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$149+ Cheap flights from Mississippi to Buffalo (BUF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/24. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — BUF
Apr 29 — May 61
Tue 4/29
Tue 5/6
1 adult, Economy
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Cheap flight deals from Mississippi to Buffalo

Keep the following information in mind while searching for Mississippi to Buffalo flight deals. Data was last updated April 24, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$259
(Delta)

One-way from

$149
(American Airlines)
Provider with most accurate pricing for Jackson-Evers Intl-Buffalo flight deals.
Search Deals
Provider most trusted by Cheapflights users for Jackson-Evers Intl-Buffalo flights.
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From Mississippi to Buffalo
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One-way flight from Mississippi to Buffalo
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Find flight deals from Mississippi to Buffalo

Cheapest flights from Mississippi to Buffalo
Explore the most affordable flight options available from Mississippi to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 24, 2025.

This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/46:05 pmGPT - BUF
1 stop4h 50mDelta
Mon 6/912:10 pmBUF - GPT
1 stop6h 39mDelta
Deal found 4/22$259
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/46:21 pmGPT - BUF
1 stop4h 53mAmerican Airlines
Sat 6/72:34 pmBUF - GPT
2 stops10h 23mAmerican Airlines
Deal found 4/22$264
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/297:30 amMEM - BUF
1 stop4h 51mUnited Airlines
Thu 6/57:00 amBUF - MEM
1 stop5h 02mUnited Airlines
Deal found 4/22$300
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/243:47 pmMEM - BUF
1 stop5h 00mAmerican Airlines
Tue 5/277:11 pmBUF - MEM
1 stop5h 33mAmerican Airlines
Deal found 4/23$303
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/214:20 pmMEM - BUF
1 stop6h 35mDelta
Fri 5/236:35 pmBUF - MEM
1 stop5h 41mDelta
Deal found 4/23$314
This Southwest deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/242:00 pmMEM - BUF
2 stops8h 10mSouthwest
Tue 5/277:20 pmBUF - MEM
1 stop4h 20mSouthwest
Deal found 4/23$329
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/135:58 pmJAN - BUF
1 stop4h 48mDelta
Sun 6/157:35 pmBUF - JAN
1 stop4h 59mDelta
Deal found 4/23$362
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/85:05 amBTR - BUF
2 stops10h 50mUnited Airlines
Mon 5/1211:00 amBUF - BTR
2 stops11h 48mUnited Airlines
Deal found 4/23$379
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/196:32 pmBTR - BUF
1 stop5h 06mAmerican Airlines
Sun 6/295:44 pmBUF - BTR
1 stop5h 21mAmerican Airlines
Deal found 4/23$423
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/193:21 pmBTR - BUF
1 stop7h 25mDelta
Sun 6/225:10 pmBUF - BTR
1 stop6h 15mDelta
Deal found 4/23$449
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/268:00 amMOB - BUF
1 stop5h 05mUnited Airlines
Sun 4/276:00 amBUF - MOB
2 stops11h 08mUnited Airlines
Deal found 4/22$464
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/265:11 pmMOB - BUF
1 stop5h 46mDelta
Sun 4/276:45 pmBUF - MOB
1 stop5h 02mDelta
Deal found 4/22$474

Cheapflights Fare Finder

Customize your flight search to find flights from Mississippi to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2025.
Use the filters below to find and compare flights from Mississippi to Buffalo that are best for you.

Fly from

Mississippi

Fly to

Buffalo

Route

Depart

Return

Price

GulfportBuffalo

GPT - BUF

GPTBUF

Gulfport Biloxi Regional

Wed 6/4

6:05 pm-11:55 pm

1 stop4h 50m

Buffalo

Mon 6/9

12:10 pm-5:49 pm

1 stop6h 39m

$259

GulfportBuffalo

GPT - BUF

GPTBUF

Gulfport Biloxi Regional

Wed 6/4

6:21 pm-12:14 am

1 stop4h 53m

Buffalo

Sat 6/7

2:34 pm-11:57 pm

2 stops10h 23m

$264

MemphisBuffalo

MEM - BUF

MEMBUF

Memphis

Thu 5/29

7:30 am-1:21 pm

1 stop4h 51m

Buffalo

Thu 6/5

7:00 am-11:02 am

1 stop5h 02m

$300

MemphisBuffalo

MEM - BUF

MEMBUF

Memphis

Sat 5/24

3:47 pm-9:47 pm

1 stop5h 00m

Buffalo

Tue 5/27

7:11 pm-11:44 pm

1 stop5h 33m

$303

MemphisBuffalo

MEM - BUF

MEMBUF

Memphis

Wed 5/21

4:20 pm-11:55 pm

1 stop6h 35m

Buffalo

Fri 5/23

6:35 pm-11:16 pm

1 stop5h 41m

$314

MemphisBuffalo

MEM - BUF

MEMBUF

Memphis

Sat 5/24

2:00 pm-11:10 pm

2 stops8h 10m

Buffalo

Tue 5/27

7:20 pm-10:40 pm

1 stop4h 20m

$329

JacksonBuffalo

JAN - BUF

JANBUF

Jackson-Evers Intl

Fri 6/13

5:58 pm-11:46 pm

1 stop4h 48m

Buffalo

Sun 6/15

7:35 pm-11:34 pm

1 stop4h 59m

$362

Baton RougeBuffalo

BTR - BUF

BTRBUF

Baton Rouge Ryan

Thu 5/8

5:05 am-4:55 pm

2 stops10h 50m

Buffalo

Mon 5/12

11:00 am-9:48 pm

2 stops11h 48m

$379

Baton RougeBuffalo

BTR - BUF

BTRBUF

Baton Rouge Ryan

Thu 6/19

6:32 pm-12:38 am

1 stop5h 06m

Buffalo

Sun 6/29

5:44 pm-10:05 pm

1 stop5h 21m

$423

Baton RougeBuffalo

BTR - BUF

BTRBUF

Baton Rouge Ryan

Thu 6/19

3:21 pm-11:46 pm

1 stop7h 25m

Buffalo

Sun 6/22

5:10 pm-10:25 pm

1 stop6h 15m

$449

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/23

Showing 1-10 of 25 results
1
2
3

Best time to book a flight from Mississippi to Buffalo

Have a flexible travel schedule? Discover the best time to fly to Buffalo from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to Buffalo

Rainfall in Buffalo by month

Plan your trip to Buffalo by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Buffalo ranges from 2.5 - 4.0 inches per month. November is typically the wettest month, when rainfall can reach 4.0 in. February is typically the driest time to visit Buffalo when rainfall is around 2.5 in.

Temperature in Buffalo by month

Plan your trip to Buffalo by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Buffalo, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 71.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 24.8 F).

Reviews of airlines servicing Buffalo

Get insights into the airlines that provide service to Buffalo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Buffalo. Reviews last updated April 24, 2025.
Get a feel of what it's like to fly with Southwest, Delta and United Airlines from Mississippi to Buffalo by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,286 reviews

Entertainment

7.6

Food

7.1

Boarding

8.2

Comfort

8.0

Crew

8.6

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
Southwest
8.0
Very good
4,286 reviews
Southwest
8.0
Very good
4,286 reviews

Entertainment

7.6

Food

7.1

Boarding

8.2

Comfort

8.0

Crew

8.6

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
Delta
8.0
Very good
7,920 reviews
Southwest
8.0
Very good
4,286 reviews

Entertainment

7.6

Food

7.1

Boarding

8.2

Comfort

8.0

Crew

8.6

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
United Airlines
7.4
Good
8,685 reviews
Southwest
8.0
Very good
4,286 reviews

Entertainment

7.6

Food

7.1

Boarding

8.2

Comfort

8.0

Crew

8.6

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,286 reviews

Entertainment

7.6

Food

7.1

Boarding

8.2

Comfort

8.0

Crew

8.6

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!

Related info for your journey

Find useful and relevant information for your journey from Mississippi to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Buffalo from Mississippi?

    If you book a flight to Buffalo from Mississippi, you will be flying to Buffalo, which is the city’s only airport. Buffalo (BUF) is located 8.3 mi from the center of Buffalo.

  • What are the cheapest airlines to fly from Mississippi to Buffalo one-way?

    One-way options have recently been found by users for as low as $149 on American Airlines. Other airlines that offer cheap prices include Southwest from $154 and Delta from $189 one-way.

  • What are the most popular routes from Mississippi to Buffalo?

    The most popular route from Mississippi to Buffalo is Memphis - Buffalo. You may also consider Baton Rouge Ryan - Buffalo or Jackson-Evers Intl - Buffalo.

  • Can I find deals for flights from Mississippi to Buffalo that include hotel bookings?

    Yes. In addition to deals on Mississippi to Buffalo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to Buffalo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to Buffalo.

  • Can I find deals for business class flights from Mississippi to Buffalo?

    Yes. Cheapflights offers flight deals from Mississippi to Buffalo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mississippi to Buffalo?

    Currently, January is the cheapest month in which you can book a flight from Mississippi to Buffalo (average of $256). Flying from Mississippi to Buffalo in December is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Mississippi?

Book flights to Mississippi if you plan to visit one of these locations
West Seneca
Williamsville
Amherst
Batavia
Orchard Park
Cheektowaga

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Top 2 airlines flying from Mississippi to Buffalo

Discover the top 2 airlines that operate flights from Mississippi to Buffalo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$238Average$439FlexibilityNo cancel feeOn-time71%
DeltaCheapest$309Average$537FlexibilityNo cancel feeOn-timeN/A

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