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Panama

$142+ Cheap flights from Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/2. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — MIA
Feb 25 — Mar 41
Tue 2/25
Tue 3/4
1 adult, Economy
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What to know about flights from Panama

Discover essential information about flights departing from Panama, including flight schedules, destinations, airlines operating at the Panama airport, and any specific guidelines or requirements for travelers. Please note that the information is based on the most recent updates available. Data last updated February 20, 2025.

Good round-trip deal

$32 or less

Good one-way deal

$37 or less
Price to beat on a round-trip flight from Panama.
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Price to beat on a one-way flight from Panama.
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Find flights from Panama

Cheapest flights from Panama
Explore the most affordable flight options available from Panama. Find the lowest fares based on data from user searches, with prices last updated on February 20, 2025.

Mon 3/171:30 pmPTY - MDE
1 stop4h 39mAvianca
Tue 3/186:00 pmMDE - PTY
Nonstop1h 15mAvianca
Deal found 2/20$238
Mon 3/179:09 amPTY - MDE
Nonstop1h 24mCopa Airlines
Tue 3/185:05 amMDE - PTY
Nonstop1h 29mCopa Airlines
Deal found 2/20$250
Sat 3/812:37 pmPTY - MIA
Nonstop3h 07mCopa Airlines
Wed 3/122:28 pmMIA - PTY
Nonstop3h 07mCopa Airlines
Deal found 2/20$300
Sat 3/19:55 pmPTY - MIA
1 stop13h 45mAvianca
Thu 3/67:05 amMIA - PTY
1 stop17h 55mAvianca
Deal found 2/20$301
Wed 4/2310:05 pmPTY - MIA
1 stop10h 45mMultiple Airlines
Wed 5/75:19 pmMIA - PTY
Nonstop3h 10mMultiple Airlines
Deal found 2/19$361
Wed 3/121:05 pmPTY - MIA
Nonstop3h 05mAmerican Airlines
Wed 3/2610:05 amMIA - PTY
Nonstop3h 10mAmerican Airlines
Deal found 2/20$364
Tue 3/185:25 pmPTY - ATL
2 stops16h 42mMultiple Airlines
Thu 4/36:00 amATL - PTY
2 stops16h 10mMultiple Airlines
Deal found 2/20$377
Wed 4/169:31 amPTY - MDE
Nonstop1h 25mMultiple Airlines
Sun 4/201:39 amMDE - PTY
1 stop5h 09mMultiple Airlines
Deal found 2/20$379
Fri 5/23:20 pmPTY - ATL
1 stop18h 27mUnited Airlines
Tue 5/209:00 amATL - PTY
1 stop10h 37mUnited Airlines
Deal found 2/19$391
Mon 2/243:19 amPTY - MCO
1 stop8h 56mAvianca
Wed 2/262:40 pmMCO - PTY
1 stop9h 40mAvianca
Deal found 2/20$405
Wed 3/123:19 amPTY - MEX
1 stop20h 36mAvianca
Thu 3/275:00 amMEX - PTY
1 stop15h 00mAvianca
Deal found 2/20$405
Thu 3/275:25 pmPTY - LGA
2 stops20h 05mMultiple Airlines
Wed 4/25:45 amLGA - PTY
2 stops16h 25mMultiple Airlines
Deal found 2/19$418

Find flights from Panama within your budget

Find flights departing from Panama that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on February 20, 2025. In the last 7 days, Cheapflights users made a total of 2,558,603 searches

Fly to

Miami

Route

Depart

Return

Price

Panama CityMedellín

PTY - MDE

PTYMDE

Panama City Tocumen Intl

Mon 3/17

1:30 pm-6:09 pm

1 stop4h 39m

Medellín Jose Maria Cordova Intl

Tue 3/18

6:00 pm-7:15 pm

Nonstop1h 15m

$238

Panama CityMedellín

PTY - MDE

PTYMDE

Panama City Tocumen Intl

Mon 3/17

9:09 am-10:33 am

Nonstop1h 24m

Medellín Jose Maria Cordova Intl

Tue 3/18

5:05 am-6:34 am

Nonstop1h 29m

$250

Panama CityMiami

PTY - MIA

PTYMIA

Panama City Tocumen Intl

Sat 4/5

10:25 am-2:40 pm

Nonstop3h 15m

Miami

Sat 4/12

5:19 pm-7:29 pm

Nonstop3h 10m

$298

Panama CityMiami

PTY - MIA

PTYMIA

Panama City Tocumen Intl

Thu 3/20

5:25 pm-10:00 am

1 stop15h 35m

Miami

Thu 4/17

7:20 pm-10:10 am

1 stop15h 50m

$301

Panama CityMiami

PTY - MIA

PTYMIA

Panama City Tocumen Intl

Fri 7/25

3:20 pm-10:31 pm

1 stop30h 11m

Miami

Mon 7/28

8:40 am-6:37 pm

1 stop10h 57m

$327

Panama CityMiami

PTY - MIA

PTYMIA

Panama City Tocumen Intl

Fri 4/4

5:25 pm-4:00 am

1 stop9h 35m

Miami

Sun 4/13

6:01 am-8:11 am

Nonstop3h 10m

$345

Panama CityMiami

PTY - MIA

PTYMIA

Panama City Tocumen Intl

Wed 3/12

1:05 pm-5:10 pm

Nonstop3h 05m

Miami

Wed 3/26

10:05 am-12:15 pm

Nonstop3h 10m

$364

Panama CityAtlanta

PTY - ATL

PTYATL

Panama City Tocumen Intl

Tue 3/18

5:25 pm-11:07 am

2 stops16h 42m

Atlanta Hartsfield-Jackson

Thu 4/3

6:00 am-9:10 pm

2 stops16h 10m

$377

Panama CityMedellín

PTY - MDE

PTYMDE

Panama City Tocumen Intl

Wed 4/16

9:31 am-10:56 am

Nonstop1h 25m

Medellín Jose Maria Cordova Intl

Sun 4/20

1:39 am-6:48 am

1 stop5h 09m

$379

Panama CityAtlanta

PTY - ATL

PTYATL

Panama City Tocumen Intl

Fri 5/2

3:20 pm-10:47 am

1 stop18h 27m

Atlanta Hartsfield-Jackson

Tue 5/20

9:00 am-6:37 pm

1 stop10h 37m

$391

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/20

Showing 1-10 of 60 results
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Best time to book a flight from Panama

Have a flexible travel schedule? Discover the best time to fly from Panama with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Panama

Get recent, data-driven insights about flights from Panama including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Panama?

Currently, April is the cheapest month in which you can book a flight from Panama (average of $109). Flying from Panama in October will prove the most costly (average of $283). There are multiple factors that influence the price of a flight so comparing airlines, departure airports and times can help keep costs down.

When is the cheapest time to fly from Panama?

Use this chart to determine the cheapest time to fly round-trip from Panama to Miami. Price data was last updated on May 26, 2024.

Those who are seeking the cheapest fare on flights departing from Panama would be wise to consider leaving during Friday mornings when prices are typically at their lowest. When considering other options, price-conscious travelers should avoid Friday at noon when fares are usually the most expensive.

Which airlines fly from Panama?

For flights departing from Panama check dates and pricing for the following: Copa Airlines, American Airlines, Avianca, United Airlines. These airlines depart to the following popular destinations: Miami.

Copa Airlines

Copa Airlines

From $59

Avianca

Avianca

From $109

United Airlines

United Airlines

From $288

Air Panama

Air Panama

From $78

What is the cheapest place to fly to from Panama?

The cheapest city to fly to from Panama is Cali Alfonso B. Aragon Intl, with prices starting at $27. Explore other affordable destinations below.

Cali Alfonso B. Aragon Intl

Cali Alfonso B. Aragon Intl

From $27

Panama City Tocumen Intl

Panama City Tocumen Intl

From $30

David Enrique Malek

David Enrique Malek

From $33

Medellín Jose Maria Cordova Intl

Medellín Jose Maria Cordova Intl

From $54

Airline reviews for flights from Panama

Read reviews and ratings of airlines operating flights from Panama. Gain insights into the quality of service, in-flight amenities, customer experiences, and overall satisfaction to choose the best airline for your Panama travel. Please note that the reviews are sourced from user searches and were last updated on February 20, 2025. In the last 7 days, Cheapflights users made a total of 2,558,603 searches.
Delta
8.0
Very good
8,219 reviews

Comfort

8.0

Entertainment

7.9

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Delta
8.0
Very good
8,219 reviews
Delta
8.0
Very good
8,219 reviews

Comfort

8.0

Entertainment

7.9

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Copa Airlines
7.6
Good
1,510 reviews
Delta
8.0
Very good
8,219 reviews

Comfort

8.0

Entertainment

7.9

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

United Airlines
7.4
Good
8,765 reviews
Delta
8.0
Very good
8,219 reviews

Comfort

8.0

Entertainment

7.9

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
8,219 reviews

Comfort

8.0

Entertainment

7.9

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Avianca
6.8
Okay
2,435 reviews
Delta
8.0
Very good
8,219 reviews

Comfort

8.0

Entertainment

7.9

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

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Related info for your journey

Access useful and relevant information related to your journey from Panama. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated February 20, 2025.

  • What is the cheapest month to fly from Panama?

    April is currently the cheapest month to fly from Panama. At this moment in time October is the most expensive month. These prices are determined by multiple factors and booking in advance can help keep costs down if your schedule is not as flexible.

  • Where are the cheapest places to fly to from Panama?

    Check out the cheapest flights from Panama to embark to:
    Fly from Panama City to Bogotá from $143 round trip
    Fly from Panama City to Medellín from $151 round trip
    Fly from Panama City to Cartagena from $168 round trip
    Fly from Panama City to San José from $238 round trip
    Fly from Panama City to Barranquilla from $239 round trip

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