes. Cheapflights offers flight deals from Missouri to Buffalo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Buffalo?

    Currently, January is the cheapest month in which you can book a flight from Missouri to Buffalo (average of $256). Flying from Missouri to Buffalo in December is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Missouri?

Book flights to Missouri if you plan to visit one of these locations
West Seneca
Williamsville
Amherst
Batavia
Orchard Park
Cheektowaga

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Alternative routes for Missouri to Buffalo

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Top 6 airlines flying from Missouri to Buffalo

Discover the top 6 airlines that operate flights from Missouri to Buffalo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$137Average$233FlexibilityNo cancel feeOn-time62%
JetBlueCheapest$197Average$410FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$248Average$452FlexibilityNo cancel feeOn-time71%
DeltaCheapest$261Average$407FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$298Average$445FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$306Average$411FlexibilityNo cancel feeOn-time63%
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