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Panama

$155+ Cheap flights from Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/20. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — MIA
Apr 20 — Apr 271
Sun 4/20
Sun 4/27
1 adult, Economy
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What to know about flights from Panama

Discover essential information about flights departing from Panama, including flight schedules, destinations, airlines operating at the Panama airport, and any specific guidelines or requirements for travelers. Please note that the information is based on the most recent updates available. Data last updated April 15, 2025.

Good round-trip deal

$37 or less

Good one-way deal

$37 or less
Price to beat on a round-trip flight from Panama.
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Price to beat on a one-way flight from Panama.
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Find flights from Panama

Cheapest flights from Panama
Explore the most affordable flight options available from Panama. Find the lowest fares based on data from user searches, with prices last updated on April 15, 2025.

Fri 5/161:20 pmPTY - EWR
1 stop9h 49mAmerican Airlines
Sun 5/256:04 amEWR - PTY
1 stop7h 15mAmerican Airlines
Deal found 4/14$244
Mon 4/281:15 pmPTY - FLL
2 stops20h 34mAmerican Airlines
Sun 5/47:27 pmFLL - PTY
2 stops17h 52mAmerican Airlines
Deal found 4/14$249
Tue 5/61:20 pmPTY - LAX
2 stops21h 20mAmerican Airlines
Fri 5/91:58 pmLAX - PTY
1 stop20h 21mAmerican Airlines
Deal found 4/15$253
Thu 5/293:20 amPTY - MIA
1 stop8h 10mAvianca
Fri 6/67:55 amMIA - PTY
1 stop9h 35mAvianca
Deal found 4/15$267
Fri 5/26:32 pmPTY - MIA
Nonstop3h 05mCopa Airlines
Mon 5/56:01 amMIA - PTY
Nonstop3h 10mCopa Airlines
Deal found 4/14$268
Sun 6/151:50 pmPTY - MIA
Nonstop3h 05mAmerican Airlines
Fri 6/2012:10 pmMIA - PTY
Nonstop3h 15mAmerican Airlines
Deal found 4/15$276
Sun 5/112:13 pmPTY - MIA
1 stop9h 24mDelta
Wed 5/145:35 amMIA - PTY
1 stop8h 13mDelta
Deal found 4/15$284
Wed 5/73:20 amPTY - CUN
1 stop11h 20mAvianca
Thu 5/223:45 pmCUN - PTY
1 stop8h 25mAvianca
Deal found 4/15$288
Fri 6/137:42 amPTY - CUN
Nonstop2h 48mCopa Airlines
Fri 6/2011:20 amCUN - PTY
Nonstop2h 41mCopa Airlines
Deal found 4/14$317
Thu 4/245:25 pmPTY - MIA
1 stop9h 35mMultiple Airlines
Thu 7/36:05 amMIA - PTY
Nonstop3h 06mMultiple Airlines
Deal found 4/14$334
Wed 5/141:20 pmPTY - LGA
1 stop19h 41mAmerican Airlines
Mon 5/198:00 pmLGA - PTY
2 stops17h 19mAmerican Airlines
Deal found 4/14$346
Thu 4/241:15 pmPTY - JFK
2 stops20h 15mAmerican Airlines
Tue 4/295:25 amJFK - PTY
1 stop7h 50mAmerican Airlines
Deal found 4/15$346

Find flights from Panama within your budget

Find flights departing from Panama that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on April 15, 2025. In the last 7 days, Cheapflights users made a total of 2,558,603 searches

Fly to

Miami

Route

Depart

Return

Price

Panama CityNewark

PTY - EWR

PTYEWR

Panama City Tocumen Intl

Fri 5/16

1:20 pm-12:09 am

1 stop9h 49m

Newark

Sun 5/25

6:04 am-12:19 pm

1 stop7h 15m

$244

Panama CityFort Lauderdale

PTY - FLL

PTYFLL

Panama City Tocumen Intl

Mon 4/28

1:15 pm-10:49 am

2 stops20h 34m

Fort Lauderdale

Sun 5/4

7:27 pm-12:19 pm

2 stops17h 52m

$249

Panama CityLos Angeles

PTY - LAX

PTYLAX

Panama City Tocumen Intl

Tue 5/6

1:20 pm-8:40 am

2 stops21h 20m

Los Angeles

Fri 5/9

1:58 pm-12:19 pm

1 stop20h 21m

$253

Panama CityMiami

PTY - MIA

PTYMIA

Panama City Tocumen Intl

Thu 5/29

3:20 am-12:30 pm

1 stop8h 10m

Miami

Fri 6/6

7:55 am-4:30 pm

1 stop9h 35m

$267

Panama CityMiami

PTY - MIA

PTYMIA

Panama City Tocumen Intl

Fri 5/2

6:32 pm-10:37 pm

Nonstop3h 05m

Miami

Mon 5/5

6:01 am-8:11 am

Nonstop3h 10m

$268

Panama CityMiami

PTY - MIA

PTYMIA

Panama City Tocumen Intl

Sun 6/15

1:50 pm-5:55 pm

Nonstop3h 05m

Miami

Fri 6/20

12:10 pm-2:25 pm

Nonstop3h 15m

$276

Panama CityMiami

PTY - MIA

PTYMIA

Panama City Tocumen Intl

Sun 5/11

2:13 pm-12:37 am

1 stop9h 24m

Miami

Wed 5/14

5:35 am-12:48 pm

1 stop8h 13m

$284

Panama CityCancún

PTY - CUN

PTYCUN

Panama City Tocumen Intl

Fri 5/2

3:25 am-5:20 pm

1 stop13h 55m

Cancun

Wed 5/7

6:20 pm-8:55 am

1 stop14h 35m

$285

Panama CityCancún

PTY - CUN

PTYCUN

Panama City Tocumen Intl

Fri 6/13

7:42 am-10:30 am

Nonstop2h 48m

Cancun

Wed 6/18

7:00 am-9:41 am

Nonstop2h 41m

$317

Panama CityMiami

PTY - MIA

PTYMIA

Panama City Tocumen Intl

Thu 4/24

5:25 pm-4:00 am

1 stop9h 35m

Miami

Thu 7/3

6:05 am-8:11 am

Nonstop3h 06m

$334

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/15

Showing 1-10 of 60 results
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Best time to book a flight from Panama

Have a flexible travel schedule? Discover the best time to fly from Panama with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Panama

Get recent, data-driven insights about flights from Panama including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Panama?

Currently, April is the cheapest month in which you can book a flight from Panama (average of $174). Flying from Panama in July will prove the most costly (average of $275). There are multiple factors that influence the price of a flight so comparing airlines, departure airports and times can help keep costs down.

When is the cheapest time to fly from Panama?

Use this chart to determine the cheapest time to fly round-trip from Panama to Miami. Price data was last updated on May 26, 2024.

Those who are seeking the cheapest fare on flights departing from Panama would be wise to consider leaving during Friday mornings when prices are typically at their lowest. When considering other options, price-conscious travelers should avoid Friday at noon when fares are usually the most expensive.

Which airlines fly from Panama?

For flights departing from Panama check dates and pricing for the following: Copa Airlines, American Airlines, Avianca, United Airlines. These airlines depart to the following popular destinations: Miami.

Copa Airlines

Copa Airlines

From $58

Avianca

Avianca

From $157

United Airlines

United Airlines

From $252

Air Panama

Air Panama

From $78

What is the cheapest place to fly to from Panama?

The cheapest city to fly to from Panama is Panama City Tocumen Intl, with prices starting at $33. Explore other affordable destinations below.

Panama City Tocumen Intl

Panama City Tocumen Intl

From $33

David Enrique Malek

David Enrique Malek

From $37

Cali Alfonso B. Aragon Intl

Cali Alfonso B. Aragon Intl

From $68

Medellín Jose Maria Cordova Intl

Medellín Jose Maria Cordova Intl

From $68

Airline reviews for flights from Panama

Read reviews and ratings of airlines operating flights from Panama. Gain insights into the quality of service, in-flight amenities, customer experiences, and overall satisfaction to choose the best airline for your Panama travel. Please note that the reviews are sourced from user searches and were last updated on April 15, 2025. In the last 7 days, Cheapflights users made a total of 2,558,603 searches.
Delta
8.0
Very good
7,918 reviews

Crew

8.5

Boarding

8.2

Food

7.3

Entertainment

7.9

Comfort

7.9

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
Delta
8.0
Very good
7,918 reviews
Delta
8.0
Very good
7,918 reviews

Crew

8.5

Boarding

8.2

Food

7.3

Entertainment

7.9

Comfort

7.9

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
Copa Airlines
7.6
Good
1,408 reviews
Delta
8.0
Very good
7,918 reviews

Crew

8.5

Boarding

8.2

Food

7.3

Entertainment

7.9

Comfort

7.9

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
United Airlines
7.4
Good
8,658 reviews
Delta
8.0
Very good
7,918 reviews

Crew

8.5

Boarding

8.2

Food

7.3

Entertainment

7.9

Comfort

7.9

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,918 reviews

Crew

8.5

Boarding

8.2

Food

7.3

Entertainment

7.9

Comfort

7.9

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
Avianca
6.7
Okay
2,313 reviews
Delta
8.0
Very good
7,918 reviews

Crew

8.5

Boarding

8.2

Food

7.3

Entertainment

7.9

Comfort

7.9

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.

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Popular international destinations from Panama

The most popular international flight routes departing from Panama we’ve come across at this time.
Flights from Panama City to Miami
Flights from Panama City to Bogotá
Flights from Panama City to Madrid
Flights from Panama City to Atlanta
Flights from Panama City to Amsterdam
Flights from Panama City to Los Angeles
Flights from Panama City to San José
Flights from Panama City to San Salvador
Flights from Panama City to Mexico City
Flights from Panama City to Cancún
Flights from Panama City to Guatemala City
Flights from Panama City to Cartagena
Flights from Panama City to Managua
Flights from Panama City to San Francisco
Flights from Panama City to Tampa
Flights from Panama City to Lima
Flights from Panama City to Santo Domingo
Flights from Panama City to Boston

Related info for your journey

Access useful and relevant information related to your journey from Panama. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated April 15, 2025.

  • What is the cheapest month to fly from Panama?

    April is currently the cheapest month to fly from Panama. At this moment in time July is the most expensive month. These prices are determined by multiple factors and booking in advance can help keep costs down if your schedule is not as flexible.

  • Where are the cheapest places to fly to from Panama?

    Check out the cheapest flights from Panama to embark to:
    Fly from Panama City to Medellín from $139 round trip
    Fly from Panama City to Bogotá from $140 round trip
    Fly from Panama City to San José from $191 round trip
    Fly from Panama City to Miami from $266 round trip
    Fly from Panama City to Cancún from $288 round trip

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