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$110+ Cheap flights from Missouri to Buffalo (BUF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/25. Fares are subject to change and may not be available on all flights or dates of travel.
STL — BUF
Jan 22 — Jan 291
Wed 1/22
Wed 1/29
1 adult, Economy
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Cheap flight deals from Missouri to Buffalo

Discover tips and strategies to find the most affordable flight options for your journey from Missouri (USMO) to Buffalo (BUF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 17, 2025.

Round-trip from

$200
(FlightHub)

One-way from

$110
(CheapOair)
From Missouri to Buffalo
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One-way flight from Missouri to Buffalo
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Find flight deals from Missouri to Buffalo

Cheapest flights from Missouri to Buffalo
Explore the most affordable flight options available from Missouri to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 17, 2025.

This FlightHub deal was found by Cheapflights users on 1/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/295:05 pmSTL - BUF
1 stop21h 02mFrontier
Fri 2/215:07 pmBUF - STL
1 stop7h 36mFrontier
Deal found 1/16$200
This Delta deal was found by Cheapflights users on 1/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/206:00 amSTL - BUF
1 stop4h 18mDelta
Sun 2/236:22 amBUF - STL
1 stop4h 14mDelta
Deal found 1/16$347
This United Airlines deal was found by Cheapflights users on 1/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/131:27 pmSTL - BUF
1 stop6h 04mUnited Airlines
Sat 10/186:00 amBUF - STL
2 stops7h 20mUnited Airlines
Deal found 1/16$352
This Delta deal was found by Cheapflights users on 1/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/216:00 amMCI - BUF
1 stop6h 35mDelta
Sun 2/236:22 amBUF - MCI
1 stop4h 41mDelta
Deal found 1/16$367
This United Airlines deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/256:00 amMCI - BUF
2 stops6h 46mUnited Airlines
Sun 6/17:00 amBUF - MCI
1 stop4h 29mUnited Airlines
Deal found 1/15$372
This Southwest deal was found by Cheapflights users on 1/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/135:35 amSTL - BUF
1 stop6h 05mSouthwest
Mon 7/218:30 pmBUF - STL
1 stop4h 10mSouthwest
Deal found 1/16$407
This Southwest deal was found by Cheapflights users on 1/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/177:10 amMCI - BUF
2 stops8h 20mSouthwest
Mon 5/196:25 amBUF - MCI
2 stops6h 00mSouthwest
Deal found 1/16$417
This American Airlines deal was found by Cheapflights users on 1/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/235:45 amSTL - BUF
1 stop4h 04mAmerican Airlines
Sat 3/295:06 pmBUF - STL
1 stop6h 05mAmerican Airlines
Deal found 1/16$427
This American Airlines deal was found by Cheapflights users on 1/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/136:21 amMCI - BUF
2 stops8h 03mAmerican Airlines
Sun 2/1611:13 amBUF - MCI
1 stop7h 31mAmerican Airlines
Deal found 1/16$433
This American Airlines deal was found by Cheapflights users on 1/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/57:19 amSGF - BUF
1 stop4h 31mAmerican Airlines
Mon 6/98:00 amBUF - SGF
1 stop4h 20mAmerican Airlines
Deal found 1/16$462
This American Airlines deal was found by Cheapflights users on 1/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/144:26 pmCOU - BUF
1 stop19h 16mAmerican Airlines
Thu 2/2011:13 amBUF - COU
1 stop11h 11mAmerican Airlines
Deal found 1/16$568

Find flights from Missouri to Buffalo within your budget

Customize your flight search to find flights from Missouri to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 17, 2025.

Fly from

Any airport

Fly to

Any airport

Route

Depart

Return

Price

St. LouisBuffalo

STL - BUF

STLBUF

Lambert-St Louis

Wed 1/29

5:05 pm-3:07 pm

1 stop21h 02m

Buffalo

Fri 2/21

5:07 pm-11:43 pm

1 stop7h 36m

$200

St. LouisBuffalo

STL - BUF

STLBUF

Lambert-St Louis

Thu 2/20

6:00 am-11:18 am

1 stop4h 18m

Buffalo

Sun 2/23

6:22 am-9:36 am

1 stop4h 14m

$347

St. LouisBuffalo

STL - BUF

STLBUF

Lambert-St Louis

Sat 2/1

2:55 pm-9:10 pm

1 stop5h 15m

Buffalo

Wed 2/5

6:00 am-10:47 am

1 stop5h 47m

$357

Kansas CityBuffalo

MCI - BUF

MCIBUF

Kansas City

Fri 2/21

6:00 am-1:35 pm

1 stop6h 35m

Buffalo

Sun 2/23

6:22 am-10:03 am

1 stop4h 41m

$367

Kansas CityBuffalo

MCI - BUF

MCIBUF

Kansas City

Sun 5/25

6:00 am-1:46 pm

2 stops6h 46m

Buffalo

Sun 6/1

7:00 am-10:29 am

1 stop4h 29m

$372

St. LouisBuffalo

STL - BUF

STLBUF

Lambert-St Louis

Fri 6/6

4:49 pm-10:15 pm

1 stop4h 26m

Buffalo

Sun 6/8

5:33 am-9:05 am

1 stop4h 32m

$397

St. LouisBuffalo

STL - BUF

STLBUF

Lambert-St Louis

Sun 7/13

5:35 am-12:40 pm

1 stop6h 05m

Buffalo

Mon 7/21

8:30 pm-11:40 pm

1 stop4h 10m

$407

Kansas CityBuffalo

MCI - BUF

MCIBUF

Kansas City

Sat 5/17

7:10 am-4:30 pm

2 stops8h 20m

Buffalo

Mon 5/19

6:25 am-11:25 am

2 stops6h 00m

$417

Kansas CityBuffalo

MCI - BUF

MCIBUF

Kansas City

Thu 2/13

6:21 am-3:24 pm

2 stops8h 03m

Buffalo

Sun 2/16

11:13 am-5:44 pm

1 stop7h 31m

$433

SpringfieldBuffalo

SGF - BUF

SGFBUF

Springfield-Branson

Thu 6/5

7:19 am-12:50 pm

1 stop4h 31m

Buffalo

Mon 6/9

8:00 am-11:20 am

1 stop4h 20m

$462

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/16

Showing 1-10 of 19 results
1
2

Best time to book a flight from Missouri to Buffalo

Have a flexible travel schedule? Discover the best time to fly to Buffalo from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Missouri to Buffalo

Get recent, data-driven insights about flights from Missouri to Buffalo including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Missouri to Buffalo?

Currently, January is the cheapest month in which you can book a flight from Missouri to Buffalo (average of $256). Flying from Missouri to Buffalo in December is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to BUF?

Find hourly flight availability from Missouri to Buffalo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 17, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Missouri to Buffalo as you normally would.

Rainfall in Buffalo by month

Plan your trip to Buffalo by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Buffalo ranges from 2.5 - 4.0 inches per month. November is typically the wettest month, when rainfall can reach 4.0 in. February is typically the driest time to visit Buffalo when rainfall is around 2.5 in.

Temperature in Buffalo by month

Plan your trip to Buffalo by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Buffalo, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 71.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 24.8 F).

Reviews of airlines servicing Buffalo

Get insights into the airlines that provide service to Buffalo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Buffalo. Reviews last updated January 17, 2025.
Read through reviews of airlines operating flights from Missouri to Buffalo, such as Delta, United Airlines and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
4,659 reviews

Boarding

8.2

Food

7.2

Overall

8.1

Comfort

8.1

Crew

8.7

Entertainment

7.7

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Southwest
8.1
Very good
4,659 reviews
Southwest
8.1
Very good
4,659 reviews

Boarding

8.2

Food

7.2

Overall

8.1

Comfort

8.1

Crew

8.7

Entertainment

7.7

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Delta
8.0
Very good
8,511 reviews
Southwest
8.1
Very good
4,659 reviews

Boarding

8.2

Food

7.2

Overall

8.1

Comfort

8.1

Crew

8.7

Entertainment

7.7

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

United Airlines
7.4
Good
8,965 reviews
Southwest
8.1
Very good
4,659 reviews

Boarding

8.2

Food

7.2

Overall

8.1

Comfort

8.1

Crew

8.7

Entertainment

7.7

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

American Airlines
7.2
Good
10,000 reviews
Southwest
8.1
Very good
4,659 reviews

Boarding

8.2

Food

7.2

Overall

8.1

Comfort

8.1

Crew

8.7

Entertainment

7.7

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Frontier
6.1
Okay
3,435 reviews
Southwest
8.1
Very good
4,659 reviews

Boarding

8.2

Food

7.2

Overall

8.1

Comfort

8.1

Crew

8.7

Entertainment

7.7

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Buffalo from Missouri?

    Most people fly into Buffalo (BUF) if they book a flight to Buffalo from Missouri. Buffalo is conveniently located just 8.3 mi from Buffalo’s city center.

  • What are the cheapest airlines to fly from Missouri to Buffalo one-way?

    One-way options have recently been found by users for as low as $110 on Frontier. Other airlines that offer cheap prices include American Airlines from $149 and United Airlines from $194 one-way.

  • What are the most popular routes from Missouri to Buffalo?

    While some choose either Kansas City - Buffalo or Springfield-Branson - Buffalo, Lambert-St Louis - Buffalo is the most popular route from Missouri to Buffalo.

  • Can I find deals for flights from Missouri to Buffalo that include hotel bookings?

    Yes. In addition to deals on Missouri to Buffalo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Buffalo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Buffalo.

  • Can I find deals for business class flights from Missouri to Buffalo?

    Yes. Cheapflights offers flight deals from Missouri to Buffalo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Buffalo?

    Currently, January is the cheapest month in which you can book a flight from Missouri to Buffalo (average of $256). Flying from Missouri to Buffalo in December is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Missouri?

Book flights to Missouri if you plan to visit one of these locations
West Seneca
Williamsville
Amherst
Batavia
Orchard Park
Cheektowaga

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Top 6 airlines flying from Missouri to Buffalo

Discover the top 6 airlines that operate flights from Missouri to Buffalo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$137Average$248FlexibilityNo cancel feeOn-time62%
JetBlueCheapest$197Average$348FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$253Average$445FlexibilityNo cancel feeOn-time71%
DeltaCheapest$256Average$399FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$278Average$436FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$306Average$464FlexibilityNo cancel feeOn-time63%
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