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$588+ Cheap flights from Des Moines (DSM) to Brussels

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/14. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — BRU
Apr 5 — Apr 121
Sat 4/5
Sat 4/12
1 adult, Economy
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Cheap flight deals from Des Moines to Brussels

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Brussels (BR1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 31, 2025.

Round-trip from

$730
(Gotogate)

One-way from

$588
(EaseMyTrip)
From Des Moines to Brussels
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One-way flight from Des Moines to Brussels
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Find flight deals from Des Moines to Brussels

Cheapest flights from Des Moines to Brussels
Explore the most affordable flight options available from Des Moines to Brussels. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 31, 2025.

This Gotogate deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/1411:26 amDSM - BRU
2 stops13h 39mAir Canada
Wed 5/2110:00 amBRU - DSM
2 stops42h 22mAir Canada
Deal found 3/30$730
This United Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/148:07 amDSM - BRU
1 stop17h 53mUnited Airlines
Wed 5/2110:00 amBRU - DSM
2 stops42h 22mUnited Airlines
Deal found 3/30$769
This Flighttix deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/1411:26 amDSM - BRU
1 stop14h 34mLufthansa
Wed 5/2110:15 amBRU - DSM
1 stop18h 37mLufthansa
Deal found 3/30$779
This Flighttix deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/1411:26 amDSM - BRU
1 stop14h 34mMultiple Airlines
Wed 5/219:40 amBRU - DSM
2 stops20h 59mMultiple Airlines
Deal found 3/30$783
This CheapTickets.ch deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapTickets.ch is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/1411:26 amDSM - BRU
2 stops13h 39mSWISS
Wed 5/2110:15 amBRU - DSM
1 stop14h 35mSWISS
Deal found 3/30$791
This oojo deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2211:53 amDSM - BRU
2 stops19h 17mBritish Airways
Mon 5/269:15 pmBRU - DSM
2 stops27h 28mBritish Airways
Deal found 3/30$1,039

Cheapflights Fare Finder

Customize your flight search to find flights from Des Moines to Brussels that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 31, 2025.
Use the filters below to find and compare flights from Des Moines to Brussels that are best for you.

Fly from

Des Moines

Fly to

Brussels

Route

Depart

Return

Price

Des MoinesBrussels

DSM - BRU

DSMBRU

Des Moines

Wed 5/14

11:26 am-8:05 am

2 stops13h 39m

Brussels Bruxelles-National

Wed 5/21

10:00 am-9:22 pm

2 stops42h 22m

$730

Des MoinesBrussels

DSM - BRU

DSMBRU

Des Moines

Wed 5/14

11:26 am-8:05 am

2 stops13h 39m

Brussels Bruxelles-National

Wed 5/21

10:00 am-9:22 pm

2 stops42h 22m

$769

Des MoinesBrussels

DSM - BRU

DSMBRU

Des Moines

Wed 5/14

11:26 am-9:00 am

1 stop14h 34m

Brussels Bruxelles-National

Wed 5/21

10:15 am-9:52 pm

1 stop18h 37m

$779

Des MoinesBrussels

DSM - BRU

DSMBRU

Des Moines

Wed 5/14

11:26 am-9:00 am

1 stop14h 34m

Brussels Bruxelles-National

Wed 5/21

9:40 am-11:39 pm

2 stops20h 59m

$783

Des MoinesBrussels

DSM - BRU

DSMBRU

Des Moines

Wed 5/14

11:26 am-8:05 am

2 stops13h 39m

Brussels Bruxelles-National

Wed 5/21

10:15 am-5:50 pm

1 stop14h 35m

$791

Des MoinesBrussels

DSM - BRU

DSMBRU

Des Moines

Thu 5/22

11:53 am-2:10 pm

2 stops19h 17m

Brussels Bruxelles-National

Mon 5/26

9:15 pm-5:43 pm

2 stops27h 28m

$1,039

Des MoinesBrussels

DSM - BRU

DSMBRU

Des Moines

Wed 5/14

11:26 am-8:05 am

2 stops13h 39m

$588

Des MoinesBrussels

DSM - BRU

DSMBRU

Des Moines

Wed 5/14

8:07 am-9:00 am

1 stop17h 53m

$598

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/30

Best time to book a flight from Des Moines to Brussels

Have a flexible travel schedule? Discover the best time to fly to Brussels from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Brussels

Rainfall in Brussels by month

Plan your trip to Brussels by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Brussels ranges from 1.6 - 3.1 inches per month. January is typically the wettest month, when rainfall can reach 3.1 in. August is typically the driest time to visit Brussels when rainfall is around 1.6 in.

Temperature in Brussels by month

Plan your trip to Brussels by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Brussels, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 62.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 37.4 F).

Reviews of airlines servicing Brussels

Get insights into the airlines that provide service to Brussels. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Brussels. Reviews last updated March 31, 2025.
SWISS
7.5
Good
1,570 reviews

Boarding

7.6

Crew

8.2

Comfort

7.3

Food

7.0

Entertainment

6.7

Overall

7.5

Reviews

1 / 20
6.0
Good

Yvette,Nov 2024

BOS - ZRH

Food was not very good and the options were poor. The seat wasn't very comfortable. I would not choose to fly on this airline again. Their website was also difficult to navigate.
SWISS
7.5
Good
1,570 reviews
SWISS
7.5
Good
1,570 reviews

Boarding

7.6

Crew

8.2

Comfort

7.3

Food

7.0

Entertainment

6.7

Overall

7.5

Reviews

1 / 20
6.0
Good

Yvette,Nov 2024

BOS - ZRH

Food was not very good and the options were poor. The seat wasn't very comfortable. I would not choose to fly on this airline again. Their website was also difficult to navigate.
United Airlines
7.4
Good
8,614 reviews
SWISS
7.5
Good
1,570 reviews

Boarding

7.6

Crew

8.2

Comfort

7.3

Food

7.0

Entertainment

6.7

Overall

7.5

Reviews

1 / 20
6.0
Good

Yvette,Nov 2024

BOS - ZRH

Food was not very good and the options were poor. The seat wasn't very comfortable. I would not choose to fly on this airline again. Their website was also difficult to navigate.
Air Canada
7.0
Good
9,004 reviews
SWISS
7.5
Good
1,570 reviews

Boarding

7.6

Crew

8.2

Comfort

7.3

Food

7.0

Entertainment

6.7

Overall

7.5

Reviews

1 / 20
6.0
Good

Yvette,Nov 2024

BOS - ZRH

Food was not very good and the options were poor. The seat wasn't very comfortable. I would not choose to fly on this airline again. Their website was also difficult to navigate.
Lufthansa
6.7
Okay
6,960 reviews
SWISS
7.5
Good
1,570 reviews

Boarding

7.6

Crew

8.2

Comfort

7.3

Food

7.0

Entertainment

6.7

Overall

7.5

Reviews

1 / 20
6.0
Good

Yvette,Nov 2024

BOS - ZRH

Food was not very good and the options were poor. The seat wasn't very comfortable. I would not choose to fly on this airline again. Their website was also difficult to navigate.
British Airways
6.6
Okay
6,713 reviews
SWISS
7.5
Good
1,570 reviews

Boarding

7.6

Crew

8.2

Comfort

7.3

Food

7.0

Entertainment

6.7

Overall

7.5

Reviews

1 / 20
6.0
Good

Yvette,Nov 2024

BOS - ZRH

Food was not very good and the options were poor. The seat wasn't very comfortable. I would not choose to fly on this airline again. Their website was also difficult to navigate.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Brussels. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Brussels?

    Des Moines (DSM), located 3.6 mi from the city center, is the airport you fly out of when you book flights from Des Moines to Brussels. 1 airline have flights from Des Moines to Brussels on a regular basis. Booking flights from Des Moines to Brussels should not be difficult; the airport handles an average of 0 outbound flights to Brussels per day.

  • What are the cheapest airlines flying from Des Moines to Brussels round-trip?

    According to our current data, Air Canada ($730), United Airlines ($769), and Lufthansa ($779) offers the cheapest pricing from Des Moines to Brussels.

  • Can I find deals for flights from Des Moines to Brussels that include hotel bookings?

    Yes. In addition to deals on Des Moines to Brussels flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Brussels?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Brussels.

  • Can I find deals for business class flights from Des Moines to Brussels?

    Yes. Cheapflights offers flight deals from Des Moines to Brussels by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Brussels?

    Currently, November is the cheapest month in which you can book a flight from Des Moines to Brussels (average of $614). Flying from Des Moines to Brussels in June is currently the most expensive (average of $1,146). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Des Moines to Brussels

See prices for flight routes from nearby airports that may be better suited for you.
Des Moines to Bruxelles-National flights
Omaha to Bruxelles-National flights

Top airline flying from Des Moines to Brussels

Discover the top airline that operate flights from Des Moines to Brussels. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$794Average$1,333FlexibilityNo cancel feeOn-time69%
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