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$512+ Cheap flights from Des Moines (DSM) to Brussels

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/13. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — BRU
Apr 30 — May 71
Wed 4/30
Wed 5/7
1 adult, Economy
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Cheap flight deals from Des Moines to Brussels

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Brussels (BR1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 25, 2025.

Round-trip from

$821
(Gotogate)

One-way from

$512
(StudentUniverse)
From Des Moines to Brussels
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One-way flight from Des Moines to Brussels
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Find flight deals from Des Moines to Brussels

Cheapest flights from Des Moines to Brussels
Explore the most affordable flight options available from Des Moines to Brussels. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 25, 2025.

This Gotogate deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/116:45 pmDSM - BRU
2 stops30h 20mAir Canada
Sun 5/1810:00 amBRU - DSM
2 stops31h 40mAir Canada
Deal found 4/25$821
This United Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/118:07 amDSM - BRU
1 stop17h 53mUnited Airlines
Sun 5/1810:15 amBRU - DSM
2 stops19h 30mUnited Airlines
Deal found 4/25$858
This Air Canada deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/118:07 amDSM - BRU
2 stops16h 43mMultiple Airlines
Sun 5/189:50 amBRU - DSM
3 stops19h 02mMultiple Airlines
Deal found 4/25$997
This Booking.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/95:58 pmDSM - BRU
2 stops32h 57mBritish Airways
Mon 6/169:15 pmBRU - DSM
2 stops27h 13mBritish Airways
Deal found 4/24$1,153
This Delta deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/910:59 amDSM - BRU
2 stops14h 41mDelta
Mon 6/163:05 pmBRU - DSM
2 stops29h 58mDelta
Deal found 4/25$1,163
This Ticket deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ticket is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/810:59 amDSM - BRU
2 stops14h 41mAir France
Sun 6/1510:45 amBRU - DSM
1 stop19h 18mAir France
Deal found 4/25$1,169

Cheapflights Fare Finder

Customize your flight search to find flights from Des Moines to Brussels that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 25, 2025.
Use the filters below to find and compare flights from Des Moines to Brussels that are best for you.

Fly from

Des Moines

Fly to

Brussels

Route

Depart

Return

Price

Des MoinesBrussels

DSM - BRU

DSMBRU

Des Moines

Sun 5/11

6:45 pm-8:05 am

2 stops30h 20m

Brussels Bruxelles-National

Sun 5/18

10:00 am-10:40 am

2 stops31h 40m

$821

Des MoinesBrussels

DSM - BRU

DSMBRU

Des Moines

Sun 5/11

8:07 am-9:00 am

1 stop17h 53m

Brussels Bruxelles-National

Sun 5/18

10:15 am-10:45 pm

2 stops19h 30m

$858

Des MoinesBrussels

DSM - BRU

DSMBRU

Des Moines

Sun 5/11

8:07 am-7:50 am

2 stops16h 43m

Brussels Bruxelles-National

Sun 5/18

9:50 am-9:52 pm

3 stops19h 02m

$997

Des MoinesBrussels

DSM - BRU

DSMBRU

Des Moines

Mon 6/9

5:58 pm-9:55 am

2 stops32h 57m

Brussels Bruxelles-National

Mon 6/16

9:15 pm-5:28 pm

2 stops27h 13m

$1,153

Des MoinesBrussels

DSM - BRU

DSMBRU

Des Moines

Mon 6/9

10:59 am-8:40 am

2 stops14h 41m

Brussels Bruxelles-National

Mon 6/16

3:05 pm-2:03 pm

2 stops29h 58m

$1,163

Des MoinesBrussels

DSM - BRU

DSMBRU

Des Moines

Sun 6/8

10:59 am-8:40 am

2 stops14h 41m

Brussels Bruxelles-National

Sun 6/15

10:45 am-11:03 pm

1 stop19h 18m

$1,169

Des MoinesBrussels

DSM - BRU

DSMBRU

Des Moines

Tue 5/13

5:32 am-9:40 am

2 stops21h 08m

$512

Des MoinesBrussels

DSM - BRU

DSMBRU

Des Moines

Tue 5/13

11:26 am-9:00 am

1 stop14h 34m

$573

Des MoinesBrussels

DSM - BRU

DSMBRU

Des Moines

Tue 5/13

1:07 pm-9:00 pm

3 stops24h 53m

$592

Des MoinesBrussels

DSM - BRU

DSMBRU

Des Moines

Mon 6/9

8:00 am-8:00 am

2 stops17h 00m

$817

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/25

Showing 1-10 of 11 results
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Best time to book a flight from Des Moines to Brussels

Have a flexible travel schedule? Discover the best time to fly to Brussels from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Brussels

Rainfall in Brussels by month

Plan your trip to Brussels by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Brussels ranges from 1.6 - 3.1 inches per month. January is typically the wettest month, when rainfall can reach 3.1 in. August is typically the driest time to visit Brussels when rainfall is around 1.6 in.

Temperature in Brussels by month

Plan your trip to Brussels by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Brussels, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 62.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 37.4 F).

Reviews of airlines servicing Brussels

Get insights into the airlines that provide service to Brussels. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Brussels. Reviews last updated April 25, 2025.
Delta
8.0
Very good
7,920 reviews

Boarding

8.2

Entertainment

7.9

Food

7.3

Comfort

7.9

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,920 reviews
Delta
8.0
Very good
7,920 reviews

Boarding

8.2

Entertainment

7.9

Food

7.3

Comfort

7.9

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Air France
7.4
Good
1,444 reviews
Delta
8.0
Very good
7,920 reviews

Boarding

8.2

Entertainment

7.9

Food

7.3

Comfort

7.9

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
United Airlines
7.4
Good
8,685 reviews
Delta
8.0
Very good
7,920 reviews

Boarding

8.2

Entertainment

7.9

Food

7.3

Comfort

7.9

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Air Canada
7.0
Good
9,207 reviews
Delta
8.0
Very good
7,920 reviews

Boarding

8.2

Entertainment

7.9

Food

7.3

Comfort

7.9

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Aer Lingus
7.0
Good
1,070 reviews
Delta
8.0
Very good
7,920 reviews

Boarding

8.2

Entertainment

7.9

Food

7.3

Comfort

7.9

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Brussels. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Brussels?

    Des Moines (DSM), located 3.6 mi from the city center, is the airport you fly out of when you book flights from Des Moines to Brussels. 1 airline have flights from Des Moines to Brussels on a regular basis. Booking flights from Des Moines to Brussels should not be difficult; the airport handles an average of 0 outbound flights to Brussels per day.

  • What are the cheapest airlines flying from Des Moines to Brussels round-trip?

    According to our current data, Air Canada ($821), United Airlines ($858), and British Airways ($1,153) offers the cheapest pricing from Des Moines to Brussels.

  • What are the cheapest airlines to fly from Des Moines to Brussels one-way?

    The cheapest airlines for a one-way flight from Des Moines to Brussels are Aer Lingus ($512), Lufthansa ($573), and Air Canada ($817).

  • Can I find deals for flights from Des Moines to Brussels that include hotel bookings?

    Yes. In addition to deals on Des Moines to Brussels flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Brussels?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Brussels.

  • Can I find deals for business class flights from Des Moines to Brussels?

    Yes. Cheapflights offers flight deals from Des Moines to Brussels by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Brussels?

    Currently, November is the cheapest month in which you can book a flight from Des Moines to Brussels (average of $614). Flying from Des Moines to Brussels in June is currently the most expensive (average of $1,146). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Des Moines to Brussels

See prices for flight routes from nearby airports that may be better suited for you.
Des Moines to Bruxelles-National flights
Omaha to Bruxelles-National flights

Top airline flying from Des Moines to Brussels

Discover the top airline that operate flights from Des Moines to Brussels. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 25, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$794Average$1,333FlexibilityNo cancel feeOn-time69%

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