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$645+ Cheap flights from Knoxville (TYS) to Brussels

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/26. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — BRU
Feb 27 — Mar 61
Thu 2/27
Thu 3/6
1 adult, Economy
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Cheap flight deals from Knoxville to Brussels

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Brussels (BR1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 22, 2025.

Round-trip from

$645
(United)
From Knoxville McGhee Tyson to Brussels
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Cheapest flights from Knoxville to Brussels
Explore the most affordable flight options available from Knoxville to Brussels. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 22, 2025.

This United deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/267:00 amTYS - BRU
3 stops19h 55mUnited Airlines
Tue 4/812:00 pmBRU - TYS
2 stops28h 15mUnited Airlines
Deal found 2/21$645
This FlightHub deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/24:00 pmTYS - BRU
2 stops17h 20mScandinavian Airlines
Sun 11/238:30 pmBRU - TYS
2 stops33h 17mScandinavian Airlines
Deal found 2/21$755
This Mytrip deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/36:20 amTYS - BRU
3 stops30h 45mMultiple Airlines
Thu 4/1010:20 amBRU - TYS
3 stops31h 40mMultiple Airlines
Deal found 2/21$1,051
This Air Canada deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/269:55 amTYS - BRU
3 stops17h 00mAir Canada
Tue 4/87:00 amBRU - TYS
3 stops18h 36mAir Canada
Deal found 2/21$1,199

Find flights from Knoxville to Brussels within your budget

Customize your flight search to find flights from Knoxville to Brussels that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 22, 2025.

Fly from

Knoxville

Fly to

Brussels

Route

Depart

Return

Price

KnoxvilleBrussels

TYS - BRU

TYSBRU

Knoxville McGhee Tyson

Wed 3/26

9:55 am-7:55 am

2 stops17h 00m

Brussels Bruxelles-National

Tue 4/8

12:00 pm-10:22 pm

2 stops16h 22m

$645

KnoxvilleBrussels

TYS - BRU

TYSBRU

Knoxville McGhee Tyson

Thu 4/3

6:20 am-7:05 pm

3 stops30h 45m

Brussels Bruxelles-National

Thu 4/10

10:20 am-12:00 pm

3 stops31h 40m

$1,051

KnoxvilleBrussels

TYS - BRU

TYSBRU

Knoxville McGhee Tyson

Wed 3/26

9:55 am-7:55 am

3 stops17h 00m

Brussels Bruxelles-National

Tue 4/8

7:00 am-7:36 pm

3 stops18h 36m

$1,199

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/21

Best time to book a flight from Knoxville to Brussels

Have a flexible travel schedule? Discover the best time to fly to Brussels from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Knoxville to Brussels

Get recent, data-driven insights about flights from Knoxville to Brussels including ideal travel times, pricing trends, and more.

What is the cheapest time of day to fly from TYS to BRU?

Find hourly flight availability from Knoxville to Brussels. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 22, 2025.

A simple way to save on the total cost of your ticket is to fly from Knoxville to Brussels in the afternoon. If you’re flexible enough to do this you can expect to save up to 15% on your trip compared to booking a flight at noon.

Rainfall in Brussels by month

Plan your trip to Brussels by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Brussels ranges from 1.6 - 3.1 inches per month. January is typically the wettest month, when rainfall can reach 3.1 in. August is typically the driest time to visit Brussels when rainfall is around 1.6 in.

Temperature in Brussels by month

Plan your trip to Brussels by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Brussels, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 62.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 37.4 F).

Reviews of airlines servicing Brussels

Get insights into the airlines that provide service to Brussels. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Brussels. Reviews last updated February 22, 2025.
United Airlines
7.4
Good
8,754 reviews

Crew

8.1

Boarding

7.7

Comfort

7.3

Overall

7.4

Food

6.7

Entertainment

7.1

Reviews

1 / 20

2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!

United Airlines
7.4
Good
8,754 reviews
United Airlines
7.4
Good
8,754 reviews

Crew

8.1

Boarding

7.7

Comfort

7.3

Overall

7.4

Food

6.7

Entertainment

7.1

Reviews

1 / 20

2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!

Air Canada
7.0
Good
8,757 reviews
United Airlines
7.4
Good
8,754 reviews

Crew

8.1

Boarding

7.7

Comfort

7.3

Overall

7.4

Food

6.7

Entertainment

7.1

Reviews

1 / 20

2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Brussels. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Brussels?

    Most people fly from Knoxville McGhee Tyson (TYS) if they book a flight from Knoxville to Brussels. On average, McGhee Tyson has 0 outbound flights to Brussels per day from 1 airline. Knoxville McGhee Tyson is conveniently located just 11.3 mi from Knoxville’s city center.

  • What are the cheapest airlines flying from Knoxville to Brussels round-trip?

    Flying on United Airlines is currently your cheapest option to Brussels, with prices starting at $645. Another option worth looking into is Air Canada, starting at $1,199 round trip.

  • Can I find deals for flights from Knoxville to Brussels that include hotel bookings?

    Yes. In addition to deals on Knoxville to Brussels flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Brussels?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Brussels.

  • Can I find deals for business class flights from Knoxville to Brussels?

    Yes. Cheapflights offers flight deals from Knoxville to Brussels by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Brussels?

    Currently, November is the cheapest month in which you can book a flight from Knoxville to Brussels (average of $614). Flying from Knoxville to Brussels in June is currently the most expensive (average of $1,146). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Knoxville to Brussels

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Knoxville to Brussels

Discover the top airline that operate flights from Knoxville to Brussels. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 22, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$814Average$1,252FlexibilityNo cancel feeOn-time69%
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