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$125+ Cheap flights from Mesa, AZ to Buffalo (BUF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/3. Fares are subject to change and may not be available on all flights or dates of travel.
PHX — BUF
Apr 5 — Apr 121
Sa 4/5
Sa 4/12
1 adult, Economy
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Cheapflights Tip: The best prices from Mesa to Buffalo are usually found in August or September, booked 72 days in advance, depart on a Monday or Thursday and return on a Wednesday

Cheap flight deals from Mesa to Buffalo

Keep the following information in mind while searching for Mesa to Buffalo flight deals. Data was last updated März 31, 2025.

Round-trip from

$240
(CheapOair)

One-way from

$125
(Frontier)

Popular in

February

Cheapest in

August

Average price

$330
From Mesa to Buffalo
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One-way flight from Mesa to Buffalo
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Highest demand for flights based on searches. 11% potential increase in price ($45 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($12 potential savings vs. average RT price).
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Average for round-trip flights in March 2025
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Find flight deals from Mesa to Buffalo

Cheapest flights from Mesa to Buffalo
Explore the most affordable flight options available from Mesa to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on März 31, 2025.

This CheapOair deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sa 4/263:07 pmPHX - BUF
1 stop14h 55mFrontier
Mo 4/287:00 pmBUF - PHX
1 stop22h 02mFrontier
Deal found 3/30$240
This Southwest deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Di 8/1910:00 amPHX - BUF
1 stop7h 45mSouthwest
Di 9/96:45 pmBUF - PHX
1 stop6h 15mSouthwest
Deal found 3/29$249
This Delta deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 7/236:05 amPHX - BUF
1 stop9h 30mDelta
Mo 7/287:20 pmBUF - PHX
1 stop6h 34mDelta
Deal found 3/30$257
This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 8/1312:52 amPHX - BUF
1 stop8h 53mAmerican Airlines
Mo 8/188:05 pmBUF - PHX
1 stop6h 36mAmerican Airlines
Deal found 3/30$274
This United Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sa 6/76:50 pmPHX - BUF
2 stops12h 06mUnited Airlines
Fr 6/135:51 pmBUF - PHX
1 stop7h 04mUnited Airlines
Deal found 3/31$344
This JetBlue deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fr 7/119:50 pmPHX - BUF
1 stop10h 52mJetBlue
So 7/1312:29 pmBUF - PHX
1 stop11h 05mJetBlue
Deal found 3/31$422
This Sun Country Air deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Sun Country Air is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 7/236:15 pmPHX - BUF
1 stop13h 29mSun Country Air
So 7/2711:40 amBUF - PHX
1 stop8h 34mSun Country Air
Deal found 3/30$425
This Alaska Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fr 10/246:45 pmPHX - BUF
2 stops12h 54mAlaska Airlines
So 10/265:17 amBUF - PHX
2 stops16h 54mAlaska Airlines
Deal found 3/30$586

Cheapflights Fare Finder

Customize your flight search to find flights from Mesa to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated März 31, 2025.
Use the filters below to find and compare flights from Mesa to Buffalo that are best for you.

Fly from

Mesa

Fly to

Buffalo

Route

Depart

Return

Price

PhoenixBuffalo

PHX - BUF

PHXBUF

Phoenix Sky Harbor Intl

Sa 4/26

3:07 pm-9:02 am

1 stop14h 55m

Buffalo

Mo 4/28

7:00 pm-2:02 pm

1 stop22h 02m

$240

PhoenixBuffalo

PHX - BUF

PHXBUF

Phoenix Sky Harbor Intl

Di 8/19

10:00 am-8:45 pm

1 stop7h 45m

Buffalo

Di 9/9

6:45 pm-10:00 pm

1 stop6h 15m

$249

PhoenixBuffalo

PHX - BUF

PHXBUF

Phoenix Sky Harbor Intl

Mi 7/23

6:05 am-6:35 pm

1 stop9h 30m

Buffalo

Mo 7/28

7:20 pm-10:54 pm

1 stop6h 34m

$257

PhoenixBuffalo

PHX - BUF

PHXBUF

Phoenix Sky Harbor Intl

Mi 8/13

12:52 am-12:45 pm

1 stop8h 53m

Buffalo

Mo 8/18

8:05 pm-11:41 pm

1 stop6h 36m

$274

PhoenixBuffalo

PHX - BUF

PHXBUF

Phoenix Sky Harbor Intl

Sa 6/7

6:50 pm-9:56 am

2 stops12h 06m

Buffalo

Fr 6/13

5:51 pm-9:55 pm

1 stop7h 04m

$344

PhoenixBuffalo

PHX - BUF

PHXBUF

Phoenix Sky Harbor Intl

Fr 7/11

9:50 pm-11:42 am

1 stop10h 52m

Buffalo

So 7/13

12:29 pm-8:34 pm

1 stop11h 05m

$422

PhoenixBuffalo

PHX - BUF

PHXBUF

Phoenix Sky Harbor Intl

Mi 7/23

6:15 pm-10:44 am

1 stop13h 29m

Buffalo

So 7/27

11:40 am-5:14 pm

1 stop8h 34m

$425

PhoenixBuffalo

PHX - BUF

PHXBUF

Phoenix Sky Harbor Intl

Di 8/19

2:16 pm-9:34 am

3 stops16h 18m

Buffalo

Di 9/9

1:42 pm-11:55 pm

2 stops13h 13m

$613

PhoenixBuffalo

PHX - BUF

PHXBUF

Phoenix Sky Harbor Intl

Sa 5/3

3:11 pm-9:01 am

1 stop14h 50m

$125

PhoenixBuffalo

PHX - BUF

PHXBUF

Phoenix Sky Harbor Intl

Sa 4/26

9:51 am-11:44 pm

2 stops10h 53m

$130

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/30

Showing 1-10 of 16 results
1
2

Best time to book a flight from Mesa to Buffalo

Have a flexible travel schedule? Discover the best time to fly to Buffalo from Mesa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mesa to Buffalo

How far ahead should I book a flight from Mesa to Buffalo?

Use this chart to determine the optimal time to book a round-trip flight from Mesa to Buffalo. Price data was last updated on March 28, 2025.

Booking 72 days in advance of your planned departure date is, on average, the best time to get cheap flights from Mesa to Buffalo. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Mesa to Buffalo?

Currently, January is the cheapest month in which you can book a flight from Mesa to Buffalo (average of $256). Flying from Mesa to Buffalo in December is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MS9 to BUF?

Find hourly flight availability from Mesa to Buffalo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated März 31, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Mesa to Buffalo as you normally would.

What is the cheapest day to fly from Mesa to Buffalo?

Use this chart to determine the cheapest time to fly round-trip from Mesa to Buffalo. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Mesa to Buffalo flight should consider departing on Sunday evenings when fares are most often at their lowest. Saturday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Rainfall in Buffalo by month

Plan your trip to Buffalo by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Buffalo ranges from 2.5 - 4.0 inches per month. November is typically the wettest month, when rainfall can reach 4.0 in. February is typically the driest time to visit Buffalo when rainfall is around 2.5 in.

Temperature in Buffalo by month

Plan your trip to Buffalo by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Buffalo, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 71.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 24.8 F).

Reviews of airlines servicing Buffalo

Get insights into the airlines that provide service to Buffalo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Buffalo. Reviews last updated März 31, 2025.
Peruse reviews from past customers who have flown with Alaska Airlines, Southwest and Delta from Mesa to Buffalo to help guide your decision. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
9,818 reviews

Entertainment

7.1

Boarding

8.2

Crew

8.5

Comfort

7.9

Overall

8.0

Food

7.1

Reviews

1 / 20
10.0
Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them
Alaska Airlines
8.0
Very good
9,818 reviews
Alaska Airlines
8.0
Very good
9,818 reviews

Entertainment

7.1

Boarding

8.2

Crew

8.5

Comfort

7.9

Overall

8.0

Food

7.1

Reviews

1 / 20
10.0
Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them
Southwest
8.0
Very good
4,276 reviews
Alaska Airlines
8.0
Very good
9,818 reviews

Entertainment

7.1

Boarding

8.2

Crew

8.5

Comfort

7.9

Overall

8.0

Food

7.1

Reviews

1 / 20
10.0
Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them
Delta
8.0
Very good
7,899 reviews
Alaska Airlines
8.0
Very good
9,818 reviews

Entertainment

7.1

Boarding

8.2

Crew

8.5

Comfort

7.9

Overall

8.0

Food

7.1

Reviews

1 / 20
10.0
Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them
United Airlines
7.4
Good
8,614 reviews
Alaska Airlines
8.0
Very good
9,818 reviews

Entertainment

7.1

Boarding

8.2

Crew

8.5

Comfort

7.9

Overall

8.0

Food

7.1

Reviews

1 / 20
10.0
Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them
JetBlue
7.3
Good
2,924 reviews
Alaska Airlines
8.0
Very good
9,818 reviews

Entertainment

7.1

Boarding

8.2

Crew

8.5

Comfort

7.9

Overall

8.0

Food

7.1

Reviews

1 / 20
10.0
Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them

Related info for your journey

Find useful and relevant information for your journey from Mesa to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Buffalo from Mesa?

    If you book a flight to Buffalo from Mesa, you will be flying to Buffalo, which is the city’s only airport. Buffalo (BUF) is located 8.3 mi from the center of Buffalo. There are 0 flights from Mesa to Buffalo per day from 6 different airlines.

  • What are the cheapest airlines to fly from Mesa to Buffalo one-way?

    One-way options have recently been found by users for as low as $125 on Frontier. Other airlines that offer cheap prices include United Airlines from $130 and JetBlue from $135 one-way.

  • What are the cheapest flights from Mesa to Buffalo?

    On average you can expect to pay $431 for a flight from Mesa to Buffalo. The cheapest flight overall is $256 while the most popular route, (Phoenix Sky Harbor Intl - Buffalo) is currently priced at $249.

  • Can I find deals for flights from Mesa to Buffalo that include hotel bookings?

    Yes. In addition to deals on Mesa to Buffalo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mesa to Buffalo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mesa to Buffalo.

  • Can I find deals for business class flights from Mesa to Buffalo?

    Yes. Cheapflights offers flight deals from Mesa to Buffalo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mesa to Buffalo?

    Currently, January is the cheapest month in which you can book a flight from Mesa to Buffalo (average of $256). Flying from Mesa to Buffalo in December is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Mesa?

Book flights to Mesa if you plan to visit one of these locations
West Seneca
Williamsville
Amherst
Batavia
Orchard Park
Cheektowaga

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Top 6 airlines flying from Mesa to Buffalo

Discover the top 6 airlines that operate flights from Mesa to Buffalo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated März 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
JetBlueCheapest$124Average$338FlexibilityNo cancel feeOn-time62%
FrontierCheapest$145Average$251FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$169Average$320FlexibilityNo cancel feeOn-time71%
DeltaCheapest$235Average$320FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$245Average$355FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$313Average$522FlexibilityNo cancel feeOn-time63%
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